Role of toll-like receptor 4 in protection by bacterial lipopolysaccharide in the nasal mucosa of atopic children but not adults

Lancet

Volumn 363, Issue 9422, 2004, Pages 1689-1697

  Tulic, Meri K ^a,c   Fiset, Pierre Olivier ^a   Manoukian, John J ^a   Frenkiel, Saul ^b   Lavigne, François ^a   Eidelman, David H ^a   Hamid, Qutayba ^a  

^a NOTRE DAME HOSPITAL   (Canada)

^b MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; BACTERIUM LIPOPOLYSACCHARIDE; CD3 ANTIGEN; CD4 ANTIGEN; CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 10 ANTIBODY; INTERLEUKIN 2 RECEPTOR; TOLL LIKE RECEPTOR 4;

ADULT; ARTICLE; ATOPY; CELL CULTURE; CELL PROLIFERATION; CELL STIMULATION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; EXPOSURE; FEMALE; HELPER CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; NOSE MUCOSA; PHENOTYPE; PRIORITY JOURNAL; PROTECTION; PROTEIN EXPRESSION; PROTEIN FUNCTION; UPREGULATION;

EID: 2442686409     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(04)16253-3     Document Type: Article

References (33)

1. Cookson WOCM, Moffatt MF. Asthma: an epidemic in the absence of infection? Science. 275:1997;41
2. Stein RT, Sherrill D, Morgan WJ, et al. Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years. Lancet. 354:1999;541-545
3. Holt PG. Environmental factors and primary T-cell sensitisation to inhalant allergens in infancy: reappraisal of the role of infections and air pollution. Pediatr Allergy Immunol. 6:1995;1-10
4. Von Ehrenstein OS, Von Mutius E, Illi S, Baumann L, Bohm O, von Kries R. Reduced risk of hay fever and asthma among children of farmers. Clin Exp Allergy. 30:2000;187-193
5. Riedler J, Eder W, Oberfeld G, Schreuer M. Austrian children living on a farm have less hay fever, asthma and allergic sensitization. Clin Exp Allergy. 30:2000;194-200
6. Kilpelainen M, Terho EO, Helenius H, Koskenvuo M. Farm environment in childhood prevents the development of allergies. Clin Exp Allergy. 30:2000;201-208
7. Braun-Fahrlander C, Gassner M, Sennhauser F, Wuthrich B, Team TS. Lower risk of allergic sensitisation and hay fever in farmers' children in Switzerland. Epidemiology. 7:1996;S47
8. Tulic MK, Wale JL, Holt PG, Sly PD. Modification of the inflammatory response to allergen challenge following exposure to bacterial lipopolysaccharide. Am J Respir Cell Mol Biol. 22:2000;604-612
9. Tulic MK, Holt PG, Sly PD. Modification of acute and late-phase allergic responses to ovalbumin with lipopolysaccharide. Int Arch Allergy Immunol. 129:2002;119-128
10. Tulic MK, Manoukian JJ, Eidelman DH, Hamid Q. T cell proliferation induced by local application of lipopolysaccharide in the nasal mucosa of non-atopic children. J Allergy Clin Immunol. 110:2002;771-776
11. Giaid A, Michel RP, Stewart DJ, Sheppard M, Corrin B, Hamid Q. Expression of endothelin-1 in lungs of patients with cryptogenic fibrosing alveolitis. Lancet. 341:1993;1550-1554
12. Hamid Q, Azzawi M, Ying S, et al. Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma. J Clin Invest. 87:1991;1541-1546
13. Hamid Q, Wharton J, Terenghi G, et al. Localization of atrial natriuretic peptide mRNA and immunoreactivity in the rat heart and human atrial appendage. Proc Natl Acad Sci USA. 84:1987;6760-6764
14. Rassa JC, Meyers JL, Zhang Y, Kudaravalli R, Ross SR. Murine retroviruses activate B cells via interaction with toll-like receptor 4. Proc Natl Acad Sci USA. 99:2002;2281-2286
15. Caramalho I, Lopes-Carvalho T, Ostler D, Zelenay S, Haury M, Demengeot J. Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide. J Exp Med. 197:2003;403-411
16. Fiset PO, Soussi-Gounni A, Christodoulopoulos P, et al. Modulation of allergic response in nasal mucosa by antisense oligodeoxynucleotides for IL-4. J Allergy Clin Immunol. 111:2003;580-586
17. Tulic MK, Knight DA, Holt PG, Sly PD. Lipopolysaccharide inhibits the late-phase response to allergen by altering nitric oxide synthase activity and interleukin-10. Am J Respir Cell Mol Biol. 24:2001;640-646
18. Gerhold K, Blumchen K, Bock A, et al. Endotoxins prevent murine IgE production, Th2 immune responses, and development of airway eosinophilia but not airway hyperreactivity. J Allergy Clin Immunol. 110:2002;110-116
19. Rylander R, Bake B, Fischer JJ, Helander IM. Pulmonary function and symptoms after inhalation of endotoxin. Am Rev Respir Dis. 140:1989;981-986
20. Peden DB, Tucker K, Murphy P, et al. Eosinophil influx to the nasal airway after local low-level LPS challenge in humans. J Allergy Clin Immunol. 104:1999;388-394
21. Yssel H, de Waal Malefyt R, Roncarolo MG, et al. Interleukin 10 is produced by subsets of human CD4+ T cell clones and peripheral blood T cells. J Immunol. 149:1992;2378-2384
22. Annacker O, Pimenta-Araujo R, Burlen-Defranoux O, Barbosa TC, Cumano A, Bandeira A. CD25+CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10. J Immunol. 166:2001;3008-3018
23. de Waal Malefyt R, Haanen J, Spits H, et al. Interleukin 10 (IL-10) and viral-IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via down-regulation of class-II major histocompatibility complex expression. J Exp Med. 174:1991;915-924
24. Oh JW, Seroogy CM, Meyer EH, et al. CD4 T-helper cells engineered to produce IL-10 prevent allergen-induced airway hyperreactivity and inflammation. J Allergy Clin Immunol. 110:2002;460-468
25. Nomura F, Akashi S, Sakao Y, et al. Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression. J Immunol. 164:2000;3476-3479
26. Renshaw M, Rockwell J, Engleman C, Gewirtz A, Katz J, Sambhara S. Cutting edge: impaired toll-like receptor expression and function in aging. J Immunol. 169:2002;4697-4701
27. Schwartz DA. The role of TLR4 in endotoxin responsiveness in humans. J Endotoxin Res. 7:2001;389-393
28. Arbour NC, Lorenz E, Schutte BC, et al. TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat Genet. 25:2000;187-191
29. Chow JC, Young DW, Golenbock DT, Christ WJ, Gusovsky F. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. J Biol Chem. 274:1999;10689-10692
30. Hornung V, Rothenfusser S, Britsch S, et al. Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J Immunol. 168:2002;4531-4537
31. Cohen L, Haziot A, Shen DR, et al. CD14-independent responses to LPS require a serum factor that is absent from neonates. J Immunol. 155:1995;5337-5342
32. Eisenbarth SC, Piggott DA, Huleatt JW, Visintin I, Herrick CA, Bottomly K. Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J Exp Med. 196:2002;1645-1651
33. Dabbagh K, Dahl ME, Stepick-Biek P, Lewis DB. Toll-like receptor 4 is required for optimal development of Th2 immune responses: role of dendritic cells. J Immunol. 168:2002;4524-4530