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Volumn 97, Issue 6, 2006, Pages 1690-1699

The genetics of neurodegenerative diseases

Author keywords

synuclein; Ataxia; Dementia; Parkinsonism; Polyglutamine; Tau

Indexed keywords

ATAXIN 1; ATAXIN 3; POLYGLUTAMINE; SYNUCLEIN; UBIQUITIN;

EID: 33745018376     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.03979.x     Document Type: Review
Times cited : (63)

References (74)
  • 1
    • 33644543761 scopus 로고    scopus 로고
    • Expanding insights of mitochondrial dysfunction in Parkinson's disease
    • Abou-Sleiman P. M. Muqit M. M. Wood N. W. 2006 Expanding insights of mitochondrial dysfunction in Parkinson's disease. Nat. Rev. Neurosci. 7, 207 219.
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 207-219
    • Abou-Sleiman, P.M.1    Muqit, M.M.2    Wood, N.W.3
  • 2
    • 7244236320 scopus 로고    scopus 로고
    • Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
    • Arrasate M. Mitra S. Schweitzer E. S. Segal M. R. Finkbeiner S. 2004 Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. Nature 431, 805 810.
    • (2004) Nature , vol.431 , pp. 805-810
    • Arrasate, M.1    Mitra, S.2    Schweitzer, E.S.3    Segal, M.R.4    Finkbeiner, S.5
  • 4
    • 1542348209 scopus 로고    scopus 로고
    • The energetics of Huntington's disease
    • Browne S. E. Beal M. F. 2004 The energetics of Huntington's disease. Neurochem. Res. 29, 531 546.
    • (2004) Neurochem. Res. , vol.29 , pp. 531-546
    • Browne, S.E.1    Beal, M.F.2
  • 5
    • 0345099501 scopus 로고    scopus 로고
    • The polyglutamine neurodegenerative protein ataxin-3 binds polyubiquitinylated proteins and has ubiquitin protease activity
    • Burnett B. Li F. Pittman R. N. 2003 The polyglutamine neurodegenerative protein ataxin-3 binds polyubiquitinylated proteins and has ubiquitin protease activity. Hum. Mol. Genet. 12, 3195 3205.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 3195-3205
    • Burnett, B.1    Li, F.2    Pittman, R.N.3
  • 6
    • 0942287194 scopus 로고    scopus 로고
    • Poly-ubiquitin binding by the polyglutamine disease protein ataxin-3 links its normal function to protein surveillance pathways
    • Chai Y. Berke S. S. Cohen R. E. Paulson H. L. 2004 Poly-ubiquitin binding by the polyglutamine disease protein ataxin-3 links its normal function to protein surveillance pathways. J. Biol. Chem. 279, 3605 3611.
    • (2004) J. Biol. Chem. , vol.279 , pp. 3605-3611
    • Chai, Y.1    Berke, S.S.2    Cohen, R.E.3    Paulson, H.L.4
  • 7
    • 27944481282 scopus 로고    scopus 로고
    • How genetics research in Parkinson's disease is enhancing understanding of the common idiopathic forms of the disease
    • Cookson M. R. Xiromerisiou G. Singleton A. 2005 December How genetics research in Parkinson's disease is enhancing understanding of the common idiopathic forms of the disease. Curr. Opin. Neurol. 18, 706 711.
    • (2005) Curr. Opin. Neurol. , vol.18 , pp. 706-711
    • Cookson, M.R.1    Xiromerisiou, G.2    Singleton, A.3
  • 8
    • 0037177086 scopus 로고    scopus 로고
    • Cycad neurotoxins, consumption of flying foxes, and ALS-PDC disease in Guam
    • Cox P. A. Sacks O. W. 2002 Cycad neurotoxins, consumption of flying foxes, and ALS-PDC disease in Guam. Neurology 58, 956 959.
    • (2002) Neurology , vol.58 , pp. 956-959
    • Cox, P.A.1    Sacks, O.W.2
  • 9
    • 0034788220 scopus 로고    scopus 로고
    • Von Economo encephalitis
    • Dickman M. S. 2001 von Economo encephalitis. Arch. Neurol. 58, 1696 1698.
