메뉴 건너뛰기




Volumn 127, Issue 4, 2005, Pages 1312-1326

Cysteinyl leukotrienes in allergic inflammation: Strategic target for therapy

Author keywords

Asthma; Cytokines; Eosinophils; Inflammation; Leukotriene receptor antagonists; Leukotrienes; Remodeling; Rhinitis

Indexed keywords

ACETYLSALICYLIC ACID; BECLOMETASONE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BUDESONIDE; CORTICOSTEROID; LEUKOTRIENE RECEPTOR; METHACHOLINE; MONTELUKAST; NITRIC OXIDE; PEPTIDOLEUKOTRIENE; PRANLUKAST; ZAFIRLUKAST; AUTACOID; CYSTEINE; CYSTEINYL-LEUKOTRIENE; LEUKOTRIENE;

EID: 19044376965     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.127.4.1312     Document Type: Review
Times cited : (136)

References (116)
  • 2
    • 0001611594 scopus 로고    scopus 로고
    • Expert panel report: Guidelines for the diagnosis and management of asthma update on selected topics-2002
    • National Asthma Education and Prevention Program
    • National Asthma Education and Prevention Program. Expert panel report: guidelines for the diagnosis and management of asthma update on selected topics-2002. J Allergy Clin Immunol 2002; 110:5141-5219
    • (2002) J Allergy Clin Immunol , vol.110 , pp. 5141-5219
  • 3
    • 0004002716 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and management of asthma: Expert panel
    • National Asthma Education and Prevention Program
    • National Asthma Education and Prevention Program. Guidelines for the diagnosis and management of asthma: expert panel report 2. Bethesda, MD: National Institutes of Health/National Heart, Lung, and Blood Institute, 1997
    • (1997) Bethesda, MD: National Institutes of Health/National Heart, Lung, and Blood Institute
  • 4
    • 0003545924 scopus 로고
    • Allergy of the upper respiratory tract
    • Lawlor GJ, Fischer TJ, Adelman DC, eds, Boston, MA: Little, Brown and Company
    • Lierl MB. Allergy of the upper respiratory tract. In: Lawlor GJ, Fischer TJ, Adelman DC, eds. Manual of allergy and immunology. Boston, MA: Little, Brown and Company, 1995; 95-111
    • (1995) Manual of allergy and immunology , pp. 95-111
    • Lierl, M.B.1
  • 7
    • 0031744525 scopus 로고    scopus 로고
    • Leukotrienes and inflammation
    • discussion 5247-5218
    • Busse WW. Leukotrienes and inflammation. Am J Respir Crit Care Med 1998; 157:5210-5213; discussion 5247-5218
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 5210-5213
    • Busse, W.W.1
  • 8
    • 0020642778 scopus 로고
    • 4: Comparison of potency in canine trachea in vivo
    • 4: comparison of potency in canine trachea in vivo. Prostaglandins 1983; 25:237-243
    • (1983) Prostaglandins , vol.25 , pp. 237-243
    • Johnson, H.G.1    McNee, M.L.2
  • 9
    • 0037251708 scopus 로고    scopus 로고
    • Inflammatory cells in asthma: Mechanisms and implications for therapy
    • discussion S12-S17
    • Hamid Q, Tulic MK, Liu MC, et al. Inflammatory cells in asthma: mechanisms and implications for therapy. J Allergy Clin Immunol 2003; 111:55-512; discussion S12-S17
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 55-512
    • Hamid, Q.1    Tulic, M.K.2    Liu, M.C.3
  • 10
    • 0034929204 scopus 로고    scopus 로고
    • The anti-inflammatory effects of leukotriene-modifying drugs and their use in asthma
    • Salvi SS, Krishna MT, Sampson AP, et al. The anti-inflammatory effects of leukotriene-modifying drugs and their use in asthma. Chest 2001; 119:1533-1546
    • (2001) Chest , vol.119 , pp. 1533-1546
    • Salvi, S.S.1    Krishna, M.T.2    Sampson, A.P.3
  • 11
    • 85004775161 scopus 로고
    • 4 on nasal mucosal blood flow, nasal airway resistance and nasal secretion in humans
    • 4 on nasal mucosal blood flow, nasal airway resistance and nasal secretion in humans. Clin Allergy 1986; 16:289-297
    • (1986) Clin Allergy , vol.16 , pp. 289-297
    • Bisgaard, H.1    Olsson, P.2    Bende, M.3
  • 12
    • 0029152856 scopus 로고
    • Cysteinyl leukotrienes in asthma: Old mediators up to new tricks
    • Hay DW, Torphy TJ, Undem BJ. Cysteinyl leukotrienes in asthma: old mediators up to new tricks. Trends Pharmacol Sci 1995; 16:304-309
    • (1995) Trends Pharmacol Sci , vol.16 , pp. 304-309
    • Hay, D.W.1    Torphy, T.J.2    Undem, B.J.3
  • 13
    • 0020597565 scopus 로고
    • Leukotrienes: Mediators of immediate hypersensitivity reactions and inflammation
    • Samuelsson B. Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. Science 1983; 220: 568-575
    • (1983) Science , vol.220 , pp. 568-575
    • Samuelsson, B.1
  • 14
    • 0034047709 scopus 로고    scopus 로고
    • Leukotriene receptor antagonists and synthesis inhibitors reverse survival in eosinophils of asthmatic individuals
    • Lee E, Robertson T, Smith J, et al. Leukotriene receptor antagonists and synthesis inhibitors reverse survival in eosinophils of asthmatic individuals. Am J Respir Crit Care Med 2000; 161:1881-1886
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 1881-1886
    • Lee, E.1    Robertson, T.2    Smith, J.3
  • 15
    • 0024477342 scopus 로고
    • 4 after antigen challenge and in acute asthma and allergic rhinitis
    • 4 after antigen challenge and in acute asthma and allergic rhinitis. Lancet 1989; 1:584-588
    • (1989) Lancet , vol.1 , pp. 584-588
    • Taylor, G.W.1    Taylor, I.2    Black, P.3
  • 17
    • 0030696614 scopus 로고    scopus 로고
    • 4 after exercise and attenuation of exercise-induced ronchospasm by montelukast, a cysteinyl leukotriene receptor antagonist
    • 4 after exercise and attenuation of exercise-induced ronchospasm by montelukast, a cysteinyl leukotriene receptor antagonist. Thorax 1997; 52:1030-1035
    • (1997) Thorax , vol.52 , pp. 1030-1035
    • Reiss, T.F.1    Hill, J.B.2    Harman, E.3
  • 18
    • 0025284206 scopus 로고
    • 4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challenge
    • 4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challenge. Am Rev Respir Dis 1990; 142:112-119
    • (1990) Am Rev Respir Dis , vol.142 , pp. 112-119
    • Wenzel, S.E.1    Larsen, G.L.2    Johnston, K.3
  • 19
    • 0033456233 scopus 로고    scopus 로고
    • Induced sputum eicosanoid concentrations in asthma
    • Pavord ID, Ward R, Woltmann G, et al. Induced sputum eicosanoid concentrations in asthma. Am J Respir Crit Care Med 1999; 160:1905-1909
