-
1
-
-
1842330850
-
Biomechanical activation: An emerging paradigm in endothelial adhesion biology
-
Gimbrone MA, Nagel T, Topper JN. Biomechanical activation: an emerging paradigm in endothelial adhesion biology. J Clin Invest. 1997; 99:1809-1813.
-
(1997)
J Clin Invest.
, vol.99
, pp. 1809-1813
-
-
Gimbrone, M.A.1
Nagel, T.2
Topper, J.N.3
-
2
-
-
0030577347
-
Shear stress inhibits apoptosis of human endothelial cells
-
Dimmeler S, Haendeler J, Rippmann V, Nehls M, Zeiher AM. Shear stress inhibits apoptosis of human endothelial cells. FEBS Lett. 1996;399: 71-74.
-
(1996)
FEBS Lett.
, vol.399
, pp. 71-74
-
-
Dimmeler, S.1
Haendeler, J.2
Rippmann, V.3
Nehls, M.4
Zeiher, A.M.5
-
3
-
-
0028040352
-
Molecular aspects of signal transduction of shear stress in the endothelial cell
-
Malek AM, Izumo S. Molecular aspects of signal transduction of shear stress in the endothelial cell. J Hypertens. 1994;12:989-999.
-
(1994)
J Hypertens.
, vol.12
, pp. 989-999
-
-
Malek, A.M.1
Izumo, S.2
-
4
-
-
0029177709
-
Regulation of endothelial cell nitric oxide synthase mRNA expression by shear stress
-
Uematsu M, Ohara Y, Navas JP, Nishida K, Murphy TJ, Alexander RW, Nerem RM, Harrison DG. Regulation of endothelial cell nitric oxide synthase mRNA expression by shear stress. Am J Physiol. 1995;269: C1371-C1375.
-
(1995)
Am J Physiol.
, vol.269
-
-
Uematsu, M.1
Ohara, Y.2
Navas, J.P.3
Nishida, K.4
Murphy, T.J.5
Alexander, R.W.6
Nerem, R.M.7
Harrison, D.G.8
-
5
-
-
0029890099
-
Shear stress modulates expression of Cu/Zn superoxide dismutase in human aortic endothelial cells
-
Inoue N, Ramasamy S, Fukai T, Nerem RM, Harrison DG. Shear stress modulates expression of Cu/Zn superoxide dismutase in human aortic endothelial cells. Circ Res. 1996;79:32-37.
-
(1996)
Circ Res.
, vol.79
, pp. 32-37
-
-
Inoue, N.1
Ramasamy, S.2
Fukai, T.3
Nerem, R.M.4
Harrison, D.G.5
-
6
-
-
0029790770
-
Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: Cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress
-
Topper JN, Cai J, Falb D, Gimbrone MA Jr. Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress. Proc Natl Acad Sci U S A. 1996;93:10417-10422.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 10417-10422
-
-
Topper, J.N.1
Cai, J.2
Falb, D.3
Gimbrone M.A., Jr.4
-
7
-
-
0029741925
-
Fluid flow inhibits endothelial adhesiveness: Nitric oxide and transcriptional regulation of VCAM-1
-
Tsao PS, Buitrago R, Chan JR, Cooke JP. Fluid flow inhibits endothelial adhesiveness: nitric oxide and transcriptional regulation of VCAM-1. Circulation. 1996;94:1682-1689.
-
(1996)
Circulation
, vol.94
, pp. 1682-1689
-
-
Tsao, P.S.1
Buitrago, R.2
Chan, J.R.3
Cooke, J.P.4
-
8
-
-
0028965735
-
Calcium signaling in endothelial cells involves activation of tyrosine kinases and leads to activation of mitogen- Activated protein kinases
-
Fleming I, Fisslthaler B, Busse R. Calcium signaling in endothelial cells involves activation of tyrosine kinases and leads to activation of mitogen- activated protein kinases. Circ Res. 1995;76:522-529.
-
(1995)
Circ Res.
, vol.76
, pp. 522-529
-
-
Fleming, I.1
Fisslthaler, B.2
Busse, R.3
-
9
-
-
0028823506
-
Fluid shear stress stimulates mitogen-activated protein kinase in endothelial cells
-
Tseng H, Peterson T, Berk BC. Fluid shear stress stimulates mitogen-activated protein kinase in endothelial cells. Circ Res. 1995;77:869-878.
-
(1995)
Circ Res.
