-
1
-
-
0036683653
-
CCAAT/enhancer -binding proteins: Structure, function and regulation
-
Ramji DP, Foka P. CCAAT/enhancer -binding proteins: Structure, function and regulation. Biochem J 2002; 365:561-75.
-
(2002)
Biochem J
, vol.365
, pp. 561-575
-
-
Ramji, D.P.1
Foka, P.2
-
2
-
-
0031029557
-
Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice
-
USA
-
Zhang DE, Zhang P, Wang ND, Hetherington CJ, Darlington GJ, Tenen DJ. Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice. Proc Natl Acad Sci USA 1997; 94:569-74.
-
(1997)
Proc Natl Acad Sci
, vol.94
, pp. 569-574
-
-
Zhang, D.E.1
Zhang, P.2
Wang, N.D.3
Hetherington, C.J.4
Darlington, G.J.5
Tenen, D.J.6
-
3
-
-
10344230611
-
Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha
-
Zhang P, Iwasaki-Arai J, Iwasaki H, Fenyus ML, Dayaram T, Owens BM, Shigematsu H, Levantini E, Huettner CS, Lekstrom-Kimes JA, Akashi K, Tenen DG. Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha. Immunity 2004; 21:853-63.
-
(2004)
Immunity
, vol.21
, pp. 853-863
-
-
Zhang, P.1
Iwasaki-Arai, J.2
Iwasaki, H.3
Fenyus, M.L.4
Dayaram, T.5
Owens, B.M.6
Shigematsu, H.7
Levantini, E.8
Huettner, C.S.9
Lekstrom-Kimes, J.A.10
Akashi, K.11
Tenen, D.G.12
-
4
-
-
0029024113
-
Lymphoproliferative disorder and unbalanced T-helper response in C/EBPβ-deficient mice
-
Screpanti I, Romani L, Musiani P, Modesti A, Fattori E, Lazzaro D, Sellitto C, Scarpa S, Bellavia D, Lattanzio G, Bistoni F, Frati L, Cortese R, Gulino A, Ciliberto G, Costantini F, Poli V. Lymphoproliferative disorder and unbalanced T-helper response in C/EBPβ-deficient mice. EMBO J 1995; 14:1932-1941.
-
(1995)
EMBO J
, vol.14
, pp. 1932-1941
-
-
Screpanti, I.1
Romani, L.2
Musiani, P.3
Modesti, A.4
Fattori, E.5
Lazzaro, D.6
Sellitto, C.7
Scarpa, S.8
Bellavia, D.9
Lattanzio, G.10
Bistoni, F.11
Frati, L.12
Cortese, R.13
Gulino, A.14
Ciliberto, G.15
Costantini, F.16
Poli, V.17
-
5
-
-
0028853334
-
Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages
-
Tanaka T, Akira S, Yoshida K, Umemoto M, Yoneda Y, Shirafuji N, Fujiwara H, Suematsu S, Yoshida N, Kishimoto T. Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages. Cell 1995; 80:353-62.
-
(1995)
Cell
, vol.80
, pp. 353-362
-
-
Tanaka, T.1
Akira, S.2
Yoshida, K.3
Umemoto, M.4
Yoneda, Y.5
Shirafuji, N.6
Fujiwara, H.7
Suematsu, S.8
Yoshida, N.9
Kishimoto, T.10
-
6
-
-
0037085568
-
Expression of C/EBPβ from the C/EBPα gene locus is sufficient for normal hematopoiesis in vivo
-
Jones LC, Lin ML, Chen SS, Krug V, Hofman WK, Lee S, Lee XH, Koeffler HP. Expression of C/EBPβ from the C/EBPα gene locus is sufficient for normal hematopoiesis in vivo. Blood 2002; 99:2032-6.