    • (2001) Arch. Neurol. , vol.58 , pp. 1696-1698
    • Dickman, M.S.1
  • 11
    • 4644372063 scopus 로고    scopus 로고
    • The tau H2 haplotype is almost exclusively Caucasian in origin
    • Evans W. et al. 2004 The tau H2 haplotype is almost exclusively Caucasian in origin. Neurosci. Lett. 369, 183 185.
    • (2004) Neurosci. Lett. , vol.369 , pp. 183-185
    • Evans, W.1
  • 12
    • 0034595722 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor in Huntington disease
    • Ferrer I. Goutan E. Marin C. Rey M. J. Ribalta T. 2000 Brain-derived neurotrophic factor in Huntington disease. Brain Res. 866, 257 261.
    • (2000) Brain Res. , vol.866 , pp. 257-261
    • Ferrer, I.1    Goutan, E.2    Marin, C.3    Rey, M.J.4    Ribalta, T.5
  • 13
    • 0030977392 scopus 로고    scopus 로고
    • Frontotemporal dementia and parkinsonism linked to chromosome 17: A consensus conference
    • Foster N. L. Wilhelmsen K. Sima A. A. Jones M. Z. D'Amato C. J. Gilman S. 1997 Frontotemporal dementia and parkinsonism linked to chromosome 17: a consensus conference. Ann. Neurol. 41, 706 715.
    • (1997) Ann. Neurol. , vol.41 , pp. 706-715
    • Foster, N.L.1    Wilhelmsen, K.2    Sima, A.A.3    Jones, M.Z.4    D'Amato, C.J.5    Gilman, S.6
  • 14
    • 25844487226 scopus 로고    scopus 로고
    • Diseases of unstable repeat expansion: Mechanism and common principles
    • Gatchel J. R. Zoghbi H. Y. 2005 Diseases of unstable repeat expansion: mechanism and common principles. Nat. Rev. Genet. 6, 743 755.
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 743-755
    • Gatchel, J.R.1    Zoghbi, H.Y.2
  • 15
    • 3142636768 scopus 로고    scopus 로고
    • Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules
    • Gauthier L. R. Charrin B. C. Borrell-pages M. et al. 2004 Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Cell 118, 127 138.
    • (2004) Cell , vol.118 , pp. 127-138
    • Gauthier, L.R.1    Charrin, B.C.2    Borrell-Pages, M.3
  • 16
    • 19944432921 scopus 로고    scopus 로고
    • A common LRRK2 mutation in idiopathic Parkinson's disease
    • Gilks W. P. Abou-Sleiman P. M. Gandhi S. et al. 2005 A common LRRK2 mutation in idiopathic Parkinson's disease. Lancet 365, 415 416.
    • (2005) Lancet , vol.365 , pp. 415-416
    • Gilks, W.P.1    Abou-Sleiman, P.M.2    Gandhi, S.3
  • 17
    • 33344463679 scopus 로고    scopus 로고
    • Common mechanisms of amyloid oligomer pathogenesis in degenerative disease
    • Glabe C. G. 2006 Common mechanisms of amyloid oligomer pathogenesis in degenerative disease. Neurobiol. Aging 27, 570 575.
    • (2006) Neurobiol. Aging , vol.27 , pp. 570-575
    • Glabe, C.G.1
  • 18
    • 13544272023 scopus 로고    scopus 로고
    • The Abeta hypothesis. leading us to rationally-designed therapeutic strategies for the treatment or prevention of Alzheimer disease
    • Golde T. E. 2005 The Abeta hypothesis. leading us to rationally-designed therapeutic strategies for the treatment or prevention of Alzheimer disease. Brain Pathol. 15, 84 87.
    • (2005) Brain Pathol. , vol.15 , pp. 84-87
    • Golde, T.E.1
  • 19
    • 12144280807 scopus 로고    scopus 로고
    • Polyglutamine diseases and transport problems: Deadly traffic jams on neuronal highways
    • Gunawardena S. Goldstein L. S. 2005 Polyglutamine diseases and transport problems: deadly traffic jams on neuronal highways. Arch. Neurol. 62, 46 51.
