메뉴 건너뛰기




Volumn 12, Issue 12, 2006, Pages 3851-3855

PIK3CA mutations in intraductal papillary mucinous neoplasm/carcinoma of the pancreas

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; PHOSPHATIDYLINOSITOL 3 KINASE;

EID: 33745725763     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-06-0292     Document Type: Article
Times cited : (142)

References (49)
  • 1
    • 0036142203 scopus 로고    scopus 로고
    • Intraductal papillary-mucinous neoplasms of the pancreas: An analysis of in situ and invasive carcinomas in 28 patients
    • Adsay NV, Conlon KC, Zee SY, Brennan MF, Klimstra DS. Intraductal papillary-mucinous neoplasms of the pancreas: an analysis of in situ and invasive carcinomas in 28 patients. Cancer 2002;94:62-77.
    • (2002) Cancer , vol.94 , pp. 62-77
    • Adsay, N.V.1    Conlon, K.C.2    Zee, S.Y.3    Brennan, M.F.4    Klimstra, D.S.5
  • 2
    • 1242341489 scopus 로고    scopus 로고
    • Intraductal papillary mucinous neoplasms of the pancreas: An analysis of clinicopathologic features and outcome
    • D'Angelica M, Brennan MF, Suriawinata AA, Klimstra D, Conlon KC. Intraductal papillary mucinous neoplasms of the pancreas: an analysis of clinicopathologic features and outcome. Ann Surg 2004;239:400-8.
    • (2004) Ann Surg , vol.239 , pp. 400-408
    • D'Angelica, M.1    Brennan, M.F.2    Suriawinata, A.A.3    Klimstra, D.4    Conlon, K.C.5
  • 3
    • 0030886967 scopus 로고    scopus 로고
    • Intraductal papillary tumors and mucinous cystic tumors of the pancreas: Clinicopathologic study of 38 cases
    • Fukushima N, Mukai K, Kanai Y, et al. Intraductal papillary tumors and mucinous cystic tumors of the pancreas: clinicopathologic study of 38 cases. Hum Pathol 1997;28:1010-7.
    • (1997) Hum Pathol , vol.28 , pp. 1010-1017
    • Fukushima, N.1    Mukai, K.2    Kanai, Y.3
  • 4
    • 0028902553 scopus 로고
    • Intraductal papillary mucinous neoplasms of the pancreas associated with so-called "mucinous ductal ectasia". Histochemical and immunohistochemical analysis of 29 cases
    • Nagai E, Ueki T, Chijiiwa K, Tanaka M, Tsuneyoshi M. Intraductal papillary mucinous neoplasms of the pancreas associated with so-called "mucinous ductal ectasia". Histochemical and immunohistochemical analysis of 29 cases. Am J Surg Pathol 1995;19:576-89.
    • (1995) Am J Surg Pathol , vol.19 , pp. 576-589
    • Nagai, E.1    Ueki, T.2    Chijiiwa, K.3    Tanaka, M.4    Tsuneyoshi, M.5
  • 5
    • 3242744313 scopus 로고    scopus 로고
    • An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms
    • Hruban RH, Takaori K, Klimstra DS, et al. An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms. Am J Surg Pathol 2004;28:977-87.
    • (2004) Am J Surg Pathol , vol.28 , pp. 977-987
    • Hruban, R.H.1    Takaori, K.2    Klimstra, D.S.3
  • 6
    • 0034495006 scopus 로고    scopus 로고
    • Dpc-4 protein is expressed in virtually all human intraductal papillary mucinous neoplasms of the pancreas: Comparison with conventional ductal adenocarcinomas
    • Iacobuzio-Donahue CA, Klimstra DS, Adsay NV, et al. Dpc-4 protein is expressed in virtually all human intraductal papillary mucinous neoplasms of the pancreas: comparison with conventional ductal adenocarcinomas. Am J Pathol 2000;157:755-61.
    • (2000) Am J Pathol , vol.157 , pp. 755-761
    • Iacobuzio-Donahue, C.A.1    Klimstra, D.S.2    Adsay, N.V.3
  • 7
    • 2442717796 scopus 로고    scopus 로고
    • Intraductal papillary mucinous neoplasms of the pancreas: An updated experience [discussion 797-9]
    • Sohn TA, Yeo CJ, Cameron JL, et al. Intraductal papillary mucinous neoplasms of the pancreas: an updated experience [discussion 797-9]. Ann Surg 2004;239:788-97.
