Interaction of the mitotic inhibitor monastrol with human kinesin Eg5

Biochemistry

Volumn 42, Issue 2, 2003, Pages 338-349

  DeBonis, Salvatore ^a   Simorre, Jean Pierre ^a   Crevel, Isabelle ^b   Lebeau, Luc ^c   Skoufias, Dimitrios A ^a   Blanzy, Anne ^d   Ebel, Christine ^a   Gans, Pierre ^a   Cross, Robert ^b   Hackney, David D ^e   Wade, Richard H ^a   Kozielski, Frank ^a  

^a INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^b MARIE CURIE RESEARCH INSTITUTE   (United Kingdom)

^c UNIVERSITÉ DE STRASBOURG   (France)

^d Centre National de la Recherche Scientifique   (France)

^e CARNEGIE MELLON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; CELLS; ENZYME INHIBITION; ENZYMES; NUCLEAR MAGNETIC RESONANCE;

MITOTIC SPINDLE;

PROTEINS;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; ANTIMITOTIC AGENT; KINESIN; MONASTROL; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; HUMAN; MITOSIS INHIBITION; MITOSIS SPINDLE; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN DOMAIN;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; ANTHRANILIC ACIDS; CATTLE; DOSE-RESPONSE RELATIONSHIP, DRUG; DYNEIN ATPASE; ENZYME ACTIVATION; GROWTH INHIBITORS; HELA CELLS; HUMANS; INHIBITORY CONCENTRATION 50; KINESIN; MICROSCOPY, INTERFERENCE; MICROSCOPY, VIDEO; MICROTUBULES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, TERTIARY; PYRIMIDINES; SEQUENCE DELETION; SODIUM CHLORIDE; STEREOISOMERISM; THIONES;

ASPERGILLUS; CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; EMERICELLA NIDULANS; HOMO SAPIENS; MELANOGASTER; NEUROSPORA CRASSA; VERTEBRATA;

EID: 0037457808     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi026716j     Document Type: Article

References (49)

