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Volumn 1096, Issue 1, 2006, Pages 180-195

Ascending neuropathology in the CNS of a mutant SOD1 mouse model of amyotrophic lateral sclerosis

Author keywords

Apoptosis; Degeneration; Dendritic cell; Disease progression; Inflammation; Lymphocyte

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE;

EID: 33745242487     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2006.04.029     Document Type: Article
Times cited : (24)

References (97)
  • 1
    • 0035833937 scopus 로고    scopus 로고
    • Immune reactivity in a mouse model of familial ALS correlates with disease progression
    • Alexianu M.E., Kozovska M., and Appel S.H. Immune reactivity in a mouse model of familial ALS correlates with disease progression. Neurology 57 (2001) 1282-1289
    • (2001) Neurology , vol.57 , pp. 1282-1289
    • Alexianu, M.E.1    Kozovska, M.2    Appel, S.H.3
  • 4
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J., and Steinman R.M. Dendritic cells and the control of immunity. Nature 392 (1998) 245-252
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 5
    • 84907127109 scopus 로고
    • Pinacyanol erthrosinate as a stain for mast cells
    • Bensley S.H. Pinacyanol erthrosinate as a stain for mast cells. Stain Technol. 27 (1952) 269-273
    • (1952) Stain Technol. , vol.27 , pp. 269-273
    • Bensley, S.H.1
  • 7
    • 26244436018 scopus 로고    scopus 로고
    • The beta2 integrin CD11c distinguishes a subset of cytotoxic pulmonary T cells with potent antiviral effects in vitro and in vivo
    • Beyer M., Wang H., Peters N., Doths S., Koerner-Rettberg C., Openshaw P.J., and Schwarze J. The beta2 integrin CD11c distinguishes a subset of cytotoxic pulmonary T cells with potent antiviral effects in vitro and in vivo. Respir. Res. 6 (2005) 70
    • (2005) Respir. Res. , vol.6 , pp. 70
    • Beyer, M.1    Wang, H.2    Peters, N.3    Doths, S.4    Koerner-Rettberg, C.5    Openshaw, P.J.6    Schwarze, J.7
  • 8
    • 3943102116 scopus 로고    scopus 로고
    • Unraveling the mechanisms involved in motor neuron degeneration in ALS
    • Bruijn L.I., Miller T.M., and Cleveland D.W. Unraveling the mechanisms involved in motor neuron degeneration in ALS. Annu. Rev. Neurosci. 27 (2004) 723-749
    • (2004) Annu. Rev. Neurosci. , vol.27 , pp. 723-749
    • Bruijn, L.I.1    Miller, T.M.2    Cleveland, D.W.3
  • 9
    • 0033957706 scopus 로고    scopus 로고
    • Immunocytochemical study on the distribution of nitrotyrosine in the brain of the transgenic mice expressing a human Cu/Zn SOD mutation
    • Cha C.I., Chung Y.H., Shin C.M., Shin D.H., Kim Y.S., Gurney M.E., and Lee K.W. Immunocytochemical study on the distribution of nitrotyrosine in the brain of the transgenic mice expressing a human Cu/Zn SOD mutation. Brain Res. 853 (2000) 156-161
    • (2000) Brain Res. , vol.853 , pp. 156-161
    • Cha, C.I.1    Chung, Y.H.2    Shin, C.M.3    Shin, D.H.4    Kim, Y.S.5    Gurney, M.E.6    Lee, K.W.7
  • 11
    • 0027296350 scopus 로고
    • Amyotrophic lateral sclerosis: lower motor neuron disease spreading to upper motor neurons
    • Chou S.M., and Norris F.H. Amyotrophic lateral sclerosis: lower motor neuron disease spreading to upper motor neurons. Muscle Nerve 16 (1993) 864-869
    • (1993) Muscle Nerve , vol.16 , pp. 864-869
    • Chou, S.M.1    Norris, F.H.2
  • 12
    • 0038031654 scopus 로고    scopus 로고
    • Immunohistochemical study on the distribution of alpha-synuclein in the central nervous system of transgenic mice expressing a human Cu/Zn superoxide dismutase mutation
    • Chung Y.H., Joo K.M., Kim M.J., and Cha C.I. Immunohistochemical study on the distribution of alpha-synuclein in the central nervous system of transgenic mice expressing a human Cu/Zn superoxide dismutase mutation. Neurosci. Lett. 342 (2003) 151-154
    • (2003) Neurosci. Lett. , vol.342 , pp. 151-154
    • Chung, Y.H.1    Joo, K.M.2    Kim, M.J.3    Cha, C.I.4
  • 13
    • 0038015538 scopus 로고    scopus 로고
    • Immunohistochemical study on the aggregation of ubiquitin in the central nervous system of the transgenic mice expressing a human Cu/Zn SOD mutation
    • Chung Y.H., Joo K.M., Lee Y.J., Kim M.J., and Cha C.I. Immunohistochemical study on the aggregation of ubiquitin in the central nervous system of the transgenic mice expressing a human Cu/Zn SOD mutation. Neurol. Res. 25 (2003) 395-400
    • (2003) Neurol. Res. , vol.25 , pp. 395-400