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 1905-1909
    • Pavord, I.D.1    Ward, R.2    Woltmann, G.3
  • 20
    • 0034027995 scopus 로고    scopus 로고
    • Sputum cysteinyl leukotrienes increase 24 hours after allergen inhalation in atopic asthmatics
    • Macfarlane AJ, Dworski R, Sheller JR, et al. Sputum cysteinyl leukotrienes increase 24 hours after allergen inhalation in atopic asthmatics. Am J Respir Crit Care Med 2000; 161:1553-1558
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 1553-1558
    • Macfarlane, A.J.1    Dworski, R.2    Sheller, J.R.3
  • 23
    • 0034889431 scopus 로고    scopus 로고
    • Cloning and expression of leukotriene receptors
    • Evans J, Figueroa DJ. Cloning and expression of leukotriene receptors. Clin Exp Allergy Rev 2001; 1:142-144
    • (2001) Clin Exp Allergy Rev , vol.1 , pp. 142-144
    • Evans, J.1    Figueroa, D.J.2
  • 24
    • 0035152877 scopus 로고    scopus 로고
    • Expression of the cysteinyl leukotriene 1 receptor in normal human lung and peripheral blood leukocytes
    • Figueroa DJ, Breyer RM, Defoe SK, et al. Expression of the cysteinyl leukotriene 1 receptor in normal human lung and peripheral blood leukocytes. Am J Respir Crit Care Med 2001; 163:226-233
    • (2001) Am J Respir Crit Care Med , vol.163 , pp. 226-233
    • Figueroa, D.J.1    Breyer, R.M.2    Defoe, S.K.3
  • 25
    • 0034933024 scopus 로고    scopus 로고
    • Cysteinyl leukotriene receptor 1 is also a pyrimidinergic receptor and is expressed by human mast cells
    • Mellor EA, Maekawa A, Austen KF, et al. Cysteinyl leukotriene receptor 1 is also a pyrimidinergic receptor and is expressed by human mast cells. Proc Natl Acad Sci USA 2001; 98:7964-7969
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 7964-7969
    • Mellor, E.A.1    Maekawa, A.2    Austen, K.F.3
  • 26
    • 0035987304 scopus 로고    scopus 로고
    • Expression and localization of the cysteinyl leukotriene 1 receptor in human nasal mucosa
    • Shirasaki H, Kanaizumi E, Watanabe K, et al. Expression and localization of the cysteinyl leukotriene 1 receptor in human nasal mucosa. Clin Exp Allergy 2002; 32:1007-1012
    • (2002) Clin Exp Allergy , vol.32 , pp. 1007-1012
    • Shirasaki, H.1    Kanaizumi, E.2    Watanabe, K.3
  • 27
    • 0034947079 scopus 로고    scopus 로고
    • Analysis of montelukast in mild persistent asthmatic patients with near-normal lung function
    • Barnes N, Wei LX, Reiss TF, et al. Analysis of montelukast in mild persistent asthmatic patients with near-normal lung function. Respir Med 2001; 95:379-386
    • (2001) Respir Med , vol.95 , pp. 379-386
    • Barnes, N.1    Wei, L.X.2    Reiss, T.F.3
  • 28
    • 0030875339 scopus 로고    scopus 로고
    • Zafirlukast for symptomatic mild-to-moderate asthma: A 13-week multicenter study. The Zafirlukast Trialists Group
    • Fish JE, Kemp JP, Lockey RF, et al. Zafirlukast for symptomatic mild-to-moderate asthma: a 13-week multicenter study. The Zafirlukast Trialists Group. Clin Ther 1997; 19:675-690
    • (1997) Clin Ther , vol.19 , pp. 675-690
    • Fish, J.E.1    Kemp, J.P.2    Lockey, R.F.3
  • 29
    • 0032496618 scopus 로고    scopus 로고
    • Montelukast, a once-daily leukotriene receptor antagonist, in the treatment of chronic asthma: A multicenter, randomized, double-blind trial. Montelukast Clinical Research Study Group
    • Reiss TF, Chervinsky P, Dockhorn RJ, et al. Montelukast, a once-daily leukotriene receptor antagonist, in the treatment of chronic asthma: a multicenter, randomized, double-blind trial. Montelukast Clinical Research Study Group. Arch Intern Med 1998; 158:1213-1220
    • (1998) Arch Intern Med , vol.158 , pp. 1213-1220
    • Reiss, T.F.1    Chervinsky, P.2    Dockhorn, R.J.3
  • 30
    • 0030872408 scopus 로고    scopus 로고
    • Barnes NC, Pujet JC. Pranlukast, a novel leukotriene receptor antagonist: results of the first European, placebo controlled, multicentre clinical study in asthma. Thorax 1997; 52:523-527
    • Barnes NC, Pujet JC. Pranlukast, a novel leukotriene receptor antagonist: results of the first European, placebo controlled, multicentre clinical study in asthma. Thorax 1997; 52:523-527
  • 31
    • 0032962751 scopus 로고    scopus 로고
    • Therapeutic effect of zafirlukast as monotherapy in steroid-naive patients with severe persistent asthma
    • Kemp JP, Minkwitz MC, Bonuccelli CM, et al. Therapeutic effect of zafirlukast as monotherapy in steroid-naive patients with severe persistent asthma. Chest 1999; 115:336-342
    • (1999) Chest , vol.115 , pp. 336-342
    • Kemp, J.P.1    Minkwitz, M.C.2    Bonuccelli, C.M.3
  • 32
    • 0034057041 scopus 로고    scopus 로고
    • Comparison of the effects of intravenous and oral montelukast on airway function: A double blind, placebo controlled, three period, crossover study in asthmatic patients
    • Dockhorn RJ, Baumgartner RA, Leff JA, et al. Comparison of the effects of intravenous and oral montelukast on airway function: a double blind, placebo controlled, three period, crossover study in asthmatic patients. Thorax 2000; 55:260-265
    • (2000) Thorax , vol.55 , pp. 260-265
    • Dockhorn, R.J.1    Baumgartner, R.A.2    Leff, J.A.3
  • 33
    • 0036256066 scopus 로고    scopus 로고
    • Effect of montelukast, a once-daily leukotriene receptor antagonist, on peak expiratory flow variability
    • Zhang J, Yu C, Noonan G, et al. Effect of montelukast, a once-daily leukotriene receptor antagonist, on peak expiratory flow variability. Clin Ther 2002; 24:574-582
    • (2002) Clin Ther , vol.24 , pp. 574-582
    • Zhang, J.1    Yu, C.2    Noonan, G.3
  • 34
    • 0033928111 scopus 로고    scopus 로고
    • Effects of pranlukast, a cysteinyl leukotriene antagonist, on bronchial responsiveness to methacholine in aspirin-intolerant asthmatics treated with corticosteroids
    • Ishioka S, Hozawa S, Haruta Y, et al. Effects of pranlukast, a cysteinyl leukotriene antagonist, on bronchial responsiveness to methacholine in aspirin-intolerant asthmatics treated with corticosteroids. Hiroshima J Med Sci 2000; 49:105-108
    • (2000) Hiroshima J Med Sci , vol.49 , pp. 105-108
    • Ishioka, S.1    Hozawa, S.2    Haruta, Y.3
  • 35