    • (2004) Ann Surg , vol.239 , pp. 788-797
    • Sohn, T.A.1    Yeo, C.J.2    Cameron, J.L.3
  • 8
    • 18644383374 scopus 로고    scopus 로고
    • The dichotomy in the preinvasive neoplasia to invasive carcinoma sequence in the pancreas: Differential expression of MUC1 and MUC2 supports the existence of two separate pathways of carcinogenesis
    • Adsay NV, Merati K, Andea A, et al. The dichotomy in the preinvasive neoplasia to invasive carcinoma sequence in the pancreas: differential expression of MUC1 and MUC2 supports the existence of two separate pathways of carcinogenesis. Mod Pathol 2002;15:1087-95.
    • (2002) Mod Pathol , vol.15 , pp. 1087-1095
    • Adsay, N.V.1    Merati, K.2    Andea, A.3
  • 9
    • 0038779536 scopus 로고    scopus 로고
    • The "new kid on the block": Intraductal papillary mucinous neoplasms of the pancreas: Current concepts and controversies
    • Adsay NV. The "new kid on the block": Intraductal papillary mucinous neoplasms of the pancreas: current concepts and controversies. Surgery 2003;133:459-63.
    • (2003) Surgery , vol.133 , pp. 459-463
    • Adsay, N.V.1
  • 10
    • 11144356549 scopus 로고    scopus 로고
    • Main-duct intraductal papillary mucinous neoplasms of the pancreas: Clinical predictors of malignancy and long-term survival following resection
    • Salvia R, Fernandez-del Castillo C, Bassi C, et al. Main-duct intraductal papillary mucinous neoplasms of the pancreas: clinical predictors of malignancy and long-term survival following resection [discussion 685-7]. Ann Surg 2004;239:678-85.
    • (2004) Ann Surg , vol.239 , pp. 678-685
    • Salvia, R.1    Fernandez-del Castillo, C.2    Bassi, C.3
  • 11
    • 0034857973 scopus 로고    scopus 로고
    • Intraductal papillary mucinous neoplasms of the pancreas: An increasingly recognized clinicopathologic entity
    • Sohn TA, Yeo CJ, Cameron JL, Iacobuzio-Donahue CA, Hruban RH, Lillemoe KD. Intraductal papillary mucinous neoplasms of the pancreas: an increasingly recognized clinicopathologic entity [discussion 321-2]. Ann Surg 2001;234:313-21.
    • (2001) Ann Surg , vol.234 , pp. 313-321
    • Sohn, T.A.1    Yeo, C.J.2    Cameron, J.L.3    Iacobuzio-Donahue, C.A.4    Hruban, R.H.5    Lillemoe, K.D.6
  • 12
    • 0032897639 scopus 로고    scopus 로고
    • A clinicopathologic and immunohistochemical study of 22 intraductal papillary mucinous neoplasms of the pancreas, with a review of the literature
    • Paal E, Thompson LD, Przygodzki RM, Bratthauer GL, Heffess CS. A clinicopathologic and immunohistochemical study of 22 intraductal papillary mucinous neoplasms of the pancreas, with a review of the literature. Mod Pathol 1999;12:518-28.
    • (1999) Mod Pathol , vol.12 , pp. 518-528
    • Paal, E.1    Thompson, L.D.2    Przygodzki, R.M.3    Bratthauer, G.L.4    Heffess, C.S.5
  • 13
    • 0031459206 scopus 로고    scopus 로고
    • Prevalence of activating K-ras mutations in the evolutionary stages of neoplasia in intraductal papillary mucinous tumors of the pancreas
    • Z'Graggen K, Rivera JA, Compton CC, et al. Prevalence of activating K-ras mutations in the evolutionary stages of neoplasia in intraductal papillary mucinous tumors of the pancreas [discussion 498-500]. Ann Surg 1997;226:491-8.
    • (1997) Ann Surg , vol.226 , pp. 491-498
    • Z'Graggen, K.1    Rivera, J.A.2    Compton, C.C.3
  • 14
    • 0028597442 scopus 로고
    • Intraductal papillary-mucinous tumours represent a distinct group of pancreatic neoplasms: An investigation of tumour cell differentiation and K-ras, p53 and c-erbB-2 abnormalities in 26 patients
    • Sessa F, Solcia E, Capella C, et al. Intraductal papillary-mucinous tumours represent a distinct group of pancreatic neoplasms: an investigation of tumour cell differentiation and K-ras, p53 and c-erbB-2 abnormalities in 26 patients. Virchows Arch 1994;425:357-67.
