Activation of Akt by mechanical stretching in human epidermal keratinocytes

Experimental Dermatology

Volumn 15, Issue 5, 2006, Pages 356-361

  Yano, Shoichiro ^a,b   Komine, Mayumi ^a   Fujimoto, Manabu ^a   Okochi, Hitoshi ^b   Tamaki, Kunihiko ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

Author keywords

Akt; Apoptosis; Keratinocytes; Mechanical stretching

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; CALCIUM CHANNEL BLOCKING AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; GADOLINIUM; KERATIN; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SILICONE; WORTMANNIN; APOPTOSIS REGULATORY PROTEIN; CALCIUM; EPIDERMAL GROWTH FACTOR; GLYCOGEN SYNTHASE KINASE 3;

APOPTOSIS; ARTICLE; ATTENUATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; EPIDERMIS CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; KERATINOCYTE; MECHANICAL STIMULATION; NORMAL HUMAN; SIGNAL TRANSDUCTION; CELL CULTURE; MECHANICAL STRESS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS REGULATORY PROTEINS; CALCIUM; CELLS, CULTURED; EPIDERMAL GROWTH FACTOR; GLYCOGEN SYNTHASE KINASE 3; HUMANS; KERATINOCYTES; MAP KINASE SIGNALING SYSTEM; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, EPIDERMAL GROWTH FACTOR; STRESS, MECHANICAL;

EID: 33745232776     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/j.0906-6705.2006.00425.x     Document Type: Article

References (38)

