Monoamine transporters and the neurobehavioral teratology of cocaine

Pharmacology Biochemistry and Behavior

Volumn 55, Issue 4, 1996, Pages 585-593

  Meyer, Jerrold S ^a   Shearman, Lauren P ^a   Collins, Lucille M ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

development; dopamine; norepinephrine; prenatal; serotonin; uptake

Indexed keywords

COCAINE; DOPAMINE; MONOAMINE; NORADRENALIN; SEROTONIN;

ANIMAL EXPERIMENT; BEHAVIOR; FETUS DEVELOPMENT; NONHUMAN; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; RAT; REVIEW; TERATOLOGY;

EID: 0030460121     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(96)00280-8     Document Type: Article

References (108)

1. 1. Abrams, R. M.; Burchfield, D. J.; Gerhardt, K. J.; Peters, A. J. M. Effect of cocaine on electrocortical activity in fetal sheep. Dev. Brain Res. 70:97-102; 1992.
2. 2. Ahmed, M. S.; Zhou, D.-H.; Maulik, D.; Eldefrawi, M. E. Characterization of a cocaine binding protein in human placenta. Life Sci. 46:553-561; 1990.
3. 3. Akbari, H. M.; Kramer, H. K.; Whitaker-Azmitia, P. M.; Spear, L. P.; Azmitia, E. C. Prenatal cocaine exposure disrupts the development of the serotonergic system. Brain Res. 572: 57-63; 1992.
4. 4. Amara, S. G.; Kuhar, M. J. Neurotransmitter transporters: Recent progress. Annu. Rev. Neurosci. 16:73-93; 1993.
5. 5. Azuma, S. D.; Chasnoff, I. J. Outcome of children prenatally exposed to cocaine or other drugs: A path analysis of three-year data. Pediatrics 92:396-402; 1993.
6. 6. Barker, E. L.; Kimmel H. L.; Blakely, R. D. Chimeric human and rat serotonin transporters reveal domains involved in recognition of transporter ligands. Mol. Pharmacol. 46:799-807; 1994.
7. IA receptor-mediated neuroendocrine responses in male but not female rat progeny after prenatal cocaine: Evidence for gender differences. J. Pharmacol. Exp. Ther. 271:1453-1461; 1994.
8. 125I]RTI-55 to dopamine and serotonin transporters in rat brain. Synapse 12:27-36; 1992.
9. 9. Brazelton, T. B. Neonatal behavioral assessment scale, 2nd ed. Philadelphia: J. B. Lippincott; 1984.
10. 3H]dopamine uptake in rat mesencephalic cells in primary cultures: pharmacologic selectivity of embryonic cocaine sites. Dev. Brain Res. 75:13-17; 1993.
11. 11. Burchfield, D. J.; Graham, E. M.; Abrams, R. M.; Gerhardt, K. J. Cocaine alters behavioral states in fetal sheep. Dev. Brain Res. 56:41-45; 1990.
12. 12. Byrnes, J. J.; Pritchard, G. A.; Koff, J. M.; Miller, L. G. Prenatal cocaine exposure: decreased sensitization to cocaine and decreased striatal dopamine transporter binding in offspring. Neuropharmacology 32:721-723; 1993.
13. 13. Cabrera, T. M.; Yracheta, J. M.; Li, Q.; Levy, A. D.; Van De Kar, L.; Battaglia, G. Prenatal cocaine produces deficits in serotonin mediated neuroendocrine responses in adult rat progeny: Evidence for long-term functional alterations in brain serotonin pathways. Synapse 15:158-168; 1993.
14. 14. Cerruti, C.; Pilotte, N. S.; Uhl, G.; Kuhar, M. J. Reduction in dopamine transporter mRNA after cessation of repeated cocaine administration. Mol. Brain Res. 22:132-138; 1994.
15. 15. Chasnoff, I. J.; Burns, W. J.; Schnell, S. H.; Burns, K. A. Cocaine use in pregnancy. New Engl. J. Med. 313:666-669; 1985.
16. 16. Claye, L. H.; Akunne, H. C.; Davis, M. D.; DeMattos, S.; Soliman, K. F. A. Behavioral and neurochemical changes in the dopaminergic system after repeated cocaine administration. Mol. Neurobiol. 11:55-66; 1995.
17. 17. Coles, C. D. Saying "goodbye" to the "crack baby." Neurotoxicol. Teratol. 15:290-292; 1993.
18. 18. Coles, C. D.; Platzman, K. A.; Smith, I.; James, M. E.; Falek, A. Effects of cocaine and alcohol use in pregnancy on neonatal growth and neurobehavioral status. Neurotoxicol. Teratol. 14: 23-33; 1992.