    • (1994) Virchows Arch , vol.425 , pp. 357-367
    • Sessa, F.1    Solcia, E.2    Capella, C.3
  • 15
    • 0035184065 scopus 로고    scopus 로고
    • STK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreas
    • Sato N, Rosty C, Jansen M, et al. STK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreas. Am J Pathol 2001;159:2017-22.
    • (2001) Am J Pathol , vol.159 , pp. 2017-2022
    • Sato, N.1    Rosty, C.2    Jansen, M.3
  • 16
    • 0038107613 scopus 로고    scopus 로고
    • Loss of Stk11/Lkb1 expression in pancreatic and biliary neoplasms
    • Sahin F, Maitra A, Argani P, et al. Loss of Stk11/Lkb1 expression in pancreatic and biliary neoplasms. Mod Pathol 2003;16:686-91.
    • (2003) Mod Pathol , vol.16 , pp. 686-691
    • Sahin, F.1    Maitra, A.2    Argani, P.3
  • 17
    • 0030665130 scopus 로고    scopus 로고
    • Genetic progression and heterogeneity in intraductal papillary-mucinous neoplasms of the pancreas
    • Fujii H, Inagaki M, Kasai S, et al. Genetic progression and heterogeneity in intraductal papillary-mucinous neoplasms of the pancreas. Am J Pathol 1997;151:1447-54.
    • (1997) Am J Pathol , vol.151 , pp. 1447-1454
    • Fujii, H.1    Inagaki, M.2    Kasai, S.3
  • 18
    • 0036305839 scopus 로고    scopus 로고
    • Aberrant methylation of CpG islands in intraductal papillary mucinous neoplasms of the pancreas
    • Sato N, Ueki T, Fukushima N, et al. Aberrant methylation of CpG islands in intraductal papillary mucinous neoplasms of the pancreas. Gastroenterology 2002;123:365-72.
    • (2002) Gastroenterology , vol.123 , pp. 365-372
    • Sato, N.1    Ueki, T.2    Fukushima, N.3
  • 19
    • 0037328351 scopus 로고    scopus 로고
    • Molecular progression of promoter methylation in intraductal papillary mucinous neoplasms (IPMN) of the pancreas
    • House MG, Guo M, Iacobuzio-Donahue C, Herman JG. Molecular progression of promoter methylation in intraductal papillary mucinous neoplasms (IPMN) of the pancreas. Carcinogenesis 2003;24:193-8.
    • (2003) Carcinogenesis , vol.24 , pp. 193-198
    • House, M.G.1    Guo, M.2    Iacobuzio-Donahue, C.3    Herman, J.G.4
  • 20
    • 0036098611 scopus 로고    scopus 로고
    • Characterization of gene expression profiles in intraductal papillary-mucinous tumors of the pancreas
    • Terris B, Blaveri E, Crnogorac-Jurcevic T, et al. Characterization of gene expression profiles in intraductal papillary-mucinous tumors of the pancreas. Am J Pathol 2002;160:1745-54.
    • (2002) Am J Pathol , vol.160 , pp. 1745-1754
    • Terris, B.1    Blaveri, E.2    Crnogorac-Jurcevic, T.3
  • 21
    • 1242316269 scopus 로고    scopus 로고
    • Gene expression profiling identifies genes associated with invasive intraductal papillary mucinous neoplasms of the pancreas
    • Sato N, Fukushima N, Maitra A, et al. Gene expression profiling identifies genes associated with invasive intraductal papillary mucinous neoplasms of the pancreas. Am J Pathol 2004;164:903-14.
    • (2004) Am J Pathol , vol.164 , pp. 903-914
    • Sato, N.1    Fukushima, N.2    Maitra, A.3
  • 22
    • 0035190026 scopus 로고    scopus 로고
    • Cellular function of phosphoinositide 3-kinases: Implications for development, homeostasis, and cancer
    • Katso R, Okkenhaug K, Ahmadi K, White S, Timms J, Waterfield MD. Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer. Annu Rev Cell Dev Biol 2001;17:615-75.
    • (2001) Annu Rev Cell Dev Biol , vol.17 , pp. 615-675
    • Katso, R.1    Okkenhaug, K.2    Ahmadi, K.3    White, S.4    Timms, J.5    Waterfield, M.D.6
  • 23
    • 0030790548 scopus 로고    scopus 로고
    • Using structure to define the function of phosphoinositide 3-kinase family members
    • Domin J, Waterfield MD. Using structure to define the function of phosphoinositide 3-kinase family members. FEBS Lett 1997;410:91-5.
