Purine nucleoside phosphorylase. 1. Structure - Function studies

Biochemistry

Volumn 36, Issue 39, 1997, Pages 11725-11734

  Erion, Mark D ^a,d   Takabayashi, Kenji ^a   Smith, Harry B ^a   Kessi, Janine ^a   Wagner, Sylvia ^a   Hönger, Sybille ^a   Shames, Spencer L ^b,e   Ealick, Steven E ^c  

^a CIBA GEIGY LTD   (Switzerland)

^b NOVARTIS PHARMA AG   (Switzerland)

^c Department of Obstetrics Gynecology   (United States)

^d Gensia Inc   (United States)

^e GENZYME CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PURINE NUCLEOSIDE PHOSPHORYLASE;

ARTICLE; CONFORMATIONAL TRANSITION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; HUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

BINDING SITES; CATALYSIS; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROGEN BONDING; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; NUCLEOSIDES; PROTEIN CONFORMATION; PURINE-NUCLEOSIDE PHOSPHORYLASE; PURINES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

FELIS CATUS;

EID: 0030817010     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi961969w     Document Type: Article

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