Distribution and phenotype of dendritic cells and resident tissue macrophages in the dura mater, leptomeninges, and choroid plexus of the rat brain as demonstrated in wholemount preparations

Journal of Comparative Neurology

Volumn 405, Issue 4, 1999, Pages 553-562

  McMenamin, Paul G ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Antigen presenting cells; Auto immune disease; Central nervous system; Immune privilege; Inflammation; Meninges

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; AUTOIMMUNITY; BRAIN TISSUE; CHOROID PLEXUS; DENDRITIC CELL; DURA MATER; FEMALE; HOST RESISTANCE; IMMUNOPATHOGENESIS; INFLAMMATORY INFILTRATE; MACROPHAGE FUNCTION; MENINX; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0033594227     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9861(19990322)405:4<553::AID-CNE8>3.0.CO;2-6     Document Type: Article

References (49)

1. Braun JS, Kaisling B, Le Hir M, Zenker W. 1993. Cellular components of the immune barrier in the spinal meninges and dorsal root ganglion of the normal rat: immunohistochemical (MHC class II) and electron-microscopic observations. Cell Tissue Research. 273:209-217.
2. Brenan M, Puklavec M. 1992. The MRC OX-62 antigen: A useful marker in the purification of rat veiled cells with the biochemical properties of an integrin. J exp Med. 175:1457-1465.
3. Butler TL, McMenamin PG. 1996. Immunohistochemical study of choroid and iris whole-mounts in the early and late stages of experimental auto-immune uveoretinitis. Invest Ophthalmol Vis Sci 37:2195-2210.
4. + T lymphocytes in the central nervous system. Clin Exp Immunol ;98:313-318.
5. Cella M, Sallusto F, Lanzaveccheia A. 1997. Origin, maturation and antigen presenting function of dendritic cells. Current Opinion Immunology. 9:10-16.
6. Claassen E, Alder LT, Adler FL. 1996. Double immunocytochemical staining for in situ study of allotype distribution during an anti-TNP immune response in chimeric rabbits. J Histochem Cytochem 34:989-994.
7. Cserr HF, Knopf PM. 1992 Cervical lymphatics, the blood-brain barrier and the immunoreactivity of the brain - a new view. Immunol Today 13:507-512.
8. Damoiseaux JGMC, Dopp EA, Neefjes JJ, Beelen RHJ, Dijkstra CD. 1989. Heterogeneity of macrophages in the rat evidenced by variability in determinants: Two new anti-rat macrophage antibodies against a heterodimer of 160 and 95 kd (CD11/CD18). J Leukocyte Biol 46:556-564.
9. Damoiseaux JGMC, Dopp EA, Calame D, Chao D, MacPherson GG, Dijkstra CD. 1994. Rat macrophage lysosomal membrane antigen recognized by monoclonal antibody ED1. Immunology 83:140-147.
10. Dijkstra CD, Dopp EA, Joling P, Kraal G. 1985. The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognised by monoclonal antibodies ED1, ED2 and ED3. Immunology 54:589-599.
11. Dimlich RV, Keller JT, Strauss TA, Fritts MJ. 1991. Linear arrays of homogeneous mast cells in the dura mater of the rat. J Neurocytology 20, 485-503.
12. Ford AL, Goodsall AL, Hickey WF, Sedgwick JD. 1995. Normal adult ramified microglia separated from other central nervous sytem macrophages by flow cytometric sorting. J Immunol 154:4309-4321.
13. Forrester JV, Lumsden L, Liversidge J, Kuppner M, Mesri M. 1995. Immunoregulation of uveoretinal inflammation. Prog Ret Eye Res 14:393-412.
14. Frick B, von During M, Andres KH. 1997. Topography and immunocytochemical characterisation of nerve fibers in the leptomeninges compartments of the rat. A light and electron microscopic study. Cell Tissue Res 287:11-22.
15. Gehrmann J, Banati RB, Kreutzberg GW. 1993. Microglia in the immune surveillance of the brain: human microglia constitutively express HLA-DR molecules. J Neuroimmunol 48:189-198.
16. Hickey WF, Kimura H. 1998. Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo. Science 239:290-292
17. Hickey WF, Vass K, Lassmann H. 1992. Bone marrow-derived elements in the central nervous system: an immunohistochemical and ultastructural survey of rat chimeras. J Neuropathol Exp Neurol 51:246-256.
18. Jordan FL, Thomas WE. 1988. Brain macrophages: questions of origin and interrelationships. Brain Res Rev 13:165-178.
19. Kitz K, Lassmann H, Wisniewski HM. 1981. Isolated leptomeninges of the spinal cord: an ideal tool to study inflammatory reaction in EAE. Acta Neuropathol Berl Suppl VII:179-181.
20. Knopf PM, Cserr HF, Nolan SC, Wu TY, Harling-Berg CJ. 1995. Physiology and immunology of lymphatic drainage of interstial and cerebrospinal fluid from the brain. Neuropath Appl Neurobiol 21:175-180.
21. Lackner AA, Smith MO, Munn RJ, Martfeld DJ, Gardner MB, Marx PA, Dandekar S. 1991. Localization of simian immunodeficiency virus in the central nervous system of Rhesus monkeys. Amer J Path 139:609-621
22. Liu LM, MacPherson GG. 1991. Lymph-borne (veiled) dendritic cells can acquire and present intestinally administered antigens. Immunol 73: 281-286.
23. McMenamin PG. 1994. Immunocompetent cells in the anterior segment. Prog Ret Eye Res 13:555-589.