    • (1997) FEBS Lett , vol.410 , pp. 91-95
    • Domin, J.1    Waterfield, M.D.2
  • 24
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase AKT pathway in human cancer
    • Vivanco I, Sawyers CL. The phosphatidylinositol 3-kinase AKT pathway in human cancer. Nat Rev Cancer 2002;2:489-501.
    • (2002) Nat Rev Cancer , vol.2 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 26
    • 0032497832 scopus 로고    scopus 로고
    • Structure and function of phosphoinositide 3-kinases
    • Wymann MP, Pirola L. Structure and function of phosphoinositide 3-kinases. Biochim Biophys Acta 1998;1436:127-50.
    • (1998) Biochim Biophys Acta , vol.1436 , pp. 127-150
    • Wymann, M.P.1    Pirola, L.2
  • 27
    • 0033604577 scopus 로고    scopus 로고
    • Signaling by distinct classes of phosphoinositide 3-kinases
    • Vanhaesebroeck B, Waterfield MD. Signaling by distinct classes of phosphoinositide 3-kinases. Exp Cell Res 1999;253:239-54.
    • (1999) Exp Cell Res , vol.253 , pp. 239-254
    • Vanhaesebroeck, B.1    Waterfield, M.D.2
  • 30
    • 0026720350 scopus 로고
    • Phosphatidylinositol 3-kinase: Structure and expression of the 110 kd catalytic subunit
    • Hiles ID, Otsu M, Volinia S, et al. Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit. Cell 1992;70:419-29.
    • (1992) Cell , vol.70 , pp. 419-429
    • Hiles, I.D.1    Otsu, M.2    Volinia, S.3
  • 31
    • 0023897684 scopus 로고
    • Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate
    • Whitman M, Downes CP, Keeler M, Keller T, Cantley L. Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate. Nature 1988;332:644-6.
    • (1988) Nature , vol.332 , pp. 644-646
    • Whitman, M.1    Downes, C.P.2    Keeler, M.3    Keller, T.4    Cantley, L.5
  • 32
    • 0034653608 scopus 로고    scopus 로고
    • The PI3K-PDK1 connection: More than just a road to PKB
    • Vanhaesebroeck B, Alessi DR. The PI3K-PDK1 connection: more than just a road to PKB. Biochem J 2000;346 Pt 3:561-76.
    • (2000) Biochem J , vol.346 , Issue.PART 3 , pp. 561-576
    • Vanhaesebroeck, B.1    Alessi, D.R.2
  • 33
    • 11144358645 scopus 로고    scopus 로고
    • High frequency of mutations of the PIK3CA gene in human cancers
    • Samuels Y, Wang Z, Bardelli A, et al. High frequency of mutations of the PIK3CA gene in human cancers. Science 2004;304:554.
    • (2004) Science , vol.304 , pp. 554
    • Samuels, Y.1    Wang, Z.2    Bardelli, A.3
  • 34
    • 7444250290 scopus 로고    scopus 로고
    • Mutation of the PIK3CA gene in ovarian and breast cancer
    • Campbell IG, Russell SE, Choong DY, et al. Mutation of the PIK3CA gene in ovarian and breast cancer. Cancer Res 2004;64:7678-81.
    • (2004) Cancer Res , vol.64 , pp. 7678-7681
    • Campbell, I.G.1    Russell, S.E.2    Choong, D.Y.3
  • 35
    • 20044388328 scopus 로고    scopus 로고
    • PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas
    • Lee JW, Soung YH, Kim SY, et al. PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas. Oncogene 2005;24:1477-80.
    • (2005) Oncogene , vol.24 , pp. 1477-1480
    • Lee, J.W.1    Soung, Y.H.2    Kim, S.Y.3
  • 36
    • 3442878125 scopus 로고    scopus 로고
    • Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas
    • Broderick DK, Di C, Parrett TJ, et al. Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas. Cancer Res 2004;64:5048-50.
    • (2004) Cancer Res , vol.64 , pp. 5048-5050
    • Broderick, D.K.1    Di, C.2    Parrett, T.J.3
  • 37
    • 16644393213 scopus 로고    scopus 로고
    • The PIK3CA gene is mutated with high frequency in human breast cancers
    • Bachman KE, Argani P, Samuels Y, et al. The PIK3CA gene is mutated with high frequency in human breast cancers. Cancer Biol Ther 2004;3:772-5.
