Constitutively active α subunits of Gq/11 and G 12/13 families inhibit activation of the pro-survival Akt signaling cascade

FEBS Journal

Volumn 273, Issue 11, 2006, Pages 2388-2398

  Wu, Eddy H T ^a   Tam, Becky H L ^a   Wong, Yung H ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

Akt; Cell survival; G protein; Growth factor; Tuberin

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; CALCIUM CHELATING AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN KINASE B; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TUBERIN;

ANTIBODY SPECIFICITY; ARTICLE; CALCIUM SIGNALING; CELL SURVIVAL; ENZYME ACTIVATION; ENZYME SUBUNIT; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MAMMAL CELL; MULTIGENE FAMILY; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; TRANSLATION REGULATION; WESTERN BLOTTING;

CELL LINE; CELL SURVIVAL; CYCLIC AMP; ENZYME ACTIVATION; ENZYME INHIBITORS; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HUMANS; KIDNEY; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TRANSFECTION;

MAMMALIA;

EID: 33646710125     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2006.05245.x     Document Type: Article

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