, vol.77
, pp. 869-878
-
-
Tseng, H.1
Peterson, T.2
Berk, B.C.3
-
10
-
-
0029827580
-
Mitogen-activated protein kinase (ERK1/2) activation by shear stress and adhesion in endothelial cells
-
Takahashi M, Berk BC. Mitogen-activated protein kinase (ERK1/2) activation by shear stress and adhesion in endothelial cells. J Clin Invest. 1996;98:2623-2631.
-
(1996)
J Clin Invest.
, vol.98
, pp. 2623-2631
-
-
Takahashi, M.1
Berk, B.C.2
-
11
-
-
0031031493
-
Differential effect of shear stress on extracellular signal-regulated kinase and N-terminal Jun kinase in endothelial cells
-
Jo H, Sipos K, Go Y-M, Law R, Rong J, McDonald JM. Differential effect of shear stress on extracellular signal-regulated kinase and N-terminal Jun kinase in endothelial cells. J Biol Chem. 1997;272: 1395-1401.
-
(1997)
J Biol Chem.
, vol.272
, pp. 1395-1401
-
-
Jo, H.1
Sipos, K.2
Go, Y.-M.3
Law, R.4
Rong, J.5
McDonald, J.M.6
-
12
-
-
0030729489
-
Fluid shear stress activation of focal adhesion kinase
-
Li S, Kim M, Hu Y-L, Jalali S, Schlaepfer DD, Hunter T, Chien S, Shyy JY-J. Fluid shear stress activation of focal adhesion kinase. J Biol Chem. 1997;272:30455-30462.
-
(1997)
J Biol Chem.
, vol.272
, pp. 30455-30462
-
-
Li, S.1
Kim, M.2
Hu, Y.-L.3
Jalali, S.4
Schlaepfer, D.D.5
Hunter, T.6
Chien, S.7
Shyy, J.Y.-J.8
-
13
-
-
0028898814
-
Shear stress modulates endothelial cell morphology and F-actin organization through the regulation of focal adhesion-associated proteins
-
Girard PR, Nerem RM. Shear stress modulates endothelial cell morphology and F-actin organization through the regulation of focal adhesion-associated proteins. J Cell Physiol. 1995;163:179-193.
-
(1995)
J Cell Physiol.
, vol.163
, pp. 179-193
-
-
Girard, P.R.1
Nerem, R.M.2
-
14
-
-
0030584077
-
The adapter protein Shc couples a class of integrins to the control of cell cycle progression
-
Wary KK, Mainiero F, Isakoff SJ, Marcantonio EE, Giancotti FG. The adapter protein Shc couples a class of integrins to the control of cell cycle progression. Cell. 1996;87:733-743.
-
(1996)
Cell
, vol.87
, pp. 733-743
-
-
Wary, K.K.1
Mainiero, F.2
Isakoff, S.J.3
Marcantonio, E.E.4
Giancotti, F.G.5
-
15
-
-
0030907987
-
PI3K: Downstream AKTion blocks apoptosis
-
Franke TF, Kaplan DR, Cantley LC. PI3K: downstream AKTion blocks apoptosis. Cell. 1997;88:435-437.
-
(1997)
Cell
, vol.88
, pp. 435-437
-
-
Franke, T.F.1
Kaplan, D.R.2
Cantley, L.C.3
-
16
-
-
0030913673
-
Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
-
Khwaja A, Rodriquez-Viciana P, Wennström S, Warne PH, Downward J. Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. EMBO J. 1997;16:2783-2793.
-
(1997)
EMBO J.
, vol.16
, pp. 2783-2793
-
-
Khwaja, A.1
Rodriquez-Viciana, P.2
Wennström, S.3
Warne, P.H.4
Downward, J.5
-
17
-
-
0030904561
-
The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal
-
Kennedy SG, Wagner AJ, Conzen SD, Jordan J, Bellacosa A, Tsichlis PN, Hay N. The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal. Genes Dev. 1997;11:701-713.
-
(1997)
Genes Dev.
, vol.11
, pp. 701-713
-
-
Kennedy, S.G.1
Wagner, A.J.2
Conzen, S.D.3
Jordan, J.4
Bellacosa, A.5
Tsichlis, P.N.6
Hay, N.7
-
18
-
-
0031015986
-
A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin domain
-
Klippel A, Kavanaugh WM, Pot D, Williams LT. A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin domain. Mol Cell Biol. 1997;17:338-344.
-
(1997)
Mol Cell Biol.