    • (2004) Cancer Biol Ther , vol.3 , pp. 772-775
    • Bachman, K.E.1    Argani, P.2    Samuels, Y.3
  • 38
    • 33645084781 scopus 로고    scopus 로고
    • PIK3CA mutations in head and neck squamous cell carcinoma
    • Qiu W, Schönleben F, Li X, et al. PIK3CA mutations in head and neck squamous cell carcinoma. Clin Cancer Res 2006;12:1441-6.
    • (2006) Clin Cancer Res , vol.12 , pp. 1441-1446
    • Qiu, W.1    Schönleben, F.2    Li, X.3
  • 39
    • 22144491262 scopus 로고    scopus 로고
    • Mutations of PIK3CA in gastric adenocarcinoma
    • Li VS, Wong CW, Chan TL, et al. Mutations of PIK3CA in gastric adenocarcinoma. BMC Cancer 2005;5:29.
    • (2005) BMC Cancer , vol.5 , pp. 29
    • Li, V.S.1    Wong, C.W.2    Chan, T.L.3
  • 40
    • 14144252004 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic
    • Kang S, Bader AG, Vogt PK. Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. Proc Natl Acad Sci U S A 2005;102:802-7.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 802-807
    • Kang, S.1    Bader, A.G.2    Vogt, P.K.3
  • 43
    • 33745729916 scopus 로고    scopus 로고
    • No mutations in PIK3CA identified in pancreatic carcinoma
    • Gallmeier E, Calhoun E, Kern SE. No mutations in PIK3CA identified in pancreatic carcinoma. NOGO 2004;8:2.
    • (2004) NOGO , vol.8 , pp. 2
    • Gallmeier, E.1    Calhoun, E.2    Kern, S.E.3
  • 44
    • 1842575443 scopus 로고    scopus 로고
    • Differential roles of alterations of p53, p16, and SMAD4 expression in the progression of intraductal papillary-mucinous tumors of the pancreas
    • Sasaki S, Yamamoto H, Kaneto H, et al. Differential roles of alterations of p53, p16, and SMAD4 expression in the progression of intraductal papillary-mucinous tumors of the pancreas. Oncol Rep 2003;10:21-5.
    • (2003) Oncol Rep , vol.10 , pp. 21-25
    • Sasaki, S.1    Yamamoto, H.2    Kaneto, H.3
  • 45
    • 0036110390 scopus 로고    scopus 로고
    • Aberrant p16(INK4A) and DPC4/Smad4 expression in intraductal papillary mucinous tumours of the pancreas is associated with invasive ductal adenocarcinoma
    • Biankin AV, Biankin SA, Kench JG, et al. Aberrant p16(INK4A) and DPC4/Smad4 expression in intraductal papillary mucinous tumours of the pancreas is associated with invasive ductal adenocarcinoma. Gut 2002;50:861-8.
    • (2002) Gut , vol.50 , pp. 861-868
    • Biankin, A.V.1    Biankin, S.A.2    Kench, J.G.3
  • 46
    • 0042575343 scopus 로고    scopus 로고
    • Aberrant methylation of suppressor of cytokine signalling-1 (SOCS-1) gene in pancreatic ductal neoplasms
    • Fukushima N, Sato N, Sahin F, Su GH, Hruban RH, Goggins M. Aberrant methylation of suppressor of cytokine signalling-1 (SOCS-1) gene in pancreatic ductal neoplasms. Br J Cancer 2003;89:338-43.
    • (2003) Br J Cancer , vol.89 , pp. 338-343
    • Fukushima, N.1    Sato, N.2    Sahin, F.3    Su, G.H.4    Hruban, R.H.5    Goggins, M.6
  • 47
    • 0037389979 scopus 로고    scopus 로고
    • Methylation of cyclin D2 is observed frequently in pancreatic cancer but is also an age-related phenomenon in gastrointestinal tissues
    • Matsubayashi H, Sato N, Fukushima N, et al. Methylation of cyclin D2 is observed frequently in pancreatic cancer but is also an age-related phenomenon in gastrointestinal tissues. Clin Cancer Res 2003;9:1446-52.
    • (2003) Clin Cancer Res , vol.9 , pp. 1446-1452
    • Matsubayashi, H.1    Sato, N.2    Fukushima, N.3
  • 48
    • 0032984141 scopus 로고    scopus 로고
    • Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers
    • Su GH, Hruban RH, Bansal RK, et al. Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers. Am J Pathol 1999;154:1835-40.
    • (1999) Am J Pathol , vol.154 , pp. 1835-1840
    • Su, G.H.1    Hruban, R.H.2    Bansal, R.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.