-
1
-
-
0015694748
-
A new consistent chromosomal abnormality in chronic myelogenous leukemia identified by quinacrine fluorescence and Giemsa staining
-
Rowley J. A new consistent chromosomal abnormality in chronic myelogenous leukemia identified by quinacrine fluorescence and Giemsa staining. Nature. 1973;243:290-293.
-
(1973)
Nature
, vol.243
, pp. 290-293
-
-
Rowley, J.1
-
2
-
-
0033565561
-
The biology of chronic myeloid leukemia
-
Faderl S, Talpaz M, Estrov Z, O'Brien S, Kurzrock R, Kantarjian HM. The biology of chronic myeloid leukemia. N Engl J Med. 1999;341:164-172.
-
(1999)
N Engl J Med
, vol.341
, pp. 164-172
-
-
Faderl, S.1
Talpaz, M.2
Estrov, Z.3
O'Brien, S.4
Kurzrock, R.5
Kantarjian, H.M.6
-
3
-
-
0034121993
-
Expression of the NUP98/HOXA9 fusion transcript in the blast crisis of Philadelphia chromosome-positive chronic myelogenous leukaemia with t(7;11)(p15;p15)
-
Yamamoto K, Nakamura Y, Saito K, Furusawa S. Expression of the NUP98/HOXA9 fusion transcript in the blast crisis of Philadelphia chromosome-positive chronic myelogenous leukaemia with t(7;11)(p15;p15). Br J Haematol. 2000;109:423-426.
-
(2000)
Br J Haematol
, vol.109
, pp. 423-426
-
-
Yamamoto, K.1
Nakamura, Y.2
Saito, K.3
Furusawa, S.4
-
4
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
-
Druker BJ, Tamura S, Buchdunger E, et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med. 1996;2:561-566.
-
(1996)
Nat Med
, vol.2
, pp. 561-566
-
-
Druker, B.J.1
Tamura, S.2
Buchdunger, E.3
-
5
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
Druker BJ, Talpaz M, Resta DJ, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med. 2001;344:1031-1037.
-
(2001)
N Engl J Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
-
6
-
-
0037186915
-
Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia
-
Kantarjian H, Sawyers C, Hochhaus A, et al. Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia. N Engl J Med. 2002;346:645-652.
-
(2002)
N Engl J Med
, vol.346
, pp. 645-652
-
-
Kantarjian, H.1
Sawyers, C.2
Hochhaus, A.3
-
7
-
-
0035810142
-
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
-
Druker BJ, Sawyers CL, Kantarjian H, et al. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med. 2001;344:1038-1042.
-
(2001)
N Engl J Med
, vol.344
, pp. 1038-1042
-
-
Druker, B.J.1
Sawyers, C.L.2
Kantarjian, H.3
-
8
-
-
0035800507
-
Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
-
Gorre ME, Mohammed M, Ellwood K, et al. Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science. 2001;293:876-880.
-
(2001)
Science
, vol.293
, pp. 876-880
-
-
Gorre, M.E.1
Mohammed, M.2
Ellwood, K.3
-
9
-
-
0030854907
-
Transcription factors, normal myeloid development, and leukemia
-
Tenen DG, Hromas R, Licht JD, Zhang DE. Transcription factors, normal myeloid development, and leukemia. Blood. 1997;90:489-519.
-
(1997)
Blood
, vol.90
, pp. 489-519
-
-
Tenen, D.G.1
Hromas, R.2
Licht, J.D.3
Zhang, D.E.4
-
10
-
-
0034130509
-
Regulation of granulopoiesis by transcription factors and cytokine signals
-
Ward AC, Loeb DM, Soede-Bobok AA, Touw IP, Friedman AD. Regulation of granulopoiesis by transcription factors and cytokine signals. Leukemia. 2000;14:973-990.
-
(2000)
Leukemia
, vol.14
, pp. 973-990
-
-
Ward, A.C.1
Loeb, D.M.2
Soede-Bobok, A.A.3
Touw, I.P.4
Friedman, A.D.5
-
11
-
-
0028000668
-
Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization
-
Lieschke GJ, Grail D, Hodgson G, et al. Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization. Blood. 1994;84:1737-1746.
-
(1994)
Blood
, vol.84
, pp. 1737-1746
-
-
Lieschke, G.J.1
Grail, D.2
Hodgson, G.3
-
12
-
-
0030292823
-
Impaired production and increased apoptosis of neutrophils in granulocyte colony-stimulating factor receptor-deficient mice
-
Liu F, Wu HY, Wesselschmidt R, Kornaga T, Link DC. Impaired production and increased apoptosis of neutrophils in granulocyte colony-stimulating factor receptor-deficient mice. Immunity. 1996;5:491-501.