    • Chung, Y.H.1    Joo, K.M.2    Lee, Y.J.3    Kim, M.J.4    Cha, C.I.5
  • 14
    • 1542268893 scopus 로고    scopus 로고
    • Reactive astrocytes express PARP in the central nervous system of SOD(G93A) transgenic mice
    • Chung Y.H., Joo K.M., Lee Y.J., Shin D.H., and Cha C.I. Reactive astrocytes express PARP in the central nervous system of SOD(G93A) transgenic mice. Brain Res. 1003 (2004) 199-204
    • (2004) Brain Res. , vol.1003 , pp. 199-204
    • Chung, Y.H.1    Joo, K.M.2    Lee, Y.J.3    Shin, D.H.4    Cha, C.I.5
  • 15
    • 0035666597 scopus 로고    scopus 로고
    • Mechanisms of neurodegeneration in amyotrophic lateral sclerosis
    • Cluskey S., and Ramsden D.B. Mechanisms of neurodegeneration in amyotrophic lateral sclerosis. Mol. Pathol. 54 (2001) 386-392
    • (2001) Mol. Pathol. , vol.54 , pp. 386-392
    • Cluskey, S.1    Ramsden, D.B.2
  • 17
    • 0027946294 scopus 로고
    • Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis
    • Dal Canto M.C., and Gurney M.E. Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis. Am. J. Pathol. 145 (1994) 1271-1279
    • (1994) Am. J. Pathol. , vol.145 , pp. 1271-1279
    • Dal Canto, M.C.1    Gurney, M.E.2
  • 18
    • 0023829847 scopus 로고
    • Hypoglossal, trigeminal, and facial motoneuron involvement in amyotrophic lateral sclerosis
    • DePaul R., Abbs J.H., Caligiuri M., Gracco V.L., and Brooks B.R. Hypoglossal, trigeminal, and facial motoneuron involvement in amyotrophic lateral sclerosis. Neurology 38 (1988) 281-283
    • (1988) Neurology , vol.38 , pp. 281-283
    • DePaul, R.1    Abbs, J.H.2    Caligiuri, M.3    Gracco, V.L.4    Brooks, B.R.5
  • 19
    • 0032785475 scopus 로고    scopus 로고
    • Extrapyramidal involvement in amyotrophic lateral sclerosis: backward falls and retropulsion
    • Desai J., and Swash M. Extrapyramidal involvement in amyotrophic lateral sclerosis: backward falls and retropulsion. J. Neurol. Neurosurg. Psychiatry 67 (1999) 214-216
    • (1999) J. Neurol. Neurosurg. Psychiatry , vol.67 , pp. 214-216
    • Desai, J.1    Swash, M.2
  • 21
    • 0035079788 scopus 로고    scopus 로고
    • The motor cortex and amyotrophic lateral sclerosis
    • Eisen A., and Weber M. The motor cortex and amyotrophic lateral sclerosis. Muscle Nerve 24 (2001) 564-573
    • (2001) Muscle Nerve , vol.24 , pp. 564-573
    • Eisen, A.1    Weber, M.2
  • 22
    • 0035500386 scopus 로고    scopus 로고
    • Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis
    • Elliott J.L. Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis. Brain Res. Mol. Brain Res. 95 (2001) 172-178
    • (2001) Brain Res. Mol. Brain Res. , vol.95 , pp. 172-178
    • Elliott, J.L.1
  • 23
    • 0027473452 scopus 로고
    • Lymphocytic infiltrates in the spinal cord in amyotrophic lateral sclerosis
    • Engelhardt J.I., Tajti J., and Appel S.H. Lymphocytic infiltrates in the spinal cord in amyotrophic lateral sclerosis. Arch. Neurol. 50 (1993) 30-36
    • (1993) Arch. Neurol. , vol.50 , pp. 30-36
    • Engelhardt, J.I.1    Tajti, J.2    Appel, S.H.3
  • 24
    • 0035865406 scopus 로고    scopus 로고
    • Brain dendritic cells and macrophages/microglia in central nervous system inflammation
    • Fischer H.G., and Reichmann G. Brain dendritic cells and macrophages/microglia in central nervous system inflammation. J. Immunol. 166 (2001) 2717-2726
    • (2001) J. Immunol. , vol.166 , pp. 2717-2726
    • Fischer, H.G.1    Reichmann, G.2
  • 25
    • 0034193965 scopus 로고    scopus 로고
    • Phenotype and functions of brain dendritic cells emerging during chronic infection of mice with Toxoplasma gondii
    • Fischer H.G., Bonifas U., and Reichmann G. Phenotype and functions of brain dendritic cells emerging during chronic infection of mice with Toxoplasma gondii. J. Immunol. 164 (2000) 4826-4834
    • (2000) J. Immunol. , vol.164 , pp. 4826-4834
    • Fischer, H.G.1    Bonifas, U.2    Reichmann, G.3
  • 26
    • 84907125573 scopus 로고
    • A reliable and sensitive method to localize terminal degeneration and lysosomes in the central nervous system
    • Gallyas F., Wolff J.R., Böttcher H., and Zaborszky L. A reliable and sensitive method to localize terminal degeneration and lysosomes in the central nervous system. Stain Technol. 55 (1980) 299-306
    • (1980) Stain Technol. , vol.55 , pp. 299-306
    • Gallyas, F.1    Wolff, J.R.2    Böttcher, H.3    Zaborszky, L.4
  • 27
    • 0346094107 scopus 로고    scopus 로고
