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Volumn 27, Issue 7, 2006, Pages 1358-1368

Enhanced tumorigenesis in p53 knockout mice exposed in utero to high-dose vitamin E

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; PROTEIN P53; REACTIVE OXYGEN METABOLITE;

EID: 33745598549     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgi325     Document Type: Article
Times cited : (19)

References (94)
  • 1
    • 0035906343 scopus 로고    scopus 로고
    • DNA damage from micronutrient deficiencies is likely to be a major cause of cancer
    • Ames,B.N. (2001) DNA damage from micronutrient deficiencies is likely to be a major cause of cancer. Mutat Res., 475, 7-20.
    • (2001) Mutat Res. , vol.475 , pp. 7-20
    • Ames, B.N.1
  • 2
    • 0034470219 scopus 로고    scopus 로고
    • Oxidative DNA damage: Endogenous and chemically induced
    • Williams,G.M. and Jeffrey,A.M. (2000) Oxidative DNA damage: Endogenous and chemically induced. Regul. Toxicol. Pharmacol., 32, 283-292.
    • (2000) Regul. Toxicol. Pharmacol. , vol.32 , pp. 283-292
    • Williams, G.M.1    Jeffrey, A.M.2
  • 3
    • 0029968112 scopus 로고    scopus 로고
    • Biochemical toxicology of chemical teratogenesis
    • Wells,P.G. and Winn,L.M. (1996) Biochemical toxicology of chemical teratogenesis. Crit. Rev. Biochem. Mol. Biol., 31, 1-40.
    • (1996) Crit. Rev. Biochem. Mol. Biol. , vol.31 , pp. 1-40
    • Wells, P.G.1    Winn, L.M.2
  • 5
    • 0034796353 scopus 로고    scopus 로고
    • Role of free radicals in the neurodegenerative diseases: Therapeutic implications for antioxidant treatment
    • Halliwell,B. (2001) Role of free radicals in the neurodegenerative diseases: Therapeutic implications for antioxidant treatment. Drugs Aging, 18, 685-716.
    • (2001) Drugs Aging , vol.18 , pp. 685-716
    • Halliwell, B.1
  • 7
    • 1542287559 scopus 로고    scopus 로고
    • Redox control of signal transduction, gene expression and cellular senescence
    • Esposito,F., Ammendola,R., Faraonio,R., Russo,T. and Cimino,F. (2004) Redox control of signal transduction, gene expression and cellular senescence. Neurochem. Res., 29, 617-28.
    • (2004) Neurochem. Res. , vol.29 , pp. 617-628
    • Esposito, F.1    Ammendola, R.2    Faraonio, R.3    Russo, T.4    Cimino, F.5
  • 8
    • 0036015521 scopus 로고    scopus 로고
    • Reactive oxygen species as double-edged swords in cellular processes: Low-dose cell signaling versus high-dose toxicity
    • Martin,K.R. and Barrett,J.C. (2002) Reactive oxygen species as double-edged swords in cellular processes: Low-dose cell signaling versus high-dose toxicity. Hum. Exp. Toxicol., 21, 71-5.
    • (2002) Hum. Exp. Toxicol. , vol.21 , pp. 71-75
    • Martin, K.R.1    Barrett, J.C.2
  • 9
    • 0242608621 scopus 로고    scopus 로고
    • Pathways of oxidative damage
    • Imlay,J.A. (2003) Pathways of oxidative damage. Annu. Rev. Microbiol., 57, 395-418.
    • (2003) Annu. Rev. Microbiol. , vol.57 , pp. 395-418
    • Imlay, J.A.1
  • 10
    • 0025045198 scopus 로고
    • The role of 8-hydroxyguanine in carcinogenesis
    • Floyd,R.A. (1990) The role of 8-hydroxyguanine in carcinogenesis. Carcinogenesis, 11, 1447-1450.
    • (1990) Carcinogenesis , vol.11 , pp. 1447-1450
    • Floyd, R.A.1
  • 11
    • 0023647116 scopus 로고
    • Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues
    • Kuchino,Y., Mori,F., Kasai,H., Inoue,H., Iwai,S., Miura,K., Ohtsuka,E. and Nishimura,S. (1987) Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues. Nature, 327, 77-79.
    • (1987) Nature , vol.327 , pp. 77-79
    • Kuchino, Y.1    Mori, F.2    Kasai, H.3    Inoue, H.4    Iwai, S.5    Miura, K.6    Ohtsuka, E.7    Nishimura, S.8
  • 12
    • 0034924860 scopus 로고    scopus 로고
    • Vitamins C and E: Missing links in preventing preterm premature rupture of membranes?
    • Woods,J.R.,Jr, Plessinger,M.A. and Miller,R.K. (2001) Vitamins C and E: missing links in preventing preterm premature rupture of membranes?. Am. J. Obstet. Gynecol., 185, 5-10.