    • (2005) Arch. Neurol. , vol.62 , pp. 46-51
    • Gunawardena, S.1    Goldstein, L.S.2
  • 20
    • 26444607034 scopus 로고    scopus 로고
    • Parkinson's disease: A broken nosology
    • Hardy J. Lees A. J. 2005 Parkinson's disease: a broken nosology. Mov. Disord. 20, S2 S4.
    • (2005) Mov. Disord. , vol.20
    • Hardy, J.1    Lees, A.J.2
  • 21
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • Hardy J. Selkoe D. J. 2002 The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297, 353 356.
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 22
    • 0032150877 scopus 로고    scopus 로고
    • Genetic dissection of Alzheimer's disease and related dementias. amyloid and its relationship to tau
    • Hardy J. Duff K. Gwinn-Hardy K. Pérez-Tur J. Hutton M. 1998 Genetic dissection of Alzheimer's disease and related dementias. amyloid and its relationship to tau. Nat. Neurosci. 1, 355 358.
    • (1998) Nat. Neurosci. , vol.1 , pp. 355-358
    • Hardy, J.1    Duff, K.2    Gwinn-Hardy, K.3    Pérez-Tur, J.4    Hutton, M.5
  • 23
    • 33645059953 scopus 로고    scopus 로고
    • Frontal temporal dementia: Dissecting the aetiology and pathogenesis
    • Hardy J. Momeni P. Traynor B. J. 2006 Frontal temporal dementia: dissecting the aetiology and pathogenesis. Brain 129, 830 831.
    • (2006) Brain , vol.129 , pp. 830-831
    • Hardy, J.1    Momeni, P.2    Traynor, B.J.3
  • 24
    • 0038389601 scopus 로고    scopus 로고
    • Transgenic models of alpha-synuclein pathology: Past, present, and future
    • Hashimoto M. Rockenstein E. Masliah E. 2003 Transgenic models of alpha-synuclein pathology: past, present, and future. Ann. NY Acad. Sci. 991, 171 188.
    • (2003) Ann. NY Acad. Sci. , vol.991 , pp. 171-188
    • Hashimoto, M.1    Rockenstein, E.2    Masliah, E.3
  • 25
    • 0035940582 scopus 로고    scopus 로고
    • Improved accuracy of clinical diagnosis of Lewy body Parkinson's disease
    • Hughes A. J. Daniel S. E. Lees A. J. 2001 Improved accuracy of clinical diagnosis of Lewy body Parkinson's disease. Neurology 57, 1497 1499.
    • (2001) Neurology , vol.57 , pp. 1497-1499
    • Hughes, A.J.1    Daniel, S.E.2    Lees, A.J.3
  • 26
    • 0034971707 scopus 로고    scopus 로고
    • Missense and splice site mutations in tau associated with FTDP-17: Multiple pathogenic mechanisms
    • Hutton M. 2001 Missense and splice site mutations in tau associated with FTDP-17: multiple pathogenic mechanisms. Neurology 56, S21 S25.
    • (2001) Neurology , vol.56
    • Hutton, M.1
  • 28
    • 0036892302 scopus 로고    scopus 로고
    • Tau gene mutations: Dissecting the pathogenesis of FTDP-17
    • Ingram E. M. Spillantini M. G. 2002 Tau gene mutations: dissecting the pathogenesis of FTDP-17. Trends Mol. Med. 8, 555 562.
    • (2002) Trends Mol. Med. , vol.8 , pp. 555-562
    • Ingram, E.M.1    Spillantini, M.G.2
  • 29
    • 18644379256 scopus 로고    scopus 로고
    • Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy
    • Katsuno M. Adachi H. Kume A. Li M. Nakagomi Y. Niwa H. Sang C. Kobayashi Y. Doyu M. Sobue G. 2002 Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy. Neuron 35, 843 854.