-
(1996)
Immunity
, vol.5
, pp. 491-501
-
-
Liu, F.1
Wu, H.Y.2
Wesselschmidt, R.3
Kornaga, T.4
Link, D.C.5
-
13
-
-
0031029557
-
Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice
-
Zhang DE, Zhang P, Wang ND, Hetherington CJ, Darlington GJ, Tenen DG. Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice. Proc Natl Acad Sci U S A. 1997;94:569-574.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 569-574
-
-
Zhang, D.E.1
Zhang, P.2
Wang, N.D.3
Hetherington, C.J.4
Darlington, G.J.5
Tenen, D.G.6
-
14
-
-
0033564978
-
C/EBPalpha bypasses granulocyte colony-stimulating factor signals to rapidly induce PU.1 gene expression, stimulate granulocytic differentiation, and limit proliferation in 32D cl3 myeloblasts
-
Wang X, Scott E, Sawyers CL, Friedman AD. C/EBPalpha bypasses granulocyte colony-stimulating factor signals to rapidly induce PU.1 gene expression, stimulate granulocytic differentiation, and limit proliferation in 32D cl3 myeloblasts. Blood. 1999;94:560-571.
-
(1999)
Blood
, vol.94
, pp. 560-571
-
-
Wang, X.1
Scott, E.2
Sawyers, C.L.3
Friedman, A.D.4
-
15
-
-
0030659176
-
Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice
-
Yamanaka R, Barlow C, Lekstrom-Himes J, et al. Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice. Proc Natl Acad Sci U S A. 1997;94:13187-13192.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 13187-13192
-
-
Yamanaka, R.1
Barlow, C.2
Lekstrom-Himes, J.3
-
16
-
-
0026758202
-
A novel temporal expression pattern of three C/EBP family members in differentiating myelomonocytic cells
-
Scott LM, Civin CI, Rorth P, Friedman AD. A novel temporal expression pattern of three C/EBP family members in differentiating myelomonocytic cells. Blood. 1992;80:1725-1735.
-
(1992)
Blood
, vol.80
, pp. 1725-1735
-
-
Scott, L.M.1
Civin, C.I.2
Rorth, P.3
Friedman, A.D.4
-
17
-
-
0035883084
-
Granulocyte colony-stimulating factor regulates myeloid differentiation through CCAAT/enhancer-binding protein epsilon
-
Nakajima H, Ihle JN. Granulocyte colony-stimulating factor regulates myeloid differentiation through CCAAT/enhancer-binding protein epsilon. Blood. 2001;98:897-905.
-
(2001)
Blood
, vol.98
, pp. 897-905
-
-
Nakajima, H.1
Ihle, J.N.2
-
18
-
-
0032479980
-
TLS/FUS, a pro-oncogene involved in multiple chromosomal translocations, is a novel regulator of BCR/ABL-mediated leukemogenesis
-
Perrotti D, Bonatti S, Trotta R, et al. TLS/FUS, a pro-oncogene involved in multiple chromosomal translocations, is a novel regulator of BCR/ABL-mediated leukemogenesis. EMBO J. 1998;17:4442-4455.
-
(1998)
EMBO J
, vol.17
, pp. 4442-4455
-
-
Perrotti, D.1
Bonatti, S.2
Trotta, R.3
-
19
-
-
0031455168
-
The Src family kinase Hck interacts with Bcr-Abl by a kinase-independent mechanism and phosphorylates the Grb2-binding site of Bcr
-
Warmuth M, Bergmann M, Priess A, Häuslmann K, Emmerich B, Hallek M. The Src family kinase Hck interacts with Bcr-Abl by a kinase-independent mechanism and phosphorylates the Grb2-binding site of Bcr. J Biol Chem. 1997;272:33260-33270.
-
(1997)
J Biol Chem
, vol.272
, pp. 33260-33270
-
-
Warmuth, M.1
Bergmann, M.2
Priess, A.3
Häuslmann, K.4
Emmerich, B.5
Hallek, M.6
-
20
-
-
0037438513
-
Dual-specific Src and Abl kinase inhibitors, PP1 and CGP76030, inhibit growth and survival of cells expressing imatinib mesylate-resistant Bcr-Abl kinases
-
Warmuth M, Simon N, Mitina O, et al. Dual-specific Src and Abl kinase inhibitors, PP1 and CGP76030, inhibit growth and survival of cells expressing imatinib mesylate-resistant Bcr-Abl kinases. Blood. 2003;101:664-672.