    • (2001) Am. J. Obstet. Gynecol. , vol.185 , pp. 5-10
    • Woods Jr., J.R.1    Plessinger, M.A.2    Miller, R.K.3
  • 13
    • 0037633881 scopus 로고    scopus 로고
    • Developmental changes in murine brain antioxidant enzymes
    • Khan,J.Y. and Black,S.M. (2003) Developmental changes in murine brain antioxidant enzymes. Pediat. Res., 54, 77-82.
    • (2003) Pediat. Res. , vol.54 , pp. 77-82
    • Khan, J.Y.1    Black, S.M.2
  • 14
    • 0032899624 scopus 로고    scopus 로고
    • Maternal administration of superoxide dismutase and catalase in phenytoin teratogenicity
    • Winn,L.M. and Wells,P.G. (1999) Maternal administration of superoxide dismutase and catalase in phenytoin teratogenicity. Free Radic. Biol. Med., 26, 266-274.
    • (1999) Free Radic. Biol. Med. , vol.26 , pp. 266-274
    • Winn, L.M.1    Wells, P.G.2
  • 15
    • 0025352048 scopus 로고
    • Temporal expression of genes encoding free radical-metabolizing enzymes is associated with higher mRNA levels during in utero development in mice
    • el-Hage,S. and Singh,S.M. (1990) Temporal expression of genes encoding free radical-metabolizing enzymes is associated with higher mRNA levels during in utero development in mice. Dev. Genet., 11, 149-159.
    • (1990) Dev. Genet. , vol.11 , pp. 149-159
    • el-Hage, S.1    Singh, S.M.2
  • 16
    • 0026012516 scopus 로고
    • Glutathione and related enzyme activity in the 11-day rat embryo, placenta and perinatal rat liver
    • Serafini,M.T., Arola,L. and Romeu,A. (1991) Glutathione and related enzyme activity in the 11-day rat embryo, placenta and perinatal rat liver. Biol. Neonate, 60, 236-242.
    • (1991) Biol. Neonate , vol.60 , pp. 236-242
    • Serafini, M.T.1    Arola, L.2    Romeu, A.3
  • 17
    • 0033977661 scopus 로고    scopus 로고
    • An embryoprotective role for glucose-6-phosphate dehydrogenase in developmental oxidative stress and chemical teratogenesis
    • Nicol,C.J., Zielenski,J., Tsui,L.C. and Wells,P.G. (2000) An embryoprotective role for glucose-6-phosphate dehydrogenase in developmental oxidative stress and chemical teratogenesis. FASEB J., 14, 111-127.
    • (2000) FASEB J. , vol.14 , pp. 111-127
    • Nicol, C.J.1    Zielenski, J.2    Tsui, L.C.3    Wells, P.G.4
  • 18
    • 4143134320 scopus 로고    scopus 로고
    • Introduction and overview. Perinatal carcinogenesis: Growing a node for epidemiology, risk management, and animal studies
    • Anderson,L.M. (2004) Introduction and overview. Perinatal carcinogenesis: Growing a node for epidemiology, risk management, and animal studies. Toxicol. Appl. Pharmacol., 199, 85-90.
    • (2004) Toxicol. Appl. Pharmacol. , vol.199 , pp. 85-90
    • Anderson, L.M.1
  • 22
    • 0029006469 scopus 로고
    • A teratologic suppressor role for p53 in benzo[a]pyrene-treated transgenic p53-deficient mice
    • Nicol,C.J., Harrison,M.L., Laposa,R.R., Gimelshtein,I.L. and Wells,P.G. (1995) A teratologic suppressor role for p53 in benzo[a]pyrene-treated transgenic p53-deficient mice. Nat. Genet., 10, 181-187.
    • (1995) Nat. Genet. , vol.10 , pp. 181-187
    • Nicol, C.J.1    Harrison, M.L.2    Laposa, R.R.3    Gimelshtein, I.L.4    Wells, P.G.5
  • 23
    • 0011829739 scopus 로고    scopus 로고
    • p53 modulation of phenyotoin embryopathies in p53 knockout mice
    • (No. 1502, Abstract)
    • Wong,A. and Wells,P.G. (2002) p53 modulation of phenyotoin embryopathies in p53 knockout mice. Toxicol. Sci. (Suppl.: The Toxicologist), 66, 306-307, (No. 1502, Abstract).
    • (2002) Toxicol. Sci. (Suppl.: The Toxicologist) , vol.66 , pp. 306-307
    • Wong, A.1    Wells, P.G.2
  • 24
    • 0030988703 scopus 로고    scopus 로고
    • Vitamin E decreases the occurrence of malformations in the offspring of diabetic rats
    • Siman,C.M. and Eriksson,U.J. (1997) Vitamin E decreases the occurrence of malformations in the offspring of diabetic rats. Diabetes, 46, 1054-1061.
    • (1997) Diabetes , vol.46 , pp. 1054-1061
    • Siman, C.M.1    Eriksson, U.J.2
  • 25
    • 2442639924 scopus 로고
    • Reduction in phenytoin teratogenicity by pretreatment with the antioxidant d-alpha-tocopherol acetate (vitamin E) in CD-1 mice
    • Abstract
    • Sanyal,S. and Wells,PG (1993) Reduction in phenytoin teratogenicity by pretreatment with the antioxidant d-alpha-tocopherol acetate (vitamin E) in CD-1 mice. Toxicologist, 13, 252, Abstract.
