Cationic long-chain ceramide LCL-30 induces cell death by mitochondrial targeting in SW403 cells

Molecular Cancer Therapeutics

Volumn 5, Issue 6, 2006, Pages 1520-1529

  Dindo, Daniel ^a   Dahm, Felix ^a   Szulc, Zdzislaw ^b   Bielawska, Alicja ^b   Obeid, Lina M ^b,c   Hannun, Yusuf A ^b   Graf, Rolf ^a   Clavien, Pierre Alain ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c RALPH H JOHNSON VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 9; CERAMIDE DERIVATIVE; CYTOCHROME C; DOXORUBICIN; LCL 30; OMEGA PYRIDINIUM BROMIDE DEXTRO ERYTHRO C16 CERAMIDE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE KINASE; UNCLASSIFIED DRUG;

ARTICLE; CARCINOMA CELL; CELL DEATH; COLON CARCINOMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DISTRIBUTION; DRUG MECHANISM; DRUG POTENTIATION; DRUG SELECTIVITY; DRUG TARGETING; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN SECRETION; TARGET CELL; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE; WESTERN BLOTTING;

ANTIBIOTICS, ANTINEOPLASTIC; CASPASE 3; CASPASE 9; CASPASES; CATIONS; CELL DEATH; CERAMIDES; COLONIC NEOPLASMS; CYTOCHROMES C; DOXORUBICIN; DRUG COMBINATIONS; DRUG SYNERGISM; ENZYME ACTIVATION; HUMANS; LYSOPHOSPHOLIPIDS; MEMBRANE POTENTIALS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; SPHINGOSINE; TUMOR CELLS, CULTURED;

EID: 33746056492     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-05-0513     Document Type: Article

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