-
(2002)
Blood
, vol.99
, pp. 2032-2036
-
-
Jones, L.C.1
Lin, M.L.2
Chen, S.S.3
Krug, V.4
Hofman, W.K.5
Lee, S.6
Lee, X.H.7
Koeffler, H.P.8
-
7
-
-
0033532546
-
Neutrophil-specific granule deficiency results from a novel mutation with loss of function of the transcription factor CCAAT/enhancer binding protein epsilon
-
Lekstrom-Himes JA, Dorman SE, Kopar P, Holland SM, Gallin JI. Neutrophil-specific granule deficiency results from a novel mutation with loss of function of the transcription factor CCAAT/enhancer binding protein epsilon. J Exp Med 1999; 189:1847-52.
-
(1999)
J Exp Med
, vol.189
, pp. 1847-1852
-
-
Lekstrom-Himes, J.A.1
Dorman, S.E.2
Kopar, P.3
Holland, S.M.4
Gallin, J.I.5
-
8
-
-
0035353169
-
Neutrophil-specific granule deficiency: Homozygous recessive inheritance of a frameshift mutation in the gene encoding transcription factor CCAAT/enhancer binding protein-epsilon
-
Gombart AF, Shiohara M, Kwok SH, Agematsu K, Komiyama A, Koeffler HP. Neutrophil-specific granule deficiency: Homozygous recessive inheritance of a frameshift mutation in the gene encoding transcription factor CCAAT/enhancer binding protein-epsilon. Blood 2001; 97:2561-7.
-
(2001)
Blood
, vol.97
, pp. 2561-2567
-
-
Gombart, A.F.1
Shiohara, M.2
Kwok, S.H.3
Agematsu, K.4
Komiyama, A.5
Koeffler, H.P.6
-
9
-
-
0030659176
-
Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein e-deficient mice
-
USA
-
Yamanaka R, Barlow C, Lekstrom-Himes J, Castilla LH, Liu PP, Eckhaus M, Decker T, Wynshaw-Boris A. Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein e-deficient mice. Proc Natl Acad Sci USA 1997; 94:13187-92.
-
(1997)
Proc Natl Acad Sci
, vol.94
, pp. 13187-13192
-
-
Yamanaka, R.1
Barlow, C.2
Lekstrom-Himes, J.3
Castilla, L.H.4
Liu, P.P.5
Eckhaus, M.6
Decker, T.7
Wynshaw-Boris, A.8
-
10
-
-
0037315894
-
Disruption of differentiation in human cancer: AML shows the way
-
Tenen DG. Disruption of differentiation in human cancer: AML shows the way. Nat Rev Cancer 2003; 3:89-101.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 89-101
-
-
Tenen, D.G.1
-
11
-
-
0035093813
-
Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia
-
Pabst T, Mueller BU, Zhang P, Radomska HS, Narravula S, Schnittger S, Behre G, Hiddemann W, Tenen DG. Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia. Nat Genet 2001; 27:263-70.
-
(2001)
Nat Genet
, vol.27
, pp. 263-270
-
-
Pabst, T.1
Mueller, B.U.2
Zhang, P.3
Radomska, H.S.4
Narravula, S.5
Schnittger, S.6
Behre, G.7
Hiddemann, W.8
Tenen, D.G.9
-
12
-
-
0037082508
-
Mutations in the gene encoding the transcription factor CCAAT/enhancer binding protein alpha in myelodysplastic syndromes and acute myeloid leukemias
-
Gombart AF, Hofmann WK, Kawano S, Takeuchi S, Krug U, Kwok SH, Larsen RJ, Asou H, Miller CW, Hoelzer D, et al. Mutations in the gene encoding the transcription factor CCAAT/enhancer binding protein alpha in myelodysplastic syndromes and acute myeloid leukemias. Blood 2002; 99:1332-40.