    • (1993) Toxicologist , vol.13 , pp. 252
    • Sanyal, S.1    Wells, P.G.2
  • 26
    • 0033914008 scopus 로고    scopus 로고
    • Role of vitamins C and E as chemopreventive agents in the hamster cheek pouch treated with the oral carcinogen-DMBA
    • Sawant,S.S. and Kandarkar,S.V. (2000) Role of vitamins C and E as chemopreventive agents in the hamster cheek pouch treated with the oral carcinogen-DMBA. Oral. Dis., 6, 241-247.
    • (2000) Oral. Dis. , vol.6 , pp. 241-247
    • Sawant, S.S.1    Kandarkar, S.V.2
  • 27
    • 0033397377 scopus 로고    scopus 로고
    • Mechanisms of cancer chemo-prevention in hepatic carcinogenesis: Modulation of focal lesion growth in mice
    • Klaunig,J.E. and Kamendulis,L.M. (1999) Mechanisms of cancer chemo-prevention in hepatic carcinogenesis: Modulation of focal lesion growth in mice. Toxicol. Sci., 52, 101-106.
    • (1999) Toxicol. Sci. , vol.52 , pp. 101-106
    • Klaunig, J.E.1    Kamendulis, L.M.2
  • 28
    • 0026615990 scopus 로고
    • Vitamin E and cancer prevention: Recent advances and future potentials
    • Prasad,K.N. and Edwards-Prasad,J. (1992) Vitamin E and cancer prevention: Recent advances and future potentials. J. Am. Coll. Nutr., 11, 487-500.
    • (1992) J. Am. Coll. Nutr. , vol.11 , pp. 487-500
    • Prasad, K.N.1    Edwards-Prasad, J.2
  • 31
    • 0041767335 scopus 로고    scopus 로고
    • Vitamin E and its role in the prevention of atherosclerosis and carcinogenesis: A review
    • Dutta,A. and Dutta,S.K. (2003) Vitamin E and its role in the prevention of atherosclerosis and carcinogenesis: A review. J. Am. Coll. Nutr., 22, 258-268.
    • (2003) J. Am. Coll. Nutr. , vol.22 , pp. 258-268
    • Dutta, A.1    Dutta, S.K.2
  • 32
    • 0035159165 scopus 로고    scopus 로고
    • Vitamin E: Protective role of a Janus molecule
    • Ricciarelli,R., Zingg,J.M. and Azzi,A. (2001) Vitamin E: Protective role of a Janus molecule. FASEB J., 15, 2314-2325.
    • (2001) FASEB J. , vol.15 , pp. 2314-2325
    • Ricciarelli, R.1    Zingg, J.M.2    Azzi, A.3
  • 33
    • 0038116394 scopus 로고    scopus 로고
    • Incidence of cancer and mortality following alpha-tocopherol and beta-carotene supplementation: A postintervention follow-up
    • Virtamo,J., Pietinen,P., Huttunen,J.K., Korhonen,P., Malila,N., Virtanen,M.J., Albanes,D., Taylor,P.R. and Albert,P. (2003) Incidence of cancer and mortality following alpha-tocopherol and beta-carotene supplementation: A postintervention follow-up. JAMA, 290, 476-485.
    • (2003) JAMA , vol.290 , pp. 476-485
    • Virtamo, J.1    Pietinen, P.2    Huttunen, J.K.3    Korhonen, P.4    Malila, N.5    Virtanen, M.J.6    Albanes, D.7    Taylor, P.R.8    Albert, P.9
  • 34
    • 0029868539 scopus 로고    scopus 로고
    • The dual roles of nutrients as antioxidants and prooxidants: Their effects on tumor cell growth
    • Schwartz,J.L. (1996) The dual roles of nutrients as antioxidants and prooxidants: Their effects on tumor cell growth. J. Nutr., 126, 1221S-1227S.
    • (1996) J. Nutr. , vol.126
    • Schwartz, J.L.1
  • 35
    • 0036244669 scopus 로고    scopus 로고
    • The 80th anniversary of vitamin E: Beyond its antioxidant properties
    • Ricciarelli,R., Zingg,J.M. and Azzi,A. (2002) The 80th anniversary of vitamin E: Beyond its antioxidant properties. Biol. Chem., 383, 457-465.
    • (2002) Biol. Chem. , vol.383 , pp. 457-465
    • Ricciarelli, R.1    Zingg, J.M.2    Azzi, A.3
  • 37
    • 0027386275 scopus 로고
    • Vitamins regulate gene expression and induce differentiation and growth inhibition in cancer cells. Their relevance in cancer prevention
    • Prasad,K.N., Edwards-Prasad,J., Kumar,S. and Meyers,A. (1993) Vitamins regulate gene expression and induce differentiation and growth inhibition in cancer cells. Their relevance in cancer prevention. Arch. Otolaryngol. Head Neck Surg., 119, 1133-1140.
