Lysophosphatidic acid receptors

Molecular Pharmacology

Volumn 58, Issue 6, 2000, Pages 1188-1196

  Contos, James J A ^a   Ishii, Isao ^a   Chun, Jerold ^a  

^a San Diego   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; LYSOPHOSPHATIDIC ACID;

ANGIOGENESIS; ANIMAL CELL; CONFORMATIONAL TRANSITION; DRUG RECEPTOR BINDING; GENE EXPRESSION REGULATION; MYELINATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; RECEPTOR AFFINITY; SHORT SURVEY; THROMBOCYTE ACTIVATION; WOUND HEALING;

EID: 0033669622     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.58.6.1188     Document Type: Short Survey

References (56)

1. A rat G protein-coupled receptor selectively expressed in myelin-forming cells
2. Edg-2 in myelin-forming cells: Isoforms, genomic mapping, and exclusion in Charcet-Marie-Tooth Disease
3. Characterization of a novel subtype of human G protein-coupled receptor for lysophosphatidic acid
4. Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids
5. Recombinant human G protein-coupled lysophosphatidic acid receptors mediate intracellular calcium mobilization
6. Molecular cloning of the human Edg2 protein and its identification as a functional cellular receptor for lysophosphatidic acid
7. Molecular cloning and characterization of a novel human G-protoin-coupled receptor, EDG7, for lysophosphatidic acid
8. G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly
9. Lysophospholipid receptors: Implications for neural signaling
10. A growing family of receptor genes for lysophosphatidic acid (LPA) and other lysophosphalipids (LPs)
11. The varitint-waddler mouse: A dominant mutation in Mus Musculus
12. Complete cDNA sequence, genomic structure, and chromosomal localization of the LPA receptor gene, IpA1/vzg-1/Gpcr26
13. Genomic characterization of the lysophosphatidic acid receptor gene, Ip(A2)/Edg4, and identification of a frameshift mutation in a previously characterized cDNA
14. Requirement for the IpA1 lysophosphatidic acid receptor gene in normal sucking behavior
15. Lysophosphatidic acid stimulates neurotransmitter-like conductance that precede GABA and L-Glutamate in early, presumptive cortical neuroblasts
16. The effect of active serum albumin on PC12 cells: I. Neurite retraction and activation of the phosphoinositide second messenger system
17. The bioactive phospholipid lysophosphatidic acid is released from activated platelets
18. Edg-2/Vzg-1 couples to the yeast pheromone response pathway selectively in response to lysophosphatidic acid
19. Cell signalling through guanine-nucleotide-binding regulatory proteins (G proteins) and phospholipases
20. Peptide and lipid growth factors decrease cisdiamminedichloroplatinum-induced cell death in human ovarian cancer cells
21. A single receptor encoded by vzg-1/lpA1/ edg-2 couples to G proteins and mediates multiple cellular responses to lysophosphatidic acid
22. Lysophosphatidic acid (LPA) is a novel extracellular regulator of cortical neuroblast morphology
23. Overexpression of edg-2/vzg-1 induces apoptosis and anoikis in ovarian cancer cells in a lysophosphatidic acid-independent manner
24. Distinctive expression and functions of the type 4 endothelial differentiation gene-encoded G protein-coupled receptor for lysophosphatidic acid in ovarian cancer
25. Molecular cloning of a high-affinity receptor for the growth factor-like lipid mediator lysophosphatidic acid from Xenopus oocytes
26. Molecular cloning and functional characterization of a lysophosphatidic acid receptor expressed in the developing cerebral cortex
27. Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex
28. Characterization of a receptor subtype-selective lysophosphatidic acid mimetic
29. Cytogenetic heterogeneity in t(11;19) acute leukemia: Clinical, hematological and cytogenetic analyses of 48 patients - Updated published cases and 16 new observations
30. Characterization of a novel sphingosine 1-phosphate receptor, Edg-8
31. Molecular cloning and characterization of a lysophosphatidic acid receptor, Edg-7, expressed in prostate
32. Functional comparisons of the lysophosphatidic acid receptors, LPA1NZG-1/EDG-2, LPA2/EDG-4 and LPA3/ EDG-7 in neuronal cell lines using a retrovirus expression system
33. Lysophosphatidic acid induces neuronal shape changes via a novel, receptor-mediated signaling pathway: Similarity to thrombin action
34. Thrombin receptor activation causes rapid neural cell rounding and neurite retraction independent of classic second messengers
35. Identification and genetic mapping of a new polycystic kidney disease on mouse chromosome 8
36. Lysophosphatidic acid stimulates the G-pretein-coupled receptor EDG-1 as a low affinity agonist
37. Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1
38. Cloning, characterization, and chromosomal localization of recl.3, a member of the Gprotein-coupled receptor family highly expressed in brain
39. Bioactive lysophospholipids and their G protein-coupled recepters
40. Lysophosphatidic acid: G-protein signalling and cellular responses
41. Growth factor-like action of phosphatidic acid
42. Lysophosphatidic acid induces urokinase secretion by ovarian cancer cells
43. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
44. Vacillans, a neurological mutant in the house mouse linked to brown
45. Roles of sphingosine-1-phosphate in cell growth, differentiation, and death
46. Lysophosphatidates bound to serum albumin activate membrane currents in Xenopus oocytes and neurite retraction in PC12 pheochromocytoma cells
47. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
48. Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6
49. Lysophosphatidate-induced cell proliferation: Identification and dissection of signaling pathways mediated by G proteins
50. Schwann cell survival mediated by the signaling phospholipid lysophosphatidic acid
51. Lysophosphatidic acid receptor gene vzglpA1/edg-2 is expressed by mature oligodendrocytes during myelination in the postnatal murine brain
52. Malignant effusions contain lysophosphatidic acid (LPA)-like activity
53. Lysophospholipids activate ovarian and breast cancer cells
54. Characterization of an ovarian cancer activating factor in ascites from ovarian cancer patients
55. Comparative analysis of three murine G-protein coupled receptors activated by sphingosine-1phosphate
56. Sphingosine 1-phosphate signalling through the G-protein-coupled receptor Edg-1