Unique T cell proliferation associated with PKCμ activation and impaired ZAP-70 phosphorylation in recognition of overexpressed HLA/partially agonistic peptide complexes

European Journal of Immunology

Volumn 33, Issue 6, 2003, Pages 1497-1507

  Irie, Atsushi ^a   Chen, Yu Zhen ^a   Tsukamoto, Hirotake ^a   Jotsuka, Toko ^a   Masuda, Masako ^a   Nishimura, Yasuharu ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Altered peptide ligand; Protein kinase C ; Protein kinase D; T cell activation; ZAP 70

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; 2 [1 (3 DIMETHYLAMINOPROPYL) 5 METHOXY 1H INDOL 3 YL] 3 (1H INDOL 3 YL)MALEIMIDE; CD4 ANTIGEN; CELL PROTEIN; HLA DR4 ANTIGEN; LIGAND; PARTIAL AGONIST; PHOSPHOTRANSFERASE; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; PROTEIN KINASE ZAP 70; T LYMPHOCYTE RECEPTOR; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ANTIGEN RECOGNITION; ARTICLE; CELL DENSITY; COMPLEX FORMATION; CONTROLLED STUDY; COVALENT BOND; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HLA SYSTEM; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IN VITRO STUDY; LANGERHANS CELL; LYMPHOCYTE ACTIVATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN PHOSPHORYLATION; RECEPTOR AFFINITY; SIGNAL TRANSDUCTION; STREPTOCOCCUS; T LYMPHOCYTE; UPREGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; ANION EXCHANGE PROTEIN 1, ERYTHROCYTE; ANTIGEN PRESENTATION; ANTIGENS, BACTERIAL; BACTERIAL OUTER MEMBRANE PROTEINS; CARBAZOLES; CARRIER PROTEINS; CD4-POSITIVE T-LYMPHOCYTES; CELL DIVISION; CELLS, CULTURED; COCULTURE TECHNIQUES; ENZYME ACTIVATION; ENZYME INHIBITORS; HLA-DR4 ANTIGEN; HUMANS; INDOLES; JURKAT CELLS; L CELLS (CELL LINE); LIGANDS; LYMPHOCYTE ACTIVATION; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-TYROSINE KINASES; RECEPTORS, ANTIGEN, T-CELL; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; T-LYMPHOCYTE SUBSETS; TRANSFECTION; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 0038759079     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200323618     Document Type: Article

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