    • (1993) Arch. Otolaryngol. Head Neck Surg. , vol.119 , pp. 1133-1140
    • Prasad, K.N.1    Edwards-Prasad, J.2    Kumar, S.3    Meyers, A.4
  • 38
    • 3142707998 scopus 로고    scopus 로고
    • The role of alpha-tocopherol in preventing disease
    • Azzi,A. (2004) The role of alpha-tocopherol in preventing disease. Eur. J. Nutr., 43 (Suppl. 1), I18-I25.
    • (2004) Eur. J. Nutr. , vol.43 , Issue.SUPPL. 1
    • Azzi, A.1
  • 39
    • 14944379531 scopus 로고    scopus 로고
    • Effect of dietary vitamin E on endogenous and phenytoin-initiated embryonic DNA oxidation
    • (No. 234, Abstract)
    • Chen,C.S. and Wells,P.G. (2001) Effect of dietary vitamin E on endogenous and phenytoin-initiated embryonic DNA oxidation. Toxicol. Sci. (Suppl.: The Toxicologist), 60, 48, (No. 234, Abstract).
    • (2001) Toxicol. Sci. (Suppl.: The Toxicologist) , vol.60 , pp. 48
    • Chen, C.S.1    Wells, P.G.2
  • 40
    • 0021342507 scopus 로고
    • Formation and removal of DNA adducts in rat liver treated with N-hydroxy derivatives of 2-acetylaminofluorene, 4-acetylaminobiphenyl, and 2-acetylaminophenanthrene
    • Gupta,R.C. and Dighe,N.R. (1984) Formation and removal of DNA adducts in rat liver treated with N-hydroxy derivatives of 2-acetylaminofluorene, 4-acetylaminobiphenyl, and 2-acetylaminophenanthrene. Carcinogenesis, 5, 343-349.
    • (1984) Carcinogenesis , vol.5 , pp. 343-349
    • Gupta, R.C.1    Dighe, N.R.2
  • 41
    • 0032566524 scopus 로고    scopus 로고
    • Free radical intermediates of phenytoin and related teratogens. Prostaglandin H synthase-catalyzed bioactivation, electron paramagnetic resonance spectrometry, and photochemical product analysis
    • Parman,T., Chen,G. and Wells,P.G. (1998) Free radical intermediates of phenytoin and related teratogens. Prostaglandin H synthase-catalyzed bioactivation, electron paramagnetic resonance spectrometry, and photochemical product analysis. J. Biol. Chem., 273, 25079-25088.
    • (1998) J. Biol. Chem. , vol.273 , pp. 25079-25088
    • Parman, T.1    Chen, G.2    Wells, P.G.3
  • 42
    • 0038799736 scopus 로고    scopus 로고
    • Oxidative DNA damage: Mechanisms, mutation, and disease
    • Cooke,M.S., Evans,M.D., Dizdaroglu,M. and Lunec,J. (2003) Oxidative DNA damage: Mechanisms, mutation, and disease. FASEB J., 17, 1195-1214.
    • (2003) FASEB J. , vol.17 , pp. 1195-1214
    • Cooke, M.S.1    Evans, M.D.2    Dizdaroglu, M.3    Lunec, J.4
  • 43
    • 0029886786 scopus 로고    scopus 로고
    • Cancer risk and oxidative DNA damage in man
    • Loft,S. and Poulsen,H.E. (1996) Cancer risk and oxidative DNA damage in man. J. Mol. Med., 74, 297-312.
    • (1996) J. Mol. Med. , vol.74 , pp. 297-312
    • Loft, S.1    Poulsen, H.E.2
  • 44
    • 0032565577 scopus 로고    scopus 로고
    • Mutagenicity and repair of oxidative DNA damage: Insights from studies using defined lesions
    • Wang,D., Kreutzer,D.A. and Essigmann,J.M. (1998) Mutagenicity and repair of oxidative DNA damage: Insights from studies using defined lesions. Mutat Res., 400, 99-115.
    • (1998) Mutat Res. , vol.400 , pp. 99-115
    • Wang, D.1    Kreutzer, D.A.2    Essigmann, J.M.3
  • 45
    • 0035109131 scopus 로고    scopus 로고
    • Nutritional status of vitamin A, E, C, B1, B2, B6, nicotinic acid, B12, folate, and beta-carotene in young women
    • Hiraoka,M. (2001) Nutritional status of vitamin A, E, C, B1, B2, B6, nicotinic acid, B12, folate, and beta-carotene in young women. J. Nutr. Sci. Vitaminol. (Tokyo), 47, 20-27.
    • (2001) J. Nutr. Sci. Vitaminol. (Tokyo) , vol.47 , pp. 20-27
    • Hiraoka, M.1
  • 46
    • 0034988072 scopus 로고    scopus 로고
    • Vitamin E: Too much or not enough?
    • Traber,M.G. (2001) Vitamin E: Too much or not enough? Am. J. Clin. Nutr., 73, 997-998.
