Novel selective inhibitors of the interaction of individual nuclear hormone receptors with a mutually shared steroid receptor coactivator 2

Journal of the American Chemical Society

Volumn 125, Issue 23, 2003, Pages 6852-6853

  Geistlinger, Timothy R ^a   Guy, R Kiplin ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; HORMONE RECEPTOR; NUCLEAR RECEPTOR COACTIVATOR 2; NUCLEIC ACID BINDING PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; BINDING COMPETITION; CRYSTAL STRUCTURE; HYDROPHOBICITY; MOLECULAR MIMICRY; PROTEIN PROTEIN INTERACTION; PROTEOMICS; SIGNAL TRANSDUCTION;

BIOMIMETIC MATERIALS; ESTROGEN RECEPTOR ALPHA; NUCLEAR RECEPTOR COACTIVATOR 2; PEPTIDES; RECEPTORS, ESTROGEN; RECEPTORS, THYROID HORMONE; THYROID HORMONE RECEPTORS BETA; TRANSCRIPTION FACTORS;

EID: 0037939789     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0348391     Document Type: Article

References (11)

1. Tsai, M. J.; O'Malley, B. W. Annu. Rev. Biochem. 1994, 63, 451-486. Aranda, A.; Pascual, A. Physiol. Rev. 2001, 81, 1269-1304.
2. Tsai, M. J.; O'Malley, B. W. Annu. Rev. Biochem. 1994, 63, 451-486. Aranda, A.; Pascual, A. Physiol. Rev. 2001, 81, 1269-1304.
3. McKenna, N. J.; O'Malley, B. W. Cell 2002, 108, 465-474;
4. Flygare, J. A.; Sutherlin, D. P.; Brown, S. D. Methods Mol. Biol. 2001, 176, 353-358.
5. Darimont, B. D.; Wagner, R. L.; Apriletti, J. W.; Stallcup, M. R.; Kushner, P. J.; Baxter, J. D.; Fletterick, R. J.; Yamamoto, K. R. Genes Dev. 1998, 12, 3343-3356.
6. Feng, W.; Ribeiro, R. C.; Wagner, R. L.; Nguyen, H.; Apriletti, J. W.; Fletterick, R. J.; Baxter, J. D.; Kushner, P. J.; West, B. L. Science 1998, 280, 1747-1749. Shiau, A. K.; Barstad, D.; Loria, P. M.; Cheng, L.; Kushner, P. J.; Agard, D. A.; Greene, G. L. Cell 1998, 95, 927-937.
7. Feng, W.; Ribeiro, R. C.; Wagner, R. L.; Nguyen, H.; Apriletti, J. W.; Fletterick, R. J.; Baxter, J. D.; Kushner, P. J.; West, B. L. Science 1998, 280, 1747-1749. Shiau, A. K.; Barstad, D.; Loria, P. M.; Cheng, L.; Kushner, P. J.; Agard, D. A.; Greene, G. L. Cell 1998, 95, 927-937.
8. Sun, Y.; Ewing, T. J.; Skillman, A. G.; Kuntz, I. D. J. Comput. Aided Mol. Des. 1998, 12, 597-604.
9. Geistlinger, T. R.; Guy, R. K. J. Am. Chem. Soc. 2001, 123, 1525-1526.
10. Chang, C.; Norris, J. D.; Gron, H.; Paige, L. A.; Hamilton, P. T.; Kenan, D. J.; Fowlkes, D.; McDonnell, D. P. Mol. Cell Biol. 1999, 19, 8226-8239. Northrop, J. P.; Nguyen, D.; Piplani, S.; Olivan, S. E.; Kwan, S. T.; Go, N. F.; Hart, C. P.; Schatz, P. J. Mol. Endocrinol. 2000, 14, 605-622.
11. Chang, C.; Norris, J. D.; Gron, H.; Paige, L. A.; Hamilton, P. T.; Kenan, D. J.; Fowlkes, D.; McDonnell, D. P. Mol. Cell Biol. 1999, 19, 8226-8239. Northrop, J. P.; Nguyen, D.; Piplani, S.; Olivan, S. E.; Kwan, S. T.; Go, N. F.; Hart, C. P.; Schatz, P. J. Mol. Endocrinol. 2000, 14, 605-622.