메뉴 건너뛰기




Volumn 7, Issue 3, 2005, Pages

Regulation of monoamine transporters: Influence of psychostimulants and therapeutic antidepressants

Author keywords

Interacting proteins; Ligands; Phosphorylation; Substrates; Trafficking

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; 4 AMINOBUTYRIC ACID; AMINE; AMPHETAMINE; ANTIDEPRESSANT AGENT; CARRIER PROTEIN; CITALOPRAM; COCAINE; DOPAMINE; DOPAMINE TRANSPORTER; FLUOXETINE; IMIPRAMINE; ION CHANNEL; METHYLPHENIDATE; MONOAMINE; NEUROTOXIN; NEUROTRANSMITTER; NORADRENALIN; NORADRENALIN TRANSPORTER; PAROXETINE; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE; PSYCHOSTIMULANT AGENT; SECRETORY PROTEIN; SEROTONIN; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; SYNAPSE RECEPTOR; TRICYCLIC ANTIDEPRESSANT AGENT; UNINDEXED DRUG; CENTRAL STIMULANT AGENT; VESICULAR MONOAMINE TRANSPORTER;

EID: 33646649339     PISSN: 15221059     EISSN: 15221059     Source Type: Journal    
DOI: 10.1208/aapsj070373     Document Type: Review
Times cited : (108)

References (122)
  • 1
    • 0035044801 scopus 로고    scopus 로고
    • Serotonergic dysfunction, negative mood states, and response to alcohol
    • Heinz A, Mann K, Weinberger DR, Goldman D. Serotonergic dysfunction, negative mood states, and response to alcohol. Alcohol Clin Exp Res. 2001;25:487-495.
    • (2001) Alcohol Clin. Exp. Res. , vol.25 , pp. 487-495
    • Heinz, A.1    Mann, K.2    Weinberger, D.R.3    Goldman, D.4
  • 2
    • 0036046157 scopus 로고    scopus 로고
    • Monoamine transporter gene structure and polymorphisms in relation to psychiatric and other complex disorders
    • Hahn MK, Blakely RD, Monoamine transporter gene structure and polymorphisms in relation to psychiatric and other complex disorders. Pharmacogenomics J. 2002;2:217-235.
    • (2002) Pharmacogenomics J. , vol.2 , pp. 217-235
    • Hahn, M.K.1    Blakely, R.D.2
  • 3
    • 0032082917 scopus 로고    scopus 로고
    • Cocaine self-administration in dopamine-transporter knockout mice
    • Rocha BA, Fumagalli F, Gainetdinov RR, et al. Cocaine self-administration in dopamine-transporter knockout mice, Nat Neurosci. 1998;1:132-137.
    • (1998) Nat. Neurosci. , vol.1 , pp. 132-137
    • Rocha, B.A.1    Fumagalli, F.2    Gainetdinov, R.R.3
  • 4
    • 0035942241 scopus 로고    scopus 로고
    • Molecular mechanisms of cocaine reward: Combined dopamine and serotonin transporter knockouts eliminate cocaine place preference
    • Sora I, Hall FS, Andrews AM, et al. Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference. Proc Natl Acad Sci USA. 2001;98:5300-5305.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 5300-5305
    • Sora, I.1    Hall, F.S.2    Andrews, A.M.3
  • 5
    • 0033952855 scopus 로고    scopus 로고
    • Modified structure of the human serotonin transporter promoter
    • Flattem NL, Blakely RD. Modified structure of the human serotonin transporter promoter. Mol Psychiatry. 2000;5:110-115.
    • (2000) Mol. Psychiatry , vol.5 , pp. 110-115
    • Flattem, N.L.1    Blakely, R.D.2
  • 6
    • 2142645125 scopus 로고    scopus 로고
    • Linkage and association analysis at the serotonin transporter (SLC6A4) locus in a rigid-compulsive subset of autism
    • McCauley JL, Olson LM, Dowd M, et al. Linkage and association analysis at the serotonin transporter (SLC6A4) locus in a rigid-compulsive subset of autism. Am J Med Genet B Neuropsychiatr Genet. 2004;127:104-112.
    • (2004) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.127 , pp. 104-112
    • McCauley, J.L.1    Olson, L.M.2    Dowd, M.3
  • 7
    • 0242637392 scopus 로고    scopus 로고
    • Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype
    • Ozaki N, Goldman D, Kaye WH, et al. Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype. Mol Psychiatry. 2003;8:895-936.
    • (2003) Mol. Psychiatry , vol.8 , pp. 895-936
    • Ozaki, N.1    Goldman, D.2    Kaye, W.H.3
  • 8
    • 0042343721 scopus 로고    scopus 로고
    • A human serotonin transporter mutation causes constitutive activation of transport activity
    • Kilic F, Murphy DL, Rudnick G. A human serotonin transporter mutation causes constitutive activation of transport activity. Mol Pharmacol. 2003;64:440-446.
    • (2003) Mol. Pharmacol. , vol.64 , pp. 440-446
    • Kilic, F.1    Murphy, D.L.2    Rudnick, G.3
  • 9
    • 0025076980 scopus 로고
    • Anatomical evidence for multiple pathways leading from the rostral ventrolateral medulla (nucleus paragigantocellularis) to the locus coeruleus in rat
    • Astier B, Van Bockstaele EJ, Aston-Jones G, Pieribone VA. Anatomical evidence for multiple pathways leading from the rostral ventrolateral medulla (nucleus paragigantocellularis) to the locus coeruleus in rat. Neurosci Lett. 1990;118:141-146.
    • (1990) Neurosci. Lett. , vol.118 , pp. 141-146
    • Astier, B.1    Van Bockstaele, E.J.2    Aston-Jones, G.3    Pieribone, V.A.4
  • 11
    • 0035903051 scopus 로고    scopus 로고
    • Microinjection of carbachol in the lateral hypothalamus produces opposing actions on nociception mediated by alpha(1)- and alpha(2)-adrenoceptors
    • Holden JE, Naleway E. Microinjection of carbachol in the lateral hypothalamus produces opposing actions on nociception mediated by alpha(1)- and alpha(2)-adrenoceptors. Brain Res. 2001;911:27-36.
    • (2001) Brain Res. , vol.911 , pp. 27-36
    • Holden, J.E.1    Naleway, E.2
  • 12
    • 0037154162 scopus 로고    scopus 로고
    • The NK1 receptor mediates both the hyperalgesia and the resistance to morphine in mice lacking noradrenaline
    • Jasmin L, Tien D, Weinshenker D. The NK1 receptor mediates both the hyperalgesia and the resistance to morphine in mice lacking noradrenaline. Proc Natl Acad Sci USA. 2002;99:1029-1034.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 1029-1034
    • Jasmin, L.1    Tien, D.2    Weinshenker, D.3
  • 13
    • 0014453248 scopus 로고
    • The uptake, storage, releas and metabolism of noradrenaline in sympathetice nerves
    • Axelrod J, Kopin IJ. The uptake, storage, releas and metabolism of noradrenaline in sympathetice nerves. Prog Brain Res. 1969;31:21-32.