    • 0034918651 scopus 로고    scopus 로고
    • Efficacy and safety of long-term treatment of asthmatic patients with pranlukast, a cysteinyl-leukotriene- receptor antagonist: Four-year follow-up study
    • Obase Y, Shimoda T, Tomari S, et al. Efficacy and safety of long-term treatment of asthmatic patients with pranlukast, a cysteinyl-leukotriene- receptor antagonist: four-year follow-up study. Ann Allergy Asthma Immunol 2001; 87:43-47
    • (2001) Ann Allergy Asthma Immunol , vol.87 , pp. 43-47
    • Obase, Y.1    Shimoda, T.2    Tomari, S.3
  • 36
    • 0035487252 scopus 로고    scopus 로고
    • Leukotriene receptor antagonists (montelukast) in the treatment of asthma crisis: Preliminary results of a double-blind placebo controlled randomized study
    • Ferreira MB, Santos AS, Pregal AL, et al. Leukotriene receptor antagonists (montelukast) in the treatment of asthma crisis: preliminary results of a double-blind placebo controlled randomized study. Allerg Immunol (Paris) 2001; 33:315-318
    • (2001) Allerg Immunol (Paris) , vol.33 , pp. 315-318
    • Ferreira, M.B.1    Santos, A.S.2    Pregal, A.L.3
  • 37
    • 0033574195 scopus 로고    scopus 로고
    • Oral montelukast, inhaled beclomethasone, and placebo for chronic asthma: A randomized, controlled trial. Montelukast/Beclomethasone Study Group
    • Malmstrom K, Rodriguez-Gomez G, Guerra J, et al. Oral montelukast, inhaled beclomethasone, and placebo for chronic asthma: a randomized, controlled trial. Montelukast/Beclomethasone Study Group. Ann Intern Med 1999; 130: 487-495
    • (1999) Ann Intern Med , vol.130 , pp. 487-495
    • Malmstrom, K.1    Rodriguez-Gomez, G.2    Guerra, J.3
  • 38
    • 0036907604 scopus 로고    scopus 로고
    • Effects of montelukast and beclomethasone on airway function and asthma control
    • Israel E, Chervinsky PS, Friedman B, et al. Effects of montelukast and beclomethasone on airway function and asthma control. J Allergy Clin Immunol 2002; 110:847-854
    • (2002) J Allergy Clin Immunol , vol.110 , pp. 847-854
    • Israel, E.1    Chervinsky, P.S.2    Friedman, B.3
  • 39
    • 12244310795 scopus 로고    scopus 로고
    • Distribution of therapeutic response in asthma control between oral montelukast and inhaled beclomethasone
    • Baumgartner RA, Martinez G, Edelman JM, et al. Distribution of therapeutic response in asthma control between oral montelukast and inhaled beclomethasone. Eur Respir J 2003; 21:123-128
    • (2003) Eur Respir J , vol.21 , pp. 123-128
    • Baumgartner, R.A.1    Martinez, G.2    Edelman, J.M.3
  • 40
    • 0035726032 scopus 로고    scopus 로고
    • Long-term asthma control with oral montelukast and inhaled beclomethasone for adults and children 6 years and older
    • Williams B, Noonan G, Reiss TF, et al. Long-term asthma control with oral montelukast and inhaled beclomethasone for adults and children 6 years and older. Clin Exp Allergy 2001; 31:845-854
    • (2001) Clin Exp Allergy , vol.31 , pp. 845-854
    • Williams, B.1    Noonan, G.2    Reiss, T.F.3
  • 41
    • 0037350379 scopus 로고    scopus 로고
    • Comparison of montelukast and budesonide on bronchial reactivity in subjects with mild-moderate persistent asthma
    • Riccioni G, Vecchia RD, D'Orazio N, et al. Comparison of montelukast and budesonide on bronchial reactivity in subjects with mild-moderate persistent asthma. Pulm Pharmacol Ther 2003; 16:111-114
    • (2003) Pulm Pharmacol Ther , vol.16 , pp. 111-114
    • Riccioni, G.1    Vecchia, R.D.2    D'Orazio, N.3
  • 42
    • 0041571549 scopus 로고    scopus 로고
    • Effect of zafirlukast on methacholine and ultrasonically nebulized distilled water challenge in patients with mild asthma
    • Carratu P, Morelli N, Freire AX, et al. Effect of zafirlukast on methacholine and ultrasonically nebulized distilled water challenge in patients with mild asthma. Respiration 2003; 70:249-253
    • (2003) Respiration , vol.70 , pp. 249-253
    • Carratu, P.1    Morelli, N.2    Freire, A.X.3
  • 43
    • 0033934904 scopus 로고    scopus 로고
    • Effect of pranlukast on bronchial inflammation in patients with asthma
    • Yoshida S, Ishizaki Y, Shoji T, et al. Effect of pranlukast on bronchial inflammation in patients with asthma. Clin Exp Allergy 2000; 30:1008-1014
    • (2000) Clin Exp Allergy , vol.30 , pp. 1008-1014
    • Yoshida, S.1    Ishizaki, Y.2    Shoji, T.3
  • 44
    • 0034141744 scopus 로고    scopus 로고
    • Effects of 2 weeks of treatment with fluticasone propionate 100 meg b.d. by comparison with zafirlukast 20 mg b.d. on bronchial hyper-responsiveness in patients with mild to moderate asthma
    • Westbroek J, Pasma HR. Effects of 2 weeks of treatment with fluticasone propionate 100 meg b.d. by comparison with zafirlukast 20 mg b.d. on bronchial hyper-responsiveness in patients with mild to moderate asthma. Respir Med 2000; 94:112-118
    • (2000) Respir Med , vol.94 , pp. 112-118
    • Westbroek, J.1    Pasma, H.R.2
  • 45
    • 0036220004 scopus 로고    scopus 로고
    • Role of cysteinyl leukotrienes in adenosine 5′-monophosphate induced bronchoconstriction in asthma
    • Rorke S, Jennison S, Jeffs JA, et al. Role of cysteinyl leukotrienes in adenosine 5′-monophosphate induced bronchoconstriction in asthma. Thorax 2002; 57:323-327
    • (2002) Thorax , vol.57 , pp. 323-327
    • Rorke, S.1    Jennison, S.2    Jeffs, J.A.3
  • 46
    • 0034058290 scopus 로고    scopus 로고
    • Additive bronchoprotective and bronchodilator effects with single doses of salmeterol and montelukast in asthmatic patients receiving inhaled corticosteroids
    • Dempsey OJ, Wilson AM, Sims EJ, et al. Additive bronchoprotective and bronchodilator effects with single doses of salmeterol and montelukast in asthmatic patients receiving inhaled corticosteroids. Chest 2000; 117:950-953
    • (2000) Chest , vol.117 , pp. 950-953
    • Dempsey, O.J.1    Wilson, A.M.2    Sims, E.J.3
  • 47
    • 0036301761 scopus 로고    scopus 로고
    • Effects of adding either a leukotriene receptor antagonist or low-dose theophylline to a low or medium dose of inhaled corticosteroid in patients with persistent asthma
    • Dempsey OJ, Fowler SJ, Wilson A, et al. Effects of adding either a leukotriene receptor antagonist or low-dose theophylline to a low or medium dose of inhaled corticosteroid in patients with persistent asthma. Chest 2002; 122:151-159
