Probing the structure of the warfarin-binding site on human serum albumin using site-directed mutagenesis

Proteins: Structure, Function and Genetics

Volumn 47, Issue 2, 2002, Pages 116-125

  Petersen, Charles E ^a   Ha, Chung Eun ^a   Curry, Stephen ^b   Bhagavan, Nadhipuram V ^a  

^a UNIVERSITY OF HAWAII   (United States)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Amino acids; Binding site; Drug; Human serum albumin; Ligand; N B transition; Warfarin

Indexed keywords

AMINO ACID; HUMAN SERUM ALBUMIN; WARFARIN;

AQUEOUS SOLUTION; ARTICLE; BINDING SITE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; DISSOCIATION CONSTANT; FLUORESCENCE ANALYSIS; HUMAN; PH; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; SERUM ALBUMIN; SPECTROMETRY, FLUORESCENCE; WARFARIN;

EID: 0036568334     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.10068     Document Type: Article

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