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Volumn 283, Issue 5401, 1999, Pages 541-543

Reciprocal inhibitory connections and network synchrony in the mammalian thalamus

Author keywords

[No Author keywords available]

Indexed keywords

ABSENCE; ARTICLE; CELL SYNCHRONIZATION; CHANNEL GATING; GABAERGIC TRANSMISSION; INHIBITORY POSTSYNAPTIC POTENTIAL; LATERAL RETICULAR NUCLEUS; NERVE CELL NETWORK; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; THALAMUS; VOLTAGE CLAMP;

EID: 0033593590     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.283.5401.541     Document Type: Article
Times cited : (297)

References (30)
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    • note
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    • note
    • 2, 10 mM EGTA, 10 mM Hepes (pH 7.3)] and had resistances of 2.0 to 3.3 megohms. IPSCs were filtered at 1 kHz and stored on VCR tape (Neuro-corder, Cygnus Technology, Delaware Water Gap, PA). Spontaneous events were digitized with Axotape, version 2 (Axon Instruments), then were sorted and analyzed using Detector (version 4.8, J. R. Huguenard), Scan (J. R. Dempster), and Metatape (version 14.0, J. R. Huguenard). Unless otherwise noted, all statistical values indicate results of Student's t test.
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    • eIPSCs were obtained by stimulating RTN with a bipolar tungsten electrode. Stimuli were 1.5 times threshold (1.5 to 4 mA; 80 to 200 μs).
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    • note
    • BMI (n = 18 slices) or picrotoxin (n = 4) enhanced oscillatory output when applied locally (500 μM via pressure application pipette) to RTN (137 ± 13% of control, P < 0.0001), but not VB (13 ± 2% of control, P < 0.01).
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    • We thank C. Ferguson and J. Steinmiller for technical assistance and L. L. Firestone, R. W. Olsen, P. S. Buckmaster, N. A. Lambert, and D. A. Prince for support, encouragement, and helpful comments. Supported by NIH grants NS06477, NS34774, AA10422, and GM52035; the Pimley Research Fund; and the University Anesthesiology and Critical Care Medicine Foundation. Additional information may be obtained at http://tonto.stanford.edu/~john.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.