-
(2002)
Blood
, vol.99
, pp. 1332-1340
-
-
Gombart, A.F.1
Hofmann, W.K.2
Kawano, S.3
Takeuchi, S.4
Krug, U.5
Kwok, S.H.6
Larsen, R.J.7
Asou, H.8
Miller, C.W.9
Hoelzer, D.10
-
13
-
-
0035047652
-
AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia
-
Pabst T, Mueller BU, Harakawa N, Schoch C, Haferlach T, Behre G, Hiddemann W, Zhang DE, Tenen DG. AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia. Nat Med 2001; 7:444-51.
-
(2001)
Nat Med
, vol.7
, pp. 444-451
-
-
Pabst, T.1
Mueller, B.U.2
Harakawa, N.3
Schoch, C.4
Haferlach, T.5
Behre, G.6
Hiddemann, W.7
Zhang, D.E.8
Tenen, D.G.9
-
14
-
-
1442307974
-
Internal tandem duplication mutation of FLT3 blocks myeloid differentiation through suppression of C/EBPα expression
-
Zheng R, Friedman AD, Levis M, Li L, Weir EG, Small D. Internal tandem duplication mutation of FLT3 blocks myeloid differentiation through suppression of C/EBPα expression. Blood 2004; 103:1883-90.
-
(2004)
Blood
, vol.103
, pp. 1883-1890
-
-
Zheng, R.1
Friedman, A.D.2
Levis, M.3
Li, L.4
Weir, E.G.5
Small, D.6
-
15
-
-
33344455424
-
Block of C/EBPα function by phosphorylation in acute myeloid leukemia with FLT3 activating mutations
-
In press
-
Radomska HS, Bassères DS, Zheng R, Zhang P, Dayaram T, Yamamoto Y, Sternberg DW, Lokker N, Giese NA, Bohlander SK, Schnittger S, Delmotte MH, Davis RJ, Small D, Hiddemann W, Gilliland DG, Tenen DG. Block of C/EBPα function by phosphorylation in acute myeloid leukemia with FLT3 activating mutations. J Exp Med 2006; In press.
-
(2006)
J Exp Med
-
-
Radomska, H.S.1
Bassères, D.S.2
Zheng, R.3
Zhang, P.4
Dayaram, T.5
Yamamoto, Y.6
Sternberg, D.W.7
Lokker, N.8
Giese, N.A.9
Bohlander, S.K.10
Schnittger, S.11
Delmotte, M.H.12
Davis, R.J.13
Small, D.14
Hiddemann, W.15
Gilliland, D.G.16
Tenen, D.G.17
-
16
-
-
0036340784
-
BCR-ABL suppresses C/EBPalpha expression through inhibitory action of hnRNP E2
-
Perrotti D, Cesi V, Trotta R, Guerzoni C, Santilli G, Campbell K, Iervolino A, Condorelli F, Gambacorti-Passerini C, Caligiuri MA, Calabretta B. BCR-ABL suppresses C/EBPalpha expression through inhibitory action of hnRNP E2. Nat Genet 2002; 30:48-58.
-
(2002)
Nat Genet
, vol.30
, pp. 48-58
-
-
Perrotti, D.1
Cesi, V.2
Trotta, R.3
Guerzoni, C.4
Santilli, G.5
Campbell, K.6
Iervolino, A.7
Condorelli, F.8
Gambacorti-Passerini, C.9
Ma, C.10
Calabretta, B.11
-
17
-
-
0347362803
-
Restoration of C/EBPalpha expression in a BCR-ABL+ cell line induces terminal granulocytic differentiation
-
Tavor S, Park DJ, Gery S, Vuong PT, Gombart AF, Koeffler HP. Restoration of C/EBPalpha expression in a BCR-ABL+ cell line induces terminal granulocytic differentiation. J Biol Chem 2003; 278:52651-9.
