DY-9760e, a novel calmodulin antagonist with cytoprotective action

European Journal of Pharmacology

Volumn 336, Issue 1, 1997, Pages 99-106

  Sugimura, Masunobu ^a   Sato, Toshiyuki ^a   Nakayama, Wakako ^a   Morishima, Yoshiyuki ^a   Fukunaga, Koji ^b   Omitsu, Masao ^b   Miyamoto, Eishichi ^b   Shirasaki, Yasufumi ^a  

^a DAIICHI SANKYO CO   (Japan)

^b KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

Calmodulin antagonist; Cytotoxicity; DY 9760e; Neuroprotection; W7

Indexed keywords

3 [2 [4 (3 CHLORO 2 METHYLPHENYL) 1 PIPERAZINYL]ETHYL] 5,6 DIMETHOXY-1-(4 -IMIDAZOLYLMETHYL) 1H INDAZOLE DIHYDROCHLORIDE 3.5 HYDRATE; CALMODULIN; CALMODULIN INHIBITOR; CALPAIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; DY 9760E; MYOSIN LIGHT CHAIN KINASE; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE; PHOSPHODIESTERASE; PROTEIN KINASE C; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL PROTECTION; CONTROLLED STUDY; DRUG BINDING; ENZYME INHIBITION; IN VITRO STUDY; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL;

CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALCIMYCIN; CALCINEURIN; CALCIUM; CALMODULIN; CELL DEATH; INDAZOLES; IONOPHORES; NEUROBLASTOMA; SULFONAMIDES; TUMOR CELLS, CULTURED;

EID: 0030732695     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01251-X     Document Type: Article

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