    • Suppressive silver methods-a tool for identifying axotomy-induced neuron degeneration
    • Grant G., Hollander H., and Aldskogius H. Suppressive silver methods-a tool for identifying axotomy-induced neuron degeneration. Brain Res. Bull. 62 (2004) 261-269
    • (2004) Brain Res. Bull. , vol.62 , pp. 261-269
    • Grant, G.1    Hollander, H.2    Aldskogius, H.3
  • 30
    • 0037240427 scopus 로고    scopus 로고
    • Programmed cell death in amyotrophic lateral sclerosis
    • Guegan C., and Przedborski S. Programmed cell death in amyotrophic lateral sclerosis. J. Clin. Invest. 111 (2003) 153-161
    • (2003) J. Clin. Invest. , vol.111 , pp. 153-161
    • Guegan, C.1    Przedborski, S.2
  • 31
    • 0035437866 scopus 로고    scopus 로고
    • Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis
    • Guegan C., Vila M., Rosoklija G., Hays A.P., and Przedborski S. Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis. J. Neurosci. 21 (2001) 6569-6576
    • (2001) J. Neurosci. , vol.21 , pp. 6569-6576
    • Guegan, C.1    Vila, M.2    Rosoklija, G.3    Hays, A.P.4    Przedborski, S.5
  • 32
    • 1542373666 scopus 로고    scopus 로고
    • Microglia, macrophages, perivascular macrophages, and pericytes: a review of function and identification
    • Guillemin G.J., and Brew B.J. Microglia, macrophages, perivascular macrophages, and pericytes: a review of function and identification. J. Leukoc. Biol. 75 (2004) 388-397
    • (2004) J. Leukoc. Biol. , vol.75 , pp. 388-397
    • Guillemin, G.J.1    Brew, B.J.2
  • 34
    • 0037137502 scopus 로고    scopus 로고
    • Differential vulnerability of cranial motoneurons in mouse models with motor neuron degeneration
    • Haenggeli C., and Kato A.C. Differential vulnerability of cranial motoneurons in mouse models with motor neuron degeneration. Neurosci. Lett. 335 (2002) 39-43
    • (2002) Neurosci. Lett. , vol.335 , pp. 39-43
    • Haenggeli, C.1    Kato, A.C.2
  • 35
    • 0032125587 scopus 로고    scopus 로고
    • Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS
    • Hall E.D., Oostveen J.A., and Gurney M.E. Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS. Glia 23 (1998) 249-256
    • (1998) Glia , vol.23 , pp. 249-256
    • Hall, E.D.1    Oostveen, J.A.2    Gurney, M.E.3
  • 36
    • 0033625507 scopus 로고    scopus 로고
    • Motor neuronal death in sporadic amyotrophic lateral sclerosis (ALS) is not apoptotic. A comparative study of ALS and chronic aluminium chloride neurotoxicity in New Zealand white rabbits
    • He B.P., and Strong M.J. Motor neuronal death in sporadic amyotrophic lateral sclerosis (ALS) is not apoptotic. A comparative study of ALS and chronic aluminium chloride neurotoxicity in New Zealand white rabbits. Neuropathol. Appl. Neurobiol. 26 (2000) 150-160
    • (2000) Neuropathol. Appl. Neurobiol. , vol.26 , pp. 150-160
    • He, B.P.1    Strong, M.J.2
  • 38
    • 33644821966 scopus 로고    scopus 로고
    • The chemokine MCP-1 and the dendritic and myeloid cells it attracts are increased in the mSOD1 mouse model of ALS
    • Henkel J.S., Beers D.R., Siklos L., and Appel S.H. The chemokine MCP-1 and the dendritic and myeloid cells it attracts are increased in the mSOD1 mouse model of ALS. Mol. Cell. Neurosci. 31 (2006) 427-437
    • (2006) Mol. Cell. Neurosci. , vol.31 , pp. 427-437
    • Henkel, J.S.1    Beers, D.R.2    Siklos, L.3    Appel, S.H.4
  • 39
    • 0036062628 scopus 로고    scopus 로고
    • Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis
    • Hensley K., Floyd R.A., Gordon B., Mou S., Pye Q.N., Stewart C., West M., and Williamson K. Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis. J. Neurochem. 82 (2002) 365-374
    • (2002) J. Neurochem. , vol.82 , pp. 365-374
    • Hensley, K.1    Floyd, R.A.2    Gordon, B.3    Mou, S.4    Pye, Q.N.5    Stewart, C.6    West, M.7    Williamson, K.8
  • 41
    • 19444374567 scopus 로고    scopus 로고
    • Activation of the stress-activated MAP kinase, p38, but not JNK in cortical motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in transgenic mice
    • Holasek S.S., Wengenack T.M., Kandimalla K.K., Montano C., Gregor D.M., Curran G.L., and Poduslo J.F. Activation of the stress-activated MAP kinase, p38, but not JNK in cortical motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in transgenic mice. Brain Res. 1045 (2005) 185-198
    • (2005) Brain Res. , vol.1045 , pp. 185-198