1. Timson B F. Evaluation of animal models for the study of exercise-induced muscle enlargement. J Appl Physiol 1991: 71: 372-374.
2. Goldspink G, Scutt A, Martindale J, Jaenicke T, Turay L, Gerlach G F. Stretch and force generation induce rapid hypertrophy and myosin isoform gene switching in adult skeletal muscle. Biochem Soc Trans 1991: 19: 368-373.
3. Booth F W, Tseng B S, Fluck M, Carson J A. Molecular and cellular adaptation of muscle in response to physical training. Acta Physiol Scand 1998: 162: 343-350.
4. Salter D M, Wallace WH, Robb J E, Caldwell H, Wright M O. Human bone cell hyperpolarization response to cyclical mechanical strain is mediated by an interleukin-1beta autocrine/paracrine loop. J Bone Miner Res 2000: 15: 1746-1755.
5. Kurata K, Uemura T, Nemoto A, et al. Mechanical strain effect on bone-resorbing activity and messenger RNA expressions of marker enzymes in isolated osteoclast culture. J Bone Miner Res 2001: 16: 722-730.
6. Yano S, Komine M, Fujimoto M, Okochi H, Tamaki K. Mechanical stretching in vitro regulates signal transduction pathways and cellular proliferation in human epidermal keratinocytes. J Invest Dermatol 2004: 122: 783-790.
7. Yang W B, Hao F, Song Z Q, Yang X C, Ni B. Apoptosis of the dermal papilla cells of hair follicle associated with the expression of gene HSPCO16 in vitro. Exp Dermatol 2005: 14: 209-214.
8. Ackah E, Yu J, Zoellner S, et al. Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis. J Clin Invest 2005: 115: 2119-2127.
9. Scholle F, Bendt K M, Raab-Traub N. Epstein-Barr virus LMP2A transforms epithelial cells, inhibits cell differentiation, and activates Akt. J Virol 2000: 74: 10681-10689.
10. Di-Poi N, Tan N S, Michalik L, Wahli W, Desvergne B. Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway. Mol Cell 2002: 10: 721-733.
11. Boukamp P, Petrussevska R T, Breitkreutz D, Hornung J, Markham A, Fusenig N E. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J Cell Biol 1988: 106: 761-771.
12. Livingstone C, Patel G, Jones N. ATF-2 contains a phosphorylation-dependent transcriptional activation domain. EMBO J 1995: 14: 1785-1797.
13. Dimmeler S, Assmus B, Hermann C, Haendeler J, Zeiher A M. Fluid shear stress stimulates phospholylation of Akt in human endothelial cells. Circ Res 1998: 83: 334-341.
14. Garcia-Cardena G, Anderson K R, Mauri L, Gimbrone M A. Distinct mechanical stimuli differentially regulate the PI3K/Akt survival pathway in endothelial cells. Ann N Y Acad Sci 2000: 902: 294-297.
15. Yu X, Miyamoto S, Mekada E. Integrin α2β1-dependent EGF receptor activation at cell-cell contact sites. J Cell Sci 2000: 113: 2139-2147.
16. Li C, Xu Q. Mechanical stress-initiated signal transductions in vascular smooth muscle cells. Cell Signal 2000: 12: 435-445.
17. Sharp W W, Simpson D G, Borg T K, Samarel A M, Terracio L. Mechanical forces regulate focal adhesion and costamere assembly in cardiac myocytes. Am J Physiol 1997: 273: H546-H556.
18. Iwasaki H, Eguchi S, Ueno H, Marumo F, Hirata Y. Mechanical stretch stimulates growth of vascular smooth muscle cells via epidermal growth factor receptor. Am J Physiol Heart Circ Physiol 2000: 278: H521-H529.
19. MacKenna D A, Dolfi F, Vuori K, Ruoslahti E. Extracellular signal-regulated kinase and c-jun NH2-terminal kinase activation by mechanical stretch is integrin-dependent and matrix-specific in rat cardiac fibroblasts. J Clin Invest 1998: 101: 301-310.
20. Seko Y, Takahashi N, Tobe K, Kadowaki T, Yazaki Y. Pulsatile stretch activates mitogen-activated protein kinase (MAPK) family members and focal adhesion kinase (p125 (FAK)) in cultured rat cardiac myocytes. Biochem Biophys Res Commun 1999: 259: 8-14.
21. Komuro I, Kudo S, Yamazaki T, Zou Y, Shiojima I, Yazaki Y. Mechanical stretch activates the stress-activated protein kinases in cardiac myocytes. FASEB J 1996: 10: 631-636.
22. Kushida N, Kabuyama Y, Yamaguchi O, Homma Y. Essential role for extracellular Ca(2+) in JNK activation by mechanical stretch in bladder smooth muscle cells. Am J Physiol Cell Physiol 2001: 281: C1165-C1172.
23. Komuro I, Katoh Y, Kaida T, et al. Mechanical loading stimulates cell hypertrophy and specific gene expression in cultured rat cardiac myocytes. Possible role of protein kinase C activation. J Biol Chem 1991: 266: 1265-1268.
24. Sadoshima J, Takahashi T, Jahn L, Izumo S. Roles of mechano-sensitive ion channels, cytoskeleton, and contractive activity in stretch-induced immediate-early gene expression and hypertrophy of cardiac myocytes. Proc Natl Acad Sci USA 1992: 89: 9905-9909.
25. Hishikawa K, Nakaki T, Marumo T, et al. Pressure promotes DNA synthesis in rat cultured vascular smooth muscle cells. J Clin Invest 1994: 93: 1975-1980.
26. Kippenberger S, Bernd A, Loitsch S, et al. Signaling of mechanical stretch in human keratinocytes via MAP kinases. J Invest Dermatol 2000: 114: 408-412.
27. Benzeroual K, Pandey S K, Srivastava A K, van de Werve G, Haddad P S. Insulin-induced Ca(2+) entry in hepatocytes is important for PI 3-kinase activation, but not for insulin receptor and IRS-1 tyrosine phosphorylation. Biochim Biophys Acta 2000: 1495: 14-23.
28. Kosaki K, Ando J, Korenaga R, Kurokawa T, Kamiya A. Fluid shear stress increases the production of granulocyte-macrophage colony-stimulating factor by endothelial cells via mRNA stabilization. Circ Res 1998: 82: 794-802.
29. Ando J, Tsuboi H, Korenaga R, et al. Down-regulation of vascular adhesion molecule-1 by fluid shear stress in cultured mouse endothelial cells. Ann N Y Acad Sci 1995: 748: 148-157.
30. Ando J, Komatsuda T, Kamiya A. Cytoplasmic calcium response to fluid shear stress in cultured vascular endothelial cells. In Vitro Cell Dev Biol 1988: 24: 871-877.
31. Yamamoto K, Korenaga R, Kamiya A, Ando J. Fluid shear stress activates Ca(2+) influx into human endothelial cells via P2X4 purinoceptors. Circ Res 2000: 87: 385-391.
32. Paramio J M, Segrelles C, Ruiz S, Jorcano J L. Inhibition of protein kinase B (PKB) and PKCzeta mediates keratin K10-induced cell cycle arrest. Mol Cell Biol 2001: 21: 7449-7459.
33. Franke T F, Kaplan D R, Cantley L C. PI3K: Downstream AKTion blocks apoptosis. Cell 1997: 88: 435-437.
34. Khwaja A, Rodriguez-Viciana P, Wennstrom S, Warne PH, Downward J. Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. EMBO J 1997: 16: 2783-2793.
35. Kennedy S G, Wagner A J, Conzen S D, et al. The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal. Genes Dev 1997: 11: 701-713.
36. Burgering B M, Coffer P J. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 1995: 376: 599-602.
37. Datta S R, Dudek H, Tao X, et al. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 1997: 91: 231-241.
38. Cardone MH, Roy N, Stennicke H R, et al. Regulation of cell death protease caspase-9 by phosphorylation. Science 1998: 282: 1318-1321.