19. 19. Collins, L. M.; Meyer, J. S. Prenatal cocaine alters dopamine transporter binding in postnatal day 10 rat striatum. Synapse 23:335-343; 1996.
20. 20. Cool, D. R.; Leibach, F. H.; Ganapathy, V. High-affinity paroxetine binding to the human placental serotonin transporter. Am. J. Physiol. 259:C196-C204; 1990.
21. 3H]norepinephrine in the rat brain. J. Neurochem. 18:2061-2078; 1971.
22. 22. Cunningham, K. A.; Paris, J. M.; Goeders, N. E. Chronic cocaine enhances serotonin autoregulation and serotonin uptake binding. Synapse 11:112-123; 1992.
23. 23. Dackis, C. A.; Marcy, A.; Martin, D.; Pottash, A. L. C.; Gold, M. S. Platelet serotonin transporter in cocaine patients. In: Harris, L. D., ed. Problems of drug dependence, 1989. NIDA Research Monograph 95. Washington, D.C.: U. S. Government Printing Office; 1989:164-169.
24. 24. Day, N. L.; Richardson, G. A. Cocaine use and crack babies: science, the media, and miscommunication. Neurotoxicol. Teratol. 15:293-294; 1993.
25. 25. De Bartolomeis, A.; Austin, M. C.; Goodwin, G. A.; Spear, L. P.; Pickar, D.; Crawley, J. N. Dopaminergic and peptidergic mRNA levels in juvenile rat brain after prenatal cocaine treatment. Mol. Brain Res. 21:321-332; 1994.
26. 26. Dow-Edwards, D. L. Effects of developmental cocaine exposure on acoustic startle responding in the adult rat. Neurotoxicol. Teratol. 17:376; 1995.
27. 27. Ferrari, C. M.; Riley, A. L. Effect of prenatal cocaine on the acquisition of cocaine-induced taste aversions. Neurotoxicol. Teratol. 16:17-23; 1994.
28. 28. Frank, D. A.; Bresnahan, K.; Zuckerman, B. S. Maternal cocaine use: Impact on child health and development. Adv. Pediat. 40:65-99; 1993.
29. 29. Frank, D. A.; Zuckerman, B. S. Children exposed to cocaine prenatally: pieces of the puzzle. Neurotoxicol. Teratol. 15:298-300; 1993.
30. 125I]RTI-55. J. Chem. Neuroanat. 7:13-23; 1994.
31. 31. Fujita, M.; Shimada, S.; Nishimura, T.; Uhl, G. R.; Tohyama, M. Ontogeny of dopamine transporter mRNA expression in the rat brain. Mol. Brain Res. 19:222-226; 1993.
32. 32. Giros, B.; Jaber. M.; Jones, S. R.; Wightman, R. M.; Caron, M. G. Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 379:606-612; 1996.
33. 33. Goodwin, G. A.; Moody, C. A.; Spear, L. P. Prenatal cocaine exposure increases the behavioral sensitivity of neonatal rat pups to ligands active at opiate receptors. Neurotoxicol. Teratol. 15:425-431; 1993.
34. 34. Graham, D.; Langer, S. Z. Advances in sodium-ion coupled biogenic amine transporters. Life Sci. 51:631-645; 1992.
35. 35. Hansson, S. R.; Mezey, E; Hoffman, B. J. Serotonin transporter mRNA localization in the developing rat embryo, Soc. Neurosci. Abstr. 21:865; 1995.
36. 36. Hepper, P. G. Human fetal behaviour and maternal cocaine use: A longitudinal study. Neurotoxicology 16:139-144; 1995.
37. 37. Heyser, C. J.; Chen, W.-J.; Miller, J.; Spear, N. E.; Spear, L. P. Prenatal cocaine exposure induces deficits in Pavlovian conditioning and sensory preconditioning among infant rat pups. Behav. Neurosci. 104:955-963; 1990.
38. 38. Heyser, C. J.; Goodwin, G. A.; Moody, C. A.; Spear, L. P. Prenatal cocaine exposure attenuates cocaine-induced odor preference in infant rats. Pharmacol. Biochem. Behav. 42:169-173; 1992.
39. 39. Heyser, C. J.; Miller, J. S.; Spear, N. E.; Spear, L. P. Prenatal exposure to cocaine disrupts cocaine-induced conditioned place preference in rats. Neurotoxicol. Teratol. 14: 57-64; 1992.
40. 40. Heyser, C. J.; Rajachandran, L.; Spear, N. E.; Spear, L. P. Responsiveness to cocaine challenge in adult rats following prenatal exposure to cocaine. Psychopharmacology 116:45-55; 1994.