    • Holasek, S.S.1    Wengenack, T.M.2    Kandimalla, K.K.3    Montano, C.4    Gregor, D.M.5    Curran, G.L.6    Poduslo, J.F.7
  • 42
    • 0028998222 scopus 로고
    • Antigen-driven induction of CD11c on intestinal intraepithelial lymphocytes and CD8+ T cells in vivo
    • Huleatt J.W., and Lefrancois L. Antigen-driven induction of CD11c on intestinal intraepithelial lymphocytes and CD8+ T cells in vivo. J. Immunol. 154 (1995) 5684-5693
    • (1995) J. Immunol. , vol.154 , pp. 5684-5693
    • Huleatt, J.W.1    Lefrancois, L.2
  • 44
    • 0026605961 scopus 로고
    • Immunologic reactions in amyotrophic lateral sclerosis brain and spinal cord tissue
    • Kawamata T., Akiyama H., Yamada T., and McGeer P.L. Immunologic reactions in amyotrophic lateral sclerosis brain and spinal cord tissue. Am. J. Pathol. 140 (1992) 691-707
    • (1992) Am. J. Pathol. , vol.140 , pp. 691-707
    • Kawamata, T.1    Akiyama, H.2    Yamada, T.3    McGeer, P.L.4
  • 45
    • 0025727137 scopus 로고
    • Changes in sizes of cortical and lower motor neurons in amyotrophic lateral sclerosis
    • Kiernan J.A., and Hudson A.J. Changes in sizes of cortical and lower motor neurons in amyotrophic lateral sclerosis. Brain 114 pt. 2 (1991) 843-853
    • (1991) Brain , vol.114 , Issue.PART 2 , pp. 843-853
    • Kiernan, J.A.1    Hudson, A.J.2
  • 46
    • 0030887622 scopus 로고    scopus 로고
    • Midbrain dopaminergic neuronal degeneration in a transgenic mouse model of familial amyotrophic lateral sclerosis
    • Kostic V., Gurney M.E., Deng H.-X., Siddique T., Epstein C.J., and Przedborski S. Midbrain dopaminergic neuronal degeneration in a transgenic mouse model of familial amyotrophic lateral sclerosis. Ann. Neurol. 41 (1997) 497-504
    • (1997) Ann. Neurol. , vol.41 , pp. 497-504
    • Kostic, V.1    Gurney, M.E.2    Deng, H.-X.3    Siddique, T.4    Epstein, C.J.5    Przedborski, S.6
  • 47
    • 0036219703 scopus 로고    scopus 로고
    • Dendritic cells are present in ischemic brain after permanent middle cerebral artery occlusion in the rat
    • Kostulas N., Li H.L., Xiao B.G., Huang Y.M., Kostulas V., and Link H. Dendritic cells are present in ischemic brain after permanent middle cerebral artery occlusion in the rat. Stroke 33 (2002) 1129-1134
    • (2002) Stroke , vol.33 , pp. 1129-1134
    • Kostulas, N.1    Li, H.L.2    Xiao, B.G.3    Huang, Y.M.4    Kostulas, V.5    Link, H.6
  • 49
    • 0025220976 scopus 로고
    • Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain
    • Lawson L.J., Perry V.H., Dri P., and Gordon S. Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain. Neuroscience 39 (1990) 151-170
    • (1990) Neuroscience , vol.39 , pp. 151-170
    • Lawson, L.J.1    Perry, V.H.2    Dri, P.3    Gordon, S.4
  • 51
    • 1642450672 scopus 로고    scopus 로고
    • Up-regulation and altered distribution of lysyl oxidase in the central nervous system of mutant SOD1 transgenic mouse model of amyotrophic lateral sclerosis
    • Li P.A., He Q., Cao T., Yong G., Szauter K.M., Fong K.S., Karlsson J., Keep M.F., and Csiszar K. Up-regulation and altered distribution of lysyl oxidase in the central nervous system of mutant SOD1 transgenic mouse model of amyotrophic lateral sclerosis. Brain Res. Mol. Brain Res. 120 (2004) 115-122
    • (2004) Brain Res. Mol. Brain Res. , vol.120 , pp. 115-122
    • Li, P.A.1    He, Q.2    Cao, T.3    Yong, G.4    Szauter, K.M.5    Fong, K.S.6    Karlsson, J.7    Keep, M.F.8    Csiszar, K.9
  • 52
    • 0242319531 scopus 로고    scopus 로고
    • Myeloid marker expression on antiviral CD8+ T cells following an acute virus infection
    • Lin Y., Roberts T.J., Sriram V., Cho S., and Brutkiewicz R.R. Myeloid marker expression on antiviral CD8+ T cells following an acute virus infection. Eur. J. Immunol. 33 (2003) 2736-2743
    • (2003) Eur. J. Immunol. , vol.33 , pp. 2736-2743
    • Lin, Y.1    Roberts, T.J.2    Sriram, V.3    Cho, S.4    Brutkiewicz, R.R.5
  • 53
    • 0033765916 scopus 로고    scopus 로고
    • Extramotor involvement in ALS: PET studies with the GABA(A) ligand [(11)C]flumazenil
    • Lloyd C.M., Richardson M.P., Brooks D.J., Al Chalabi A., and Leigh P.N. Extramotor involvement in ALS: PET studies with the GABA(A) ligand [(11)C]flumazenil. Brain 123 pt. 11 (2000) 2289-2296
    • (2000) Brain , vol.123 , Issue.PART 11 , pp. 2289-2296
    • Lloyd, C.M.1    Richardson, M.P.2    Brooks, D.J.3    Al Chalabi, A.4    Leigh, P.N.5
  • 54
    • 0042632880 scopus 로고    scopus 로고
