Malaria tolerance - for whom the cell tolls?

Trends in Parasitology

Volumn 22, Issue 8, 2006, Pages 371-377

  Boutlis, Craig S ^a   Yeo, Tsin W ^a   Anstey, Nicholas M ^a  

^a MENZIES SCHOOL OF HEALTH RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTOXIN; GLYCOSYLPHOSPHATIDYLINOSITOL;

ENDEMIC DISEASE; HOST PARASITE INTERACTION; HUMAN; MALARIA; NONHUMAN; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; HUMANS; IMMUNE TOLERANCE; IMMUNITY, NATURAL; MALARIA; NITRIC OXIDE; PARASITEMIA; SPECIES SPECIFICITY; TOLL-LIKE RECEPTORS;

BACTERIA (MICROORGANISMS);

EID: 33746276916     PISSN: 14714922     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pt.2006.06.002     Document Type: Review

References (83)

1. Sinton J.A. Immunity or tolerance in malarial infections. Proc. R. Soc. Med. 31 (1938) 1298-1302
2. Gatton M.L., and Cheng Q. Evaluation of the pyrogenic threshold for Plasmodium falciparum malaria in naive individuals. Am. J. Trop. Med. Hyg. 66 (2002) 467-473
3. Playfair J.H., et al. The malaria vaccine: anti-parasite or anti-disease?. Immunol. Today 11 (1990) 25-27
4. Riley E.M., et al. Regulating immunity to malaria. Parasite Immunol. 28 (2006) 35-49
5. Marsh K. Immunology of human malaria. In: Gilles H.M., and Warrell D.A. (Eds). Bruce-Chwatt's Essential Malariology. 3rd edn (1993), Little, Brown and Company 60-77
6. Clark I.A., et al. Pathogenesis of malaria and clinically similar conditions. Clin. Microbiol. Rev. 17 (2004) 509-539
7. Snow R.W., and Marsh K. New insights into the epidemiology of malaria relevant for disease control. Br. Med. Bull. 54 (1998) 293-309
8. Bruce M.C., and Day K.P. Cross-species regulation of Plasmodium parasitemia in semi-immune children from Papua New Guinea. Trends Parasitol. 19 (2003) 271-277
9. Duffy P.E., et al. Variant proteins on the surface of malaria-infected erythrocytes - developing vaccines. Trends Parasitol. 17 (2001) 354-356
10. Golgi C. Sull'infezione malarica. Arch. Sci. Med. (Torino) 10 (1886) 109-135
11. Clark I.A., and Cowden W.B. The pathophysiology of falciparum malaria. Pharmacol. Ther. 99 (2003) 221-260
12. Kwiatkowski D., et al. Anti-TNF therapy inhibits fever in cerebral malaria. Q. J. Med. 86 (1993) 91-98
13. Blatteis C.M., et al. Cytokines, PGE2 and endotoxic fever: a re-assessment. Prostaglandins Other Lipid Mediat. 76 (2005) 1-18
14. Schofield L., et al. Glycosylphosphatidylinositol toxin of Plasmodium up-regulates intercellular adhesion molecule-1, vascular cell adhesion molecule-1, and E-selectin expression in vascular endothelial cells and increases leukocyte and parasite cytoadherence via tyrosine kinase-dependent signal transduction. J. Immunol. 156 (1996) 1886-1896
15. Menendez C., et al. Malaria-related anaemia. Parasitol. Today 16 (2000) 469-476
16. Clark I.A., et al. The biological basis of malarial disease. Int. J. Parasitol. 27 (1997) 1237-1249
17. Clark I.A., et al. Possible importance of macrophage-derived mediators in acute malaria. Infect. Immun. 32 (1981) 1058-1066
18. Naik R.S., et al. Glycosylphosphatidylinositol anchors of Plasmodium falciparum: molecular characterization and naturally elicited antibody response that may provide immunity to malaria pathogenesis. J. Exp. Med. 192 (2000) 1563-1576
19. Schofield L., et al. Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria. Nature 418 (2002) 785-789
20. Delorenzi M., et al. Genes for glycosylphosphatidylinositol toxin biosynthesis in Plasmodium falciparum. Infect. Immun. 70 (2002) 4510-4522
21. Liu X., et al. Convergent synthesis of a fully lipidated glycosylphosphatidylinositol anchor of Plasmodium falciparum. J. Am. Chem. Soc. 127 (2005) 5004-5005