24. McMenamin PG, Crewe J. 1995. Endotoxin-induced uveitis: kinetics and phenotype of the inflammatory cell infiltrate and the response of the resident tissue macrophages and dendritic cells in the iris and ciliary body. Invest Ophthalmol Vis Sci 36:1949-1959
25. McMenamin PG, Crewe JM, Morrison S, Holt PG. 1994. Immunomorphologic studies of macrophages and MHC class II-positive dendritic cells in the iris and ciliary body of the rat, mouse and human eye. Invest. Ophthalmol Vis Sci 35:3234-3250.
26. McMenamin PG, Forrester JV. 1999. Dendritic cells in the central nervous system and eye and their associated supporting tissues. In Lotze MT, Thomson AW, editors. Dendritic cells: biology and clinical applications. London: Academic Press. p 205-248.
27. Macatonia SE, Knight SC, Edwards AJ, Griffiths S, Fryer P. 1987. Localization of antigen on lymph node dendritic cells after exposure to the contact senssitizer fluorscein isothiocyanate. J Exp Med 166:1654-1667.
28. Mason DW, Arthur RP, Dallman MJ, Green JR, Spickett GP, Thomas ML. 1983. Functions of rat T-lymphocyte subsets isolated by means of monoclonal antibodies. Immunol Rev 74:57-82.
29. Matyszak MK Lawson JL, Perry VH, Gordon S. 1992. Stromal macrophages of the choroid plexus situated at an interface between the brain and peripheral immune system constitutively express MHC class II antigens. J Neuroimmunol 40:173-182.
30. Matyszak MK, Perry VH. 1996a. The potential role of dendritic cells in immune-mediated inflammatory diseases in the central nervous sys-tem. Neuroscience 74:599-608.
31. Matyszak MK, Perry VH. 1996b. A comparison of leucocyte responses to heat-killed bacillus Calmette-Geurin in different CNS compartments. Neuropath Appl Neurobiol 22:44-53.
32. Penfold PL, Provis JM, Liew SCK. 1993. Human retinal microglia express phenotypic characteristics in common with dendritic antigen-presenting cells. J Neuroimmunol 45:183-192.
33. Perry VH, Andersson P-B, Gordon S. 1993. Macrophages and inflammation in the central nervous system. TINS 16:268-273.
34. Rinner WA, Bauer J, Schmidts M, Lassmann H, Hickey WF. 1995. Resident microglia and hematogenous macrophages as phagocytes in adoptively transferred experimental autoimmune encephalomyelitis: an investigation using rat radiation bone marrow chimeras, Glia 14,257-66.
35. Robinson AP, White TM, Mason DW. 1986. Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the later recognizing complement receptor type 3. Immunology 57:239-247.
36. Romani N, Schuler G. 1989. Structural and functional relationships between epidermal langerhans cells and dendritic cells. Res Immunol 140:895-898.
37. Schon-Hegrad MA, Oliver J, McMenamin PG, Holt PG. 1991. Studies on the density, distribution and surface phenotype of intraepithelial class II MHC (Ia)-bearing dendritic cells (DC) in the conducting airways. J exp Med 173:1345-1356.
38. Sedgwick JD. 1995. Immune surveillance and autoantigen recognition in the central nervous system. Aust NZ J Med 25:784-792.
39. Sedgwick JD. 1997. T-Lymphocyte activation and regulation in the central nervous system. Biochem Soc Trans 75:673-679.
40. Sedgwick JD, Hickey WF. 1997 Antigen presentation in the central nervous system. In: Keane RW, Hickey WF, editors. Immunology of the nervous system. New York: Oxford University Press. p 364-418.
41. Sedgwick JD, Mossner R, Imrich H, Dories R, Butcher GW, ter Meulen V. 1991. Isolation and direct characterisation of resident microglia from the normal and inflammed central nervous system. Proc Nat Acad Sci USA 88:7438-42.
42. Serot JM, Foliguet B, Bene MC, Faure GC. 1997. Ultrastructural and immmunohistochemical evidence for dendritic-like cells within the human choroid plexus epithelium. Neuroreport 8:1995-1998.
43. Sminia T, Dijkstra CD. 1986. The origin of osteoclasts: an immunohistochemical study on macrophages and osteoclasts in embryonic rat bone. Calc Tiss Res 39:263-6.
44. Sminia T, de Groot CJA, Dijkstra CD, Koetsier JC, Polman CH. 1987. Macrophages in the central nervous system of the rat. Immunobiol 174:43-50.
45. Steinman RM. 1991. The dendritic cell system and its role in immunogenicity. Annu Rev Immunol 9:271-296.
46. Steptoe RJ, Holt PG, McMenamin PG. 1997. Major histocompatability complex class II-positive dendritic cells in the iris of the rat eye: In situ development from major histocompatability complex class II-negative precursors. Invest Ophthalmol Vis Sci 38:2639-2648.
47. van Dam A-M, Bauer J, Tilders FJH, Berkenbosch F. 1995. Endotoxin-induced appearance of immunoreactive interleukin-1β in ramified microglia in rat brain: alight and electron microscopic study. Neuroscience 65:815-826.
48. Van den Berg TK, Breve JJ, Damoiseaux JG, Dopp EA, Kelm S, Crocker PR, Dijkstra CD, Kraal, G. 1992. Sialoadhesin on macrophages: its identification as a lymphocyte adhesion molecule. J Exp Med 176: 647-55.
49. Witmer-Pack MD, Olivier W, Valinsky J, Schuler G, Steinman RM. 1987. Granulocyte/macrophage colony-stimulating factor is essential for the viability and function of cultured murine epidermal Langerhans cells. J exp Med 166:1484-1498.