Downstream molecular events in the altered profiles of lysophosphatidic acid-induced cAMP in senescent human diploid febroblast

Experimental and Molecular Medicine

Volumn 38, Issue 2, 2006, Pages 134-143

  Jang, Ik Soon ^a   Rhim, Ji Heon ^a   Sang, Chul Park ^a   Yeo, Eui Ju ^b  

^a Seoul National University College of Medicine   (South Korea)

^b Gachon University College of Medicine   (South Korea)

Author keywords

Aging; Cyclic AMP response element binding protein; Cyclic AMP dependent protein kinases; Cyclooxygenase 2; Lysophosphatidic acid; Proto oncogene proteins c fos

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BISINDOLYLMALEIMIDE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLOOXYGENASE 2; LUCIFERASE; LYSOPHOSPHATIDIC ACID; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROTEIN C FOS; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; REGULATOR PROTEIN;

AGED; ALPHA CHAIN; ARTICLE; CONTROLLED STUDY; DIPLOIDY; DNA RESPONSIVE ELEMENT; DOWNSTREAM PROCESSING; DRUG MECHANISM; ENZYME ACTIVITY; FIBROBLAST; GENE CONTROL; GENE EXPRESSION; HUMAN; HUMAN CELL; NEWBORN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SENESCENCE;

EID: 33646873040     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2006.17     Document Type: Article

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