    • (2002) Neuron , vol.35 , pp. 843-854
    • Katsuno, M.1    Adachi, H.2    Kume, A.3    Li, M.4    Nakagomi, Y.5    Niwa, H.6    Sang, C.7    Kobayashi, Y.8    Doyu, M.9    Sobue, G.10
  • 30
    • 0038714285 scopus 로고    scopus 로고
    • Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy
    • Katsuno M. Adachi H. Doyu M. Minamiyama M. Sang C. Kobayashi Y. Inukai A. Sobue G. 2003 Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy. Nat. Med. 9, 768 773.
    • (2003) Nat. Med. , vol.9 , pp. 768-773
    • Katsuno, M.1    Adachi, H.2    Doyu, M.3    Minamiyama, M.4    Sang, C.5    Kobayashi, Y.6    Inukai, A.7    Sobue, G.8
  • 31
    • 2542455537 scopus 로고    scopus 로고
    • Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease
    • Klein W. L. Stine W. B. Jr. Teplow D. B. 2004 Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease. Neurobiol. Aging. 25, 569 580.
    • (2004) Neurobiol. Aging. , vol.25 , pp. 569-580
    • Klein, W.L.1    Stine Jr., W.B.2    Teplow, D.B.3
  • 32
    • 0032475941 scopus 로고    scopus 로고
    • Ataxin-1 nuclear localization and aggregation: Role in polyglutamine-induced disease in SCA1 transgenic mice
    • Klement I. A. Skinner P. J. Kaytor M. D. Yi H. Hersch S. M. Clark H. B. Zoghbi H. Y. Orr H. T. 1998 Ataxin-1 nuclear localization and aggregation: Role in polyglutamine-induced disease in SCA1 transgenic mice. Cell 95, 41 53.
    • (1998) Cell , vol.95 , pp. 41-53
    • Klement, I.A.1    Skinner, P.J.2    Kaytor, M.D.3    Yi, H.4    Hersch, S.M.5    Clark, H.B.6    Zoghbi, H.Y.7    Orr, H.T.8
  • 33
    • 14744283221 scopus 로고
    • Parkinsonism-dementia complex, en endemic disease on the island of Guam. Clinical, pathological, genetic and epidemiological features
    • Kurland L. T. Hirano A. Malaud N. Lessell S. 1961 Parkinsonism-dementia complex, en endemic disease on the island of Guam. Clinical, pathological, genetic and epidemiological features. Trans. Am. Neurol. Assoc. 86, 115 120.
    • (1961) Trans. Am. Neurol. Assoc. , vol.86 , pp. 115-120
    • Kurland, L.T.1    Hirano, A.2    Malaud, N.3    Lessell, S.4
  • 34
    • 0025800526 scopus 로고
    • Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy
    • La Spada A. R. Wilson E. M. Lubahn D. B. Harding A. E. Fischbeck K. H. 1991 Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy. Nature 352, 77 79.
    • (1991) Nature , vol.352 , pp. 77-79
    • La Spada, A.R.1    Wilson, E.M.2    Lubahn, D.B.3    Harding, A.E.4    Fischbeck, K.H.5
  • 35
    • 17044439021 scopus 로고    scopus 로고
    • Alzheimer's disease: Abeta, tau and synaptic dysfunction
    • LaFerla F. M. Oddo S. 2005 April Alzheimer's disease: Abeta, tau and synaptic dysfunction. Trends Mol. Med. 11, 170 176.
    • (2005) Trends Mol. Med. , vol.11 , pp. 170-176
    • Laferla, F.M.1    Oddo, S.2
  • 36
    • 20444479483 scopus 로고    scopus 로고
    • Amyloid-beta in Alzheimer's disease: The horse or the cart? Pathogenic or protective?
    • Lee H. G. Castellani R. J. Zhu X. Perry G. Smith M. A. 2005 June Amyloid-beta in Alzheimer's disease: the horse or the cart? Pathogenic or protective? Int. J. Exp. Pathol. 86, 133 138.
    • (2005) Int. J. Exp. Pathol. , vol.86 , pp. 133-138
    • Lee, H.G.1    Castellani, R.J.2    Zhu, X.3    Perry, G.4    Smith, M.A.5
  • 38
    • 1342321775 scopus 로고    scopus 로고
    • More than just two peas in a pod: Common amyloidogenic properties of tau and alpha-synuclein in neurodegenerative diseases
    • Lee V. M. Giasson B. I. Trojanowski J. Q. 2004 More than just two peas in a pod: common amyloidogenic properties of tau and alpha-synuclein in neurodegenerative diseases. Trends Neurosci. 27, 129 134.
