Phenylephrine induces activation of CREB in adult rat cardiac myocytes through MSK1 and PKA signaling pathways

Journal of Molecular and Cellular Cardiology

Volumn 37, Issue 5, 2004, Pages 1001-1011

  Markou, Thomais ^a,b   Hadzopoulou Cladaras, Margarita ^b   Lazou, Antigone ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b Laboratory of Animal Physiology   (Greece)

Author keywords

Adrenergic agonist; Adult rat cardiac myocytes; ANF; CREB; Hypertrophy; MAPK; MSK1; Transcription factor

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; ALPHA 1 ADRENERGIC RECEPTOR; ATRIAL NATRIURETIC FACTOR; BETA ADRENERGIC RECEPTOR; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHENYLEPHRINE; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; DNA BINDING; ENZYME ACTIVATION; ENZYME INHIBITION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE WALL; MALE; MARKER GENE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT;

ADRENERGIC AGONISTS; ANIMALS; ATRIAL NATRIURETIC FACTOR; CARDIOMEGALY; CREB-BINDING PROTEIN; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GENE EXPRESSION REGULATION; IMMUNOPRECIPITATION; INDOLES; ISOQUINOLINES; MITOGEN-ACTIVATED PROTEIN KINASE 3; MYOCYTES, CARDIAC; NUCLEAR PROTEINS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENYLEPHRINE; PHOSPHORYLATION; RATS; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, ADRENERGIC, BETA; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; RNA, MESSENGER; SIGNAL TRANSDUCTION; SULFONAMIDES; TRANS-ACTIVATORS;

EID: 7444264191     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2004.08.002     Document Type: Article

References (35)

