Phosphate activation in the ground state of purine nucleoside phosphorylase

Journal of the American Chemical Society

Volumn 128, Issue 24, 2006, Pages 7765-7771

  Deng, Hua ^a   Murkin, Andrew S ^a   Schramm, Vern L ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; ELECTRONIC STRUCTURE; FOURIER TRANSFORM INFRARED SPECTROSCOPY; GROUND STATE; HYDROLYSIS; NEGATIVE IONS;

PHOSPHATE MOIETY; PURINE NUCLEOSIDE PHOSPHORYLASE (PNP); RIBOSE 1-PHOSPHATE (R1P);

PHOSPHATES;

DNA BASE; PHOSPHATE; PURINE NUCLEOSIDE PHOSPHORYLASE; RIBOSE; RIBOSE 1 PHOSPHATE; WATER;

ARTICLE; BINDING AFFINITY; BOND STRENGTH; COMPLEX FORMATION; COVALENT BOND; ELECTROCHEMISTRY; ELECTRONIC STRUCTURE; ELECTRONICS; ENZYME BINDING; GROUND STATE; HYDROGEN BOND; HYDROLYSIS; INFRARED SPECTROSCOPY; LYSIS; MICHAELIS COMPLEX; MOLECULAR INTERACTION; NUCLEOSIDE SYNTHESIS; PHOSPHOROLYSIS; PROTON TRANSPORT; SOLVOLYSIS; SYNTHESIS; TRANSITION STATE;

BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; HUMANS; HYDROGEN BONDING; HYDROLYSIS; MODELS, CHEMICAL; PHOSPHATES; PURINE-NUCLEOSIDE PHOSPHORYLASE; RIBOSE; RIBOSEMONOPHOSPHATES; SOLVENTS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 33745383208     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0570281     Document Type: Article

References (34)