    • (1969) Prog. Brain Res. , vol.31 , pp. 21-32
    • Axelrod, J.1    Kopin, I.J.2
  • 14
    • 0001959399 scopus 로고
    • Uptake processes for biogenic amines
    • Iversen I, ed. 3rd ed. New York, NY: Prenum Press
    • Iversen LL. Uptake processes for biogenic amines. In: Iversen I, ed. Handbook of Psychopharmacology. 3rd ed. New York, NY: Prenum Press; 1978:381-442.
    • (1978) Handbook of Psychopharmacology , pp. 381-442
    • Iversen, L.L.1
  • 15
    • 0026433037 scopus 로고
    • Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter
    • Pacholczyk T, Blakely RD, Amara SG, Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter. Nature. 1991;350:350-354.
    • (1991) Nature , vol.350 , pp. 350-354
    • Pacholczyk, T.1    Blakely, R.D.2    Amara, S.G.3
  • 16
    • 0027240164 scopus 로고
    • Neurotransmitter transporters: Three distinct gene families
    • Amara SG, Arriza JL. Neurotransmitter transporters: three distinct gene families. Curr Opin Neurobiol. 1993;3:337-344.
    • (1993) Curr. Opin. Neurobiol. , vol.3 , pp. 337-344
    • Amara, S.G.1    Arriza, J.L.2
  • 17
    • 16944362115 scopus 로고    scopus 로고
    • Reduced levels of norepinephrine transporters in the locus coeruleus in major depression
    • Klimek V, Stockmeier C, Overholser J, et al. Reduced levels of norepinephrine transporters in the locus coeruleus in major depression. J Neurosci. 1997;17:8451-8458.
    • (1997) J. Neurosci. , vol.17 , pp. 8451-8458
    • Klimek, V.1    Stockmeier, C.2    Overholser, J.3
  • 19
    • 0026530512 scopus 로고
    • Myocardial b-adrenergic desensitization and neuronal norepinephrine uptake function in idiopathic dilated cardiomyopathy
    • Merlet P, Dubois-Rande J-L, Adnot S, et al. Myocardial b-adrenergic desensitization and neuronal norepinephrine uptake function in idiopathic dilated cardiomyopathy. J Cardiovasc Pharmacol. 1992;19:10-16.
    • (1992) J. Cardiovasc. Pharmacol. , vol.19 , pp. 10-16
    • Merlet, P.1    Dubois-Rande, J.-L.2    Adnot, S.3
  • 20
    • 0034937901 scopus 로고    scopus 로고
    • Familial orthostatic tachycardia due to norepinephrine transporter deficiency
    • Robertson D, Flattem N, Tellioglu T, et al. Familial orthostatic tachycardia due to norepinephrine transporter deficiency. Ann N Y Acad Sci. 2001;940:527-543.
    • (2001) Ann. N. Y. Acad. Sci. , vol.940 , pp. 527-543
    • Robertson, D.1    Flattem, N.2    Tellioglu, T.3
  • 21
    • 0033915420 scopus 로고    scopus 로고
    • Mice lacking the norepinephrine transporter are supersensitive to psychostimulants
    • Xu F, Gainetdinov RR, Wetsel WC, et al. Mice lacking the norepinephrine transporter are supersensitive to psychostimulants. Nat Neurosci. 2000;3:465-471
    • (2000) Nat. Neurosci. , vol.3 , pp. 465-471
    • Xu, F.1    Gainetdinov, R.R.2    Wetsel, W.C.3
  • 22
    • 0034671384 scopus 로고    scopus 로고
    • Kappa-opioid receptor activation modifies dopamine uptake in the nucleus accumbens and opposes the effects of cocaine
    • Thompson AC, Zapata A, Justice JB, Vaughan RA, Sharpe LG, Shippenberg TS. Kappa-opioid receptor activation modifies dopamine uptake in the nucleus accumbens and opposes the effects of cocaine. J Neurosci. 2000;20:9333-9340.
    • (2000) J. Neurosci. , vol.20 , pp. 9333-9340
    • Thompson, A.C.1    Zapata, A.2    Justice, J.B.3    Vaughan, R.A.4    Sharpe, L.G.5    Shippenberg, T.S.6
  • 23
    • 0038118243 scopus 로고    scopus 로고
    • A mutation in the human norepinephrine transporter gene (SLC6A2) associated with orthostatic intolerance disrupts surface expression of mutant and wild-type transporters
    • Hahn MK, Robertson D, Blakely RD. A mutation in the human norepinephrine transporter gene (SLC6A2) associated with orthostatic intolerance disrupts surface expression of mutant and wild-type transporters. J Neurosci. 2003;23:4470-4478.
    • (2003) J. Neurosci. , vol.23 , pp. 4470-4478
    • Hahn, M.K.1    Robertson, D.2    Blakely, R.D.3
  • 25
    • 0035798093 scopus 로고    scopus 로고
    • The neurobiology of slow synaptic transmission
    • Greengard P. The neurobiology of slow synaptic transmission. Science. 2001;294:1024-1030.
    • (2001) Science , vol.294 , pp. 1024-1030
    • Greengard, P.1
  • 26
    • 0029032794 scopus 로고
    • Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport
    • Sulzer D, Chen TK, Lau YY, Kristensen H, Rayport S, Ewing A. Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport. J Neurosci. 1995;15:4102-4108.
    • (1995) J. Neurosci. , vol.15 , pp. 4102-4108
    • Sulzer, D.1    Chen, T.K.2    Lau, Y.Y.3    Kristensen, H.4    Rayport, S.5    Ewing, A.6
  • 27
    • 0032560560 scopus 로고    scopus 로고
    • Cocaine reward models: Conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice
    • Sora I, Wichems C, Takahashi N, et al. Cocaine reward models: conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice. Proc Natl Acad Sci USA, 1998;95:7699-7704.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 7699-7704
    • Sora, I.1    Wichems, C.2    Takahashi, N.3
  • 28
    • 0033525562 scopus 로고    scopus 로고
    • Adaptive changes of serotonin 5-HT2A receptors in mice lacking the serotonin transporter
    • Rioux A, Fabre V, Lesch KP, et al. Adaptive changes of serotonin 5-HT2A receptors in mice lacking the serotonin transporter. Neurosci Lett. 1999;262:113-116.
    • (1999) Neurosci. Lett. , vol.262 , pp. 113-116
    • Rioux, A.1    Fabre, V.2    Lesch, K.P.3
  • 29
    • 0035347177 scopus 로고    scopus 로고
    • Cocaine and amphetamine increase extracellular dopamine in the nucleus accumbens of mice lacking the dopamine transporter gene
    • Carboni E, Spielewoy C, Vacca C, Nosten-Bertrand M, Giros B, Di Chiara G. Cocaine and amphetamine increase extracellular dopamine in the nucleus accumbens of mice lacking the dopamine transporter gene. J Neurosci. 2001;21:1-4.