    • (2002) Chest , vol.122 , pp. 151-159
    • Dempsey, O.J.1    Fowler, S.J.2    Wilson, A.3
  • 48
    • 0031820252 scopus 로고    scopus 로고
    • 4-induced bronchoconstriction in patients on maintenance inhaled corticosteroid therapy
    • 4-induced bronchoconstriction in patients on maintenance inhaled corticosteroid therapy. Ann Allergy Asthma Immunol 1998; 81:43-49
    • (1998) Ann Allergy Asthma Immunol , vol.81 , pp. 43-49
    • Smith, L.J.1    Hanby, L.A.2    Lavins, R.J.3
  • 49
    • 0031057451 scopus 로고    scopus 로고
    • Effectiveness of the leukotriene receptor antagonist zafirlukast for mild-to-moderate asthma: A randomized, double-blind, placebo-controlled trial
    • Suissa S, Dennis R, Ernst P, et al. Effectiveness of the leukotriene receptor antagonist zafirlukast for mild-to-moderate asthma: a randomized, double-blind, placebo-controlled trial. Ann Intern Med 1997; 126:177-183
    • (1997) Ann Intern Med , vol.126 , pp. 177-183
    • Suissa, S.1    Dennis, R.2    Ernst, P.3
  • 50
    • 0032430610 scopus 로고    scopus 로고
    • Zafirlukast improves asthma symptoms and quality of life in patients with moderate reversible airflow obstruction
    • Nathan RA, Bernstein JA, Bielory L, et al. Zafirlukast improves asthma symptoms and quality of life in patients with moderate reversible airflow obstruction. J Allergy Clin Immunol 1998; 102:935-942
    • (1998) J Allergy Clin Immunol , vol.102 , pp. 935-942
    • Nathan, R.A.1    Bernstein, J.A.2    Bielory, L.3
  • 51
    • 0033837039 scopus 로고    scopus 로고
    • Zafirlukast improves asthma control in patients receiving high-dose inhaled corticosteroids
    • Virchow JC, Prasse A, Naya I, et al. Zafirlukast improves asthma control in patients receiving high-dose inhaled corticosteroids. Am J Respir Crit Care Med 2000; 162:578-585
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 578-585
    • Virchow, J.C.1    Prasse, A.2    Naya, I.3
  • 52
    • 0031800910 scopus 로고    scopus 로고
    • Effect of zafirlukast (Accolate) on cellular mediators of inflammation: Bronchoalveolar lavage fluid findings after segmental antigen challenge
    • Calhoun WJ, Lavins RJ, Minkwitz MC, et al. Effect of zafirlukast (Accolate) on cellular mediators of inflammation: bronchoalveolar lavage fluid findings after segmental antigen challenge. Am J Respir Crit Care Med 1998; 157:1381-1389
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 1381-1389
    • Calhoun, W.J.1    Lavins, R.J.2    Minkwitz, M.C.3
  • 53
    • 0032866048 scopus 로고    scopus 로고
    • Montelukast reduces airway eosinophilic inflammation in asthma: A randomized, controlled trial
    • Pizzichini E, Leff JA, Reiss TF, et al. Montelukast reduces airway eosinophilic inflammation in asthma: a randomized, controlled trial. Eur Respir J 1999; 14:12-18
    • (1999) Eur Respir J , vol.14 , pp. 12-18
    • Pizzichini, E.1    Leff, J.A.2    Reiss, T.F.3
  • 54
    • 0033405946 scopus 로고    scopus 로고
    • Montelukast added to inhaled beclomethasone in treatment of asthma
    • Laviolette M, Malmstrom K, Lu S, et al. Montelukast added to inhaled beclomethasone in treatment of asthma. Am J Respir Crit Care Med 1999; 160:1862-1868
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 1862-1868
    • Laviolette, M.1    Malmstrom, K.2    Lu, S.3
  • 55
    • 0037338743 scopus 로고    scopus 로고
    • Randomised controlled trial of montelukast plus inhaled budesonide versus double dose inhaled budesonide in adult patients with asthma
    • Price DR, Hernandez D, Magyar P, et al. Randomised controlled trial of montelukast plus inhaled budesonide versus double dose inhaled budesonide in adult patients with asthma. Thorax 2003; 58:211-216
    • (2003) Thorax , vol.58 , pp. 211-216
    • Price, D.R.1    Hernandez, D.2    Magyar, P.3
  • 56
    • 0033542645 scopus 로고    scopus 로고
    • Randomised, placebo controlled trial of effect of a leukotriene receptor antagonist, montelukast, on tapering inhaled corticosteroids in asthmatic patients
    • Lofdahl C-G, Reiss TF, Leff JA, et al. Randomised, placebo controlled trial of effect of a leukotriene receptor antagonist, montelukast, on tapering inhaled corticosteroids in asthmatic patients. BMJ 1999; 319:87-90
    • (1999) BMJ , vol.319 , pp. 87-90
    • Lofdahl, C.-G.1    Reiss, T.F.2    Leff, J.A.3
  • 57
    • 0033710482 scopus 로고    scopus 로고
    • Evaluation of the effects of zafirlukast 40 mg b.i.d. in addition to preexisting therapy of high-dose inhaled steroids on symptomatic patients with reversible respiratory obstruction: Preliminary data
    • Centanni S, Santus P, Casanova F, et al. Evaluation of the effects of zafirlukast 40 mg b.i.d. in addition to preexisting therapy of high-dose inhaled steroids on symptomatic patients with reversible respiratory obstruction: preliminary data. Drugs Exp Clin Res 2000; 26:133-138
    • (2000) Drugs Exp Clin Res , vol.26 , pp. 133-138
    • Centanni, S.1    Santus, P.2    Casanova, F.3
  • 58
    • 0032522735 scopus 로고    scopus 로고
    • Montelukast for chronic asthma in 6- to 14-year-old children: A randomized, double-blind trial. Pediatric Montelukast Study Group
    • Knorr B, Matz J, Bernstein JA, et al. Montelukast for chronic asthma in 6- to 14-year-old children: a randomized, double-blind trial. Pediatric Montelukast Study Group. JAMA 1998; 279:1181-1186
    • (1998) JAMA , vol.279 , pp. 1181-1186
    • Knorr, B.1    Matz, J.2    Bernstein, J.A.3
  • 59
    • 0035461065 scopus 로고    scopus 로고
    • Montelukast, a leukotriene receptor antagonist, for the treatment of persistent asthma in children aged 2 to 5 years
    • Knorr R, Franchi LM, Bisgaard H, et al. Montelukast, a leukotriene receptor antagonist, for the treatment of persistent asthma in children aged 2 to 5 years. Pediatrics 2001; 108:E48
    • (2001) Pediatrics , vol.108
    • Knorr, R.1    Franchi, L.M.2    Bisgaard, H.3
  • 60
    • 0033938854 scopus 로고    scopus 로고
    • Effectiveness and tolerability of zafirlukast for the treatment of asthma in children
    • Pearlman DS, Lampl KL, Dowling PJ Jr, et al. Effectiveness and tolerability of zafirlukast for the treatment of asthma in children. Clin Ther 2000; 22:732-747