    • (2004) Trends Neurosci. , vol.27 , pp. 129-134
    • Lee, V.M.1    Giasson, B.I.2    Trojanowski, J.Q.3
  • 41
    • 23844441835 scopus 로고    scopus 로고
    • Ubiquitin immunohistochemistry suggests classic motor neuron disease, motor neuron disease with dementia, and frontotemporal dementia of the motor neuron disease type represent a clinicopathologic spectrum
    • Mackenzie I. R. Feldman H. H. 2005 Ubiquitin immunohistochemistry suggests classic motor neuron disease, motor neuron disease with dementia, and frontotemporal dementia of the motor neuron disease type represent a clinicopathologic spectrum. J. Neuropathol. Exp. Neurol. 64, 730 739.
    • (2005) J. Neuropathol. Exp. Neurol. , vol.64 , pp. 730-739
    • MacKenzie, I.R.1    Feldman, H.H.2
  • 42
    • 33645072728 scopus 로고    scopus 로고
    • A family with tau-negative frontotemporal dementia and neuronal intranuclear inclusions linked to chromosome 17
    • Mackenzie I. R. Baker M. West G. et al. 2006 A family with tau-negative frontotemporal dementia and neuronal intranuclear inclusions linked to chromosome 17. Brain 129, 853 867.
    • (2006) Brain , vol.129 , pp. 853-867
    • MacKenzie, I.R.1    Baker, M.2    West, G.3
  • 43
    • 16044373842 scopus 로고    scopus 로고
    • Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
    • Mangiarini L. et al. 1996 Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell. 87, 493 506.
    • (1996) Cell. , vol.87 , pp. 493-506
    • Mangiarini, L.1
  • 44
    • 20444413356 scopus 로고    scopus 로고
    • Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease
    • Masliah E. Rockenstein E. Adame A. et al. 2005 Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease. Neuron 46, 857 868.
    • (2005) Neuron , vol.46 , pp. 857-868
    • Masliah, E.1    Rockenstein, E.2    Adame, A.3
  • 45
    • 33645062075 scopus 로고    scopus 로고
    • A locus on chromosome 9p confers susceptibility to ALS and frontotemporal dementia
    • Morita M. Al-Chalabi A. Andersen P. M. et al. 2006 A locus on chromosome 9p confers susceptibility to ALS and frontotemporal dementia. Neurology 28, 839 844.
    • (2006) Neurology , vol.28 , pp. 839-844
    • Morita, M.1    Al-Chalabi, A.2    Andersen, P.M.3
  • 46
    • 10044236749 scopus 로고    scopus 로고
    • Genome-wide analysis of the parkinsonism-dementia complex of Guam
    • Morris H. R. Steele J. C. Crook R. et al. 2004 Genome-wide analysis of the parkinsonism-dementia complex of Guam. Arch. Neurol. 61, 1889 1897.
    • (2004) Arch. Neurol. , vol.61 , pp. 1889-1897
    • Morris, H.R.1    Steele, J.C.2    Crook, R.3
  • 48
    • 21044449225 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo
    • Noble W. Planel E. Zehr C. et al. 2005 May 10 Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo. Proc. Natl Acad. Sci. USA 102, 6990 6995.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 6990-6995
    • Noble, W.1    Planel, E.2    Zehr, C.3
  • 49
    • 0034756931 scopus 로고    scopus 로고
    • TAU as a susceptibility gene for amyotropic lateral sclerosis- parkinsonism dementia complex of Guam
    • Poorkaj P. Tsuang D. Wijsman E. et al. 2001 TAU as a susceptibility gene for amyotropic lateral sclerosis-parkinsonism dementia complex of Guam. Arch. Neurol. 58, 1871 1878.