    • (2001) Am. J. Clin. Nutr. , vol.73 , pp. 997-998
    • Traber, M.G.1
  • 47
    • 0032439246 scopus 로고    scopus 로고
    • Nutrition, cancer, and aging
    • Dreosti,I.E. (1998) Nutrition, cancer, and aging. Ann. NY Acad. Sci., 854, 371-377.
    • (1998) Ann. NY Acad. Sci. , vol.854 , pp. 371-377
    • Dreosti, I.E.1
  • 50
    • 0030727705 scopus 로고    scopus 로고
    • Dietary restriction reduces insulin-like growth factor I levels, which modulates apoptosis, cell proliferation, and tumor progression in p53-deficient mice
    • Dunn,S.E., Kari,F.W., French,J., Leininger,J.R., Travlos,G., Wilson,R. and Barrett,J.C. (1997) Dietary restriction reduces insulin-like growth factor I levels, which modulates apoptosis, cell proliferation, and tumor progression in p53-deficient mice. Cancer Res., 57, 4667-4672.
    • (1997) Cancer Res. , vol.57 , pp. 4667-4672
    • Dunn, S.E.1    Kari, F.W.2    French, J.3    Leininger, J.R.4    Travlos, G.5    Wilson, R.6    Barrett, J.C.7
  • 51
    • 0027191495 scopus 로고
    • Effects of caloric restriction and dietary fat on epithelial cell proliferation in rat colon
    • Steinbach,G., Kumar,S.P., Reddy,B.S., Lipkin,M. and Holt,P.R. (1993) Effects of caloric restriction and dietary fat on epithelial cell proliferation in rat colon. Cancer Res., 53, 2745-2749.
    • (1993) Cancer Res. , vol.53 , pp. 2745-2749
    • Steinbach, G.1    Kumar, S.P.2    Reddy, B.S.3    Lipkin, M.4    Holt, P.R.5
  • 52
    • 0035266244 scopus 로고    scopus 로고
    • Modulation of experimental colon tumorigenesis by types and amounts of dietary fatty acids
    • Rao,C.V., Hirose,Y., Indranie,C. and Reddy,B.S. (2001) Modulation of experimental colon tumorigenesis by types and amounts of dietary fatty acids. Cancer Res., 61, 1927-1933.
    • (2001) Cancer Res. , vol.61 , pp. 1927-1933
    • Rao, C.V.1    Hirose, Y.2    Indranie, C.3    Reddy, B.S.4
  • 53
    • 0025062101 scopus 로고
    • Nutrition and breast cancer
    • Kritchevsky,D. (1990) Nutrition and breast cancer. Cancer, 66, 1321-1325.
    • (1990) Cancer , vol.66 , pp. 1321-1325
    • Kritchevsky, D.1
  • 54
    • 0034026974 scopus 로고    scopus 로고
    • Relationship between vitamin E requirement and polyunsaturated fatty acid intake in man: A review
    • Valk,E.E. and Hornstra,G. (2000) Relationship between vitamin E requirement and polyunsaturated fatty acid intake in man: A review. Int. J. Vitam. Nutr. Res., 70, 31-42.
    • (2000) Int. J. Vitam. Nutr. Res. , vol.70 , pp. 31-42
    • Valk, E.E.1    Hornstra, G.2
  • 56
    • 0033941397 scopus 로고    scopus 로고
    • Critical windows of exposure for children's health: Cancer in human epidemiological studies and neoplasms in experimental animal models
    • Anderson,L.M., Diwan,B.A., Fear,N.T. and Roman,E. (2000) Critical windows of exposure for children's health: Cancer in human epidemiological studies and neoplasms in experimental animal models. Environ. Health Perspect., 108 (Suppl. 3), 573-594.
    • (2000) Environ. Health Perspect. , vol.108 , Issue.SUPPL. 3 , pp. 573-594
    • Anderson, L.M.1    Diwan, B.A.2    Fear, N.T.3    Roman, E.4
  • 57
    • 0037202623 scopus 로고    scopus 로고
    • DNA repair during organogenesis
    • Vinson,R.K. and Hales,B.F. (2002) DNA repair during organogenesis. Mutat. Res., 509, 79-91.
    • (2002) Mutat. Res. , vol.509 , pp. 79-91
    • Vinson, R.K.1    Hales, B.F.2
  • 58
    • 74049154676 scopus 로고    scopus 로고
    • Enhanced phenytoin embryopathy in p53-deficient mice: Characterisation of embryonic p53 genotype and the p53, p21 and bax DNA damage response proteins
    • (No. 997, Abstract)
    • Laposa,R.R., Chan,K., Wiley,M.J. and Wells,P.G. (1996) Enhanced phenytoin embryopathy in p53-deficient mice: Characterisation of embryonic p53 genotype and the p53, p21 and bax DNA damage response proteins. Fundam. Appl. Toxicol. (Suppl.: The Toxicologist), 30, 195, (No. 997, Abstract).