, vol.17
, pp. 338-344
-
-
Klippel, A.1
Kavanaugh, W.M.2
Pot, D.3
Williams, L.T.4
-
19
-
-
0029807471
-
Akt is a direct target of the phosphatidylinositol 3-kinase: Activation by growth factors, v-src and v-Ha-ras, in Sf9 and mammalian cells
-
Datta K, Bellacosa A, Chan TO, Tsichlis PN. Akt is a direct target of the phosphatidylinositol 3-kinase: activation by growth factors, v-src and v-Ha-ras, in Sf9 and mammalian cells. J Biol Chem. 1996;271: 30835-30839.
-
(1996)
J Biol Chem.
, vol.271
, pp. 30835-30839
-
-
Datta, K.1
Bellacosa, A.2
Chan, T.O.3
Tsichlis, P.N.4
-
20
-
-
0032578999
-
Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-triphosphate-dependent activation of protein kinase B
-
Stephens L, Anderson K, Stokoe D, Erdjument-Bromage H, Painter GF, Holmes AB, Gaffney PRJ, Reese CB, McCormick F, Tempst P, Coadwell J, Hawkins PT. Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-triphosphate-dependent activation of protein kinase B. Science. 1998;279:710-714.
-
(1998)
Science
, vol.279
, pp. 710-714
-
-
Stephens, L.1
Anderson, K.2
Stokoe, D.3
Erdjument-Bromage, H.4
Painter, G.F.5
Holmes, A.B.6
Gaffney, P.R.J.7
Reese, C.B.8
McCormick, F.9
Tempst, P.10
Coadwell, J.11
Hawkins, P.T.12
-
21
-
-
0032579532
-
Lipid-regulating kinases: Some common themes at last
-
Downward J. Lipid-regulating kinases: some common themes at last. Science. 1998;279:673-674.
-
(1998)
Science
, vol.279
, pp. 673-674
-
-
Downward, J.1
-
22
-
-
0029160069
-
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
-
Burgering BM, Coffer PJ. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature. 1995;376: 599-602.
-
(1995)
Nature
, vol.376
, pp. 599-602
-
-
Burgering, B.M.1
Coffer, P.J.2
-
23
-
-
0029587224
-
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
-
Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature. 1995;378:785-789.
-
(1995)
Nature
, vol.378
, pp. 785-789
-
-
Cross, D.A.1
Alessi, D.R.2
Cohen, P.3
Andjelkovich, M.4
Hemmings, B.A.5
-
24
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
-
Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y, Greenberg ME. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 1997;91:231-241.
-
(1997)
Cell
, vol.91
, pp. 231-241
-
-
Datta, S.R.1
Dudek, H.2
Tao, X.3
Masters, S.4
Fu, H.5
Gotoh, Y.6
Greenberg, M.E.7
-
25
-
-
1842333237
-
Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
-
Peso L, Gonzalez-Garcia M, Page C, Herrera R, Nunez G. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science. 1997;278:687-689.
-
(1997)
Science
, vol.278
, pp. 687-689
-
-
Peso, L.1
Gonzalez-Garcia, M.2
Page, C.3
Herrera, R.4
Nunez, G.5
-
26
-
-
0028916513
-
Nitric oxide synthesis by cultured endothelial cells is modulated by flow conditions
-
Noris M, Morigi M, Donadelli R, Aiello S, Foppolo M, Todeschini M, Orisio S, Remuzzi G, Remuzzi A. Nitric oxide synthesis by cultured endothelial cells is modulated by flow conditions. Circ Res. 1995;76: 536-543.
-
(1995)
Circ Res.
, vol.76
, pp. 536-543
-
-
Noris, M.1
Morigi, M.2
Donadelli, R.3
Aiello, S.4
Foppolo, M.5
Todeschini, M.6
Orisio, S.7
Remuzzi, G.8
Remuzzi, A.9
-
27
-
-
0026698135
-
A simple and rapid method for detection of apoptosis in human cells
-
Rösl F. A simple and rapid method for detection of apoptosis in human cells. Nucleic Acids Res. 1992;20:5243.
-
(1992)
Nucleic Acids Res.
, vol.20
, pp. 5243
-
-
Rösl, F.1
-
28
-
-
0029079275
-
The protein kinase encoded by the Akt protooncogen is a target of the PDGF-activated phosphatidylinositol 3-kinase
-
Franke TF, Yang S-I, Chan TO, Datta K, Kazlauskas A, Morrison DK, Kaplan DR, Tsichlis PN. The protein kinase encoded by the Akt protooncogen is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell. 1995;81:727-736.