    • (2001) J. Neurosci. , vol.21 , pp. 1-4
    • Carboni, E.1    Spielewoy, C.2    Vacca, C.3    Nosten-Bertrand, M.4    Giros, B.5    Di Chiara, G.6
  • 30
    • 0025961215 scopus 로고
    • Lack of increase in dopamine transporter binding or functions in rat brain tissue after treatment with blockers of neuronal uptake of dopamine
    • Kula NS, Baldessarini RJ, Lack of increase in dopamine transporter binding or functions in rat brain tissue after treatment with blockers of neuronal uptake of dopamine. Neuropharmacology. 1991;30:89-92.
    • (1991) Neuropharmacology , vol.30 , pp. 89-92
    • Kula, N.S.1    Baldessarini, R.J.2
  • 31
    • 0027049060 scopus 로고
    • Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter
    • Giros B, El Mestikawy S, Godinot N, et al. Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter. Mol Pharmacol. 1992;42:383-390.
    • (1992) Mol. Pharmacol. , vol.42 , pp. 383-390
    • Giros, B.1    El Mestikawy, S.2    Godinot, N.3
  • 32
    • 0030071106 scopus 로고    scopus 로고
    • Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
    • Giros B, Jaber M, Jones SR, Wightman RM, Caron MG. Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature. 1996;379:606-612.
    • (1996) Nature , vol.379 , pp. 606-612
    • Giros, B.1    Jaber, M.2    Jones, S.R.3    Wightman, R.M.4    Caron, M.G.5
  • 33
    • 0025343642 scopus 로고
    • Neurochemical and psychopharmacologic aspects of aggressive behavior
    • Eichelman BS. Neurochemical and psychopharmacologic aspects of aggressive behavior. Annu Rev Med. 1990;41:149-158.
    • (1990) Annu. Rev. Med. , vol.41 , pp. 149-158
    • Eichelman, B.S.1
  • 34
    • 0034952023 scopus 로고    scopus 로고
    • Clinical and molecular genetics of ADHD and Tourette syndrome: Two related polygenic disorders
    • Comings DE. Clinical and molecular genetics of ADHD and Tourette syndrome: two related polygenic disorders. Ann N Y Acad Sci. 2001;931:50-83.
    • (2001) Ann. N. Y. Acad. Sci. , vol.931 , pp. 50-83
    • Comings, D.E.1
  • 36
    • 0035139190 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms distinguish multiple dopamine transporter alleles in primates: Implications for association with attention deficit hyperactivity disorder and other neuropsychiatric disorders
    • Miller GM, II, De La Garza RD, II, Novak MA, Madras BK. Single nucleotide polymorphisms distinguish multiple dopamine transporter alleles in primates: implications for association with attention deficit hyperactivity disorder and other neuropsychiatric disorders. Mol Psychiatry. 2001;6:50-58.
    • (2001) Mol. Psychiatry , vol.6 , pp. 50-58
    • Miller II, G.M.1    De La Garza II, R.D.2    Novak, M.A.3    Madras, B.K.4
  • 37
    • 0036211072 scopus 로고    scopus 로고
    • Dopamine transporter mutants with cocaine resistance and normal dopamine uptake provide targets for cocaine antagonism
    • Lin Z, Uhl GR. Dopamine transporter mutants with cocaine resistance and normal dopamine uptake provide targets for cocaine antagonism. Mol Pharmacol. 2002;61:885-891.
    • (2002) Mol. Pharmacol. , vol.61 , pp. 885-891
    • Lin, Z.1    Uhl, G.R.2
  • 38
    • 0022481325 scopus 로고
    • Structural requirements for cocaine congeners to interact with dopamine and serotonin uptake sites in mouse brain and to induce stereotyped behavior
    • Reith MEA, Meisler BE, Sershen H, Lajtha A. Structural requirements for cocaine congeners to interact with dopamine and serotonin uptake sites in mouse brain and to induce stereotyped behavior. Biochem Pharmacol. 1986;35:1123-1129.
    • (1986) Biochem. Pharmacol. , vol.35 , pp. 1123-1129
    • Reith, M.E.A.1    Meisler, B.E.2    Sershen, H.3    Lajtha, A.4
  • 40
    • 0031978809 scopus 로고    scopus 로고
    • Altered brain serotonin homeostasis and locomotor insensitivity to 3,4-methylenedioxymetamphetamine ("ecstacy") in sertonin transporter-deficient mice
    • Bengel D, Murphy DL, Andrews AM, et al. Altered brain serotonin homeostasis and locomotor insensitivity to 3,4-methylenedioxymetamphetamine ("ecstacy") in serotonin transporter-deficient mice. Mol. Pharmacol. 1998;53:649-655.
    • (1998) Mol. Pharmacol. , vol.53 , pp. 649-655
    • Bengel, D.1    Murphy, D.L.2    Andrews, A.M.3
  • 41
    • 0032516173 scopus 로고    scopus 로고
    • Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor
    • Rocha BA, Scearce-Levie K, Lucas JJ, et al. Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor. Nature. 1998;393:175-178.
    • (1998) Nature , vol.393 , pp. 175-178
    • Rocha, B.A.1    Scearce-Levie, K.2    Lucas, J.J.3
  • 42
    • 0030766528 scopus 로고    scopus 로고
    • Molecular and cellular basis of addiction
    • Nestler EJ, Aghajanian GK. Molecular and cellular basis of addiction. Science. 1997;278:58-63.
    • (1997) Science , vol.278 , pp. 58-63
    • Nestler, E.J.1    Aghajanian, G.K.2
  • 43
    • 16944366966 scopus 로고    scopus 로고
    • Repeated cocaine modifies the mechanism by which amphetamine releases dopamine
    • Pierce RC, Kalivas PW. Repeated cocaine modifies the mechanism by which amphetamine releases dopamine. J Neurosci. 1997;17:3254-3261.
    • (1997) J. Neurosci. , vol.17 , pp. 3254-3261
    • Pierce, R.C.1    Kalivas, P.W.2
  • 44
    • 0032171588 scopus 로고    scopus 로고
    • Plasma membrane transporters of serotonin, dopamine, and norepinephrine mediate serotonin accumulation in atypical locations in the developing brain of monoamine oxidase A knock-outs
    • Cases O, Lebrand C, Giros B, et al. Plasma membrane transporters of serotonin, dopamine, and norepinephrine mediate serotonin accumulation in atypical locations in the developing brain of monoamine oxidase A knock-outs. J Neurosci. 1998;18:6914-6927.
    • (1998) J. Neurosci. , vol.18 , pp. 6914-6927
    • Cases, O.1    Lebrand, C.2    Giros, B.3
  • 45
    • 0035977577 scopus 로고    scopus 로고
    • Plasticity in serotonin uptake in primary neuronal cultures of serotonin transporter knockout mice
    • Pan Y, Gembom E, Peng W, Lesch KP, Mossner R, Simantov R. Plasticity in serotonin uptake in primary neuronal cultures of serotonin transporter knockout mice. Brain Res Dev Brain Res. 2001;126:125-129.