    • Genetic epidemiology of amyotrophic lateral sclerosis
    • Majoor-Krakauer D., Willems P.J., and Hofman A. Genetic epidemiology of amyotrophic lateral sclerosis. Clin. Genet. 63 (2003) 83-101
    • (2003) Clin. Genet. , vol.63 , pp. 83-101
    • Majoor-Krakauer, D.1    Willems, P.J.2    Hofman, A.3
  • 55
    • 0029011894 scopus 로고
    • A direct comparison of GFAP immunocytochemistry and GFAP concentration in various regions of ethanol-fixed rat and mouse brain
    • Martin P.M., and O'Callaghan J.P. A direct comparison of GFAP immunocytochemistry and GFAP concentration in various regions of ethanol-fixed rat and mouse brain. J. Neurosci. Methods 58 (1995) 181-192
    • (1995) J. Neurosci. Methods , vol.58 , pp. 181-192
    • Martin, P.M.1    O'Callaghan, J.P.2
  • 57
    • 0036787810 scopus 로고    scopus 로고
    • Inflammatory processes in amyotrophic lateral sclerosis
    • McGeer P.L., and McGeer E.G. Inflammatory processes in amyotrophic lateral sclerosis. Muscle Nerve 26 (2002) 459-470
    • (2002) Muscle Nerve , vol.26 , pp. 459-470
    • McGeer, P.L.1    McGeer, E.G.2
  • 58
    • 0033594227 scopus 로고    scopus 로고
    • Distribution and phenotype of dendritic cells and resident tissue macrophages in the dura mater, leptomeninges, and choroid plexus of the rat brain as demonstrated in wholemount preparations
    • McMenamin P.G. Distribution and phenotype of dendritic cells and resident tissue macrophages in the dura mater, leptomeninges, and choroid plexus of the rat brain as demonstrated in wholemount preparations. J. Comp. Neurol. 405 (1999) 553-562
    • (1999) J. Comp. Neurol. , vol.405 , pp. 553-562
    • McMenamin, P.G.1
  • 59
    • 0025309427 scopus 로고
    • The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodies
    • Metlay J.P., Witmer-Pack M.D., Agger R., Crowley M.T., Lawless D., and Steinman R.M. The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodies. J. Exp. Med. 171 (1990) 1753-1771
    • (1990) J. Exp. Med. , vol.171 , pp. 1753-1771
    • Metlay, J.P.1    Witmer-Pack, M.D.2    Agger, R.3    Crowley, M.T.4    Lawless, D.5    Steinman, R.M.6
  • 61
    • 0022443737 scopus 로고
    • Familial adult motor neuron disease: amyotrophic lateral sclerosis
    • Mulder D.W., Kurland L.T., Offord K.P., and Beard C.M. Familial adult motor neuron disease: amyotrophic lateral sclerosis. Neurology 36 (1986) 511-517
    • (1986) Neurology , vol.36 , pp. 511-517
    • Mulder, D.W.1    Kurland, L.T.2    Offord, K.P.3    Beard, C.M.4
  • 62
    • 0033506382 scopus 로고    scopus 로고
    • Stains for differential diagnosis of degenerative dementias
    • Munoz D.G. Stains for differential diagnosis of degenerative dementias. Biotech. Histochem. 74 (1999) 311-320
    • (1999) Biotech. Histochem. , vol.74 , pp. 311-320
    • Munoz, D.G.1
  • 63
    • 0026505155 scopus 로고
    • Immunocytochemical and ultrastructural studies of upper motor neurons in amyotrophic lateral sclerosis
    • Murayama S., Bouldin T.W., and Suzuki K. Immunocytochemical and ultrastructural studies of upper motor neurons in amyotrophic lateral sclerosis. Acta Neuropathol. (Berl) 83 (1992) 518-524
    • (1992) Acta Neuropathol. (Berl) , vol.83 , pp. 518-524
    • Murayama, S.1    Bouldin, T.W.2    Suzuki, K.3
  • 64
    • 0029942834 scopus 로고    scopus 로고
    • Midbrain dopaminergic neurons in the mouse: computer-assisted mapping
    • Nelson E.L., Liang C.-L., Sinton C.M., and German D.C. Midbrain dopaminergic neurons in the mouse: computer-assisted mapping. J. Comp. Neurol. 369 (1996) 361-371
    • (1996) J. Comp. Neurol. , vol.369 , pp. 361-371
    • Nelson, E.L.1    Liang, C.-L.2    Sinton, C.M.3    German, D.C.4
  • 65
    • 0025313039 scopus 로고
    • Axonal swellings in the corticospinal tracts in amyotrophic lateral sclerosis
    • Okamoto K., Hirai S., Shoji M., Senoh Y., and Yamazaki T. Axonal swellings in the corticospinal tracts in amyotrophic lateral sclerosis. Acta Neuropathol. (Berl) 80 (1990) 222-226
    • (1990) Acta Neuropathol. (Berl) , vol.80 , pp. 222-226
    • Okamoto, K.1    Hirai, S.2    Shoji, M.3    Senoh, Y.4    Yamazaki, T.5
  • 67
    • 0030773791 scopus 로고    scopus 로고
    • Distinct pathological features of the gallyas- and tau-positive glia in the Parkinsonism-dementia complex and amyotrophic lateral sclerosis of Guam