22. Biswas S., et al. Antibodies detected against Plasmodium falciparum haemozoin with inhibitory properties to cytokine production. FEMS Microbiol. Lett. 194 (2001) 175-179
23. Pichyangkul S., et al. Plasmodium falciparum pigment induces monocytes to release high levels of tumor necrosis factor-α and interleukin-1β. Am. J. Trop. Med. Hyg. 51 (1994) 430-435
24. Mordmuller B., et al. Neutrophils and monocytes from subjects with the Mediterranean G6PD variant: effect of Plasmodium falciparum hemozoin on G6PD activity, oxidative burst and cytokine production. Eur. Cytokine Netw. 9 (1998) 239-245
25. Schwarzer E., et al. Malaria-parasitized erythrocytes and hemozoin nonenzymatically generate large amounts of hydroxy fatty acids that inhibit monocyte functions. Blood 101 (2003) 722-728
26. Skorokhod O.A., et al. Hemozoin (malarial pigment) inhibits differentiation and maturation of human monocyte-derived dendritic cells: a peroxisome proliferator-activated receptor-γ-mediated effect. J. Immunol. 173 (2004) 4066-4074
27. Perkins D.J., et al. In vivo acquisition of hemozoin by placental blood mononuclear cells suppresses PGE2, TNF-alpha, and IL-10. Biochem. Biophys. Res. Commun. 311 (2003) 839-846
28. Boutlis C.S., et al. Antibodies to Plasmodium falciparum glycosylphosphatidylinositols: inverse association with tolerance of parasitemia in Papua New Guinean children and adults. Infect. Immun. 70 (2002) 5052-5057
29. Boutlis C.S., et al. Immunoglobulin G responses to Plasmodium falciparum glycosylphosphatidylinositols are short-lived and predominantly of the IgG3 subclass. J. Infect. Dis. 187 (2003) 862-865
30. Miller M.J. Observations of the natural history of malaria in the semi-resistant west African. Trans. R. Soc. Trop. Med. Hyg. 52 (1958) 152-168
31. Cox M.J., et al. Dynamics of malaria parasitaemia associated with febrile illness in children from a rural area of Madang, Papua New Guinea. Trans. R. Soc. Trop. Med. Hyg. 88 (1994) 191-197
32. Boutlis C.S., et al. Nitric oxide production and nitric oxide synthase activity in malaria-exposed Papua New Guinean children and adults show longitudinal stability and no association with parasitemia. Infect. Immun. 72 (2004) 6932-6938
33. Smith T., et al. Attributable fraction estimates and case definitions for malaria in endemic areas. Stat. Med. 13 (1994) 2345-2358
34. Rogier C., et al. Evidence for an age-dependent pyrogenic threshold of Plasmodium falciparum parasitemia in highly endemic populations. Am. J. Trop. Med. Hyg. 54 (1996) 613-619
35. Smith T., et al. Relationships between Plasmodium falciparum infection and morbidity in a highly endemic area. Parasitology 109 (1994) 539-549
36. Prybylski D., et al. Parasite density and malaria morbidity in the Pakistani Punjab. Am. J. Trop. Med. Hyg. 61 (1999) 791-801
37. Boisier P., et al. Relationship between parasite density and fever risk in a community exposed to a low level of malaria transmission in Madagascar highlands. Am. J. Trop. Med. Hyg. 67 (2002) 137-140
38. Baird J.K., et al. Age-dependent susceptibility to severe disease with primary exposure to Plasmodium falciparum. J. Infect. Dis. 178 (1998) 592-595
39. Schofield L., and Grau G.E. Immunological processes in malaria pathogenesis. Nat. Rev. Immunol. 5 (2005) 722-735
40. Anstey N.M., et al. Nitric oxide in Tanzanian children with malaria: inverse relationship between malaria severity and nitric oxide production/nitric oxide synthase type 2 expression. J. Exp. Med. 184 (1996) 557-567
41. Anstey N.M., et al. Effects of age and parasitemia on nitric oxide production/leukocyte nitric oxide synthase type 2 expression in asymptomatic, malaria-exposed children. Am. J. Trop. Med. Hyg. 61 (1999) 253-258