-
(1995)
Cell
, vol.81
, pp. 727-736
-
-
Franke, T.F.1
Yang, S.-I.2
Chan, T.O.3
Datta, K.4
Kazlauskas, A.5
Morrison, D.K.6
Kaplan, D.R.7
Tsichlis, P.N.8
-
29
-
-
0027359453
-
Fluid shear stress differentially modulates expression of genes encoding basic fibroblast growth factor and platelet-derived growth factor B chain in vascular endothelium
-
Malek AM, Gibbons GH, Dzau VJ, Izumo S. Fluid shear stress differentially modulates expression of genes encoding basic fibroblast growth factor and platelet-derived growth factor B chain in vascular endothelium. J Clin Invest. 1993;92:2013-2021.
-
(1993)
J Clin Invest.
, vol.92
, pp. 2013-2021
-
-
Malek, A.M.1
Gibbons, G.H.2
Dzau, V.J.3
Izumo, S.4
-
31
-
-
0031044132
-
Integrin signaling transduces shear stress-dependent vasodilation of coronary arterioles
-
Muller JM, Chilian WM, Davies MJ. Integrin signaling transduces shear stress-dependent vasodilation of coronary arterioles. Circ Res. 1997;80: 320-326.
-
(1997)
Circ Res.
, vol.80
, pp. 320-326
-
-
Muller, J.M.1
Chilian, W.M.2
Davies, M.J.3
-
32
-
-
0029118603
-
Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3 kinase
-
Ui M, Okada T, Hazeki K, Hazeki O. Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3 kinase. Trends Biochem Sci. 1995;20:303-307.
-
(1995)
Trends Biochem Sci.
, vol.20
, pp. 303-307
-
-
Ui, M.1
Okada, T.2
Hazeki, K.3
Hazeki, O.4
-
33
-
-
0029965452
-
Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer
-
Wymann MP, Bulgarelli-Leva G, Zvelebil MJ, Pirola L, Vanhaesebroeck B, Waterfield MD, Panayotou G. Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer. Mol Cell Biol. 1996;16:1722-1733.
-
(1996)
Mol Cell Biol.
, vol.16
, pp. 1722-1733
-
-
Wymann, M.P.1
Bulgarelli-Leva, G.2
Zvelebil, M.J.3
Pirola, L.4
Vanhaesebroeck, B.5
Waterfield, M.D.6
Panayotou, G.7
-
34
-
-
0030017263
-
MAP kinase activation by flow in endothelial cells: Role of β1 integrins and tyrosine kinases
-
Ishida T, Peterson TE, Kovach NL, Berk BC. MAP kinase activation by flow in endothelial cells: role of β1 integrins and tyrosine kinases. Circ Res. 1996;79:310-316.
-
(1996)
Circ Res.
, vol.79
, pp. 310-316
-
-
Ishida, T.1
Peterson, T.E.2
Kovach, N.L.3
Berk, B.C.4
-
35
-
-
0345480402
-
Hemodynamic regulation of translation in endothelial cells: Activation of the p70/p85 S6 kinase pathway by fluid shear stress
-
Abstract
-
Kraiss LW, Weyrich AS, Modur V, Alto NM, McIntyre TM, Prescott SM, Zimmerman GA. Hemodynamic regulation of translation in endothelial cells: activation of the p70/p85 S6 kinase pathway by fluid shear stress. Circulation. 1997;96(suppl I):I-263. Abstract.
-
(1997)
Circulation
, vol.96
, Issue.1 SUPPL.
-
-
Kraiss, L.W.1
Weyrich, A.S.2
Modur, V.3
Alto, N.M.4
McIntyre, T.M.5
Prescott, S.M.6
Zimmerman, G.A.7
-
36
-
-
0032578998
-
Phosphorylation and activation of p70S6K by PDK1
-
Pullen N, Dennis PB, Andjelkovic M, Dufner A, Kozman SC, Hemmings BA, Thomas G. Phosphorylation and activation of p70S6K by PDK1. Science. 1998;279:707-710.
-
(1998)
Science
, vol.279
, pp. 707-710
-
-
Pullen, N.1
Dennis, P.B.2
Andjelkovic, M.3
Dufner, A.4
Kozman, S.C.5
Hemmings, B.A.6
Thomas, G.7
|