Variant proteins on the surface of malaria-infected erythrocytes - Developing vaccines

Trends in Parasitology

Volumn 17, Issue 8, 2001, Pages 354-356

  Duffy, Patrick E ^a   Craig, Alister G ^b   Baruch, Dror I ^c  

^a SEATTLE BIOMEDICAL RESEARCH INSTITUTE   (United States)

^b LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CD36 ANTIGEN; CHONDROITIN 4 SULFATE; ERYTHROCYTE MEMBRANE PROTEIN 1; INTERCELLULAR ADHESION MOLECULE 1; MALARIA VACCINE; MEMBRANE ANTIGEN; PROTEIN CIDR1ALPHA; PROTEIN DBL1ALPHA; PROTEIN DBL1GAMMA; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; CELL ADHESION; CONFERENCE PAPER; EXON; GENE SEQUENCE; GENOME; HAPLOIDY; HOST; HUMAN; IMMUNITY; IMMUNIZATION; MALARIA FALCIPARUM; MEIOSIS; MITOSIS; PHYLOGENY; PLASMODIUM FALCIPARUM; TELOMERE;

ANIMALS; ANTIGENIC VARIATION; ERYTHROCYTE MEMBRANE; FEMALE; HUMANS; MALARIA VACCINES; MALARIA, FALCIPARUM; PLASMODIUM FALCIPARUM; PREGNANCY; PREGNANCY COMPLICATIONS, PARASITIC; PROTOZOAN PROTEINS;

EID: 0035414312     PISSN: 14714922     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1471-4922(01)02022-0     Document Type: Conference Paper

References (9)

1. Parasite antigens on the infected red cell surface are targets for naturally acquired immunity to malaria
2. Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is a common adhesive phenotype and is associated with severe malaria
3. Maternal antibodies block malaria
4. The adhesion of Plasmodium falciparum-infected erythrocytes to chondroitin sulfate A is mediated by P. falciparum erythrocyte membrane protein 1
5. Frequent ectopic recombination of virulence factor genes in telomeric chromosome clusters of P. falciparum
6. Classification of adhesive domains in the Plasmodium falciparum erythrocyte membrane protein 1 family
7. Modifications in the CD36 binding domain of the Plasmodium falciparum variant antigen are responsible for the inability of chondroitin sulfate A adherent parasites to bind CD36
8. Cytoadhesion of Plasmodium falciparum ring-stage-infected erythrocytes
9. Plasmodium falciparum-infected erythrocytes: Agglutination by diverse Kenyan plasma is associated with severe disease and young host age