42. Clark I.A., et al. Does malarial tolerance, through nitric oxide, explain the low incidence of autoimmune disease in tropical Africa?. Lancet 348 (1996) 1492-1494
43. Iuvone, T. et al. (1996) Nitric oxide inhibits LPS-induced tumor necrosis factor synthesis in vitro and in vivo. Life Sci. 59, PL207-211
44. Zingarelli B., et al. Increased nitric oxide synthesis during the development of endotoxin tolerance. Shock 3 (1995) 102-108
45. Bate C.A., et al. Antibodies against phosphatidylinositol and inositol monophosphate specifically inhibit tumour necrosis factor induction by malaria exoantigens. Immunology 76 (1992) 35-41
46. Boutlis C.S., et al. Nitric oxide production and mononuclear cell nitric oxide synthase activity in malaria-tolerant Papuan adults. Infect. Immun. 71 (2003) 3682-3689
47. Boutlis C.S., et al. Inducible nitric oxide synthase (NOS2) promoter CCTTT repeat polymorphism: relationship to in vivo nitric oxide production/NOS activity in an asymptomatic malaria-endemic population. Am. J. Trop. Med. Hyg. 69 (2003) 569-573
48. Bate C.A., et al. Malaria exoantigens induce T-independent antibody that blocks their ability to induce TNF. Immunology 70 (1990) 315-320
49. Bate C.A., and Kwiatkowski D. Inhibitory immunoglobulin M antibodies to tumor necrosis factor-inducing toxins in patients with malaria. Infect. Immun. 62 (1994) 3086-3091
50. Al Yaman F., et al. Acquired antibody levels to Plasmodium falciparum merozoite surface antigen 1 in residents of a highly endemic area of Papua New Guinea. Trans. R. Soc. Trop. Med. Hyg. 89 (1995) 555-559
51. Johnson A., et al. Interaction of HLA and age on levels of antibody to Plasmodium falciparum rhoptry-associated proteins 1 and 2. Infect. Immun. 68 (2000) 2231-2236
52. de Souza J.B., et al. Prevalence and boosting of antibodies to Plasmodium falciparum glycosylphosphatidylinositols and evaluation of their association with protection from mild and severe clinical malaria. Infect. Immun. 70 (2002) 5045-5051
53. Hudson Keenihan S.N., et al. Age-dependent impairment of IgG responses to glycosylphosphatidylinositol with equal exposure to Plasmodium falciparum among Javanese migrants to Papua, Indonesia. Am. J. Trop. Med. Hyg. 69 (2003) 36-41
54. Suguitan Jr. A.L., et al. Lack of an association between antibodies to Plasmodium falciparum glycosylphosphatidylinositols and malaria-associated placental changes in Cameroonian women with preterm and full-term deliveries. Infect. Immun. 72 (2004) 5267-5273
55. Boutlis C.S., et al. Glycosylphosphatidylinositols in malaria pathogenesis and immunity: potential for therapeutic inhibition and vaccination. In: Langhorne J. (Ed). Immunology and Immunopathology of Malaria (2005), Springer-Verlag 145-185
56. Bennett Jr. I.L., and Beeson P.B. The properties and biologic effects of bacterial pyrogens. Medicine (Baltimore) 29 (1950) 365-400
57. Favorite G.O., and Morgan H.R. Effects produced by the intravenous injection in man of a toxic antigenic material derived from Eberthella typhosa: Clinical, hematological, chemical and serological studies. J. Clin. Invest. 21 (1942) 589-599
58. van der Poll T., and van Deventer S.J.H. Endotoxemia in healthy subjects as a human model of inflammation. In: Marshall J.C., and Cohen J. (Eds). Update in Intensive Care and Emergency Medicine. 1st edn (1999), Springer-Verlag 335-357
59. West M.A., and Heagy W. Endotoxin tolerance: a review. Crit. Care Med. 30 (2002) S64-S73
60. Miller S.I., et al. LPS, TLR4 and infectious disease diversity. Nat. Rev. Microbiol. 3 (2005) 36-46
61. Dobrovolskaia M.A., and Vogel S.N. Toll receptors, CD14, and macrophage activation and deactivation by LPS. Microbes Infect. 4 (2002) 903-914
62. Fan H., and Cook J.A. Molecular mechanisms of endotoxin tolerance. J. Endotoxin Res. 10 (2004) 71-84