    • (2000) Clin Ther , vol.22 , pp. 732-747
    • Pearlman, D.S.1    Lampl, K.L.2    Dowling Jr, P.J.3
  • 61
    • 0035002482 scopus 로고    scopus 로고
    • Montelukast added to budesonide in children with persistent asthma: A randomized, double-blind, crossover study
    • Simons FE, Villa JR, Lee BW, et al. Montelukast added to budesonide in children with persistent asthma: a randomized, double-blind, crossover study. J Pediatr 2001; 138: 694-698
    • (2001) J Pediatr , vol.138 , pp. 694-698
    • Simons, F.E.1    Villa, J.R.2    Lee, B.W.3
  • 62
    • 0034793255 scopus 로고    scopus 로고
    • Oral montelukast versus inhaled beclomethasone in 6- to 11-year-old children with asthma: Results of an open-label extension study evaluating long-term safety, satisfaction, and adherence with therapy
    • Maspero JF, Duenas-Meza E, Volovitz B, et al. Oral montelukast versus inhaled beclomethasone in 6- to 11-year-old children with asthma: results of an open-label extension study evaluating long-term safety, satisfaction, and adherence with therapy. Curr Med Res Opin 2001; 17:96-104
    • (2001) Curr Med Res Opin , vol.17 , pp. 96-104
    • Maspero, J.F.1    Duenas-Meza, E.2    Volovitz, B.3
  • 63
    • 0034521265 scopus 로고    scopus 로고
    • Use of montelukast in the treatment of early childhood wheezing from clinical experience with three cases
    • Ng DK, Law AK, Chau KW, et al. Use of montelukast in the treatment of early childhood wheezing from clinical experience with three cases. Respirology 2000; 5:389-392
    • (2000) Respirology , vol.5 , pp. 389-392
    • DK, N.1    Law, A.K.2    Chau, K.W.3
  • 64
    • 0037322181 scopus 로고    scopus 로고
    • A randomized trial of montelukast in respiratory syncytial virus postbronchiolitis
    • Bisgaard H. A randomized trial of montelukast in respiratory syncytial virus postbronchiolitis. Am J Respir Crit Care Med 2003; 167:379-383
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 379-383
    • Bisgaard, H.1
  • 65
    • 0042344920 scopus 로고    scopus 로고
    • Montelukast improves asthma control in asthmatic children maintained on inhaled corticosteroids
    • Phipatanakul W, Greene C, Downes SJ, et al. Montelukast improves asthma control in asthmatic children maintained on inhaled corticosteroids. Ann Allergy Asthma Immunol 2003; 91:49-54
    • (2003) Ann Allergy Asthma Immunol , vol.91 , pp. 49-54
    • Phipatanakul, W.1    Greene, C.2    Downes, S.J.3
  • 66
    • 0036172581 scopus 로고    scopus 로고
    • A randomized, double-blind trial of the effect of treatment with montelukast on bronchial hyperresponsiveness and serum eosinophilic cationic protein (ECP), soluble interleukin 2 receptor (sIL-2R), IL-4, and soluble intercellular adhesion molecule 1 (sI-CAM-1) in children with asthma
    • Stelmach I, Jerzynska J, Kuna P. A randomized, double-blind trial of the effect of treatment with montelukast on bronchial hyperresponsiveness and serum eosinophilic cationic protein (ECP), soluble interleukin 2 receptor (sIL-2R), IL-4, and soluble intercellular adhesion molecule 1 (sI-CAM-1) in children with asthma. J Allergy Clin Immunol 2002; 109:257-263
    • (2002) J Allergy Clin Immunol , vol.109 , pp. 257-263
    • Stelmach, I.1    Jerzynska, J.2    Kuna, P.3
  • 67
    • 0037441916 scopus 로고    scopus 로고
    • A randomized controlled trial of intravenous montelukast in acute asthma
    • Camargo CA Jr, Smithline HA, Malice MP, et al. A randomized controlled trial of intravenous montelukast in acute asthma. Am J Respir Crit Care Med 2003; 167:528-533
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 528-533
    • Camargo Jr, C.A.1    Smithline, H.A.2    Malice, M.P.3
  • 68
    • 18744421762 scopus 로고    scopus 로고
    • Montelukast, a leukotriene-receptor antagonist, for the treatment of mild asthma and exercise-induced bronchoconstriction
    • Leff JA, Busse WW, Pearlman D, et al. Montelukast, a leukotriene-receptor antagonist, for the treatment of mild asthma and exercise-induced bronchoconstriction. N Engl J Med 1998; 339:147-152
    • (1998) N Engl J Med , vol.339 , pp. 147-152
    • Leff, J.A.1    Busse, W.W.2    Pearlman, D.3
  • 69
    • 0036256808 scopus 로고    scopus 로고
    • Influence of zafirlukast and loratadine on exercise-induced bronchoconstriction
    • Dahlen B, Roquet A, Inman MD, et al. Influence of zafirlukast and loratadine on exercise-induced bronchoconstriction. J Allergy Clin Immunol 2002; 109:789-793
    • (2002) J Allergy Clin Immunol , vol.109 , pp. 789-793
    • Dahlen, B.1    Roquet, A.2    Inman, M.D.3
  • 70
    • 0031660267 scopus 로고    scopus 로고
    • Montelukast once daily inhibits exercise-induced bronchoconstriction in 6- to 14_year-old children with asthma
    • Kemp JP, Dockhorn RJ, Shapiro GG, et al. Montelukast once daily inhibits exercise-induced bronchoconstriction in 6- to 14_year-old children with asthma. J Pediatr 1998; 133:424-428
    • (1998) J Pediatr , vol.133 , pp. 424-428
    • Kemp, J.P.1    Dockhorn, R.J.2    Shapiro, G.G.3
  • 71
    • 0033238050 scopus 로고    scopus 로고
    • 4-receptor antagonist zafirlukast attenuates exercise-induced bronchoconstriction in children
    • 4-receptor antagonist zafirlukast attenuates exercise-induced bronchoconstriction in children. J Pediatr 1999; 134:273-279
    • (1999) J Pediatr , vol.134 , pp. 273-279
    • Pearlman, D.S.1    Ostrom, N.K.2    Bronsky, E.A.3
  • 72
    • 0035989377 scopus 로고    scopus 로고
    • The combination of single-dose montelukast and loratadine on exercise-induced bronchospasm in children
    • Peroni DG, Piacentini GL, Pietrobelli A, et al. The combination of single-dose montelukast and loratadine on exercise-induced bronchospasm in children. Eur Respir J 2002; 20:104-107
    • (2002) Eur Respir J , vol.20 , pp. 104-107
    • Peroni, D.G.1    Piacentini, G.L.2    Pietrobelli, A.3
  • 73
    • 0036142418 scopus 로고    scopus 로고
    • Improvement of aspirin-intolerant asthma by montelukast, a leukotriene antagonist: A randomized, double-blind, placebo-controlled trial
    • Dahlen SE, Malmstrom K, Nizankowska E, et al. Improvement of aspirin-intolerant asthma by montelukast, a leukotriene antagonist: a randomized, double-blind, placebo-controlled trial. Am J Respir Crit Care Med 2002; 165:9-14