    • (2001) Brain Res. Dev. Brain Res. , vol.126 , pp. 125-129
    • Pan, Y.1    Gembom, E.2    Peng, W.3    Lesch, K.P.4    Mossner, R.5    Simantov, R.6
  • 46
    • 0037080158 scopus 로고    scopus 로고
    • Dopamine uptake through the norepinephrine transporter in brain regions with low levels of the dopamine transporter: Evidence from knock-out mouse lines
    • Moron JA, Brockington A, Wise RA, Rocha BA, Hope BT. Dopamine uptake through the norepinephrine transporter in brain regions with low levels of the dopamine transporter: evidence from knock-out mouse lines. J Neurosci. 2002;22:389-395.
    • (2002) J. Neurosci. , vol.22 , pp. 389-395
    • Moron, J.A.1    Brockington, A.2    Wise, R.A.3    Rocha, B.A.4    Hope, B.T.5
  • 47
    • 0027364837 scopus 로고
    • Regulation of the human serotonin transporter: Cholera toxin-induced stimulation of serotonin uptake in human placental choriocarcinoma cells is accompanied by increased serotonin transporter mRNA levels and serotonin transporter-specific ligand binding
    • Ramamoorthy S, Cool DR, Mahesh VB, et al. Regulation of the human serotonin transporter: cholera toxin-induced stimulation of serotonin uptake in human placental choriocarcinoma cells is accompanied by increased serotonin transporter mRNA levels and serotonin transporter-specific ligand binding. J Biol Chem. 1993;268:21626-21631.
    • (1993) J. Biol. Chem. , vol.268 , pp. 21626-21631
    • Ramamoorthy, S.1    Cool, D.R.2    Mahesh, V.B.3
  • 53
    • 0029884778 scopus 로고    scopus 로고
    • Noradrenaline transport and transporter mRNA of rat chromaffin cells are controlled by dexamethasone and nerve growth factor
    • Wakade AR, Wakade TD, Poosch M, Bannon MJ. Noradrenaline transport and transporter mRNA of rat chromaffin cells are controlled by dexamethasone and nerve growth factor. J Physiol. 1996;494:67-75.
    • (1996) J. Physiol. , vol.494 , pp. 67-75
    • Wakade, A.R.1    Wakade, T.D.2    Poosch, M.3    Bannon, M.J.4
  • 54
    • 0027400795 scopus 로고
    • Insulin reduces norepinephrine transporter mRNA in vivo in rat locus coeruleus
    • Figlewicz DP, Szot P, Israel PA, Payne C, Dorsa DM. Insulin reduces norepinephrine transporter mRNA in vivo in rat locus coeruleus. Brain Res. 1993;602:161-164.
    • (1993) Brain Res. , vol.602 , pp. 161-164
    • Figlewicz, D.P.1    Szot, P.2    Israel, P.A.3    Payne, C.4    Dorsa, D.M.5
  • 55
    • 0030460121 scopus 로고    scopus 로고
    • Monoamine transporters and the neurobehavioral teratology of cocaine
    • Meyer JS, Shearman LP, Collins LM. Monoamine transporters and the neurobehavioral teratology of cocaine. Pharmacol Biochem Behav. 1996;55:585-593.
    • (1996) Pharmacol. Biochem. Behav. , vol.55 , pp. 585-593
    • Meyer, J.S.1    Shearman, L.P.2    Collins, L.M.3
  • 56
    • 0035977697 scopus 로고    scopus 로고
    • Nerve growth factor down-regulates the expression of norepinephrine transporter in rat pheochromocytoma (PC12) cells
    • Ikeda T, Kitayama S, Morita K, Dohi T. Nerve growth factor down-regulates the expression of norepinephrine transporter in rat pheochromocytoma (PC12) cells. Brain Res Mol Brain Res. 2001;86:90-100.
    • (2001) Brain Res. Mol. Brain Res. , vol.86 , pp. 90-100
    • Ikeda, T.1    Kitayama, S.2    Morita, K.3    Dohi, T.4
  • 57
    • 0033570335 scopus 로고    scopus 로고
    • Cocaine upregulates the dopamine transporter in fetal rhesus monkey brain
    • Fang Y, Ronnekleiv OK. Cocaine upregulates the dopamine transporter in fetal rhesus monkey brain. J Neurosci. 1999;19:8966-8978.
    • (1999) J. Neurosci. , vol.19 , pp. 8966-8978
    • Fang, Y.1    Ronnekleiv, O.K.2
  • 58
    • 0033432876 scopus 로고    scopus 로고
    • Cocaine up-regulates norepinephrine transporter binding in the rat placenta
    • Shearman LP, Meyer JS. Cocaine up-regulates norepinephrine transporter binding in the rat placenta. Eur J Pharmacol. 1999;386:1-6.
    • (1999) Eur J. Pharmacol. , vol.386 , pp. 1-6
    • Shearman, L.P.1    Meyer, J.S.2
  • 59
    • 0037220932 scopus 로고    scopus 로고
    • Chronic cocaine self-administration upregulates the norepinephrine transporter and alters functional activity in the bed nucleus of the stria terminalis of the rhesus monkey
    • Macey DJ, Smith HR, Nader MA, Porrino LJ. Chronic cocaine self-administration upregulates the norepinephrine transporter and alters functional activity in the bed nucleus of the stria terminalis of the rhesus monkey. J Neurosci. 2003;23:12-16.
    • (2003) J. Neurosci. , vol.23 , pp. 12-16
    • Macey, D.J.1    Smith, H.R.2    Nader, M.A.3    Porrino, L.J.4
  • 60
    • 2442637536 scopus 로고    scopus 로고
    • The role of N-glycosylation in function and surface trafficking of the human dopamine transporter
    • Li LB, Chen N, Ramamoorthy S, et al. The role of N-glycosylation in function and surface trafficking of the human dopamine transporter. J Biol Chem. 2004;279:21012-21020.
    • (2004) J. Biol. Chem. , vol.279 , pp. 21012-21020
    • Li, L.B.1    Chen, N.2    Ramamoorthy, S.3
  • 61
    • 0030972751 scopus 로고    scopus 로고
    • Protein kinase C-mediated phosphorylation and functional regulation of dopamine transporters in striatal synaptosomes
    • Vaughan RA, Huff RA, Uhl GR, Kuhar MJ. Protein kinase C-mediated phosphorylation and functional regulation of dopamine transporters in striatal synaptosomes. J Biol Chem. 1997;272:15541-15546.
    • (1997) J. Biol. Chem. , vol.272 , pp. 15541-15546
    • Vaughan, R.A.1    Huff, R.A.2    Uhl, G.R.3    Kuhar, M.J.4
  • 62
    • 0031915461 scopus 로고    scopus 로고
    • Phosphorylation and regulation of antidepressant-sensitive serotonin transporters
    • Ramamoorthy S, Giovanetti E, Qian Y, Blakely RD. Phosphorylation and regulation of antidepressant-sensitive serotonin transporters. J Biol Chem. 1998;273:2458-2466.