1. Tremblay, L. W.; Zhang, G.; Dai, J.; Dunaway-Mariano, D.; Allen, K. N. J. Am. Chem. Soc. 2005, 127, 5298-9.
2. Lahiri, S. D.; Zhang, G.; Dunaway-Mariano, D.; Allen, K. N. Science 2003, 299, 2067-71.
3. Allin, C.; Gerwert, K. Biochemistry 2001, 40, 3037-46.
4. Du, X.; Frei, H.; Kim, S. H. J. Biol. Chem. 2000, 275, 8492-500.
5. Liu, M.; Krasteva, M.; Barth, A. Biophys. J. 2005, 89, 4352-63.
6. Abbreviations: PNP, human purine nucleoside phosphorylase; R1P, α-D-ribose 1-phosphate; ImmH, Immucillin-H.
7. Fedorov, A.; Shi, W.; Kicska, G.; Fedorov, E.; Tyler, P. C.; Furneaux, R. H.; Hanson, J. C.; Gainsford, G. J.; Larese, J. Z.; Schramm, V. L.; Almo, S. C. Biochemistry 2001, 40, 853-60.
8. Lewandowicz, A.; Shi, W.; Evans, G. B.; Tyler, P. C.; Furneaux, R. H.; Basso, L. A.; Santos, D. S.; Almo, S. C.; Schramm, V. L. Biochemistry 2003, 42, 6057-66.
9. Deng, H.; Lewandowicz, A.; Schramm, V. L.; Callender, R. J. Am. Chem. Soc. 2004, 126, 9516-7.
10. Stoeckler, J. D. Developments in Cancer Chemotherapy. In Developments in Cancer Chemotherapy; Glazer, R. J., Ed.; CRC Press Inc.: Boca Raton, FL, 1984; pp 35-60.
11. Bzowska, A.; Kulikowska, E.; Shugar, D. Pharma. Ther. 2000, 88, 349-425.
12. Mazzella, L. J.; Parkin, D. W.; Tyler, P. C.; Furneaux, R. H.; Schramm, V. L. J. Am. Chem. Soc. 1996, 118, 2111-2.
13. Schramm, V. L.; Grubmeyer, C. Prog. Nucleic Acid Res. Mol. Biol. 2004, 78, 261-304.
14. Kline, P. C.; Schramm, V. L. Biochemistry 1992, 31, 5964-73.
15. Canduri, F.; dos Santos, D. M.; Silva, R. G.; Mendes, M. A.; Basso, L. A.; Palma, M. S.; de Azevedo, W. F.; Santos, D. S. Biochem. Biophys. Res. Commun. 2004, 313, 907-14.
16. Lewandowicz, A.; Schramm, V. L. Biochemistry 2004, 43, 1458-68.
17. Mertz, E. L.; Leikin, S. Biochemistry 2004, 43, 14901-12.
18. Martinez-Liarte, J. H.; Iriarte, A.; Martinez-Carrion, M. Biochemistry 1992, 31, 2712-19.
19. Wang, J. H.; Xiao, D. G.; Deng, H.; Webb, M. R.; Callender, R. Biochemistry 1998, 37, 11106-16.
20. Cheng, H.; Sukal, S.; Deng, H.; Leyh, T. S.; Callender, R. Biochemistry 2001, 40, 4035-43.
21. Chakrabarti, P. P.; Suveyzdis, Y.; Wittinghofer, A.; Gerwert, K. J. Biol. Chem. 2004, 279, 46226-33.
22. Deng, H.; Wang, J.; Ray, W. J.; Callender, R. J. Phys. Chem. B 1998, 102, 3617-23.
23. Deng, H.; Lewandowicz, A.; Cahill, S. M.; Furneaux, R. H.; Tyler, P. C.; Girvin, M. E.; Callender, R. H.; Schramm, V. L. Biochemistry 2004, 43, 1980-7.
24. Deng, H.; Cahill, S. M.; Abad, J. L.; Lewandowicz, A.; Callender, R. H.; Schramm, V. L.; Jones, R. A. Biochemistry 2004, 43, 15966-74.
25. Jordan, F.; Patrick, J. A.; Salamone, S., Jr. J. Biol. Chem. 1979, 254, 2384-6.
26. Cohn, M.; Hu, A. Proc. Natl. Acad. Sci. U.S.A. 1978, 75, 200-3.
27. Shi, W.; Basso, L. A.; Santos, D. S.; Tyler, P. C.; Furneaux, R. H.; Blanchard, J. S.; Almo, S. C.; Schramm, V. L. Biochemistry 2001, 40, 8204-15.
28. Sauve, A. A.; Cahill, S. M.; Zech, S. G.; Basso, L. A.; Lewandowicz, A.; Santos, D. S.; Grubmeyer, C.; Evans, G. B.; Furneaux, R. H.; Tyler, P. C.; McDermott, A.; Girvin, M. E.; Schramm, V. L. Biochemistry 2003, 42, 5694-705.
29. Cheng, H.; Nikolic-Hughes, I.; Wang, J. H.; Deng, H.; O'Brien, P. J.; Wu, L.; Zhang, Z. Y.; Herschlag, D.; Callender, R. J. Am. Chem. Soc. 2002, 124, 11295-306.
30. This conclusion assumes that the higher symmetric stretch frequency and the highest asymmetric stretch are associated with this phosphate. If other frequencies are associated with this phosphate, the average frequency will be even lower, corresponding to even stronger hydrogen bonding.
31. Erion, M. D.; Takabayashi, K.; Smith, H. B.; Kessi, J.; Wagner, S.; Honger, S.; Shames, S. L.; Ealick, S. E. Biochemistry 1997, 36, 11725-34.
32. Mao, C.; Cook, W. J.; Zhou, M.; Koszalka, G. W.; Krenitsky, T. A.; Ealick, S. E. Structure 1997, 5, 1373-83.
33. de Azevedo, W. F., Jr.; Canduri, F.; dos Santos, D. M.; Silva, R. G.; de Oliveira, J. S.; de Carvalho, L. P.; Basso, L. A.; Mendes, M. A.; Palma, M. S.; Santos, D. S. Biochim. Biophys. Res. Commun. 2003, 308, 545-52.
34. Mao, C.; Cook, W. J.; Zhou, M.; Federov, A. A.; Almo, S. C.; Ealick, S. E. Biochemistry 1998, 37, 7135-46.