41. 41. Heyser, C. J.; Spear, N. E.; Spear, L. P. Effects of prenatal exposure to cocaine on Morris water maze performance in adult rats. Behav. Neurosci. 109:734-743; 1995.
42. 42. Hoyme, H. E.; Lyons, K.; Dixon, S. D.; Jewett, T.; Hanson, J. W.; Robinson, L. K.; Msall, M. E.; Allanson, J. E. Prenatal cocaine exposure and fetal vascular disruption. Pediatrics 85:743-747; 1990.
43. 43. Hume, R. F. Jr.; O'Donnell, K. J.; Stanger, C. L.; Killam, A. P.; Gingras, J. L. In utero cocaine exposure: observations of fetal behavioral state may predict neonatal outcome. Am. J. Obstet. Gynecol. 161:685-690; 1989.
44. 44. Hurd, Y. L.; Herkenham, M. Molecular alterations in the neostriatum of human cocaine addicts. Synapse 13:357-369; 1993.
45. 45. Hutchings, D. E. The puzzle of cocaine's effects following maternal use during pregnancy: Are there reconcilable differences? Neurotoxicol. Teratol. 15:281-286; 1993.
46. 46. Hyde, C. E.; Bennett, B. A. Similar properties of fetal and adult amine transporters in the rat brain. Brain Res. 646:118-123; 1994.
47. 47. Ivgy-May, N.; Tamir, H.; Gershon, M. D. Synaptic properties of serotonergic growth cones in developing rat brain. J. Neurosci. 14:1011-1029; 1994.
48. 48. Johns, J. M.; Means, M. J.; Anderson, D. R.; Means, L. W.; McMillen, B. A. Prenatal exposure to cocaine II: Effects on open-field activity and cognitive behavior in Sprague-Dawley rats. Neurotoxicol. Teratol. 14:343-349; 1992.
49. 125I]RTI-55. Synapse 12:99-111; 1992.
50. 50. Keller, R. W. Jr.; Maisonneuve, I. M.; Nuccio, D. M.; Carlson, J. N.; Glick, S. D. Effects of prenatal cocaine exposure on the nigrostriatal dopamine system: an in vivo microdialysis study in the rat. Brain Res. 634:266-274; 1994.
51. 51. Koff, J. M.; Miller, L. G. Prenatal cocaine exposure: Increased striatal dopamine transporter binding in offspring at 3 and 6 months of age. Brain Res. Bull. 33:223-224; 1994.
52. 52. Koff, J. M.; Shuster, L.; Miller, L. G. Chronic cocaine administration is associated with behavioral sensitization and time-dependent changes in striatal dopamine transporter binding. J. Pharmacol. Exp. Ther. 268:277-282; 1994.
53. 53. Koren, G. Cocaine and the human fetus: The concept of teratophilia. Neurotoxicol. Teratol. 15:301-304; 1993.
54. 54. Lauder, J. M. Neurotransmitters as growth regulatory signals: role of receptors and second messengers. Trends Neurosci. 16:233-240; 1993.
55. 3H]-GBR12935 to measure dopaminergic nerve terminal growth into the developing rat striatum. Dev. Brain Res. 67:375-377; 1992.
56. 56. Leslie, C. A.; Robertson, M. W.; Jung, A. B.; Liebermann, J.; Bennett, J. P. Jr. Effects of prenatal cocaine exposure upon postnatal development of neostriatal dopaminergic function. Synapse 17:210-215; 1994.
57. 57. Lester, B. M.; Corwin, M. J.; Sepkoski, C.; Seifer, R.; Peucker, M.; McLaughlin, S.; Golub, H. L. Neurobehavioral syndromes in cocaine-exposed newborn infants. Child Dev. 62:694-705; 1991.
58. 58. Letchworth, S. R.; Daunais, J. B.; Porrino, L. J. Chronic cocaine administration decreases serotonin transporter mRNA. Soc. Neurosci. Abstr. 21:716; 1995.
59. 59. Levin, E. D.; Seidler, F. J. Sex-related spatial learning differences after prenatal cocaine exposure in the young adult rat. Neurotoxicology 14:23-28; 1993.
60. 125I]RTI-55 binding to cocaine-sensitive dopaminergic and serotonergic uptake sites in the human brain. J. Neurochem. 61:1996-2006; 1993.
61. 3H]WIN 35,428 binding-sites in human striatum. Brain Res. 628:17-25; 1993.
62. 1H-imipramine binding in heroin and cocaine addicts. Mol. Neurobiol. 11:21-29; 1995.
63. 63. Meyer, J. S.; Robinson, P.; Todtenkopf, M. S. Prenatal cocaine treatment reduces haloperidol-induced catalepsy on postnatal day 10. Neurotoxicol. Teratol. 16:193-199; 1994.