    • (1998) J. Biol. Chem. , vol.273 , pp. 2458-2466
    • Ramamoorthy, S.1    Giovanetti, E.2    Qian, Y.3    Blakely, R.D.4
  • 63
    • 2442444165 scopus 로고    scopus 로고
    • Regulated internalization and phosphorylation of the native norepinephrine transporter in response to phorbol esters: Evidence for localization in lipid rafts and lipid raft mediated internalization
    • Jayanthi LD, Samuvel DJ, Ramamoorthy S. Regulated internalization and phosphorylation of the native norepinephrine transporter in response to phorbol esters: evidence for localization in lipid rafts and lipid raft mediated internalization. J Biol Chem. 2004;279:19315-19326.
    • (2004) J. Biol. Chem. , vol.279 , pp. 19315-19326
    • Jayanthi, L.D.1    Samuvel, D.J.2    Ramamoorthy, S.3
  • 64
    • 0032465989 scopus 로고    scopus 로고
    • Acute regulation of norepinephrine transport. I. PKC-linked muscarinic receptors influence transport capacity and transporter density in SK-N-SH cells
    • Apparsundaram S, Galli A, DeFelice LJ, Hartzell HC, Blakely RD. Acute regulation of norepinephrine transport. I. PKC-linked muscarinic receptors influence transport capacity and transporter density in SK-N-SH cells. J Pharmacol Exp Ther. 1998;287:733-743.
    • (1998) J. Pharmacol. Exp. Ther. , vol.287 , pp. 733-743
    • Apparsundaram, S.1    Galli, A.2    DeFelice, L.J.3    Hartzell, H.C.4    Blakely, R.D.5
  • 65
    • 0032456140 scopus 로고    scopus 로고
    • Acute modulated of norepinephrine transport. II. PKC-modulated surface expression of human norepinephrine transporter proteins
    • Apparsundaram S, Schroeter S, Blakely RD. Acute modulated of norepinephrine transport. II. PKC-modulated surface expression of human norepinephrine transporter proteins. J Pharmacol Exp Ther. 1998;287:744-751.
    • (1998) J. Pharmacol. Exp. Ther. , vol.287 , pp. 744-751
    • Apparsundaram, S.1    Schroeter, S.2    Blakely, R.D.3
  • 66
    • 0034667557 scopus 로고    scopus 로고
    • Cocaine and antidepressant-sensitive biogenic amine transporters exist in regulated complexes with protein phosphatase 2A
    • Bauman AL, Apparsundaram S, Ramamoorthy S, Wadzinski BE, Vaughan RA, Blakely RD. Cocaine and antidepressant-sensitive biogenic amine transporters exist in regulated complexes with protein phosphatase 2A. J Neurosci. 2000;20:7571-7578.
    • (2000) J. Neurosci. , vol.20 , pp. 7571-7578
    • Bauman, A.L.1    Apparsundaram, S.2    Ramamoorthy, S.3    Wadzinski, B.E.4    Vaughan, R.A.5    Blakely, R.D.6
  • 67
    • 0031014266 scopus 로고    scopus 로고
    • Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression
    • Qian Y, Galli A, Ramamoorthy S, Risso S, DeFelice LJ, Blakely RD. Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression. J Neurosci. 1997;17:45-57.
    • (1997) J. Neurosci. , vol.17 , pp. 45-57
    • Qian, Y.1    Galli, A.2    Ramamoorthy, S.3    Risso, S.4    DeFelice, L.J.5    Blakely, R.D.6
  • 68
    • 0028169067 scopus 로고
    • Phorbol esters alter functions of the expressed dopamine transporter
    • Kitayama S, Dohi T, Uhl G. Phorbol esters alter functions of the expressed dopamine transporter. Eur J Pharmacol. 1994;268:115-119.
    • (1994) Eur. J. Pharmacol. , vol.268 , pp. 115-119
    • Kitayama, S.1    Dohi, T.2    Uhl, G.3
  • 69
    • 0030936222 scopus 로고    scopus 로고
    • Regulation of the functional activity of the human dopamine transporter by protein kinase C
    • Zhang L, Coffey LL, Reith MEA. Regulation of the functional activity of the human dopamine transporter by protein kinase C. Biochem Pharmacol. 1997;53:677-688.
    • (1997) Biochem. Pharmacol. , vol.53 , pp. 677-688
    • Zhang, L.1    Coffey, L.L.2    Reith, M.E.A.3
  • 70
    • 0033544844 scopus 로고    scopus 로고
    • Regulation trafficking of the human dopamine transporter clathrin-mediated internalization and lysosomal degradation in response to phorbol esters
    • Daniels G, Amara SG. Regulation trafficking of the human dopamine transporter clathrin-mediated internalization and lysosomal degradation in response to phorbol esters. J Biol Chem. 1999;274:35794-35801.
    • (1999) J. Biol. Chem. , vol.274 , pp. 35794-35801
    • Daniels, G.1    Amara, S.G.2
  • 71
    • 0033568870 scopus 로고    scopus 로고
    • Membrane trafficking regulates the activity of the human dopamine transporter
    • Melikian HE. Bucklev KM. Membrane trafficking regulates the activity of the human dopamine transporter. J Neurosci. 1999;19:7699-7710.
    • (1999) J. Neurosci. , vol.19 , pp. 7699-7710
    • Melikian, H.E.1    Bucklev, K.M.2
  • 72
    • 0037820586 scopus 로고    scopus 로고
    • The dopamine transporter constitutively internalizes and recycles in a protein kinase C-regulated manner in stably transfected PC12 cell lines
    • Loder MK, Melikian HE. The dopamine transporter constitutively internalizes and recycles in a protein kinase C-regulated manner in stably transfected PC12 cell lines. J Biol Chem. 2003;278:22168-22174.
    • (2003) J. Biol. Chem. , vol.278 , pp. 22168-22174
    • Loder, M.K.1    Melikian, H.E.2
  • 73
    • 12744281091 scopus 로고    scopus 로고
    • Constitutive and protein kinase C-induced internalization of the dopamine transporter is mediated by a clathrin-dependent mechanism
    • Sorkina T, Hoover BR, Zahniser NR, Sorkin A. Constitutive and protein kinase C-induced internalization of the dopamine transporter is mediated by a clathrin-dependent mechanism. Traffic. 2005;6:157-170.
    • (2005) Traffic , vol.6 , pp. 157-170
    • Sorkina, T.1    Hoover, B.R.2    Zahniser, N.R.3    Sorkin, A.4
  • 74
    • 24944439152 scopus 로고    scopus 로고
    • Nonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization
    • Holton KL, Loder MK, Melikian HE. Nonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization. Nat Neurosci. 2005;8:881-888.
    • (2005) Nat. Neurosci. , vol.8 , pp. 881-888
    • Holton, K.L.1    Loder, M.K.2    Melikian, H.E.3
  • 75
    • 12144279565 scopus 로고    scopus 로고
    • A role for p38 mitogen-activated protein kinase in the regulation of the serotonin transporter: Evidence for distinct cellular mechanisms involved in transporter surface expression
    • Samuvel DJ, Jayanthi LD, Bhat NR, Ramamoorthy S. A role for p38 mitogen-activated protein kinase in the regulation of the serotonin transporter: evidence for distinct cellular mechanisms involved in transporter surface expression. J Neurosci. 2005;25:29-41.