    • (1996) Fundam. Appl. Toxicol. (Suppl.: The Toxicologist) , vol.30 , pp. 195
    • Laposa, R.R.1    Chan, K.2    Wiley, M.J.3    Wells, P.G.4
  • 59
    • 0029049046 scopus 로고
    • Phenytoin-initiated DNA oxidation in murine embryo culture, and embryo protection by the antioxidative enzymes superoxide dismutase and catalase: Evidence for reactive oxygen species-mediated DNA oxidation in the molecular mechanism of phenytoin teratogenicity
    • Winn,L.M. and Wells,P.G. (1995) Phenytoin-initiated DNA oxidation in murine embryo culture, and embryo protection by the antioxidative enzymes superoxide dismutase and catalase: Evidence for reactive oxygen species-mediated DNA oxidation in the molecular mechanism of phenytoin teratogenicity. Mol. Pharmacol., 48, 112-120.
    • (1995) Mol. Pharmacol. , vol.48 , pp. 112-120
    • Winn, L.M.1    Wells, P.G.2
  • 60
    • 0033027549 scopus 로고    scopus 로고
    • p53 in embryonic development: Maintaining a fine balance
    • Choi,J. and Donehower,L.A. (1999) p53 in embryonic development: maintaining a fine balance. Cell. Mol. Life Sci., 55, 38-47.
    • (1999) Cell. Mol. Life Sci. , vol.55 , pp. 38-47
    • Choi, J.1    Donehower, L.A.2
  • 62
    • 0023749362 scopus 로고
    • The phosphoprotein p53 is down-regulated post-transcriptionally during embryogenesis in vertebrates
    • Louis,J.M., McFarland,V.W., May,P. and Mora,P.T. (1988) The phosphoprotein p53 is down-regulated post-transcriptionally during embryogenesis in vertebrates. Biochim. Biophys. Acta., 950, 395-402.
    • (1988) Biochim. Biophys. Acta. , vol.950 , pp. 395-402
    • Louis, J.M.1    McFarland, V.W.2    May, P.3    Mora, P.T.4
  • 64
    • 0035874967 scopus 로고    scopus 로고
    • Vitamin C-induced decomposition of lipid hydroperoxides to endogenous genotoxins
    • Lee,S.H., Oe,T. and Blair,I.A. (2001) Vitamin C-induced decomposition of lipid hydroperoxides to endogenous genotoxins. Science, 292, 2083-2086.
    • (2001) Science , vol.292 , pp. 2083-2086
    • Lee, S.H.1    Oe, T.2    Blair, I.A.3
  • 66
    • 0035991240 scopus 로고    scopus 로고
    • Signaling and proapoptotic functions of transformed cell-derived reactive oxygen species
    • Bauer,G. (2002) Signaling and proapoptotic functions of transformed cell-derived reactive oxygen species. Prostag. Leukot Essent. Fatty Acids, 66, 41-56.
    • (2002) Prostag. Leukot Essent. Fatty Acids , vol.66 , pp. 41-56
    • Bauer, G.1
  • 67
    • 0034991034 scopus 로고    scopus 로고
    • Signalling apoptosis: A radical approach
    • Carmody,R.J. and Cotter,T.G. (2001) Signalling apoptosis: A radical approach. Redox Rep., 6, 77-90.
    • (2001) Redox Rep. , vol.6 , pp. 77-90
    • Carmody, R.J.1    Cotter, T.G.2
  • 68
    • 0036829062 scopus 로고    scopus 로고
    • Antioxidant and prooxidant mechanisms in the regulation of redox(y)-sensitive transcription factors
    • Haddad,J.J. (2002) Antioxidant and prooxidant mechanisms in the regulation of redox(y)-sensitive transcription factors. Cell Signal, 14, 879-897.
    • (2002) Cell Signal , vol.14 , pp. 879-897
    • Haddad, J.J.1
  • 69
    • 0036021828 scopus 로고    scopus 로고
    • Oxygen-sensitive pro-inflammatory cytokines, apoptosis signaling and redox-responsive transcription factors in development and pathophysiology
    • Haddad,J.J. (2002) Oxygen-sensitive pro-inflammatory cytokines, apoptosis signaling and redox-responsive transcription factors in development and pathophysiology. Cytokines Cell Mol. Ther., 7, 1-14.
    • (2002) Cytokines Cell Mol. Ther. , vol.7 , pp. 1-14
    • Haddad, J.J.1
  • 70
    • 0037194596 scopus 로고    scopus 로고
    • Proapoptotic and redox state-related signaling of reactive oxygen species generated by transformed fibroblasts
    • Schimmel,M. and Bauer,G. (2002) Proapoptotic and redox state-related signaling of reactive oxygen species generated by transformed fibroblasts. Oncogene, 21, 5886-5896.
    • (2002) Oncogene , vol.21 , pp. 5886-5896
    • Schimmel, M.1    Bauer, G.2
  • 72
    • 0034597750 scopus 로고    scopus 로고
    • Cytochrome P4503A-dependent metabolism of tocopherols and inhibition by sesamin
    • Parker,R.S., Sontag,T.J. and Swanson,J.E. (2000) Cytochrome P4503A-dependent metabolism of tocopherols and inhibition by sesamin. Biochem. Biophys. Res. Commun., 277, 531-534.