1. P. Sugden, and A. Clerk Cellular mechanisms of cardiac hypertrophy J. Mol. Med. 76 1980 725 742
2. 1- mediated response J. Biol. Chem. 265 1990 13809 13817
3. A. Clerk, M. Bogoyevitch, M. Andersson, and P. Sugden Differential activation of protein kinase C isofroms by endothelin-1 and phenylephrine and subsequent stimulation of p42 and p44 mitogen-activated protein kinases in ventricular myocytes cultured from neonatal rat hearts J. Biol. Chem. 269 1994 32848 32857
4. M. Bogoyevitch, P. Glennon, M. Andersson, A. Clerk, A. Lazou, and C. Marshall Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes J. Biol. Chem. 269 1994 1110 1119
5. 1-adrenergic receptor and Ras activation is associated with in vitro and in vivo cardiac hypertrophy J. Biol. Chem. 272 1997 14057 14061
6. A. Clerk, A. Michael, and P. Sugden Stimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine; a role in cardiac myocyte hypertrophy? J. Cell Biol. 142 1998 523 535
7. T. Markou, and A. Lazou Phosphorylation and activation of mitogen- and stress-activated protein kinase-1 in adult rat cardiac myocytes by G-protein-coupled receptor agonists requires both extracellular signal-regulated kinase and p38 mitogen-activated protein kinase Biochem. J. 365 2002 757 763
8. M. Deak, A. Clifton, J. Lucocq, and D. Alessi Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB EMBO J. 17 1998 4426 4441
9. S. Arthur, and P. Cohen MSK1 is required for CREB phosphorylation in response to mitogens in embryonic stem cells FEBS Lett. 482 2000 44 48
10. G. Wiggin, A. Soalaga, J. Foster, V. Murray-Tait, P. Cohen, and J. Arthur MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF-1 in fibroblasts Mol. Cell. Biol. 22 2002 2871 2881
11. J. Lee, J. Laydon, P. McDonnell, T. Gallagher, S. Kumar, and D. Green A protein kinase involved in the regulation of inflammatory cytokine biosynthesis Nature 372 1994 739 746
12. A. Shaywitz, and M. Greenberg CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals Annu. Rev. Biochem. 68 1999 821 861
13. A. Snowden, and N. Perkins Cell cycle regulation of the transcriptional coactivators p300 and CREB-binding protein Biochem. Pharmacol. 55 1998 1947 1954
14. G. Gonzalez, and M. Montminy Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133 Cell 59 1989 675 680
15. D. Ginty, A. Bonni, and M. Greenberg Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB Cell 77 1994 713 725
16. M. Caivano, and P. Cohen Role of the mitogen-activated protein kinase cascades in mediating lipopolysaccharide induction of cyclooxygenase-2 and IL-1β in RAW264 macrophages J. Immunol. 164 2000 3018 3025
17. M. Sheng, M. Thompson, and M. Greenberg CREB: a Ca(2+)-regulated transcription factor phosphorylated by calmodulin-dependent kinases Science 252 1991 1427 1430
18. J. Xing, D. Ginty, and M. Greenberg Coupling of the Ras-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase Science 273 1996 959 969
19. Y. Tan, J. Rouse, A. Zhang, S. Cariati, P. Cohen, and M. Comb FGF and stress regulate CREB and ATF-1 via a pathway involving p38 MAP kinase and MAPKAP kinase-2 EMBO J. 15 1996 4629 4642
20. F. Müller, J. Neumann, and W. Schmitz Transcriptional regulation by cAMP in the heart Mol. Cell. Biochem. 212 2000 11 17
21. R. Fentzke, C. Korcarz, R. Lang, H. Lin, and J. Leiden Dilated cardiomyopathy in transgenic mice expressing a dominant-negative CREB transcription factor in the heart J. Clin. Invest. 101 1998 2415 2426
22. P. Goldspink, and B. Russell Physiological role of phosphorylation of the cyclic AMP response element binding protein in rat cardiac nuclei Cell Tissue Res. 285 1996 379 385
23. F. Müller, P. Bokník, J. Knapp, B. Linck, H. Lüss, and J. Neumann Activation and inactivation of cAMP-response element-mediated transcription in cardiac myocytes Cardiovasc. Res. 52 2001 95 102
24. J. Harrison, P. Sugden, and A. Clerk Endothelin-1 promotes phosphorylation of CREB transcription factor in primary cultures of neonatal cardiac myocytes: implications for the regulation of c-jun expression Biochim. Biophys. Acta 1644 2004 17 25
25. J. Dignam, R. Lebowvitz, and R. Roeder Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei Nucleic Acids Res. 11 1983 1475 1489
26. S. Davies, H. Reddy, M. Caivano, and P. Cohen Specificity and mechanism of action of some commonly used protein kinase inhibitors Biochem. J. 351 2000 95 105
27. J. Chrivia, R. Kwok, N. Lamb, M. Hagiwara, M. Montminy, and R. Goodman Phosphorylated CREB binds specifically to the nuclear protein CBP Nature 365 1993 855 859
28. T. Cornelius, S. Holmer, F. Müller, G. Riegger, and H. Schunkert Regulation of the rat atrial natriuretic peptide gene after acute imposition of left ventricular pressure overload Hypertension 30 1997 1348 1355
29. P. Goldspink, and B. Russell The cAMP response element binding protein is expressed and phosphorylated in cardiac myocytes Circ. Res. 74 1994 1042 1049
30. F. Müller, P. Bokník, A. Horst, J. Knapp, B. Linck, and W. Schmitz cAMP response element binding protein is expressed and phosphorylated in the human heart Circulation 92 1995 2041 2043
31. D. Valks, S. Cook, F. Pham, P. Morrison, A. Clerk, and P. Sugden Phenylephrine promotes phosphorylation of Bad in cardiac myocytes through the extracellular signal-regulated kinases 1/2 and protein kinase A J. Mol. Cell. Cardiol. 34 2002 749 763
32. D. Parker, U. Jhala, I. Radhakrishman, M. Yaffe, C. Reyes, and A. Shulman Analysis of an activator:coactivator complex reveals an essential role for secondary structure in transcriptional activation Mol. Cell 2 1998 353 359
33. J. Richards, H. Bachinger, R. Goodman, and R. Brennan Analysis of the structural properties of cAMP-responsive element-binding protein (CREB) and phosphorylated CREB J. Biol. Chem. 271 1996 13716 13723
34. R. Gusterson, B. Brar, D. Faulkes, A. Giordano, J. Chrivia, and D. Latchman The transcriptional co-activators CREB-binding protein (CBP) and p300 are activated via phenylephrine through the p42/44 MAPK cascade J. Biol. Chem. 277 2002 2517 2524
35. A. Rosenweig, T. Halazonetis, J. Seidman, and C. Seidman Proximal regulatory domains of rat atrial natriuretic factor gene Circulation 84 1991 1256 1265