    • (2005) J. Neurosci. , vol.25 , pp. 29-41
    • Samuvel, D.J.1    Jayanthi, L.D.2    Bhat, N.R.3    Ramamoorthy, S.4
  • 78
    • 0027514875 scopus 로고
    • Sodium- and chloride-dependent, cocaine-sensitive, high-affinity binding of nisoxetine to the human placental norepinephrine transporter
    • Jayanthi LD, Prasad PD, Ramamoorthy S, Mahesh VB, Leibach FH, Ganapathy V. Sodium- and chloride-dependent, cocaine-sensitive, high-affinity binding of nisoxetine to the human placental norepinephrine transporter. Biochemistry. 1993;32:12178-12185.
    • (1993) Biochemistry , vol.32 , pp. 12178-12185
    • Jayanthi, L.D.1    Prasad, P.D.2    Ramamoorthy, S.3    Mahesh, V.B.4    Leibach, F.H.5    Ganapathy, V.6
  • 79
    • 0037147217 scopus 로고    scopus 로고
    • The vesicle-and target-SNARE proteins that mediate Glut4 vesicle fusion are localized in detergent-insoluble lipid rafts present on distinct intracellular membranes
    • Chamberlain LH, Gould GW. The vesicle-and target-SNARE proteins that mediate Glut4 vesicle fusion are localized in detergent-insoluble lipid rafts present on distinct intracellular membranes. J Biol Chem. 2002;277:49750-49754.
    • (2002) J. Biol. Chem. , vol.277 , pp. 49750-49754
    • Chamberlain, L.H.1    Gould, G.W.2
  • 81
    • 0030949124 scopus 로고    scopus 로고
    • Functional rafts in cell membranes
    • Simons K, Ikonen E. Functional rafts in cell membranes. Nature. 1997;387:569-572.
    • (1997) Nature , vol.387 , pp. 569-572
    • Simons, K.1    Ikonen, E.2
  • 82
    • 0242268532 scopus 로고    scopus 로고
    • Lipid rafts and caveolae as portals for edocytosis: New insights and common mechanisms
    • Parton RG, Richards AA. Lipid rafts and caveolae as portals for edocytosis: new insights and common mechanisms. Traffic. 2003;4:724-738.
    • (2003) Traffic , vol.4 , pp. 724-738
    • Parton, R.G.1    Richards, A.A.2
  • 83
    • 0034757985 scopus 로고    scopus 로고
    • Trafficking-dependent and -independent pathways of neurotransmitter transporter regulation differentially involving p38 mitogen-activated protein kinase revealed in studies of insulin modulation of norepinephrine transport in SK-N-SH cells
    • Apparsundaram S, Sung U, Price RD, Blakely RD. Trafficking-dependent and -independent pathways of neurotransmitter transporter regulation differentially involving p38 mitogen-activated protein kinase revealed in studies of insulin modulation of norepinephrine transport in SK-N-SH cells. J Pharmacol Exp Ther. 2001;299:666-677.
    • (2001) J. Pharmacol. Exp. Ther. , vol.299 , pp. 666-677
    • Apparsundaram, S.1    Sung, U.2    Price, R.D.3    Blakely, R.D.4
  • 84
    • 0036316735 scopus 로고    scopus 로고
    • Pl 3-kinase regulation of dopamine uptake
    • Carvelli L, Moron JA, Kahlig KM, et al. Pl 3-kinase regulation of dopamine uptake. J Neurochem. 2002;81:859-869.
    • (2002) J. Neurochem. , vol.81 , pp. 859-869
    • Carvelli, L.1    Moron, J.A.2    Kahlig, K.M.3
  • 85
    • 0141569571 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase regulates dopamine transporter surface expression and dopamine transport capacity
    • Moron JA, Zakharova I, Ferrer JV, et al. Mitogen-activated protein kinase regulates dopamine transporter surface expression and dopamine transport capacity. J Neurosci. 2003;23:8480-8488.
    • (2003) J. Neurosci. , vol.23 , pp. 8480-8488
    • Moron, J.A.1    Zakharova, I.2    Ferrer, J.V.3
  • 86
    • 2442650231 scopus 로고    scopus 로고
    • Adenosine receptor, protein kinase G, and p38 mitogen-activated protein kinase-dependent up-regulation of serotonin transporters involves both transporter trafficking and activation
    • Zhu CB, Hewlett WA, Feoktistov I, Biaggioni I, Blakely RD. Adenosine receptor, protein kinase G, and p38 mitogen-activated protein kinase-dependent up-regulation of serotonin transporters involves both transporter trafficking and activation. Mol Pharmacol. 2004;65:1462-1474.
    • (2004) Mol. Pharmacol. , vol.65 , pp. 1462-1474
    • Zhu, C.B.1    Hewlett, W.A.2    Feoktistov, I.3    Biaggioni, I.4    Blakely, R.D.5
  • 88
    • 0028172409 scopus 로고
    • 3 receptors regulate serotonin transport via nitric oxide and cGMP
    • 3 receptors regulate serotonin transport via nitric oxide and cGMP. J Biol Chem. 1994;269:27351-27356.
    • (1994) J. Biol. Chem. , vol.269 , pp. 27351-27356
    • Miller, K.J.1    Hoffman, B.J.2
  • 90
    • 0033618638 scopus 로고    scopus 로고
    • Phosphorylation and sequestration of serotonin transporters differentially modulated by psychostimulants
    • Ramamoorthy S, Blakely RD. Phosphorylation and sequestration of serotonin transporters differentially modulated by psychostimulants. Science. 1999;285:763-786.
    • (1999) Science , vol.285 , pp. 763-786
    • Ramamoorthy, S.1    Blakely, R.D.2
  • 91
    • 0037067690 scopus 로고    scopus 로고
    • Dopamine transporters are phosphorylated on N-terminal serines in rat striatum
    • Foster JD, Pananusorn B, Vaughan RA. Dopamine transporters are phosphorylated on N-terminal serines in rat striatum. J Biol Chem. 2002;277:25178-25186.
    • (2002) J. Biol. Chem. , vol.277 , pp. 25178-25186
    • Foster, J.D.1    Pananusorn, B.2    Vaughan, R.A.3
  • 92
    • 0003189160 scopus 로고    scopus 로고
    • Role of protein kinase C and second messengers in regulation of the norepinephrine transporter
    • Bonisch H, Hammermann R, Bruss M. Role of protein kinase C and second messengers in regulation of the norepinephrine transporter. Adv Pharmacol. 1998;42:183-186.
    • (1998) Adv. Pharmacol. , vol.42 , pp. 183-186
    • Bonisch, H.1    Hammermann, R.2    Bruss, M.3
  • 93
    • 0035210307 scopus 로고    scopus 로고
    • Upregulation of gamma-aminobutyric acid transporter expression: Role of alkylated gamma-aminobutyric acid derivatives
    • Whitworth TL, Quick MW. Upregulation of gamma-aminobutyric acid transporter expression: role of alkylated gamma-aminobutyric acid derivatives. Biochem Soc Trans. 2001;29:736-741.