    • (2000) Biochem. Biophys. Res. Commun. , vol.277 , pp. 531-534
    • Parker, R.S.1    Sontag, T.J.2    Swanson, J.E.3
  • 73
    • 0037067711 scopus 로고    scopus 로고
    • Cytochrome P450 omega-hydroxylase pathway of tocopherol catabolism. Novel mechanism of regulation of vitamin E status
    • Sontag,T.J. and Parker,R.S. (2002) Cytochrome P450 omega-hydroxylase pathway of tocopherol catabolism. Novel mechanism of regulation of vitamin E status. J. Biol. Chem., 277, 25290-25296.
    • (2002) J. Biol. Chem. , vol.277 , pp. 25290-25296
    • Sontag, T.J.1    Parker, R.S.2
  • 74
    • 0033037413 scopus 로고    scopus 로고
    • Vitamin E: Function and metabolism
    • Brigelius-Flohe,R. and Traber,M.G. (1999) Vitamin E: Function and metabolism. FASEB J., 13, 1145-1155.
    • (1999) FASEB J. , vol.13 , pp. 1145-1155
    • Brigelius-Flohe, R.1    Traber, M.G.2
  • 75
    • 0033571604 scopus 로고    scopus 로고
    • Quantification of the alpha- and gamma-tocopherol metabolites 2,5,7, 8-tetramethyl-2-(2′-carboxyethyl)-6-hydroxychroman and 2,7, 8-trimethyl-2-(2′-carboxyethyl)-6-hydroxychroman in human serum
    • Stahl,W., Graf,P., Brigelius-Flohe,R., Wechter,W. and Sies,H. (1999) Quantification of the alpha- and gamma-tocopherol metabolites 2,5,7, 8-tetramethyl-2-(2′-carboxyethyl)-6-hydroxychroman and 2,7, 8-trimethyl-2-(2′-carboxyethyl)-6-hydroxychroman in human serum. Anal. Biochem., 275, 254-259.
    • (1999) Anal. Biochem. , vol.275 , pp. 254-259
    • Stahl, W.1    Graf, P.2    Brigelius-Flohe, R.3    Wechter, W.4    Sies, H.5
  • 76
    • 0035879776 scopus 로고    scopus 로고
    • Tocopherols are metabolized in HepG2 cells by side chain omega-oxidation and consecutive beta-oxidation
    • Birringer,M., Drogan,D. and Brigelius-Flohe,R. (2001) Tocopherols are metabolized in HepG2 cells by side chain omega-oxidation and consecutive beta-oxidation. Free Radic. Biol. Med., 31, 226-232.
    • (2001) Free Radic. Biol. Med. , vol.31 , pp. 226-232
    • Birringer, M.1    Drogan, D.2    Brigelius-Flohe, R.3
  • 77
    • 0036245234 scopus 로고    scopus 로고
    • Dietary sesame seed and its lignans inhibit 2,7,8-trimethyl- 2(2′-carboxyethyl)-6-hydroxychroman excretion into urine of rats fed gamma-tocopherol
    • Ikeda,S., Tohyama,T. and Yamashita,K. (2002) Dietary sesame seed and its lignans inhibit 2,7,8-trimethyl- 2(2′-carboxyethyl -6-hydroxychroman excretion into urine of rats fed gamma-tocopherol. J. Nutr., 132, 961-966.
    • (2002) J. Nutr. , vol.132 , pp. 961-966
    • Ikeda, S.1    Tohyama, T.2    Yamashita, K.3
  • 79
    • 0032169485 scopus 로고    scopus 로고
    • The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions
    • Lehmann,J.M., McKee,D.D., Watson,M.A., Willson,T.M., Moore,J.T. and Kliewer,S.A. (1998) The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. J. Clin. Invest., 102, 1016-1023.
    • (1998) J. Clin. Invest. , vol.102 , pp. 1016-1023
    • Lehmann, J.M.1    McKee, D.D.2    Watson, M.A.3    Willson, T.M.4    Moore, J.T.5    Kliewer, S.A.6
  • 80
    • 0036799870 scopus 로고    scopus 로고
    • The nuclear pregnane X receptor: A key regulator of xenobiotic metabolism
    • Kliewer,S.A., Goodwin,B. and Willson,T.M. (2002) The nuclear pregnane X receptor: A key regulator of xenobiotic metabolism. Endocr. Rev., 23, 687-702.
    • (2002) Endocr. Rev. , vol.23 , pp. 687-702
    • Kliewer, S.A.1    Goodwin, B.2    Willson, T.M.3
  • 81
    • 1342338269 scopus 로고    scopus 로고
    • Profiling of genes differentially expressed between fetal liver and postnatal liver using high-density oligonucleotide DNA array
    • Nagata,T., Takahashi,Y., Ishii,Y. et al. (2003) Profiling of genes differentially expressed between fetal liver and postnatal liver using high-density oligonucleotide DNA array. Int. J. Mol. Med., 11, 713-721.
