Integrin α2β1-dependent EGF receptor activation at cell-cell contact sites

Journal of Cell Science

Volumn 113, Issue 12, 2000, Pages 2139-2147

  Yu, Xiaochun ^a,c   Miyamoto, Shingo ^b   Mekada, Eisuke ^a,c  

^a KURUME UNIVERSITY   (Japan)

^b NATIONAL KYUSHU CANCER CENTER   (Japan)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

A431 cell; EGFR; Integrin; Phosphorylation

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; INTEGRIN;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL ADHESION; CELL INTERACTION; CELL LYSATE; CONTROLLED STUDY; CROSS LINKING; DEPHOSPHORYLATION; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

CELL COMMUNICATION; CELL LINE; HUMANS; INTEGRINS; INTERCELLULAR JUNCTIONS; PHOSPHORYLATION; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, COLLAGEN; SIGNAL TRANSDUCTION;

EID: 0033947684     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Berditchevski, F., Zutter, M. M. and Hemler, M. E. (1996). Characterization of novel complexes on the cell surface between integrins and proteins with 4 transmembrane domains (TM4 proteins). Mol Biol. Cell 7, 193-207.
2. Carter, W. G., Wayner. E. A., Bouchard. T. S. and Kaur, P. (1990). The role of integrin α2β1 and α3β1 in cell-cell and cell-substrate adhesion of human epidermal cells. J. Cell Biol. 110, 1387-1404.
3. Clark, E. A. and Brugge, J. S. (1995). Integrins and signal transduction pathways: the road taken. Science 268, 233-239.
4. Couet, J., Sargiacomo, M. and Lisanti, M. P. (1997). Interaction of a receptor tyrosine kinase, EGFR, with Caveolins. J. Biol. Chem. 272, 30429-30438.
5. Cybulsky, A. V., McTavish, A. J. and Cyr, M.-D. (1994). Extracellular matrix modulates epidermal growth factor receptoe activation in rat glomerular epithelial cells. J. Clin. Invest. 94, 68-78.
6. Diamond, M. S., Staunton, D. E., De Fouferolles, A. R., Stacker, S. A., Garcia, A. J., Hibbs, M. L. and Springer, T. A. (1990). ICAM (CD54): a counter-receptor for Mac-1 (CD11/CD18). J. Cell Biol. 111, 3129-3139.
7. Dike, L. and Ingber, D. (1996). Integrin-dependent induction of early growth response genes in capillary endothelial cells. J. Cell Sci. 109, 2855-2863.
8. Elices, M. J., Osborn, L., Takada, Y., Crouse, C., Luhowskyj, S., Hemler, M. E. and Lobb, R. R. (1990). VCAM-1 on activated endothelum interacts with the leukocyto integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site. Cell 60, 577-584.
9. Emlet, D. R., Moscatello, D. K., Ludlow, L. B. and Wong, A. J. (1997). Subsets of epidermal growth factor receptors during activation and endocytosis. J. Biol. Chem. 272, 4079-4086.
10. Fantle, W. J., Johnson, D. E. and Williams, L. T. (1993). Signaling by receptor tyrosine kinases. Annu. Rev. Biochem. 62, 453-481.
11. Frish, S. M. and Ruoslahti, E. (1997). Integrins and anoikis. Curr. Opin. Cell Biol. 9, 701-706.