Prenatal chromosomal diversification of leukemia in monozygotic twins

Genes Chromosomes and Cancer

Volumn 37, Issue 4, 2003, Pages 406-411

  Kempski, Helena ^a,b   Mensa Bonsu, Karen A ^a   Kearney, Lyndal ^c   Jalali, G Reza ^d   Hann, Ian ^b   Khurshid, Mohammed ^e   Greaves, Mel ^c  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^c INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^d SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

^e AGA KHAN UNIVERSITY HOSPITAL   (Pakistan)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE LYMPHOBLASTIC LEUKEMIA; ACUTE MONOCYTIC LEUKEMIA; ARTICLE; CASE REPORT; CHILD; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DELETION; GENE FUSION; GENE MAPPING; HUMAN; KARYOTYPE; LEUKEMIA; MALE; MONOZYGOTIC TWINS; PRIORITY JOURNAL;

CHROMOSOME ABERRATIONS; CHROMOSOME DELETION; CLONE CELLS; DISEASES IN TWINS; DNA-BINDING PROTEINS; HUMANS; INFANT; LEUKEMIA, MONOCYTIC, ACUTE; MALE; PROTO-ONCOGENE PROTEINS C-ETS; REPRESSOR PROTEINS; TWINS, MONOZYGOTIC;

EID: 0038461929     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/gcc.10233     Document Type: Article

References (35)