-
(2003)
J Biol Chem
, vol.278
, pp. 52651-52659
-
-
Tavor, S.1
Park, D.J.2
Gery, S.3
Vuong, P.T.4
Gombart, A.F.5
Koeffler, H.P.6
-
18
-
-
33646423409
-
Inducible activation of C/EBPβ, a gene negatively regulated by BCR/ABL, inhibits proliferation and promotes differentiation of BCR/ABL-expressing cells
-
In press
-
Guerzoni C, Bardini M, Mariani SA, Ferrari-Amorotti G, Neviani P, Panno ML, Zhang Y, Martinez R, Perrotti D, Calabretta D. Inducible activation of C/EBPβ, a gene negatively regulated by BCR/ABL, inhibits proliferation and promotes differentiation of BCR/ABL-expressing cells. Blood 2006; In press.
-
(2006)
Blood
-
-
Guerzoni, C.1
Bardini, M.2
Mariani, S.A.3
Ferrari-Amorotti, G.4
Neviani, P.5
Panno, M.L.6
Zhang, Y.7
Martinez, R.8
Perrotti, D.9
Calabretta, D.10
-
19
-
-
0025936177
-
A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA
-
Descombes P, Schibler V. A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA. Cell 1991; 67:569-79.
-
(1991)
Cell
, vol.67
, pp. 569-579
-
-
Descombes, P.1
Schibler, V.2
-
20
-
-
0033869876
-
Translational control of C/EBPα and C/EBPβ isoforms expression
-
Calkhoven CF, Muller C, Leutz A. Translational control of C/EBPα and C/EBPβ isoforms expression. Genes and Dev 2000; 14:1920-32.
-
(2000)
Genes and Dev
, vol.14
, pp. 1920-1932
-
-
Calkhoven, C.F.1
Muller, C.2
Leutz, A.3
-
21
-
-
0034741622
-
Characterization of C/EBPβ isoforms in normal versus neoplastic mammary epithelial cells
-
Eaton EM, Hanlon M, Bundy L, Sealy L. Characterization of C/EBPβ isoforms in normal versus neoplastic mammary epithelial cells. J Cell Physiol 2001; 189:91-105.
-
(2001)
J Cell Physiol
, vol.189
, pp. 91-105
-
-
Eaton, E.M.1
Hanlon, M.2
Bundy, L.3
Sealy, L.4
-
22
-
-
0035138818
-
A role for CCAAT/enhancer binding protein beta - Liver enriched inhibitory protein in mammary epithelial cell proliferation
-
Zahnow CA, Cardiff RD, Laucirica R, Medina D, Rosen JM. A role for CCAAT/enhancer binding protein beta - Liver enriched inhibitory protein in mammary epithelial cell proliferation. Cancer Res 2001; 61:261-9.
-
(2001)
Cancer Res
, vol.61
, pp. 261-269
-
-
Zahnow, C.A.1
Cardiff, R.D.2
Laucirica, R.3
Medina, D.4
Rosen, J.M.5
-
23
-
-
4043054440
-
C/EBPβ isoforms LIP and LAP modulate progression of the cell cycle in the regenerating mouse liver
-
Leudde T, Duderstadt M, Streetz KL, Tacke F, Kubieka S, Manns MP, Trautwein C. C/EBPβ isoforms LIP and LAP modulate progression of the cell cycle in the regenerating mouse liver. Hepatology 2004; 40:356-65.
-
(2004)
Hepatology
, vol.40
, pp. 356-365
-
-
Leudde, T.1
Duderstadt, M.2
Streetz, K.L.3
Tacke, F.4
Kubieka, S.5
Manns, M.P.6
Trautwein, C.7
-
24
-
-
0346458703
-
Dominant-negative C/EBP disrupts mitotic clonal expansion and differentiation of 3T3-L1 preadipocytes
-
USA
-
Zhang JW, Tang RR, Vinson C, Lane MD. Dominant-negative C/EBP disrupts mitotic clonal expansion and differentiation of 3T3-L1 preadipocytes. Proc Natl Acad Sci USA 2004; 101:43-7.
