Akt activation induced by lysophosphatidic acid and sphingosine-1-phosphate requires both mitogen-activated protein kinase kinase and p38 mitogen-activated protein kinase and is cell-line specific

Molecular Pharmacology

Volumn 62, Issue 3, 2002, Pages 660-671

  Baudhuin, Linnea M ^a,b   Cristina, Kelly L ^a   Lu, Jun ^a   Xu, Yan ^a,b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CLEVELAND STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CASPASE 3; ENDOTHELIN 1; EPIDERMAL GROWTH FACTOR; INSULIN; LYSOPHOSPHATIDIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PACLITAXEL; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PROTEIN KINASE B; RHO FACTOR; SPHINGOSINE 1 PHOSPHATE; SYNAPTOPHYSIN; THROMBIN; WORTMANNIN;

ARTICLE; CANCER CELL CULTURE; CELL LINE; CELL SPECIFICITY; CELL SURVIVAL; CELL TYPE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; OVARY CANCER; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACUTE-PHASE PROTEINS; CASPASE 3; CASPASES; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIN-1; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HELA CELLS; HUMANS; INSULIN; LYSOPHOSPHOLIPIDS; MAP KINASE KINASE KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PACLITAXEL; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SPHINGOSINE; THROMBIN; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0036765743     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.62.3.660     Document Type: Article

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