1. Alexander FE, Patheal SL, Biondi A, Brandalise S, Cabrera M-E, Chan LC, Chen Z, Cimino G, Cordoba J-C, Gu L-J, Hussein H, Ishii E, Kamel AM, Labra S, Magalhães IQ, Mizutani S, Petridou E, Pombo de Oliveira M, Yuen P, Wiemels JL, Greaves MF. 2001. Transplacental chemical exposure and risk of infant leukemia with MLL gene fusion. Cancer Res 61:2542-2546.
2. Bardelli A, Cahill DP, Lederer G, Speicher MR, Kinzler KW, Vogelstein B, Lengauer C. 2001. Carcinogen-specific induction of genetic instability. Proc Natl Acad Sci USA 98:5770-5775.
3. Breivik J, Gaudernack G. 1999. Genomic instability, DNA methylation, and natural selection in colorectal carcinogenesis. Cancer Biol 9:245-254.
4. Cahill DP, Lengauer C, Yu J, Riggins GJ, Willson JKV, Markowitz SD, Kinzler KW, Vogelstein B. 1998. Mutations of mitotic checkpoint genes in human cancers. Nature 392:300-303.
5. Chaganti RSK, Miller DR, Meyers PA, German J. 1979. Cytogenetic evidence of the intrauterine origin of acute leukemia in monozygotic twins. N Engl J Med 300:1032-1034.
6. Chessells JM, Harrison CJ, Kempski H, Webb DKH, Wheatley K, Hann IM, Stevens RF, Harrison G, Gibson BE. 2002. Clinical features, cytogenetics and outcome in acute lymphoblastic and myeloid leukaemia in infancy: report from the MRC Childhood Leukaemia working party. Leukemia 16:776-784.
7. Clarkson B, Boyse EA. 1971. Possible explanation of the high concordance for acute leukaemia in monozygous twins. Lancet 1:699-701.
8. Felix CA. 1998. Secondary leukemias induced by topoisomerase-targeted drugs. Biochim Biophys Acta 1400:233-255.
9. Ford AM, Ridge SA, Cabrera ME, Mahmoud H, Steel CM, Chan LC, Greaves MF. 1993. In utero origin of rearrangements in the trithorax-related oncogene in infant leukaemias. Nature 363:358-360.
10. Ford AM, Pombo-de-Oliveira MS, McCarthy KP, MacLean JM, Carrico KC, Vincent RF, Greaves M. 1997. Monoclonal origin of concordant T-cell malignancy in identical twins. Blood 89:281-285.
11. Ford AM, Bennett CA, Price CM, Bruin MCA, Van Wering ER, Greaves M. 1998. Fetal origins of the TEL-AML1 fusion gene in identical twins with leukemia. Proc Natl Acad Sci USA 95:4584-4588.
12. Gale KB, Ford AM, Repp R, Borkhardt A, Keller C, Eden OB, Greaves MF. 1997. Backtracking leukemia to birth: identification of clonotypic gene fusion sequences in neonatal blood spots. Proc Natl Acad Sci USA 94:13950-13954.
13. Ghadimi BM, Sackett DL, Difilippantonio MJ, Schröck E, Neumann T, Jauho A, Auer G, Ried T. 2000. Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations. Genes Chromosomes Cancer 27:183-190.
14. Gill Super HJ, Rothberg PG, Kobayashi H, Freeman AI, Diaz MO, Rowley JD. 1994. Clonal, non-constitutional rearrangements of the MLL gene in infant twins with acute lymphoblastic leukemia: in utero chromosome rearrangement of 11q23. Blood 83:641-644.
15. Gisselsson D, Jonson T, Petersen A, Strömbeck B, Dal Cin P, Höglund M, Mitelman F, Mertens F, Mandahl N. 2001. Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors. Proc Natl Acad Sci USA 98:12683-12688.
16. Greaves MF. 1997. Aetiology of acute leukaemia. Lancet 349:344-349.
17. Hartley SE, Sainsbury C. 1981. Acute leukaemia and the same chromosome abnormality in monozygotic twins. Hum Genet 58:408-410.
18. Hilton HB, Lewis IC, Trowell HR. 1970. C group trisomy in identical twins with acute leukemia. Blood 35:222-226.
19. Keith L, Brown ER, Fields C, Stepto R. 1973. Unifying concepts of leukemia. In: Dutcher RM, Chieco-Bianchi L. Bibl haemat (No. 39). Basel: S. Karger.
20. MacMahon B, Levy MA. 1964. Prenatal origin of childhood leukaemia. Evidence from twins. N Engl J Med 22:1082-1085.
21. Maia AT, Ford AM, Jalali GR, Harrison CJ, Taylor GM, Eden OB, Greaves MF. 2001. Molecular tracking of leukemogenesis in a triplet pregnancy. Blood 98:478-482.
22. Megonigal MD, Rappaport EF, Jones DH, Williams TM, Lovett BD, Kelly KM, Lerou PH, Moulton T, Budarf ML, Felix CA. 1998. t(11;22)(q23;q11.2) in acute myeloid leukemia of infant twins fuses MLL with hCDCrel, a cell division cycle gene in the genomic region of deletion in DiGeorge and velocardiofacial syndromes. Proc Natl Acad Sci USA 95:6413-6418.
23. Mitelman F, Johansson B, Mertens F, editors. 2002. Mitelman database of chromosome aberrations in cancer. May be accessed at http://cgap.nci.nih.gov/Chromosomes/Mitelman
24. Mrozek K, Heinonen K, Bloomfield CD. 2001. Clinical importance of cytogenetics in acute myeloid leukaemia. Baillieres Best Pract Res Clin Haematol 14:19-47.
25. Pedersen-Bjergaard J. 2002. Chemicals and leukemia. In: Henderson ES, Lister TA, Greaves MF, editors. Leukemia, Seventh Ed. Philadelphia. Saunders: p 171-194.
26. Richkind KE, Loew T, Meisner L, Harris C, Wason D. 1998. Identical cytogenetic clones and clonal evolution in pediatric monozygotic twins with acute myeloid leukaemia: presymptomatic disease detection by interphase fluorescence in situ hybridisation and review of the literature. J Pediatr Hematol Oncol 20:264-267.
27. Ross JA, Potter JD, Reaman GH, Pendergrass TW, Robison LL. 1996. Maternal exposure to potential inhibitors of DNA topoisomerase II and infant leukemia (United States): a report from the Children's Cancer Group. Cancer Causes Control 7:581-590.
28. Simmons HM, Oseth L, Nguyen P, O'Leary M, Conklin KF, Hirsch B. 2002. Cytogenetic and molecular heterogeneity of 7q36/12p13 rearrangements in childhood AML. Leukemia 16:2408-2416.
29. Strick R, Strissel PL, Borgers S, Smith SL, Rowley JD. 2000. Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia. Proc Natl Acad Sci USA 97:4790-4795.
30. Tosi S, Harbott J, Teigler-Schlegel A, Haas OA, Pirc-Danoewinata H, Harrison CJ, Biondi A, Cazzaniga G, Kempski H, Scherer SW, Kearney L. 2000. t(7;12)(q36;p13), a new recurrent translocation involving ETV6 in infant leukaemia. Genes Chromosomes Cancer 29:325-332.
31. von Lindern M, Fornerod M, Soekarman N, van Baal S, Jaegle M, Hagemeijer A, Bootsma D, Grosveld G. 1992. Translocation t(6;9) in acute non-lymphocytic leukaemia results in the formation of a DEK-CAN fusion gene. Baillieres Clin Haematol 5:857-879.
32. Wiemels JL, Cazzaniga G, Daniotti M, Eden OB, Addison GM, Masera G, Saha V, Biondi A, Greaves MF. 1999a. Prenatal origin of acute lymphoblastic leukaemia in children. Lancet 354:1499-1503.
33. Wiemels JL, Ford AM, Van Wering ER, Postma A, Greaves M. 1999b. Protracted and variable latency of acute lymphoblastic leukemia after TEL-AML1 gene fusion in utero. Blood 94:1057-1062.
34. Wiemels JL, Pagnamenta A, Taylor GM, Eden OB, Alexander FE, Greaves MF, UK Childhood Cancer Study Investigators. 1999c. A lack of a functional NAD(P)H:quinone oxidoreductase allele is selectively associated with pediatric leukemias that have MLL fusions. Cancer Res 59:4095-4099.
35. Zuelzer WW, Cox DE. 1969. Genetic aspects of leukemia. Semin Hematol 228:228.