-
(2004)
Proc Natl Acad Sci
, vol.101
, pp. 43-47
-
-
Zhang, J.W.1
Tang, R.R.2
Vinson, C.3
Lane, M.D.4
-
25
-
-
4644354051
-
A new role for C/EBPbeta in acute promyelocytic leukemia
-
Duprez E. A new role for C/EBPbeta in acute promyelocytic leukemia. Cell Cycle 2004; 3:389-90.
-
(2004)
Cell Cycle
, vol.3
, pp. 389-390
-
-
Duprez, E.1
-
26
-
-
0037438380
-
The effect of BCR/ABL on C/EBP transcription factor regulation and neutrophilic differentiation are reversed by the Abl Kinase inhibitor imatinib mesylate
-
Schuster C, Forster K, Dierks H, Elsässer A, Behre G, Simon H, Danhauser-Riedl S, Hallek M, Warmuth M. The effect of BCR/ABL on C/EBP transcription factor regulation and neutrophilic differentiation are reversed by the Abl Kinase inhibitor imatinib mesylate. Blood 2003; 101:655-63.
-
(2003)
Blood
, vol.101
, pp. 655-663
-
-
Schuster, C.1
Forster, K.2
Dierks, H.3
Elsässer, A.4
Behre, G.5
Simon, H.6
Danhauser-Riedl, S.7
Hallek, M.8
Warmuth, M.9
-
27
-
-
33745161658
-
Leukemogenesis induced by wild type and STI571-resistant BCR/ABL is potently suppressed by C/EBPα
-
Ferrari-Amorotti G, Keeshan K, Zattoni M, Guerzoni C, Cattelani S, Donato NJ, Calabretta B. Leukemogenesis induced by wild type and STI571-resistant BCR/ABL is potently suppressed by C/EBPα. Blood 2006; In press.
-
(2006)
Blood
-
-
Ferrari-Amorotti, G.1
Keeshan, K.2
Zattoni, M.3
Guerzoni, C.4
Cattelani, S.5
Donato, N.J.6
Calabretta, B.7
-
28
-
-
0034740215
-
C/EBPalpha arrests cell proliferation through direct inhibition of Cdk2 and Cdk4
-
Wang H, Iakova P, Wilde M, Welm A, Goode T, Roesler WJ, Timchenko NA. C/EBPalpha arrests cell proliferation through direct inhibition of Cdk2 and Cdk4. Mol Cell 2001; 8:817-28.
-
(2001)
Mol Cell
, vol.8
, pp. 817-828
-
-
Wang, H.1
Iakova, P.2
Wilde, M.3
Welm, A.4
Goode, T.5
Roesler, W.J.6
Timchenko, N.A.7
-
29
-
-
0035913913
-
E2F repression by C/EBPα is required for adipogenesis and granulopoiesis in vivo
-
Porse BT, Pedersen T, Xu X, Lindberg B, Wewer UM, Friis-Hansen L, Nerlov C. E2F repression by C/EBPα is required for adipogenesis and granulopoiesis in vivo. Cell 2001; 107:247-58.
-
(2001)
Cell
, vol.107
, pp. 247-258
-
-
Porse, B.T.1
Pedersen, T.2
Xu, X.3
Lindberg, B.4
Wewer, U.M.5
Friis-Hansen, L.6
Nerlov, C.7
-
30
-
-
1342346543
-
The CCAAT enhancer-binding protein alpha (C/EBPalpha) requires a SWI/SNF complex for proliferation arrest
-
Muller C, Calkhoven CF, Sha X, Leutz A. The CCAAT enhancer-binding protein alpha (C/EBPalpha) requires a SWI/SNF complex for proliferation arrest. J Biol Chem 2004; 279:7353-8.