    • (2001) Biochem. Soc. Trans. , vol.29 , pp. 736-741
    • Whitworth, T.L.1    Quick, M.W.2
  • 94
    • 0037775994 scopus 로고    scopus 로고
    • N-terminl truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-simulated phosphorylation without impairing transporter internalization
    • Granas C, Ferrer J, Loland CJ, Javitch JA, Gether U. N-terminl truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-simulated phosphorylation without impairing transporter internalization. J Biol Chem. 2003;278:4990-5000.
    • (2003) J. Biol. Chem. , vol.278 , pp. 4990-5000
    • Granas, C.1    Ferrer, J.2    Loland, C.J.3    Javitch, J.A.4    Gether, U.5
  • 95
    • 0037805721 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase, protein kinase C, and MEK1/2 kinase regulation of dopamine transporters (DAT) require N-terminal DAT phosphoacceptor sites
    • Lin Z, Zhang PW, Zhu X, et al. Phosphatidylinositol 3-kinase, protein kinase C, and MEK1/2 kinase regulation of dopamine transporters (DAT) require N-terminal DAT phosphoacceptor sites. J Biol Chem. 2003;278:20162-20170.
    • (2003) J. Biol. Chem. , vol.278 , pp. 20162-20170
    • Lin, Z.1    Zhang, P.W.2    Zhu, X.3
  • 96
    • 0035120038 scopus 로고    scopus 로고
    • Protein tyrosine kinase inhibitors alter human dopamine transporter activity in Xenopus oocytes
    • Doolen S, Zahniser NR. Protein tyrosine kinase inhibitors alter human dopamine transporter activity in Xenopus oocytes. J Pharmacol Exp Ther. 2001;296:931-938.
    • (2001) J. Pharmacol. Exp. Ther. , vol.296 , pp. 931-938
    • Doolen, S.1    Zahniser, N.R.2
  • 97
    • 0034604649 scopus 로고    scopus 로고
    • Functional regulation of gamma-aminobutyric acid transporters by direct tyrosine phosphorylation
    • Law RM, Stafford A, Quick MW. Functional regulation of gamma-aminobutyric acid transporters by direct tyrosine phosphorylation. J Biol Chem. 2000;275:23986-23991.
    • (2000) J. Biol. Chem. , vol.275 , pp. 23986-23991
    • Law, R.M.1    Stafford, A.2    Quick, M.W.3
  • 98
    • 0035900674 scopus 로고    scopus 로고
    • Substrate-induced regulation of gamma-aminobutyric acid transporter trafficking requires tyrosine phosphorylation
    • Whitworth TL, Quick MW. Substrate-induced regulation of gamma-aminobutyric acid transporter trafficking requires tyrosine phosphorylation. J Biol Chem. 2001;276:42932-42937.
    • (2001) J. Biol. Chem. , vol.276 , pp. 42932-42937
    • Whitworth, T.L.1    Quick, M.W.2
  • 99
    • 1942533594 scopus 로고    scopus 로고
    • Regulation of a gamma-aminobutyric acid transporter by reciprocal tyrosine and serine phosphorylation
    • Quick MW, Hu J, Wang D, Zhang HY. Regulation of a gamma-aminobutyric acid transporter by reciprocal tyrosine and serine phosphorylation. J Biol Chem, 2004;279:15961-15967.
    • (2004) J. Biol. Chem. , vol.279 , pp. 15961-15967
    • Quick, M.W.1    Hu, J.2    Wang, D.3    Zhang, H.Y.4
  • 100
    • 0037335481 scopus 로고    scopus 로고
    • A regulated interaction of syntaxin 1A with the antidepressant-sensitive norepinephrine transporter establishes catecholamine clearance capacity
    • Sung U, Apparsundaram S, Galli A, et al, A regulated interaction of syntaxin 1A with the antidepressant-sensitive norepinephrine transporter establishes catecholamine clearance capacity. J Neurosci. 2003;23:1697-1709.
    • (2003) J. Neurosci. , vol.23 , pp. 1697-1709
    • Sung, U.1    Apparsundaram, S.2    Galli, A.3
  • 101
    • 0036683846 scopus 로고    scopus 로고
    • Determinants within the C-terminus of the human norepinephrine transporter dictate transporter trafficking, stability, and activity
    • Bauman PA, Blakely RD. Determinants within the C-terminus of the human norepinephrine transporter dictate transporter trafficking, stability, and activity. Arch Biochem Biophys. 2002;404:80-91.
    • (2002) Arch. Biochem. Biophys. , vol.404 , pp. 80-91
    • Bauman, P.A.1    Blakely, R.D.2
  • 102
    • 0242408745 scopus 로고    scopus 로고
    • The top 20 dopamine transporter mutants: Structure-function relationships and cocaine actions
    • Uhl GR, Lin Z. The top 20 dopamine transporter mutants: structure-function relationships and cocaine actions. Eur J Pharmacol. 2003;479:71-82.
    • (2003) Eur. J. Pharmacol. , vol.479 , pp. 71-82
    • Uhl, G.R.1    Lin, Z.2
  • 104
    • 0942276396 scopus 로고    scopus 로고
    • Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding
    • Loland CJ, Granas C, Javitch JA, Gether U. Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding. J Biol Chem. 2004;279:3228-3238.
    • (2004) J. Biol. Chem. , vol.279 , pp. 3228-3238
    • Loland, C.J.1    Granas, C.2    Javitch, J.A.3    Gether, U.4
  • 105
    • 2542477977 scopus 로고    scopus 로고
    • The second intracellular loop of the glycine transporter 2 contains crucial residues for glycine transport and phorbol ester-induced regulation
    • Fornes A, Nunez E, Aragon C, Lopez-Corcuera B. The second intracellular loop of the glycine transporter 2 contains crucial residues for glycine transport and phorbol ester-induced regulation. J Biol Chem. 2004;279:22934-22943.
    • (2004) J. Biol. Chem. , vol.279 , pp. 22934-22943
    • Fornes, A.1    Nunez, E.2    Aragon, C.3    Lopez-Corcuera, B.4
  • 106
    • 0033807807 scopus 로고    scopus 로고
    • Transport rates of GABA transporters: Regulation by the N-terminal domain and syntaxin 1A
    • Deken SL, Beckman ML, Boos L, Quick MW. Transport rates of GABA transporters: regulation by the N-terminal domain and syntaxin 1A. Nat Neurosci. 2000;3:998-1003.
    • (2000) Nat. Neurosci. , vol.3 , pp. 998-1003
    • Deken, S.L.1    Beckman, M.L.2    Boos, L.3    Quick, M.W.4
  • 107
    • 0035004752 scopus 로고    scopus 로고
    • Syntaxin 1A up-regulates GABA transporter expression by subcellular redistribution
    • Horton N, Quick MW. Syntaxin 1A up-regulates GABA transporter expression by subcellular redistribution. Mol Membr Biol. 2001;18:39-44.