    • Oyanagi K., Makifuchi T., Ohtoh T., Chen K.M., Gajdusek D.C., and Chase T.N. Distinct pathological features of the gallyas- and tau-positive glia in the Parkinsonism-dementia complex and amyotrophic lateral sclerosis of Guam. J. Neuropathol. Exp. Neurol. 56 (1997) 308-316
    • (1997) J. Neuropathol. Exp. Neurol. , vol.56 , pp. 308-316
    • Oyanagi, K.1    Makifuchi, T.2    Ohtoh, T.3    Chen, K.M.4    Gajdusek, D.C.5    Chase, T.N.6
  • 69
    • 0034040531 scopus 로고    scopus 로고
    • Differential progression of Dark Neuron and Fluoro-Jade labelling in the rat hippocampus following pilocarpine-induced status epilepticus
    • Poirier J.L., Capek R., and De Koninck Y. Differential progression of Dark Neuron and Fluoro-Jade labelling in the rat hippocampus following pilocarpine-induced status epilepticus. Neuroscience 97 (2000) 59-68
    • (2000) Neuroscience , vol.97 , pp. 59-68
    • Poirier, J.L.1    Capek, R.2    De Koninck, Y.3
  • 70
    • 0942287085 scopus 로고    scopus 로고
    • Programmed cell death in amyotrophic lateral sclerosis: a mechanism of pathogenic and therapeutic importance
    • Przedborski S. Programmed cell death in amyotrophic lateral sclerosis: a mechanism of pathogenic and therapeutic importance. Neurologist 10 (2004) 1-7
    • (2004) Neurologist , vol.10 , pp. 1-7
    • Przedborski, S.1
  • 71
    • 0036347321 scopus 로고    scopus 로고
    • Dendritic cells and dendritic-like microglia in focal cortical ischemia of the mouse brain
    • Reichmann G., Schroeter M., Jander S., and Fischer H.G. Dendritic cells and dendritic-like microglia in focal cortical ischemia of the mouse brain. J. Neuroimmunol. 129 (2002) 125-132
    • (2002) J. Neuroimmunol. , vol.129 , pp. 125-132
    • Reichmann, G.1    Schroeter, M.2    Jander, S.3    Fischer, H.G.4
  • 72
    • 0027164824 scopus 로고
    • Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
    • Rosen D.R. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 364 (1993) 362
    • (1993) Nature , vol.364 , pp. 362
    • Rosen, D.R.1
  • 73
    • 0033768506 scopus 로고    scopus 로고
    • Quantification of upper motor neuron loss in amyotrophic lateral sclerosis
    • Rosler K.M., Truffert A., Hess C.W., and Magistris M.R. Quantification of upper motor neuron loss in amyotrophic lateral sclerosis. Clin. Neurophysiol. 111 (2000) 2208-2218
    • (2000) Clin. Neurophysiol. , vol.111 , pp. 2208-2218
    • Rosler, K.M.1    Truffert, A.2    Hess, C.W.3    Magistris, M.R.4
  • 74
    • 0033950543 scopus 로고    scopus 로고
    • Fluoro-Jade: novel fluorochromes for detecting toxicant-induced neuronal degeneration
    • Schmued L.C., and Hopkins K.J. Fluoro-Jade: novel fluorochromes for detecting toxicant-induced neuronal degeneration. Toxicol. Pathol. 28 (2000) 91-99
    • (2000) Toxicol. Pathol. , vol.28 , pp. 91-99
    • Schmued, L.C.1    Hopkins, K.J.2
  • 75
    • 0030901162 scopus 로고    scopus 로고
    • Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration
    • Schmued L.C., Albertson C., and Slikker W. Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration. Brain Res. 751 (1997) 37-46
    • (1997) Brain Res. , vol.751 , pp. 37-46
    • Schmued, L.C.1    Albertson, C.2    Slikker, W.3
  • 76
    • 0033636254 scopus 로고    scopus 로고
    • Intracerebral recruitment and maturation of dendritic cells in the onset and progression of experimental autoimmune encephalomyelitis
    • Serafini B., Columba-Cabezas S., Di Rosa F., and Aloisi F. Intracerebral recruitment and maturation of dendritic cells in the onset and progression of experimental autoimmune encephalomyelitis. Am. J. Pathol. 157 (2000) 1991-2002
    • (2000) Am. J. Pathol. , vol.157 , pp. 1991-2002
    • Serafini, B.1    Columba-Cabezas, S.2    Di Rosa, F.3    Aloisi, F.4
  • 77
    • 0035070937 scopus 로고    scopus 로고
    • Transgenic mouse model for familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation
    • Shibata N. Transgenic mouse model for familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation. Neuropathology 21 (2001) 82-92
    • (2001) Neuropathology , vol.21 , pp. 82-92
    • Shibata, N.1
  • 78
    • 0025244904 scopus 로고
    • Ultrastructure of PkC(II/III)-immunopositive structures in rat primary visual cortex
    • Stichel C.C., Singer W., and Zilles K. Ultrastructure of PkC(II/III)-immunopositive structures in rat primary visual cortex. Exp. Brain Res. 82 (1990) 575-584
    • (1990) Exp. Brain Res. , vol.82 , pp. 575-584
    • Stichel, C.C.1    Singer, W.2    Zilles, K.3
  • 79
