α-Latrotoxin induces exocytosis by inhibition of voltage-dependent K + channels and by stimulation of L-type Ca 2+ channels via latrophilin in β-cells

Journal of Biological Chemistry

Volumn 281, Issue 9, 2006, Pages 5522-5531

  Lajus, Sophie ^a   Vacher, Pierre ^b   Huber, Denise ^c   Dubois, Mathilde ^a   Benassy, Marie Noëlle ^a   Ushkaryov, Yuri ^d   Lang, Jochen ^a  

^a INSTITUT EUROPÉEN DE CHIMIE ET BIOLOGIE   (France)

^b INSERM   (France)

^c UNIVERSITY OF GENEVA   (Switzerland)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EXOCYTOSIS; LATROTOXIN; SPIDER VENOM;

BINDING ENERGY; BIOLOGICAL MEMBRANES; CALCIUM; DEPOLYMERIZATION; INSULIN; IONS; POTASSIUM; TOXIC MATERIALS;

CELLS;

ALPHA LATROTOXIN; CALCIUM; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; IBERIOTOXIN; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; INSULIN; PHOSPHOLIPASE C; PHOSPHOLIPASE C INHIBITOR; POTASSIUM CHANNEL; PROTEIN KINASE C INHIBITOR; VOLTAGE GATED POTASSIUM CHANNEL; ALPHA LATROTOXIN RECEPTOR; ALPHA-LATROTOXIN; ALPHA-LATROTOXIN RECEPTOR; PEPTIDE; RECEPTOR; RECOMBINANT PROTEIN; SPIDER VENOM;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CARBOXY TERMINAL SEQUENCE; CHANNEL GATING; CONTROLLED STUDY; DRUG INHIBITION; EXOCYTOSIS; MEMBRANE DEPOLARIZATION; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; RAT; REPOLARIZATION; ANIMAL; CELL LINE; CELL MEMBRANE POTENTIAL; CYTOLOGY; CYTOPLASM VESICLE; DRUG EFFECT; GENETICS; HAMSTER; HUMAN; METABOLISM; MOUSE; PANCREAS ISLET BETA CELL; PATCH CLAMP; PHYSIOLOGY;

ARANEAE;

ANIMALS; CALCIUM; CALCIUM CHANNELS, L-TYPE; CELL LINE; CRICETINAE; CYTOPLASMIC VESICLES; EXOCYTOSIS; HUMANS; INSULIN-SECRETING CELLS; MEMBRANE POTENTIALS; MICE; PATCH-CLAMP TECHNIQUES; PEPTIDES; PHOSPHOLIPASE C; POTASSIUM CHANNELS, VOLTAGE-GATED; RATS; RECEPTORS, PEPTIDE; RECOMBINANT PROTEINS; SPIDER VENOMS;

EID: 33646825244     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M510528200     Document Type: Article

References (62)