63. Calvano S.E., et al. A network-based analysis of systemic inflammation in humans. Nature 437 (2005) 1032-1037
64. Heyman A., and Beeson P.B. Influence of various disease states upon the febrile response to intravenous injection of typhoid bacterial pyrogen: with particular reference to malaria and cirrhosis of the liver. J. Lab. Clin. Med. 34 (1949) 1400-1403
65. Rubenstein M., et al. Malaria induced endotoxin tolerance. Proc. Soc. Exp. Biol. Med. 118 (1965) 283-287
66. Zingarelli B., et al. Inducible nitric oxide synthase is not required in the development of endotoxin tolerance in mice. Shock 17 (2002) 478-484
67. Krishnegowda G., et al. Induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols (GPIs) of Plasmodium falciparum: Cell signaling receptors, GPI structural requirement, and regulation of GPI activity. J. Biol. Chem. 280 (2004) 8606-8616
68. Zhu J., et al. Induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols of Plasmodium falciparum: the requirement of extracellular signal-regulated kinase, p38, c-Jun N-terminal kinase and NF-κB pathways for the expression of proinflammatory cytokines and nitric oxide. J. Biol. Chem. 280 (2005) 8617-8627
69. Ropert C., and Gazzinelli R.T. Regulatory role of Toll-like receptor 2 during infection with Trypanosoma cruzi. J. Endotoxin Res. 10 (2004) 425-430
70. Oliveira A.C., et al. Expression of functional TLR4 confers proinflammatory responsiveness to Trypanosoma cruzi glycoinositolphospholipids and higher resistance to infection with T. cruzi. J. Immunol. 173 (2004) 5688-5696
71. Coban C., et al. Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin. J. Exp. Med. 201 (2005) 19-25
72. Lehner M.D., et al. Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators. J. Immunol. 166 (2001) 5161-5167
73. Beutler E., et al. Synergy between TLR2 and TLR4: a safety mechanism. Blood Cells Mol. Dis. 27 (2001) 728-730
74. Ropert C., et al. Requirement of mitogen-activated protein kinases and I kappa B phosphorylation for induction of proinflammatory cytokines synthesis by macrophages indicates functional similarity of receptors triggered by glycosylphosphatidylinositol anchors from parasitic protozoa and bacterial lipopolysaccharide. J. Immunol. 166 (2001) 3423-3431
75. van der Kleij D., et al. Responses to Toll-like receptor ligands in children living in areas where schistosome infections are endemic. J. Infect. Dis. 189 (2004) 1044-1051
76. Kane C.M., et al. Helminth antigens modulate TLR-initiated dendritic cell activation. J. Immunol. 173 (2004) 7454-7461
77. Nebl T., et al. Stimulation of innate immune responses by malarial glycosylphosphatidylinositol via pattern recognition receptors. Parasitology 130 Suppl (2005) S45-S62
78. Murray J., et al. The biological suppression of malaria: an ecological and nutritional interrelationship of a host and two parasites. Am. J. Clin. Nutr. 31 (1978) 1363-1366
79. Su Z., et al. Impairment of protective immunity to blood-stage malaria by concurrent nematode infection. Infect. Immun. 73 (2005) 3531-3539
80. Nacher M. Interactions between worm infections and malaria. Clin. Rev. Allergy Immunol. 26 (2004) 85-92
81. Le Hesran J.Y., et al. Severe malaria attack is associated with high prevalence of Ascaris lumbricoides infection among children in rural Senegal. Trans. R. Soc. Trop. Med. Hyg. 98 (2004) 397-399
82. Zimmerman P.A., et al. Why do we need to know more about mixed Plasmodium species infections in humans?. Trends Parasitol. 20 (2004) 440-447
83. Tulic M.K., et al. Role of toll-like receptor 4 in protection by bacterial lipopolysaccharide in the nasal mucosa of atopic children but not adults. Lancet 363 (2004) 1689-1697