    • 0033951734 scopus 로고    scopus 로고
    • Application of silver degeneration stains for neurotoxicity testing
    • Switzer III R.C. Application of silver degeneration stains for neurotoxicity testing. Toxicol. Pathol. 28 (2000) 70-83
    • (2000) Toxicol. Pathol. , vol.28 , pp. 70-83
    • Switzer III, R.C.1
  • 80
    • 0030858052 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis with numerous axonal spheroids in the corticospinal tract and massive degeneration of the cortex
    • Takahashi T., Yagishita S., Amano N., Yamaoka K., and Kamei T. Amyotrophic lateral sclerosis with numerous axonal spheroids in the corticospinal tract and massive degeneration of the cortex. Acta Neuropathol. (Berl) 94 (1997) 294-299
    • (1997) Acta Neuropathol. (Berl) , vol.94 , pp. 294-299
    • Takahashi, T.1    Yagishita, S.2    Amano, N.3    Yamaoka, K.4    Kamei, T.5
  • 81
    • 15444363122 scopus 로고    scopus 로고
    • Neuritic beading induced by activated microglia is an early feature of neuronal dysfunction toward neuronal death by inhibition of mitochondrial respiration and axonal transport
    • Takeuchi H., Mizuno T., Zhang G., Wang J., Kawanokuchi J., Kuno R., and Suzumura A. Neuritic beading induced by activated microglia is an early feature of neuronal dysfunction toward neuronal death by inhibition of mitochondrial respiration and axonal transport. J. Biol. Chem. 280 (2005) 10444-10454
    • (2005) J. Biol. Chem. , vol.280 , pp. 10444-10454
    • Takeuchi, H.1    Mizuno, T.2    Zhang, G.3    Wang, J.4    Kawanokuchi, J.5    Kuno, R.6    Suzumura, A.7
  • 82
    • 0024847142 scopus 로고
    • Phosphotyrosine antibodies specifically label ameboid microglia in vitro and ramified microglia in vivo
    • Tillotson M.L., and Wood J.G. Phosphotyrosine antibodies specifically label ameboid microglia in vitro and ramified microglia in vivo. Glia 2 (1989) 412-419
    • (1989) Glia , vol.2 , pp. 412-419
    • Tillotson, M.L.1    Wood, J.G.2
  • 84
    • 0025185079 scopus 로고
    • Immunohistochemical characterization of the inflammatory infiltrate in amyotrophic lateral sclerosis
    • Troost D., Van den Oord J.J., and Vianney de Jong J.M. Immunohistochemical characterization of the inflammatory infiltrate in amyotrophic lateral sclerosis. Neuropathol. Appl. Neurobiol. 16 (1990) 401-410
    • (1990) Neuropathol. Appl. Neurobiol. , vol.16 , pp. 401-410
    • Troost, D.1    Van den Oord, J.J.2    Vianney de Jong, J.M.3
  • 85
    • 0036968626 scopus 로고    scopus 로고
    • Sporadic amyotrophic lateral sclerosis with circumscribed temporal atrophy: a report of an autopsy case without dementia and with ubiquitinated intraneuronal inclusions
    • Tsuchiya K., Takahashi M., Shiotsu H., Akiyama H., Haga C., Watabiki S., Taki K., Nakano I., and Ikeda K. Sporadic amyotrophic lateral sclerosis with circumscribed temporal atrophy: a report of an autopsy case without dementia and with ubiquitinated intraneuronal inclusions. Neuropathology 22 (2002) 308-316
    • (2002) Neuropathology , vol.22 , pp. 308-316
    • Tsuchiya, K.1    Takahashi, M.2    Shiotsu, H.3    Akiyama, H.4    Haga, C.5    Watabiki, S.6    Taki, K.7    Nakano, I.8    Ikeda, K.9
  • 86
    • 0029966363 scopus 로고    scopus 로고
    • Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions
    • Tu P.H., Raju P., Robinson K.A., Gurney M.E., Trojanowski J.Q., and Lee V.M. Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 3155-3160
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 3155-3160
    • Tu, P.H.1    Raju, P.2    Robinson, K.A.3    Gurney, M.E.4    Trojanowski, J.Q.5    Lee, V.M.6
  • 87
    • 1842471942 scopus 로고    scopus 로고
    • Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study
    • Turner M.R., Cagnin A., Turkheimer F.E., Miller C.C., Shaw C.E., Brooks D.J., Leigh P.N., and Banati R.B. Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study. Neurobiol. Dis. 15 (2004) 601-609
    • (2004) Neurobiol. Dis. , vol.15 , pp. 601-609
    • Turner, M.R.1    Cagnin, A.2    Turkheimer, F.E.3    Miller, C.C.4    Shaw, C.E.5    Brooks, D.J.6    Leigh, P.N.7    Banati, R.B.8
  • 88
    • 0028123075 scopus 로고
    • Phenotypic differences between human monocytes/macrophages and microglial cells studied in situ and in vitro
    • Ulvestad E., Williams K., Mork S., Antel J., and Nyland H. Phenotypic differences between human monocytes/macrophages and microglial cells studied in situ and in vitro. J. Neuropathol. Exp. Neurol. 53 (1994) 492-501