    • (2001) Arch. Neurol. , vol.58 , pp. 1871-1878
    • Poorkaj, P.1    Tsuang, D.2    Wijsman, E.3
  • 51
    • 0036364359 scopus 로고    scopus 로고
    • The solved and unsolved mysteries of the genetics of early-onset alzheimer's disease
    • Rogaeva E. 2002 The solved and unsolved mysteries of the genetics of early-onset alzheimer's disease. Neuromolecular Med. 2, 1 10.
    • (2002) Neuromolecular Med. , vol.2 , pp. 1-10
    • Rogaeva, E.1
  • 52
    • 29444442794 scopus 로고    scopus 로고
    • APP locus duplication causes autosomal dominant early-onset alzheimer disease with cerebral amyloid angiopathy
    • Rovelet-Lecrux A. Hannequin D. Raux G. et al. 2006 APP locus duplication causes autosomal dominant early-onset alzheimer disease with cerebral amyloid angiopathy. Nat. Genet. 38, 24 26.
    • (2006) Nat. Genet. , vol.38 , pp. 24-26
    • Rovelet-Lecrux, A.1    Hannequin, D.2    Raux, G.3
  • 53
    • 4444362840 scopus 로고    scopus 로고
    • Current progress in beta-amyloid immunotherapy
    • Schenk D. Hagen M. Seubert P. 2004 Current progress in beta-amyloid immunotherapy. Curr. Opin. Immunol. 16, 599 606.
    • (2004) Curr. Opin. Immunol. , vol.16 , pp. 599-606
    • Schenk, D.1    Hagen, M.2    Seubert, P.3
  • 54
    • 0037056302 scopus 로고    scopus 로고
    • Expression of X-linked bulbospin al muscular atrophy (kennedy's disease) in two homozygous women
    • Schmidt B. J. Greenberg C. R. Allingham-Hawkins D. J. Sproggsm E. L. 2002 Expression of X-linked bulbospin al muscular atrophy (kennedy's disease) in two homozygous women. Neurology 59, 770 772.
    • (2002) Neurology , vol.59 , pp. 770-772
    • Schmidt, B.J.1    Greenberg, C.R.2    Allingham-Hawkins, D.J.3    Sproggsm, E.L.4
  • 56
    • 26444441008 scopus 로고    scopus 로고
    • HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism
    • Seong I. S. Ivanova E. Lee J.-M. et al. 2005 HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism. Hum. Mol. Genet. 14, 2871 2880.
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 2871-2880
    • Seong, I.S.1    Ivanova, E.2    Lee, J.-M.3
  • 57
    • 10944223484 scopus 로고    scopus 로고
    • Tau protein as a differential biomarker of tauopathies
    • Sergeant N. Delacourte A. Buee L. 2005 Tau protein as a differential biomarker of tauopathies. Biochim. Biophys. Acta 1739, 179 197.
    • (2005) Biochim. Biophys. Acta , vol.1739 , pp. 179-197
    • Sergeant, N.1    Delacourte, A.2    Buee, L.3
  • 58
    • 22144439077 scopus 로고    scopus 로고
    • Altered alpha-synuclein homeostasis causing Parkinson's disease: The potential roles of dardarin
    • Singleton A. B. 2005 Altered alpha-synuclein homeostasis causing Parkinson's disease: the potential roles of dardarin. Trends Neurosci. 28, 416 421.
    • (2005) Trends Neurosci. , vol.28 , pp. 416-421
    • Singleton, A.B.1
  • 59
    • 1842507639 scopus 로고    scopus 로고
    • The law of mass action applied to neurodegenerative disease: A hypothesis concerning the etiology and pathogenesis of complex diseases
    • Singleton A. Myers A. Hardy J. 2004 The law of mass action applied to neurodegenerative disease: a hypothesis concerning the etiology and pathogenesis of complex diseases. Hum. Mol. Genet. 13 Spec. 1, R123 R126.
    • (2004) Hum. Mol. Genet. , vol.13 , Issue.SPEC. 1
    • Singleton, A.1    Myers, A.2    Hardy, J.3
  • 61
    • 13944278863 scopus 로고    scopus 로고
    • A common inversion under selection in Europeans
    • Stefansson H. et al. 2005 A common inversion under selection in Europeans. Nat. Genet. 37, 129 137.