    • (2003) Int. J. Mol. Med. , vol.11 , pp. 713-721
    • Nagata, T.1    Takahashi, Y.2    Ishii, Y.3
  • 82
    • 0028149573 scopus 로고
    • Functional cytochrome P4503A isoforms in human embryonic tissues: Expression during organogenesis
    • Yang,H.Y., Lee,Q.P., Rettie,A.E. and Juchau,M.R. (1994) Functional cytochrome P4503A isoforms in human embryonic tissues: Expression during organogenesis. Mol. Pharmacol., 46, 922-928.
    • (1994) Mol. Pharmacol. , vol.46 , pp. 922-928
    • Yang, H.Y.1    Lee, Q.P.2    Rettie, A.E.3    Juchau, M.R.4
  • 84
    • 0035233159 scopus 로고    scopus 로고
    • Effect of two years' supplementation with natural antioxidants on vitamin and trace element status biomarkers: Preliminary data of the SU.VI.MAX study
    • Malvy,D.J., Favier,A., Faure,H., Preziosi,P., Galan,P., Arnaud,J., Roussel,A.M., Briancon,S. and Hercberg,S. (2001) Effect of two years' supplementation with natural antioxidants on vitamin and trace element status biomarkers: Preliminary data of the SU.VI.MAX study. Cancer Detect. Prev, 25, 479-485.
    • (2001) Cancer Detect. Prev , vol.25 , pp. 479-485
    • Malvy, D.J.1    Favier, A.2    Faure, H.3    Preziosi, P.4    Galan, P.5    Arnaud, J.6    Roussel, A.M.7    Briancon, S.8    Hercberg, S.9
  • 85
    • 0345369343 scopus 로고    scopus 로고
    • Smoking, plasma vitamins C, E, retinol, and carotene, and fatal prostate cancer: Seventeen-year follow-up of the prospective basel study
    • Eichholzer,M., Stahelin,H.B., Ludin,E. and Bernasconi,F. (1999) Smoking, plasma vitamins C, E, retinol, and carotene, and fatal prostate cancer: seventeen-year follow-up of the prospective basel study. Prostate, 38, 189-198.
    • (1999) Prostate , vol.38 , pp. 189-198
    • Eichholzer, M.1    Stahelin, H.B.2    Ludin, E.3    Bernasconi, F.4
  • 89
    • 10344238570 scopus 로고    scopus 로고
    • Alpha-Tocopherol and beta-carotene supplements and lung cancer incidence in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention study: Effects of base-line characteristics and study compliance
    • Albanes,D., Heinonen,O.P., Taylor,P.R. et al. (1996) Alpha-Tocopherol and beta-carotene supplements and lung cancer incidence in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention study: Effects of base-line characteristics and study compliance. J. Natl Cancer Inst., 88, 1560-1570.
    • (1996) J. Natl Cancer Inst. , vol.88 , pp. 1560-1570
    • Albanes, D.1    Heinonen, O.P.2    Taylor, P.R.3
  • 90
    • 0035830288 scopus 로고    scopus 로고
    • Maternal folate supplementation in pregnancy and protection against acute lymphoblastic leukaemia in childhood: A case-control study
    • Thompson,J.R., Gerald,P.F., Willoughby,M.L. and Armstrong,B.K. (2001) Maternal folate supplementation in pregnancy and protection against acute lymphoblastic leukaemia in childhood: A case-control study. Lancet, 358, 1935-1940.
    • (2001) Lancet , vol.358 , pp. 1935-1940
    • Thompson, J.R.1    Gerald, P.F.2    Willoughby, M.L.3    Armstrong, B.K.4
  • 91
    • 0031471132 scopus 로고    scopus 로고
    • Backtracking leukemia to birth: Identification of clonotypic gene fusion sequences in neonatal blood spots
    • Gale,K.B., Ford,A.M., Repp,R., Borkhardt,A., Keller,C., Eden,O.B. and Greaves,M.F. (1997) Backtracking leukemia to birth: Identification of clonotypic gene fusion sequences in neonatal blood spots. Proc. Natl Acad. Sci. USA, 94, 13950-13954.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 13950-13954
    • Gale, K.B.1    Ford, A.M.2    Repp, R.3    Borkhardt, A.4    Keller, C.5    Eden, O.B.6    Greaves, M.F.7
  • 94
    • 14944341750 scopus 로고    scopus 로고
    • In utero origins of cancer: Maternal dietary vitamin E, fetal oxidative DNA damage and postnatal carcinogenesis in p53 knockout mice
    • Chen,C.S. and Wells,P.G. (2004) In utero origins of cancer: Maternal dietary vitamin E, fetal oxidative DNA damage and postnatal carcinogenesis in p53 knockout mice. Ann. NY Acad. Sci., 1031, 395-398.
    • (2004) Ann. NY Acad. Sci. , vol.1031 , pp. 395-398
    • Chen, C.S.1    Wells, P.G.2


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