1. Ushkaryov, Y. A., Volynski, K. E., and Ashton, A. C. (2004) Toxicon 43, 527-542
2. Südhof, T. C. (2001) Annu. Rev. Neurosci. 24, 933-962
3. Lelianova, V. G., Davletov, B. A., Sterling, A., Rahman, M. A., Grishin, E. V., Totty, N. F., and Ushkaryov, Y. A. (1997) J. Biol. Chem. 272, 21504-21508
4. Krasnoperov, V. G., Bittner, M. A., Beavis, R., Kuang, Y., Salnikow, K. V., Chepurny, O. G., Little, A. R., Plotnikov, A. N., Wu, D., Holz, R. W., and Petrenko, A. G. (1997) Neuron 18, 925-937
5. Krasnoperov, V., Bittner, M. A., Mo, W., Buryanovsky, L., Neubert, T. A., Holz, R. W., Ichtchenko, K., and Petrenko, A. G. (2002) J. Biol. Chem. 277, 35887-35895
6. Orlova, E. V., Rahman, M. A., Gowen, B., Volynski, K. E., Ashton, A. C., Manser, C., van Heel, M., and Ushkaryov, Y. A. (2000) Nat. Struct. Biol. 7, 48-53
7. Krasnoperov, V., Bittner, M. A., Holz, R. W., Chepurny, O., and Petrenko, A. G. (1999) J. Biol. Chem. 274, 3590-3596
8. Sugita, S., Ichtchenko, K., Khvotchev, M., and Südhof, T. C. (1998) J. Biol. Chem. 273, 32715-32724
9. Hlubek, M. D., Stuenkel, E. L., Krasnoperov, V. G., Petrenko, A. G., and Holz, R. W. (2000) Mol. Pharmacol. 57, 519-528
10. Bittner, M. A., and Holz, R. W. (2000) J. Biol. Chem. 275, 25351-25357
11. Ashton, A. C., Volynski, K. E., Lelianova, V. G., Orlova, E. V., Van Renterghem, C., Canepari, M., Seagar, M., and Ushkaryov, Y. A. (2001) J. Biol. Chem. 276, 44695-44703
12. Volynski, K. E., Capogna, M., Ashton, A. C., Thomson, D., Orlova, E. V., Manser, C. F., Ribchester, R. R., and Ushkaryov, Y. A. (2003) J. Biol. Chem. 278, 31058-31066
13. Capogna, M., Volynski, K. E., Emptage, N. J., and Ushkaryov, Y. A. (2003) J. Neurosci. 23, 4044-4053
14. Tsang, C. W., Elrick, D. B., and Charlton, M. P. (2000) J. Neurosci. 20, 8685-8692
15. Volynski, K. E., Silva, J. P., Lelianova, V. G., Atiqur Rahman, M., Hopkins, C., and Ushkaryov, Y. A. (2004) EMBO J. 23, 4423-4433
16. Lang, J., Ushkaryov, Y., Grasso, A., and Wollheim, C. B. (1998) EMBO J. 17, 648-657
17. Lang, J. (1999) Eur. J. Biochem. 259, 3-17
18. Rorsman, P. (1997) Diabetologia 40, 487-495
19. Henquin, J. (2000) Diabetes 49, 1751-1760
20. Minami, K., Yano, H., Miki, T., Nagashima, K., Wang, C. Z., Tanaka, H., Miyazaki, J. I., and Seino, S. (2000) Am. J. Physiol. 279, E773-E781
21. Volynski, K. E., Meunier, F. A., Lelianova, V. G., Dudina, E. E., Volkova, T. M., Rahman, M. A., Manser, C., Grishin, E. V., Dolly, J. O., Ashley, R. H., and Ushkaryov, Y. A. (2000) J. Biol. Chem. 275, 41175-41183
22. Zhang, H., Kelley, W. L., Chamberlain, L. H., Burgoyne, R. D., and Lang, J. (1999) J. Cell Sci. 112, 1345-1351
23. Boal, F., Zhang, H., Tessier, C., Scotti, P. A., and Lang, J. (2004) Biochemistry 43, 16212-16223
24. Machado, J. D., Morales, A., Gomez, J. F., and Borges, R. (2001) Mol. Pharmacol. 60, 514-520
25. Sorin, B., Goupille, O., Vacher, A. M., Paly, J., Djiane, J., and Vacher, P. (1998) J. Biol. Chem. 273, 28461-28469
26. Davletov, B. A., Shamotienko, O. G., Lelianova, V. G., Grishin, E. V., and Ushkaryov, Y. A. (1996) J. Biol. Chem. 271, 23239-23245
27. Sekine, N., Ullrich, S., Regazzi, R., Pralong, W. F., and Wollheim, C. B. (1996) Endocrinology 137, 1841-1850
28. Tsuboi, T., da Silva Xavier, G., Holz, G. G., Jouaville, L. S., Thomas, A. P., and Rutter, G. A. (2003) Biochem. J. 369, 287-299
29. Fujiwara, K., Maekawa, F., and Yada, T. (2005) Am. J. Physiol. 289, E670-E677
30. Sheu, L., Pasyk, E. A., Ji, J., Huang, X., Gao, X., Varoqueaux, F., Brose, N., and Gaisano, H. Y. (2003) J. Biol. Chem. 278, 27556-27563