1. Bloom, G. S., and Endow, S. A. (1995) Protein Profile 2, 1105-1171.
2. Kim, A. J., and Endow, S. A. (2000) J. Cell Sci. 113, 3681-3682.
3. Miki, H., Setoy, M., Kaneshira, K., and Hirokawa, N. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 7004-7011.
4. Ray, K., and Goldstein, L. S. B. (1999) Guidebook to the Cytoskeletal and Motor Proteins. 2nd ed., pp 389-394, Oxford University Press, Oxford.
5. Kashina, A. S., Baskin, R. J., Cole, D. G., Wedaman, K. P., Saxton, W. M., and Scholey, J. M. (1996) Nature 379, 270-272.
6. Gordon, D. M., and Roof, D. M. (1999) J. Biol. Chem. 274, 28779-28786.
7. Mountain, V., Simerly, C., Howard, L., Ando, A., Schatten, G., and Compton, D. A. (1999) J. Cell Biol. 147, 351-366.
8. Blangy, A., Lane, H. A., d'Hérin, P., Harper, M., Kress, M., and Nigg, E. A. (1995) Cell 83, 1159-1169.
9. Blangy, A., Arnaud, L., and Nigg, E. A. (1997) J. Biol. Chem. 272, 19418-19424.
10. Kapoor, T. M., and Mitchison, T. J. (2001) J. Cell Biol. 154, 1125-1134.
11. Mayer, T. U., Kapoor, T. M., Haggarty, S. J., King, R. W., Schreiber, S. L., and Mitchison, T. J. (1999) Science 286, 971-974.
12. Haggarty, S. J., Mayer, T. U., Miyamoto, D. T., Fathi, R., King, R. W., Michison, T. J., and Schreiber, S. L. (2000) Chem. Biol. 7, 275-286.
13. Kapoor, T. M., Mayer, T. U., Coughlin, M. L., and Mitchison, T. J. (2000) J. Cell Biol. 150, 975-988.
14. Jordan, A., Hadfield, J. A., and McGown, N. J. L. (1998) Med. Res. Rev. 18, 259-296.
15. Turner, J., Anderson, R., Guo, J., Beraud, C., Fletterick, R., and Sakowicz, R. (2001) J. Biol. Chem. 276, 25496-25502.
16. Hackney, D. D., and Jiang, W. (2001) Methods Mol. Biol. 164, 65-71.
17. Laemmli, U. K. (1970) Nature 227, 680-685.
18. Svergun, D. I., Zaccai, G., Malfois, M., Wade, R. H., Koch, M. H., and Kozielski, F. (2001) J. Biol. Chem. 276, 24826-24832.
19. Kozielski, F., Svergun, D., Zaccai, G., Wade, R. H., and Koch, M. H. (2001) J. Biol. Chem. 276, 1267-1275.
20. Krylyshkina, O., Kaverina, I., Kranewitter, W., Steffen, W., Alonso, M. C., Cross, R. A., and Small, J. V. (2002) J. Cell Biol. 156, 349-359.
21. Crevel, I. M., Lockhart, A., and Cross, R. A. (1997) J. Mol. Biol. 273, 160-170.
22. Cross, R. A. (1998) Microtubule Mobility Assays, in Cell Biology: a Laboratory Handbook (Celis, J. E., Ed.) 2nd ed., Vol. 2, pp 317-326, Academic Press, San Diego, CA.
23. Lewandowski, K., Murer, P., Svec, F., and Fréchet, J. M. (1999) J. Comb. Chem. 1, 105-112.
24. Kappe, C. O., Shishkin, O. V., Uray, G., and Verdino, P. (2000) Tetrahedron 56, 1859-1862.
25. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254.
26. Hajduk, P. J., Olejniczak, E. T., and Fesik, S. (1997) J. Am. Chem. Soc. 119, 12257-12261.
27. Chandra, R., Salmon, E. D., Erickson, H. P., Lockhart, A., and Endow, S. A. (1993) J. Biol. Chem. 268, 9005-9013.
28. Schuck, P. (1998) Biophys. J. 75, 1503-1512.
29. Schuck, P., and Demeler, B. (1999) Biophys. J. 76, 2288-2296.
30. Schuck, P. (2000) Biophys. J. 78, 1606-1619.
31. Cheng, J. Q., Jiang, W., and Hackney, D. D. (1998) Biochemistry 37, 5288-5295.
32. Hackney, D. D. (2002) Biochemistry 41, 4437-4446.
33. Hwang, T. L., and Shaka, A. S. (1995) J. Magn. Reson. A 112, 275-279.
34. Gill, S. C., and von Hippel, P. H. (1989) Anal. Biochem. 182, 319-326.
35. Lin, M., Shapiro, M., and Wareing, J. (1997) J. Am. Chem. Soc. 119, 5249-5250.
36. Gibbs, S. J., and Johnson, C. S. (1991) J. Magn. Reson. 93, 295-402.
37. Hirel, P. H., Schmitter, M. J., Dessen, P., Fayat, G., and Blanquet, S. (1989) Proc. Natl. Acad. Sci. U.S.A. 86, 8247-8251.
38. Foster, K. A., Correia, J. J., and Gilbert, S. P. (1998) J. Biol. Chem. 273, 35307-35318.
39. Hajduk, P., Meadows, R. P., and Fesik, S. (1999) Q. Rev. Biophys. 32, 211-240.
40. Shuker, S., Hajduk, P., Meaedows, R. P., and Fesik, S. (1996) Science 274, 1531-1534.
41. Blangy, A., Chaussepied, P., and Nigg, E. A. (1998) Cell Motil. Cytoskel. 40, 174-182.
42. Lockhart, A., and Cross, R. A. (1996) Biochemistry 35, 2365-2373.
43. Lockhart, A., and Cross, R. A. (1994) EMBO J. 13, 751-757.
44. Shimizu, T., Sablin, E., Vale, R. D., Fletterick, R., Pechnatnikova, E., and Taylor, E. W. (1995) Biochemistry 34, 13259-13266.
45. Ma, Y. Z., and Taylor, E. W. (1995) Biochemistry 34, 13242-13251.
46. Jiang, W., Stock, M. F., Li, X., and Hackney, D. D. (1997) J. Biol. Chem. 272, 7626-7632.
47. Hackney, D. D., and Stock, M. F. (2000) Nat. Cell Biol. 2, 257-260.
48. Bhushan, R., and Martens, J. (1998) Biomed. Chromatogr. 12, 309-316.
49. Hoglund, P., Erikssonm, T., and Bjorkman, S. J. (1998) Pharmacokinet. Biopharm. 26, 363-383.