-
(2003)
Blood
, vol.101
, pp. 664-672
-
-
Warmuth, M.1
Simon, N.2
Mitina, O.3
-
21
-
-
0035760308
-
Notch1 inhibits differentiation of hematopoietic cells by sustaining GATA-2 expression
-
Kumano K, Chiba S, Shimizu K, et al. Notch1 inhibits differentiation of hematopoietic cells by sustaining GATA-2 expression. Blood. 2001;98:3283-3289.
-
(2001)
Blood
, vol.98
, pp. 3283-3289
-
-
Kumano, K.1
Chiba, S.2
Shimizu, K.3
-
22
-
-
0036340784
-
BCR-ABL suppresses C/EBPalpha expression through inhibitory action of hnRNP E2
-
Perrotti D, Cesi V, Trotta R, et al. BCR-ABL suppresses C/EBPalpha expression through inhibitory action of hnRNP E2. Nat Genet. 2002;30:48-58.
-
(2002)
Nat Genet
, vol.30
, pp. 48-58
-
-
Perrotti, D.1
Cesi, V.2
Trotta, R.3
-
23
-
-
0023182058
-
Cytokine-dependent granulocytic differentiation: Regulation of proliferative and differentiative responses in a murine progenitor cell line
-
Valtieri M, Tweardy DJ, Caracciolo D, et al. Cytokine-dependent granulocytic differentiation: regulation of proliferative and differentiative responses in a murine progenitor cell line. J Immunol. 1987;138:3829-3835.
-
(1987)
J Immunol
, vol.138
, pp. 3829-3835
-
-
Valtieri, M.1
Tweardy, D.J.2
Caracciolo, D.3
-
24
-
-
0035005526
-
c-Myc is a critical target for c/EBPalpha in granulopoiesis
-
Johansen LM, Iwama A, Lodie TA, et al. c-Myc is a critical target for c/EBPalpha in granulopoiesis. Mol Cell Biol. 2001;21:3789-3806.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3789-3806
-
-
Johansen, L.M.1
Iwama, A.2
Lodie, T.A.3
-
25
-
-
0028047591
-
Granulocyte colony-stimulating factor receptor mRNA upregulation is an immediate early marker of myeloid differentiation and exhibits dysfunctional regulation in leukemic cells
-
Steinman RA, Tweardy DJ. Granulocyte colony-stimulating factor receptor mRNA upregulation is an immediate early marker of myeloid differentiation and exhibits dysfunctional regulation in leukemic cells. Blood. 1994;83:119-127.
-
(1994)
Blood
, vol.83
, pp. 119-127
-
-
Steinman, R.A.1
Tweardy, D.J.2
-
26
-
-
0029793902
-
PU.1 (Spi-1) and C/EBP alpha regulate the granulocyte colony-stimulating factor receptor promoter in myeloid cells
-
Smith LT, Hohaus S, Gonzalez DA, Dziennis SE, Tenen DG. PU.1 (Spi-1) and C/EBP alpha regulate the granulocyte colony-stimulating factor receptor promoter in myeloid cells. Blood. 1996;88:1234-1247.
-
(1996)
Blood
, vol.88
, pp. 1234-1247
-
-
Smith, L.T.1
Hohaus, S.2
Gonzalez, D.A.3
Dziennis, S.E.4
Tenen, D.G.5
-
27
-
-
0033552927
-
Expression of BCR-ABL in M1 myeloid leukemia cells induces differentiation without arresting proliferation
-
Cambier N, Zhang Y, Vairo G, et al. Expression of BCR-ABL in M1 myeloid leukemia cells induces differentiation without arresting proliferation. Oncogene. 1999;18:343-352.
-
(1999)
Oncogene
, vol.18
, pp. 343-352
-
-
Cambier, N.1
Zhang, Y.2
Vairo, G.3
-
28
-
-
0034652159
-
Regulated expression of P210 Bcr-Abl during embryonic stem cell differentiation stimulates multipotential progenitor expansion and myeloid cell fate
-
Era T, Witte ON. Regulated expression of P210 Bcr-Abl during embryonic stem cell differentiation stimulates multipotential progenitor expansion and myeloid cell fate. Proc Natl Acad Sci U S A. 2000;97:1737-1742.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 1737-1742
-
-
Era, T.1
Witte, O.N.2
-
29
-
-
0035047652
-
AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia
-
Pabst T, Mueller BU, Harakawa N, et al. AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia. Nat Med. 2001;7:444-451.