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 9-14
    • Dahlen, S.E.1    Malmstrom, K.2    Nizankowska, E.3
  • 74
    • 0032950143 scopus 로고    scopus 로고
    • The effect of montelukast (MK-0476), a cysteinyl leukotriene receptor antagonist, on allergen-induced airway responses and sputum cell counts in asthma
    • Diamant Z, Grootendorst DC, Veselic-Charvat M, et al. The effect of montelukast (MK-0476), a cysteinyl leukotriene receptor antagonist, on allergen-induced airway responses and sputum cell counts in asthma. Clin Exp Allergy 1999; 29:42-51
    • (1999) Clin Exp Allergy , vol.29 , pp. 42-51
    • Diamant, Z.1    Grootendorst, D.C.2    Veselic-Charvat, M.3
  • 75
    • 0030944646 scopus 로고    scopus 로고
    • Combined antagonism of leukotrienes and histamine produces predominant inhibition of allergen-induced early and late phase airway obstruction in asthmatics
    • Roquet A, Dahlen B, Kumlin M, et al. Combined antagonism of leukotrienes and histamine produces predominant inhibition of allergen-induced early and late phase airway obstruction in asthmatics. Am J Respir Crit Care Med 1997; 155:1856-1863
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 1856-1863
    • Roquet, A.1    Dahlen, B.2    Kumlin, M.3
  • 76
    • 0031754251 scopus 로고    scopus 로고
    • Pranlukast, a cysteinyl leukotriene receptor antagonist, attenuates allergen-induced early- and late-phase bronchoconstriction and airway hyperresponsiveness in asthmatic subjects
    • Hamilton A, Faiferman I, Stober P, et al. Pranlukast, a cysteinyl leukotriene receptor antagonist, attenuates allergen-induced early- and late-phase bronchoconstriction and airway hyperresponsiveness in asthmatic subjects. J Allergy Clin Immunol 1998; 102:177-183
    • (1998) J Allergy Clin Immunol , vol.102 , pp. 177-183
    • Hamilton, A.1    Faiferman, I.2    Stober, P.3
  • 77
    • 0036251780 scopus 로고    scopus 로고
    • The efficacy of montelukast in the treatment of cat allergen-induced asthma in children
    • Phipatanakul W, Nowak-Wegrzyn A, Eggleston PA, et al. The efficacy of montelukast in the treatment of cat allergen-induced asthma in children. J Allergy Clin Immunol 2002; 109:794-799
    • (2002) J Allergy Clin Immunol , vol.109 , pp. 794-799
    • Phipatanakul, W.1    Nowak-Wegrzyn, A.2    Eggleston, P.A.3
  • 78
    • 0034089401 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial of the effect of zafirlukast on upper and lower respiratory responses to cat challenge
    • Phipatanakul W, Eggleston PA, Conover-Walker MK, et al. A randomized, double-blind, placebo-controlled trial of the effect of zafirlukast on upper and lower respiratory responses to cat challenge. J Allergy Clin Immunol 2000; 105:704-710
    • (2000) J Allergy Clin Immunol , vol.105 , pp. 704-710
    • Phipatanakul, W.1    Eggleston, P.A.2    Conover-Walker, M.K.3
  • 79
    • 0034826833 scopus 로고    scopus 로고
    • Effects of zafirlukast upon clinical, physiologic, and inflammatory responses to natural cat allergen exposure
    • Corren J, Spector S, Fuller L, et al. Effects of zafirlukast upon clinical, physiologic, and inflammatory responses to natural cat allergen exposure. Ann Allergy Asthma Immunol 2001; 87:211-217
    • (2001) Ann Allergy Asthma Immunol , vol.87 , pp. 211-217
    • Corren, J.1    Spector, S.2    Fuller, L.3
  • 80
    • 0038639212 scopus 로고    scopus 로고
    • Effects of zafirlukast on bronchial asthma and allergic rhinitis
    • Piatti G, Ceriotti L, Cavallaro G, et al. Effects of zafirlukast on bronchial asthma and allergic rhinitis. Pharmacol Res 2003; 47:541-547
    • (2003) Pharmacol Res , vol.47 , pp. 541-547
    • Piatti, G.1    Ceriotti, L.2    Cavallaro, G.3
  • 81
    • 0036627769 scopus 로고    scopus 로고
    • Efficacy and tolerability of montelukast alone or in combination with loratadine in seasonal allergic rhinitis: A multicenter, randomized, double-blind, placebo-controlled trial performed in the fall
    • Nayak AS, Philip G, Lu S, et al. Efficacy and tolerability of montelukast alone or in combination with loratadine in seasonal allergic rhinitis: a multicenter, randomized, double-blind, placebo-controlled trial performed in the fall. Ann Allergy Asthma Immunol 2002; 88:592-600
    • (2002) Ann Allergy Asthma Immunol , vol.88 , pp. 592-600
    • Nayak, A.S.1    Philip, G.2    Lu, S.3
  • 82
    • 0035987308 scopus 로고    scopus 로고
    • Montelukast for treating seasonal allergic rhinitis: A randomized, double-blind, placebo-controlled trial performed in the spring
    • Philip G, Malmstrom K, Hampel FC, et al. Montelukast for treating seasonal allergic rhinitis: a randomized, double-blind, placebo-controlled trial performed in the spring. Clin Exp Allergy 2002; 32:1020-1028
    • (2002) Clin Exp Allergy , vol.32 , pp. 1020-1028
    • Philip, G.1    Malmstrom, K.2    Hampel, F.C.3
  • 83
    • 0037326761 scopus 로고    scopus 로고
    • Randomized controlled trial evaluating the clinical benefit of montelukast for treating spring seasonal allergic rhinitis
    • van Adelsberg J, Philip G, LaForce CF, et al. Randomized controlled trial evaluating the clinical benefit of montelukast for treating spring seasonal allergic rhinitis. Ann Allergy Asthma Immunol 2003; 90:214-222
    • (2003) Ann Allergy Asthma Immunol , vol.90 , pp. 214-222
    • van Adelsberg, J.1    Philip, G.2    LaForce, C.F.3
  • 84
    • 0036627769 scopus 로고    scopus 로고
    • Efficacy and tolerability of montelukast alone or in combination with loratadine in seasonal allergic rhinitis: A multicenter, randomized, double-blind, placebo-controlled trial performed in the fall
    • Nayak AS, Philip G, Lu S, et al. Efficacy and tolerability of montelukast alone or in combination with loratadine in seasonal allergic rhinitis: a multicenter, randomized, double-blind, placebo-controlled trial performed in the fall. Ann Allergy Asthma Immunol 2002; 88:592-600
    • (2002) Ann Allergy Asthma Immunol , vol.88 , pp. 592-600
    • Nayak, A.S.1    Philip, G.2    Lu, S.3
  • 85
    • 0035987308 scopus 로고    scopus 로고
    • Montelukast for treating seasonal allergic rhinitis: A randomized, double-blind, placebo-controlled trial performed in the spring