    • (2005) Nat. Genet. , vol.37 , pp. 129-137
    • Stefansson, H.1
  • 62
    • 0037408279 scopus 로고    scopus 로고
    • Transcriptional abnormalities in Huntington disease
    • Sugars K. L. Rubinsztein D. C. 2003 Transcriptional abnormalities in Huntington disease. Trends Genet. 19, 233 238.
    • (2003) Trends Genet. , vol.19 , pp. 233-238
    • Sugars, K.L.1    Rubinsztein, D.C.2
  • 64
    • 0242361780 scopus 로고    scopus 로고
    • Role of proteolysis in polyglutamine disorders
    • Tarlac V. Storey E. 2003 Role of proteolysis in polyglutamine disorders. J. Neurosci. Res. 74, 406 416.
    • (2003) J. Neurosci. Res. , vol.74 , pp. 406-416
    • Tarlac, V.1    Storey, E.2
  • 65
    • 33645089933 scopus 로고    scopus 로고
    • A Belgian ancestral haplotype harbours a highly prevalent mutation for 17q21-linked tau-negative FTLD
    • van der Zee J. et al. 2006 A Belgian ancestral haplotype harbours a highly prevalent mutation for 17q21-linked tau-negative FTLD. Brain 129, 841 852.
    • (2006) Brain , vol.129 , pp. 841-852
    • Van Der Zee, J.1
  • 66
    • 33645069660 scopus 로고    scopus 로고
    • Familial amyotrophic lateral sclerosis with frontotemporal dementia is linked to a locus on chromosome 9p13.2-21.3
    • Vance C. et al. 2006 Familial amyotrophic lateral sclerosis with frontotemporal dementia is linked to a locus on chromosome 9p13.2-21.3. Brain 129, 868 876.
    • (2006) Brain , vol.129 , pp. 868-876
    • Vance, C.1
  • 69
    • 1842483843 scopus 로고    scopus 로고
    • Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein
    • Watts G. D. J. Wymer J. Kovach M. J. Mehta S. G. Mumm S. Darvish D. Pestronk A. Whyte M. P. Kimonis V. E. 2004 Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein. Nat. Genet. 36, 377 381.
    • (2004) Nat. Genet. , vol.36 , pp. 377-381
    • Watts, G.D.J.1    Wymer, J.2    Kovach, M.J.3    Mehta, S.G.4    Mumm, S.5    Darvish, D.6    Pestronk, A.7    Whyte, M.P.8    Kimonis, V.E.9
  • 71
    • 5344240284 scopus 로고    scopus 로고
    • Amyloid-beta precursor protein processing in neurodegeneration
    • Wilquet V. De Strooper B. 2004 Amyloid-beta precursor protein processing in neurodegeneration. Curr. Opin. Neurobiol. 14, 582 588.
    • (2004) Curr. Opin. Neurobiol. , vol.14 , pp. 582-588
    • Wilquet, V.1    De Strooper, B.2
  • 72
    • 8844233579 scopus 로고    scopus 로고
    • Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology
    • Zimprich A. Biskup S. Leitner P. et al. 2004 Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron 44, 601 607.
    • (2004) Neuron , vol.44 , pp. 601-607
    • Zimprich, A.1    Biskup, S.2    Leitner, P.3
  • 73
    • 0034094873 scopus 로고    scopus 로고
    • Glutamine repeats and neurodegeneration
    • Zoghbi H. Y. Orr H. T. 2000 Glutamine repeats and neurodegeneration. Annu. Rev. Neurosci. 23, 217 247.
    • (2000) Annu. Rev. Neurosci. , vol.23 , pp. 217-247
    • Zoghbi, H.Y.1    Orr, H.T.2
  • 74
    • 0035919701 scopus 로고    scopus 로고
    • Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease
    • Zuccato C. Ciammola A. Rigamonti D. et al. 2001 Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease. Science 293, 493 498.
    • (2001) Science , vol.293 , pp. 493-498
    • Zuccato, C.1    Ciammola, A.2    Rigamonti, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.