    • (2001) Mol. Membr. Biol. , vol.18 , pp. 39-44
    • Horton, N.1    Quick, M.W.2
  • 108
    • 0141457715 scopus 로고    scopus 로고
    • Syntaxin 1A inhibits GABA flux, efflux, and exchange mediated by the rat brain GABA transporter GAT1
    • Wang D, Deken SL, Whitworth TL, Quick MW. Syntaxin 1A inhibits GABA flux, efflux, and exchange mediated by the rat brain GABA transporter GAT1. Mol Pharmacol. 2003;64:905-913.
    • (2003) Mol. Pharmacol. , vol.64 , pp. 905-913
    • Wang, D.1    Deken, S.L.2    Whitworth, T.L.3    Quick, M.W.4
  • 110
    • 0035026044 scopus 로고    scopus 로고
    • Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1
    • Torres GE, Yao WD, Mohn AR, et al. Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1. Neuron. 2001;30:121-134.
    • (2001) Neuron , vol.30 , pp. 121-134
    • Torres, G.E.1    Yao, W.D.2    Mohn, A.R.3
  • 111
    • 0035066885 scopus 로고    scopus 로고
    • Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis
    • Lee FJ, Liu F, Pristupa ZB, Niznik HB. Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis. FASEB J. 2001;15:916-926.
    • (2001) FASEB J. , vol.15 , pp. 916-926
    • Lee, F.J.1    Liu, F.2    Pristupa, Z.B.3    Niznik, H.B.4
  • 112
    • 0030744876 scopus 로고    scopus 로고
    • Mutation in the a-synuclein gene identified in families with Parkinson's disease
    • Polymeropoulos MH, Lavedan C, Leroy E, et al. Mutation in the a-synuclein gene identified in families with Parkinson's disease. Science. 1997;276:2045-2047.
    • (1997) Science , vol.276 , pp. 2045-2047
    • Polymeropoulos, M.H.1    Lavedan, C.2    Leroy, E.3
  • 113
    • 0842305633 scopus 로고    scopus 로고
    • Trypsin disrupts the trafficking of the human dopamine transporter by alpha-synuclein and its A30P mutant
    • Wersinger C, Vernier P, Sidhu A. Trypsin disrupts the trafficking of the human dopamine transporter by alpha-synuclein and its A30P mutant. Biochemistry. 2004;43:1242-1253.
    • (2004) Biochemistry , vol.43 , pp. 1242-1253
    • Wersinger, C.1    Vernier, P.2    Sidhu, A.3
  • 114
    • 0037104715 scopus 로고    scopus 로고
    • The multiple LIM domain-containing adaptor protein Hic-5 synaptically colocalizes and interacts with the dopamine transporter
    • Carneiro AM, Ingram SL, Beaulieu JM, et al. The multiple LIM domain-containing adaptor protein Hic-5 synaptically colocalizes and interacts with the dopamine transporter. J Neurosci. 2002;22:7045-7054.
    • (2002) J. Neurosci. , vol.22 , pp. 7045-7054
    • Carneiro, A.M.1    Ingram, S.L.2    Beaulieu, J.M.3
  • 115
    • 12944252971 scopus 로고    scopus 로고
    • Amphetamine-induced loss of human dopamine transporter activity: An internalization-dependent and cocaine-sensitive mechanism
    • Saunders C, Ferrer JV, Shi L, et al. Amphetamine-induced loss of human dopamine transporter activity: an internalization-dependent and cocaine-sensitive mechanism. Proc Natl Acad Sci USA. 2000;97:6850-6855.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 6850-6855
    • Saunders, C.1    Ferrer, J.V.2    Shi, L.3
  • 116
    • 0036295958 scopus 로고    scopus 로고
    • Cocaine increases dopamine uptake and cell surface expression of dopamine transporters
    • Daws LC, Callaghan PD, Moron JA, et al. Cocaine increases dopamine uptake and cell surface expression of dopamine transporters. Biochem Biophys Res Commun. 2002;290:1545-1550.
    • (2002) Biochem. Biophys. Res. Commun. , vol.290 , pp. 1545-1550
    • Daws, L.C.1    Callaghan, P.D.2    Moron, J.A.3
  • 117
    • 0036156518 scopus 로고    scopus 로고
    • Cocaine induction of dopamine transporter trafficking to the plasma membrane
    • Little KY, Elmer LW, Zhong H, Scheys JO, Zhang L. Cocaine induction of dopamine transporter trafficking to the plasma membrane. Mol Pharmacol. 2002;61:436-445.
    • (2002) Mol. Pharmacol. , vol.61 , pp. 436-445
    • Little, K.Y.1    Elmer, L.W.2    Zhong, H.3    Scheys, J.O.4    Zhang, L.5
  • 118
    • 0033534449 scopus 로고    scopus 로고
    • Regulation of gamma-aminobutyric acid (GABA) transporters by extracellular GABA
    • Bernstein EM, Quick MW. Regulation of gamma-aminobutyric acid (GABA) transporters by extracellular GABA. J Biol Chem. 1999;274:889-895.
    • (1999) J. Biol. Chem. , vol.274 , pp. 889-895
    • Bernstein, E.M.1    Quick, M.W.2
  • 119
    • 0034257160 scopus 로고    scopus 로고
    • Substrate-induced up-regulation of Na(+)-dependent glutamate transport activity
    • Munir M, Correale DM, Robinson MB. Substrate-induced up-regulation of Na(+)-dependent glutamate transport activity. Neurochem Int. 2000;37:147-162.
    • (2000) Neurochem. Int. , vol.37 , pp. 147-162
    • Munir, M.1    Correale, D.M.2    Robinson, M.B.3
  • 120
    • 0037117487 scopus 로고    scopus 로고
    • Substrates regulate gamma-aminobutyric acid transporters in a syntaxin 1A-dependent manner
    • Quick MW. Substrates regulate gamma-aminobutyric acid transporters in a syntaxin 1A-dependent manner. Proc Natl Acad Sci USA. 2002;99:5686-5691.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 5686-5691
    • Quick, M.W.1
  • 121
    • 23044457293 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in the human norepinephrine transporter gene impact expression, trafficking antidepressant interaction and protein kinase C regulation
    • Hahn MK, Mazei-Robison M, Blakely RD. Single nucleotide polymorphisms in the human norepinephrine transporter gene impact expression, trafficking antidepressant interaction and protein kinase C regulation. Mol Pharmacol. 2005;68:457-466.
    • (2005) Mol. Pharmacol. , vol.68 , pp. 457-466
    • Hahn, M.K.1    Mazei-Robison, M.2    Blakely, R.D.3
  • 122
    • 23844454012 scopus 로고    scopus 로고
    • Human serotonin transporter variants display selective insensitivity to protein kinase G and p38 mitogen activated kinase
    • Prasad HC, Zhu C, McCauley JL, et al. Human serotonin transporter variants display selective insensitivity to protein kinase G and p38 mitogen activated kinase. Proc Natl Acad Sci USA. 2005;102:11545-11550.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 11545-11550
    • Prasad, H.C.1    Zhu, C.2    McCauley, J.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.