    • Philip G, Malmstrom K, Hampel FC, et al. Montelukast for treating seasonal allergic rhinitis: a randomized, double-blind, placebo-controlled trial performed in the spring. Clin Exp Allergy 2002; 32:1020-1028
    • (2002) Clin Exp Allergy , vol.32 , pp. 1020-1028
    • Philip, G.1    Malmstrom, K.2    Hampel, F.C.3
  • 86
    • 0032109254 scopus 로고    scopus 로고
    • Co-existence of asthma and allergic rhinitis: A 23-year follow-up study of college students
    • Greisner WA 3rd, Settipane RJ, Settipane GA. Co-existence of asthma and allergic rhinitis: a 23-year follow-up study of college students. Allergy Asthma Proc 1998; 19:185-188
    • (1998) Allergy Asthma Proc , vol.19 , pp. 185-188
    • Greisner 3rd, W.A.1    Settipane, R.J.2    Settipane, G.A.3
  • 87
    • 0018834192 scopus 로고
    • Allergic and nonallergic rhinitis: Their characterization with attention to the meaning of nasal eosinophilia
    • Mullarkey MF, Hill JS, Webb DR. Allergic and nonallergic rhinitis: their characterization with attention to the meaning of nasal eosinophilia. J Allergy Clin Immunol 1980; 65:122-126
    • (1980) J Allergy Clin Immunol , vol.65 , pp. 122-126
    • Mullarkey, M.F.1    Hill, J.S.2    Webb, D.R.3
  • 88
    • 0037841802 scopus 로고    scopus 로고
    • Rhinitis and asthma: Evidence for respiratory system integration
    • Togias A. Rhinitis and asthma: evidence for respiratory system integration. J Allergy Clin Immunol 2003; 111:1171-1183
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 1171-1183
    • Togias, A.1
  • 89
    • 0026560155 scopus 로고
    • Changes in bronchial responsiveness following nasal provocation with allergen
    • Corren J, Adinoff AD, Irvin CG. Changes in bronchial responsiveness following nasal provocation with allergen. J Allergy Clin Immunol 1992; 89:611-618
    • (1992) J Allergy Clin Immunol , vol.89 , pp. 611-618
    • Corren, J.1    Adinoff, A.D.2    Irvin, C.G.3
  • 90
    • 0035096259 scopus 로고    scopus 로고
    • Nasal allergen provocation induces adhesion molecule expression and tissue eosinophilia in upper and lower airways
    • Braunstahl GJ, Overbeek SE, Kleinjan A, et al. Nasal allergen provocation induces adhesion molecule expression and tissue eosinophilia in upper and lower airways. J Allergy Clin Immunol 2001; 107:469-476
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 469-476
    • Braunstahl, G.J.1    Overbeek, S.E.2    Kleinjan, A.3
  • 91
    • 0034046903 scopus 로고    scopus 로고
    • Segmental bronchial provocation induces nasal inflammation in allergic rhinitis patients
    • Braunstahl GJ, Kleinjan A, Overbeek SE, et al. Segmental bronchial provocation induces nasal inflammation in allergic rhinitis patients. Am J Respir Crit Care Med 2000; 161: 2051-2057
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 2051-2057
    • Braunstahl, G.J.1    Kleinjan, A.2    Overbeek, S.E.3
  • 92
    • 0035447359 scopus 로고    scopus 로고
    • Segmental bronchoprovocation in allergic rhinitis patients affects mast cell and basophil numbers in nasal and bronchial mucosa
    • Braunstahl GJ, Overbeek SE, Fokkens WJ, et al. Segmental bronchoprovocation in allergic rhinitis patients affects mast cell and basophil numbers in nasal and bronchial mucosa. Am J Respir Crit Care Med 2001; 164:858-865
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 858-865
    • Braunstahl, G.J.1    Overbeek, S.E.2    Fokkens, W.J.3
  • 93
    • 0034072016 scopus 로고    scopus 로고
    • Eosinophils are a feature of upper and lower airway pathology in non-atopic asthma, irrespective of the presence of rhinitis
    • Gaga M, Lambrou P, Papageorgiou N, et al. Eosinophils are a feature of upper and lower airway pathology in non-atopic asthma, irrespective of the presence of rhinitis. Clin Exp Allergy 2000; 30:663-669
    • (2000) Clin Exp Allergy , vol.30 , pp. 663-669
    • Gaga, M.1    Lambrou, P.2    Papageorgiou, N.3
  • 95
    • 0035804276 scopus 로고    scopus 로고
    • Allergy and allergic diseases: First of two parts
    • Kay AB. Allergy and allergic diseases: first of two parts. N Engl J Med 2001; 344:30-37
    • (2001) N Engl J Med , vol.344 , pp. 30-37
    • Kay, A.B.1
  • 96
    • 0032977062 scopus 로고    scopus 로고
    • Clinical manifestations of the release of histamine and other inflammatory mediators
    • Naclerio R. Clinical manifestations of the release of histamine and other inflammatory mediators. J Allergy Clin Immunol 1999; 103:5382-5385
    • (1999) J Allergy Clin Immunol , vol.103 , pp. 5382-5385
    • Naclerio, R.1
  • 97
    • 0036970473 scopus 로고    scopus 로고
    • The effect of cysteinyl leukotrienes on growth of eosinophil progenitors from peripheral blood and bone marrow of atopic subjects
    • Braccioni F, Dorman SC, O'Byrne PM, et al. The effect of cysteinyl leukotrienes on growth of eosinophil progenitors from peripheral blood and bone marrow of atopic subjects. J Allergy Clin Immunol 2002; 110:96-101
    • (2002) J Allergy Clin Immunol , vol.110 , pp. 96-101
    • Braccioni, F.1    Dorman, S.C.2    O'Byrne, P.M.3
  • 98
    • 0028973572 scopus 로고
    • 4 induces P-selectin and sialyl Lewis(x)-dependent alterations in leukocyte kinetics in vivo
    • 4 induces P-selectin and sialyl Lewis(x)-dependent alterations in leukocyte kinetics in vivo. Circ Res 1995; 77:879-887
    • (1995) Circ Res , vol.77 , pp. 879-887
    • Kanwar, S.1    Johnston, B.2    Kubes, P.3
  • 100
    • 0036010575 scopus 로고    scopus 로고
    • 4 upregulates eosinophil adhesion via the cysteinyl leukotriene 1 receptor
    • 4 upregulates eosinophil adhesion via the cysteinyl leukotriene 1 receptor. J Allergy Clin Immunol 2002; 109:676-680
    • (2002) J Allergy Clin Immunol , vol.109 , pp. 676-680
    • Nagata, M.1    Saito, K.2    Tsuchiya, K.3
  • 101
    • 0031283045 scopus 로고    scopus 로고
    • 4) on motility of isolated normodense human eosinophils and neutrophils
    • 4) on motility of isolated normodense human eosinophils and neutrophils. Adv Exp Med Biol 1997; 400B:699-706
    • (1997) Adv Exp Med Biol , vol.400 B , pp. 699-706
    • Spada, C.S.1    Krauss, A.H.2    Nieves, A.L.3
  • 102
    • 0037018105 scopus 로고    scopus 로고