-
(2004)
J Biol Chem
, vol.279
, pp. 7353-7358
-
-
Muller, C.1
Calkhoven, C.F.2
Sha, X.3
Leutz, A.4
-
31
-
-
0041737609
-
The transcription activation function of C/EBPα is required for induction of granulocytic differentiation
-
Keeshan K, Santilli G, Corradini F, Pernotti D, Calabretta B. The transcription activation function of C/EBPα is required for induction of granulocytic differentiation. Blood 2003; 102:1267-75.
-
(2003)
Blood
, vol.102
, pp. 1267-1275
-
-
Keeshan, K.1
Santilli, G.2
Corradini, F.3
Pernotti, D.4
Calabretta, B.5
-
32
-
-
0028979308
-
CRP2 (C/EBPβ) contains a bipartite regulatory domain that controls transcriptional activation, DNA binding and cell specificity
-
Williams SC, Baer M, Dillner AJ, Johnson PF. CRP2 (C/EBPβ) contains a bipartite regulatory domain that controls transcriptional activation, DNA binding and cell specificity. EMBO J 1995; 14:3170-83.
-
(1995)
EMBO J
, vol.14
, pp. 3170-3183
-
-
Williams, S.C.1
Baer, M.2
Dillner, A.J.3
Johnson, P.F.4
-
33
-
-
0037039312
-
CCAAT/enhancer binding protein-beta is a mediator of keratinocyte survival and skin tumorigenesis involving oncogenic Ras signaling
-
USA
-
Zhu S, Yoon K, Sterneck E, Johnson PF, Smart RC. CCAAT/enhancer binding protein-beta is a mediator of keratinocyte survival and skin tumorigenesis involving oncogenic Ras signaling. Proc Natl Acad Sci USA 2002; 99:207-12.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 207-212
-
-
Zhu, S.1
Yoon, K.2
Sterneck, E.3
Johnson, P.F.4
Smart, R.C.5
-
34
-
-
0344604528
-
Genomic instability in Gadd45 a-deficient mice
-
Hollander MC, Sheikh MS, Bulavin DV, Lundgren K, Augeri-Henmueller L, Shehee R, Molinaro TA, Kim KE, Tolosa E, Ashwell JD, Rosenberg MP, Zhan Q, Fernandez-Salguero PM, Morgan WF, Deng CX, Fornace Jr AJ. Genomic instability in Gadd45 a-deficient mice. Nat Genet 1999; 23:176-84.
-
(1999)
Nat Genet
, vol.23
, pp. 176-184
-
-
Hollander, M.C.1
Sheikh, M.S.2
Bulavin, D.V.3
Lundgren, K.4
Augeri-Henmueller, L.5
Shehee, R.6
Molinaro, T.A.7
Kim, K.E.8
Tolosa, E.9
Ashwell, J.D.10
Rosenberg, M.P.11
Zhan, Q.12
Fernandez-Salguero, P.M.13
Morgan, W.F.14
Deng, C.X.15
Fornace Jr., A.J.16
-
36
-
-
0033616501
-
GADD45 induction of a G2/M cell cycle checkpoint
-
USA
-
Wang XW, Zhan Q, Coursen JD, Khan MA, Kortny HU, Yu L, Hollander MC, O'Connor PM, Fornace Jr AJ, Harris CC. GADD45 induction of a G2/M cell cycle checkpoint. Proc Natl Acad Sci USA 1999; 96:3706-11.
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 3706-3711
-
-
Wang, X.W.1
Zhan, Q.2
Coursen, J.D.3
Khan, M.A.4
Kortny, H.U.5
Yu, L.6
Hollander, M.C.7
O'Connor, P.M.8
Fornace Jr., A.J.9
Harris, C.C.10
-
37
-
-
4644354051
-
A new role for C/EBPbeta in acute promyelocytic leukemia
-
Duprez E. A new role for C/EBPbeta in acute promyelocytic leukemia. Cell Cycle 2004; 3:389-90.
-
(2004)
Cell Cycle
, vol.3
, pp. 389-390
-
-
Duprez, E.1
|