31. Gschwendt, M., Dieterich, S., Rennecke, J., Kittstein, W., Mueller, H. J., and Johannes, F. J. (1996) FEBS Lett. 392, 77-80
32. Davies, S. P., Reddy, H., Caivano, M., and Cohen, P. (2000) Biochem. J. 351, 95-105
33. Lang, J., Fukuda, M., Zhang, H., Mikoshiba, K., and Wollheim, C. B. (1997) EMBO J. 16, 5837-5846
34. Gerber, S. H., and Sudhof, T. C. (2002) Diabetes 51, S3-11
35. Jing, X., Li, D. Q., Olofsson, C. S., Salehi, A., Surve, V. V., Caballero, J., Ivarsson, R., Lundquist, I., Pereverzev, A., Schneider, T., Rorsman, P., and Renstrom, E. (2005) J. Clin. Invest. 115, 146-154
36. Yang, S. N., and Berggren, P. O. (2005) Am. J. Physiol. 288, E16-E28
37. Liu, J., and Misler, S. (1998) J. Neurosci. 18, 6113-6125
38. Silva, A. M., Liu-Gentry, J., Dickey, A. S., Barnett, D. W., and Misler, S. (2005) J. Physiol. (Lond.) 565, 783-799
39. Filippov, A. K., Tertishnikova, S. M., Alekseev, A. E., Tsurupa, G. P., Pashkov, V. N., and Grishin, E. V. (1994) Neuroscience 61, 179-189
40. Van Renterghem, C., Iborra, C., Martin-Moutot, N., Lelianova, V., Ushkaryov, Y., and Seagar, M. (2000) Eur. J. Neurosci. 12, 3953-3962
41. Hurlbut, W. P., Chieregatti, E., Valtorta, F., and Haimann, C. (1994) J. Membr. Biol. 138, 91-102
42. Wiser, O., Trus, M., Hernandez, A., Renstrom, E., Barg, S., Rorsman, P., and Atlas, D. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 248-253
43. Ichtchenko, K., Bittner, M. A., Krasnoperov, V., Little, A. R., Chepurny, O., Holz, R. W., and Petrenko, A. G. (1999) J. Biol. Chem. 274, 5491-5498
44. Grasso, A., Pelliccia, M., and Alema, S. (1982) Toxicon 20, 149-156
45. Terrillon, S., and Bouvier, M. (2004) EMBO Rep. 5, 30-34
46. Bourinet, E., Mangoni, M. E., and Nargeot, J. (2004) J. Clin. Invest. 113, 1382-1384
47. Weiss, S., Doan, T., Bernstein, K. E., and Dascal, N. (2004) J. Biol. Chem. 279, 12503-12510
48. Yang, L., Liu, G., Zakharov, S. I., Morrow, J. P., Rybin, V. O., Steinberg, S. F., and Marx, S. O. (2005) J. Biol. Chem. 280, 207-214
49. Dukes, I. D., and Philipson, L. H. (1996) Diabetes 45, 845-853
50. Henquin, J. C. (1990) Pflugers Arch. 416, 568-572
51. MacDonald, P. E., Wang, X., Xia, F., El-kholy, W., Targonsky, E. D., Tsushima, R. G., and Wheeler, M. B. (2003) J. Biol. Chem. 278, 52446-52453
52. MacDonald, P. E., Sewing, S., Wang, J., Joseph, J. W., Smukler, S. R., Sakellaropoulos, G., Saleh, M. C., Chan, C. B., Tsushima, R. G., Salapatek, A. M., and Wheeler, M. B. (2002) J. Biol. Chem. 277, 44938-44945
53. MacDonald, P. E., Ha, X. F., Wang, J., Smukler, S. R., Sun, A. M., Gaisano, H. Y., Salapatek, A. M., Backx, P. H., and Wheeler, M. B. (2001) Mol. Endocrinol. 15, 1423-1435
54. Eddlestone, G. T., Ribalet, B., and Ciani, S. (1989) J. Membr. Biol. 109, 123-134
55. Michelena, P., de la Fuente, M. T., Vega, T., Lara, B., Lopez, M. G., Gandia, L., and Garcia, A. G. (1997) J. Physiol. (Lond.) 502, 481-496
56. Willson, J., Amliwala, K., Davis, A., Cook, A., Cuttle, M. F., Kriek, N., Hopper, N. A., O'Connor, V., Harder, A., Walker, R. J., and Holden-Dye, L. (2004) Curr. Biol. 14, 1374-1379
57. Trimmer, J. S., and Rhodes, K. J. (2004) Annu. Rev. Physiol. 66, 477-519
58. Wang, Z. W., Saifee, O., Nonet, M. L., and Salkoff, L. (2001) Neuron 32, 867-881
59. Hu, H., Shao, L.-R., Chavoshy, S., Gu, N., Trieb, M., Behrens, R., Laake, P., Pongs, O., Knaus, H. G., Ottersen, O. P., and Storm, J. F. (2001) J. Neurosci. 21, 9585-9597
60. Tse, F. W., and Tse, A. (1999) Endocrinology 140, 3025-3033
61. Yang, Y., and Gillis, K. D. (2004) J. Gen. Physiol. 124, 641-651
62. Liu, J., Wan, Q., Lin, X., Zhu, H., Volynski, K., Ushkaryov, Y., and Xu, T. (2005) Traffic 6, 756-765