    • Cysteinyl leukotrienes and uridine diphosphate induce cytokine generation by human mast cells through an interleukin 4-regulated pathway that is inhibited by leukotriene receptor antagonists
    • Mellor EA, Austen KF, Boyce JA. Cysteinyl leukotrienes and uridine diphosphate induce cytokine generation by human mast cells through an interleukin 4-regulated pathway that is inhibited by leukotriene receptor antagonists. J Exp Med 2002; 195:583-592
    • (2002) J Exp Med , vol.195 , pp. 583-592
    • Mellor, E.A.1    Austen, K.F.2    Boyce, J.A.3
  • 103
    • 0037338372 scopus 로고    scopus 로고
    • Anti-inflammatory effects of high-dose montelukast in an animal model of acute asthma
    • Wu AY, Chik SC, Chan AW, et al. Anti-inflammatory effects of high-dose montelukast in an animal model of acute asthma. Clin Exp Allergy 2003; 33:359-366
    • (2003) Clin Exp Allergy , vol.33 , pp. 359-366
    • Wu, A.Y.1    Chik, S.C.2    Chan, A.W.3
  • 104
    • 0032754963 scopus 로고    scopus 로고
    • Effects of ONO-1078 (pranlukast) on cytokine production in peripheral blood mononuclear cells of patients with bronchial asthma
    • Tohda Y, Nakahara H, Kubo H, et al. Effects of ONO-1078 (pranlukast) on cytokine production in peripheral blood mononuclear cells of patients with bronchial asthma. Clin Exp Allergy 1999; 29:1532-1536
    • (1999) Clin Exp Allergy , vol.29 , pp. 1532-1536
    • Tohda, Y.1    Nakahara, H.2    Kubo, H.3
  • 106
    • 0032845544 scopus 로고    scopus 로고
    • NO in exhaled air of asthmatic children is reduced by the leukotriene receptor antagonist montelukast
    • Bisgaard H, Loland L, Oj JA. NO in exhaled air of asthmatic children is reduced by the leukotriene receptor antagonist montelukast. Am J Respir Crit Care Med 1999; 160:1227-1231
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 1227-1231
    • Bisgaard, H.1    Loland, L.2    Oj, J.A.3
  • 107
    • 0033376698 scopus 로고    scopus 로고
    • Exhaled nitric oxide before and after montelukast sodium therapy in school-age children with chronic asthma: A preliminary study
    • Bratton DL, Lanz MJ, Miyazawa N, et al. Exhaled nitric oxide before and after montelukast sodium therapy in school-age children with chronic asthma: a preliminary study. Pediatr Pulmonol 1999; 28:402-407
    • (1999) Pediatr Pulmonol , vol.28 , pp. 402-407
    • Bratton, D.L.1    Lanz, M.J.2    Miyazawa, N.3
  • 108
    • 0037246364 scopus 로고    scopus 로고
    • Roles of cysteinyl leukotrienes in airway inflammation, smooth muscle function, and remodeling
    • discussion S34-S16
    • Holgate ST, Peters-Golden M, Panettieri RA, et al. Roles of cysteinyl leukotrienes in airway inflammation, smooth muscle function, and remodeling. J Allergy Clin Immunol 2003; 111:518-534; discussion S34-S16
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 518-534
    • Holgate, S.T.1    Peters-Golden, M.2    Panettieri, R.A.3
  • 109
    • 0037824477 scopus 로고    scopus 로고
    • Effects of cysteinyl leukotrienes in small human bronchus and antagonist activity of montelukast and its metabolites
    • Mechiche H, Naline E, Candenas L, et al. Effects of cysteinyl leukotrienes in small human bronchus and antagonist activity of montelukast and its metabolites. Clin Exp Allergy 2003; 33:887-894
    • (2003) Clin Exp Allergy , vol.33 , pp. 887-894
    • Mechiche, H.1    Naline, E.2    Candenas, L.3
  • 110
    • 0035844001 scopus 로고    scopus 로고
    • 1- and cysteinyl leukotriene 1-receptor blockade in human bronchus
    • 1- and cysteinyl leukotriene 1-receptor blockade in human bronchus. Life Sci 2001; 68:2825-2834
    • (2001) Life Sci , vol.68 , pp. 2825-2834
    • Ruck, L.M.1    Rizzo, C.A.2    Anthes, J.C.3
  • 111
    • 0023158760 scopus 로고
    • Modulation of fibroblast proliferation by sulfidopeptide leukotrienes: Effect of indomethacin
    • Baud L, Perez J, Denis M, et al. Modulation of fibroblast proliferation by sulfidopeptide leukotrienes: effect of indomethacin. J Immunol 1987; 138:1190-1195
    • (1987) J Immunol , vol.138 , pp. 1190-1195
    • Baud, L.1    Perez, J.2    Denis, M.3
  • 112
    • 0023222346 scopus 로고
    • Regulation of macrophage-derived fibroblast growth factor release by arachidonate metabolites
    • Phan SH, McGarry BM, Loeffler KM, et al. Regulation of macrophage-derived fibroblast growth factor release by arachidonate metabolites. J Leukoc Biol 1987; 42:106-113
    • (1987) J Leukoc Biol , vol.42 , pp. 106-113
    • Phan, S.H.1    McGarry, B.M.2    Loeffler, K.M.3
  • 113
    • 0023820012 scopus 로고
    • 4 to rat lung fibroblasts and stimulation of collagen synthesis in vitro
    • 4 to rat lung fibroblasts and stimulation of collagen synthesis in vitro. Biochemistry 1988; 27:2846-2853
    • (1988) Biochemistry , vol.27 , pp. 2846-2853
    • Phan, S.H.1    McGarry, B.M.2    Loeffler, K.M.3
  • 114
    • 0037080719 scopus 로고    scopus 로고
    • Protection from pulmonary fibrosis in leukotriene-deficient mice
    • Peters-Golden M, Bailie M, Marshall T, et al. Protection from pulmonary fibrosis in leukotriene-deficient mice. Am J Respir Crit Care Med 2002; 165:229-235
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 229-235
    • Peters-Golden, M.1    Bailie, M.2    Marshall, T.3
  • 115
    • 0036140825 scopus 로고    scopus 로고
    • A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model
    • Henderson WR, Tang LO, Chu SJ, et al. A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model. Am J Respir Crit Care Med 2002; 165:108-116
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 108-116
    • Henderson, W.R.1    Tang, L.O.2    Chu, S.J.3
  • 116
    • 0032161343 scopus 로고    scopus 로고
    • 4 on human airway smooth muscle cell proliferation, matrix expression, and contraction in vitro: Differential sensitivity to cysteinyl leukotriene receptor antagonists
    • 4 on human airway smooth muscle cell proliferation, matrix expression, and contraction in vitro: differential sensitivity to cysteinyl leukotriene receptor antagonists. Am J Respir Cell Mol Biol 1998; 19:453-461
    • (1998) Am J Respir Cell Mol Biol , vol.19 , pp. 453-461
    • Panettieri, R.A.1    Tan, E.M.2    Ciocca, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.