    • (1994) J. Neuropathol. Exp. Neurol. , vol.53 , pp. 492-501
    • Ulvestad, E.1    Williams, K.2    Mork, S.3    Antel, J.4    Nyland, H.5
  • 89
    • 17844395669 scopus 로고    scopus 로고
    • Neuroinflammation in the pathogenesis of amyotrophic lateral sclerosis
    • Weydt P., and Moller T. Neuroinflammation in the pathogenesis of amyotrophic lateral sclerosis. NeuroReport 16 (2005) 527-531
    • (2005) NeuroReport , vol.16 , pp. 527-531
    • Weydt, P.1    Moller, T.2
  • 90
    • 0026344258 scopus 로고
    • Degeneration of the substantia nigra in familial amyotrophic lateral sclerosis
    • Wolf H.K., Crain B.J., and Siddique T. Degeneration of the substantia nigra in familial amyotrophic lateral sclerosis. Clin. Neuropathol. 10 (1991) 291-296
    • (1991) Clin. Neuropathol. , vol.10 , pp. 291-296
    • Wolf, H.K.1    Crain, B.J.2    Siddique, T.3
  • 91
    • 0036685522 scopus 로고    scopus 로고
    • Inflammation in neurodegenerative disease-A double-edged sword
    • Wyss-Coray T., and Mucke L. Inflammation in neurodegenerative disease-A double-edged sword. Neuron 35 (2002) 419-432
    • (2002) Neuron , vol.35 , pp. 419-432
    • Wyss-Coray, T.1    Mucke, L.2
  • 92
    • 0034780179 scopus 로고    scopus 로고
    • Fluoro-Jade and silver methods: application to the neuropathology of scrapie, a transmissible spongiform encephalopathy
    • Ye X., Carp R.I., Schmued L.C., and Scallet A.C. Fluoro-Jade and silver methods: application to the neuropathology of scrapie, a transmissible spongiform encephalopathy. Brain Res. Brain Res. Protoc. 8 (2001) 104-112
    • (2001) Brain Res. Brain Res. Protoc. , vol.8 , pp. 104-112
    • Ye, X.1    Carp, R.I.2    Schmued, L.C.3    Scallet, A.C.4
  • 93
    • 8744291752 scopus 로고    scopus 로고
    • Combined MR spectroscopic imaging and diffusion tensor MRI visualizes corticospinal tract degeneration in amyotrophic lateral sclerosis
    • Yin H., Lim C.C., Ma L., Gao Y., Cai Y., Li D., Liang Y., and Guo X. Combined MR spectroscopic imaging and diffusion tensor MRI visualizes corticospinal tract degeneration in amyotrophic lateral sclerosis. J. Neurol. 251 (2004) 1249-1254
    • (2004) J. Neurol. , vol.251 , pp. 1249-1254
    • Yin, H.1    Lim, C.C.2    Ma, L.3    Gao, Y.4    Cai, Y.5    Li, D.6    Liang, Y.7    Guo, X.8
  • 94
    • 1642294641 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis with dementia: the clinicopathological spectrum
    • Yoshida M. Amyotrophic lateral sclerosis with dementia: the clinicopathological spectrum. Neuropathology 24 (2004) 87-102
    • (2004) Neuropathology , vol.24 , pp. 87-102
    • Yoshida, M.1
  • 95
    • 0037206646 scopus 로고    scopus 로고
    • Degeneration of corticospinal and bulbospinal systems in the superoxide dismutase 1 (G93A G1H) transgenic mouse model of familial amyotrophic lateral sclerosis
    • Zang D.W., and Cheema S.S. Degeneration of corticospinal and bulbospinal systems in the superoxide dismutase 1 (G93A G1H) transgenic mouse model of familial amyotrophic lateral sclerosis. Neurosci. Lett. 332 (2002) 99-102
    • (2002) Neurosci. Lett. , vol.332 , pp. 99-102
    • Zang, D.W.1    Cheema, S.S.2
  • 96
    • 8144224974 scopus 로고    scopus 로고
    • Magnetic resonance imaging reveals neuronal degeneration in the brainstem of the superoxide dismutase 1 transgenic mouse model of amyotrophic lateral sclerosis
    • Zang d.W., Yang Q., Wang H.X., Egan G., Lopes E.C., and Cheema S.S. Magnetic resonance imaging reveals neuronal degeneration in the brainstem of the superoxide dismutase 1 transgenic mouse model of amyotrophic lateral sclerosis. Eur. J. Neurosci. 20 (2004) 1745-1751
    • (2004) Eur. J. Neurosci. , vol.20 , pp. 1745-1751
    • Zang, d.W.1    Yang, Q.2    Wang, H.X.3    Egan, G.4    Lopes, E.C.5    Cheema, S.S.6
  • 97
    • 12344279991 scopus 로고    scopus 로고
    • Basophilia, acidophilia and argyrophilia of "dark" (compacted) neurons during their formation, recovery or death in an otherwise undamaged environment
    • Zsombok A., Toth Z., and Gallyas F. Basophilia, acidophilia and argyrophilia of "dark" (compacted) neurons during their formation, recovery or death in an otherwise undamaged environment. J. Neurosci. Methods 142 (2005) 145-152
    • (2005) J. Neurosci. Methods , vol.142 , pp. 145-152
    • Zsombok, A.1    Toth, Z.2    Gallyas, F.3


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