-
(2001)
Nat Med
, vol.7
, pp. 444-451
-
-
Pabst, T.1
Mueller, B.U.2
Harakawa, N.3
-
30
-
-
0035093813
-
Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia
-
Pabst T, Mueller BU, Zhang P, et al. Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia. Nat Genet. 2001;27:263-270.
-
(2001)
Nat Genet
, vol.27
, pp. 263-270
-
-
Pabst, T.1
Mueller, B.U.2
Zhang, P.3
-
31
-
-
0037089322
-
CCAAT/enhancer-binding proteins are required for granulopoiesis independent of their induction of the granulocyte colony-stimulating factor receptor
-
Wang QF, Friedman AD. CCAAT/enhancer-binding proteins are required for granulopoiesis independent of their induction of the granulocyte colony-stimulating factor receptor. Blood. 2002;99:2776-2785.
-
(2002)
Blood
, vol.99
, pp. 2776-2785
-
-
Wang, Q.F.1
Friedman, A.D.2
-
32
-
-
0029908547
-
A novel function for Myc: Inhibition of C/EBP-dependent gene activation
-
Mink S, Mutschler B, Weiskirchen R, Bister K, Klempnauer KH. A novel function for Myc: inhibition of C/EBP-dependent gene activation. Proc Natl Acad Sci U S A. 1996;93:6635-6640.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 6635-6640
-
-
Mink, S.1
Mutschler, B.2
Weiskirchen, R.3
Bister, K.4
Klempnauer, K.H.5
-
33
-
-
0035889155
-
Multipotent hematopoietic cell lines derived from C/EBPalpha(-/-) knockout mice display granulocyte macrophage-colony-stimulating factor, granulocyte-colony-stimulating factor, and retinoic acid-induced granulocytic differentiation
-
Collins SJ, Ulmer J, Purton LE, Darlington G. Multipotent hematopoietic cell lines derived from C/EBPalpha(-/-) knockout mice display granulocyte macrophage-colony-stimulating factor, granulocyte-colony-stimulating factor, and retinoic acid-induced granulocytic differentiation. Blood. 2001;98:2382-2388.
-
(2001)
Blood
, vol.98
, pp. 2382-2388
-
-
Collins, S.J.1
Ulmer, J.2
Purton, L.E.3
Darlington, G.4
-
35
-
-
0034746508
-
C/EBPepsilon -/- mice: Increased rate of myeloid proliferation and apoptosis
-
Verbeek W, Wachter M, Lekstrom-Himes J, Koeftier HP. C/EBPepsilon -/- mice: increased rate of myeloid proliferation and apoptosis. Leukemia. 2001;15:103-111.
-
(2001)
Leukemia
, vol.15
, pp. 103-111
-
-
Verbeek, W.1
Wachter, M.2
Lekstrom-Himes, J.3
Koeftier, H.P.4
-
36
-
-
0035800776
-
CCAAT/enhancer-binding protein-alpha cooperates with p21 to inhibit cyclin-dependent kinase-2 activity and induces growth arrest independent of DNA binding
-
Harris TE, Albrecht JH, Nakanishi M, Darlington GJ. CCAAT/enhancer-binding protein-alpha cooperates with p21 to inhibit cyclin-dependent kinase-2 activity and induces growth arrest independent of DNA binding. J Biol Chem. 2001;276:29200-29209.
-
(2001)
J Biol Chem
, vol.276
, pp. 29200-29209
-
-
Harris, T.E.1
Albrecht, J.H.2
Nakanishi, M.3
Darlington, G.J.4
-
37
-
-
0034740215
-
C/EBPalpha arrests cell proliferation through direct inhibition of Cdk2 and Cdk4
-
Wang H, lakova P, Wilde M, et al. C/EBPalpha arrests cell proliferation through direct inhibition of Cdk2 and Cdk4. Mol Cell. 2001;8:817-828.
-
(2001)
Mol Cell
, vol.8
, pp. 817-828
-
-
Wang, H.1
Lakova, P.2
Wilde, M.3
-
38
-
-
0036500652
-
C/EBPalpha triggers proteasome-dependent degradation of cdk4 during growth arrest
-
Wang H, Goode T, Iakova P, Albrecht JH, Timchenko NA. C/EBPalpha triggers proteasome-dependent degradation of cdk4 during growth arrest. EMBO J. 2002;21:930-941.
-
(2002)
EMBO J
, vol.21
, pp. 930-941
-
-
Wang, H.1
Goode, T.2
Iakova, P.3
Albrecht, J.H.4
Timchenko, N.A.5
|