RNA aptamers targeting the cell death inhibitor CED-9 induce cell killing in Caenorhabditis elegans

Journal of Biological Chemistry

Volumn 281, Issue 14, 2006, Pages 9137-9144

  Yang, Chonglin ^a   Yan, Nieng ^b   Parish, Jay ^a,c   Wang, Xiaochen ^a   Shi, Yigong ^b   Xue, Ding ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b PRINCETON UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELL CULTURE; DISEASES; DRUG DOSAGE; ENZYME INHIBITION; NEUROLOGY;

APTAMERS; CAENORHABDITIS ELEGANS; SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT (SELEX);

RNA;

APTAMER; CASPASE 3; PROTEIN BCL 2; PROTEIN CED 9; PROTEIN EGL 1; PROTEIN R 92; PROTEIN R 97; RNA; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; CAENORHABDITIS ELEGANS PROTEIN; CALCIUM BINDING PROTEIN; CED 4 PROTEIN, C ELEGANS; CED 9 PROTEIN, C ELEGANS; CED-4 PROTEIN, C ELEGANS; CED-9 PROTEIN, C ELEGANS; ONCOPROTEIN;

ARTICLE; BINDING AFFINITY; CAENORHABDITIS ELEGANS; CELL DEATH; CELL KILLING; CHEMICAL ANALYSIS; IN VITRO STUDY; IN VIVO STUDY; NERVE CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA ISOLATION; ANIMAL; APOPTOSIS; BINDING SITE; BIOSYNTHESIS; COMBINATORIAL CHEMISTRY; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE;

CAENORHABDITIS ELEGANS;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; APTAMERS, NUCLEOTIDE; BASE SEQUENCE; BINDING SITES; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CALCIUM-BINDING PROTEINS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTO-ONCOGENE PROTEINS; SELEX APTAMER TECHNIQUE;

EID: 33646905186     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M511742200     Document Type: Article

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