64. 64. Meyer, J. S.; Shearman, L. P.; Collins, L. M.; Maguire, R. L. Cocaine binding sites in fetal rat brain: implications for prenatal cocaine action. Psychopharmacology 112:445-451; 1993.
65. 65. Meyer, J. S.; Sherlock, J. D.; MacDonald, N. R. Effects of prenatal cocaine on behavioral responses to a cocaine challenge on postnatal day 11. Neurotoxicol. Teratol. 14:183-189; 1992.
66. 66. Moody, C. A.; Frambes, N. A.; Spear, L. P. Psychopharmacological responsiveness to the dopamine agonist quinpirole in normal weanlings and in weanling offspring exposed gestationally to cocaine. Psychopharmacology 108:256-262; 1992.
67. 67. Neuspiel, D. R.; Hamel, S. C. Cocaine and infant behavior. Dev. Behav. Pediat. 12:55-64; 1991.
68. 68. Nulman, I.; Rovet, J.; Altmann, D.; Bradley, C; Einarson, T.; Koren, G. Neurodevelopment of adopted children exposed in utero to cocaine. Can. Med. Assoc. J. 151:1591-1597; 1994.
69. 69. Olsen, G. D. Potential mechanisms of cocaine-induced developmental neurotoxicity: a minireview. Neurotoxicology 16:159-168; 1995.
70. 70. Peris, J.; Coleman-Hardee, M.; Millard, W. J. Cocaine in utero enhances the behavioral response to cocaine in adult rats. Pharmacol. Biochem. Behav. 42:509-515; 1992.
71. 71. Pilotte, N. S.; Sharpe, L. G.; Kuhar, M. J. Withdrawal of repeated intravenous infusions of cocaine persistently reduces binding to dopamine transporters in the nucleus accumbens of Lewis rats. J. Pharmacol. Exp. Ther. 269:963-969; 1994.
72. 72. Prasad, P. D.; Leibach, F. H.; Mahesh, V. B.; Ganapathy, V. Human placenta as a target organ for cocaine action: Interaction of cocaine with the placenta! serotonin transporter. Placenta 15:267-278; 1994.
73. 1H]GBR 12,935 binding. Mol. Pharmacol. 45:125-135; 1994.
74. 74. Ramamoorthy, S.; Bauman, A. L.; Moore, K. R.; Han, H.; Yang-Feng, T.; Chang, A. S.; Ganapathy, V.; Blakely, R. D. Antidepressant-and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization. Proc. Nat. Acad. Sci. USA 90:2542-2546; 1993.
75. 75. Ramamoorthy, S.; Prasad, P. D.; Kulanthaivel, P.; Leibach, F. H.; Blakely, R. D.; Ganapathy, V. Expression of a cocaine-sensitive norepinephrine transporter in the human placcntal syncytiotrophoblast. Biochemistry 32:1346-1353; 1993.
76. 76. Richardson, G. A.; Day, N. L. Maternal and neonatal effects of moderate cocaine use during pregnancy. Neurotoxicol. Teratol. 13:455-460; 1991.
77. 77. Richardson, G.; Day, N.; Goldschmidt, L. A longitudinal study of prenatal cocaine exposure: 3-year outcome. Neurotoxicol. Teratol. 17:383-384; 1995.
78. 78. Riley, E. P.; Foss, J. A. The acquisition of passive avoidance, active avoidance, and spatial navigation tasks by animals prenatally exposed to cocaine. Neurotoxicol. Teratol. 13:559-564; 1991.
79. 79. Ross, M. G.; Nijland, M. J. M.; Kullama, L. K.; Chan, K. Cocaine stimulation of ovine fetal swallowing. Dev, Brain Res. 87:120-124; 1995.
80. 80. Saadouni, S.; Refahi-Lyamani, F.; Costentin, J.; Bonnet, J.-J. Cocaine and GBR 12783 recognize nonidentical, overlapping binding domains on the dopamine neuronal carrier. Eur, J. Pharmacol. 268:187-197; 1994.
81. 81. Sailer, C. F.; Kreamer, L. D.; Adamovage, L. A.; Salama, A. I. Dopamine receptor occupany in vivo: measurement using N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ). Life Sci. 45:917-929; 1989.
82. 2 dopamine binding associated with an increase in ligand affinity. Pharmacol. Biochem. Behav. 37:371-373; 1990.
83. 125I]RTI-55-labeled cocaine binding sites in fetal and adult rat brain. J. Pharmacol. Exp. Ther. 277:1770-1783; 1996.
84. 84. Shearman, L. P.; Koman. A.; Meyer, J. S. Prenatal ontogeny of norepinephrine transporter binding in the rat brain. Soc. Neurosci. Abstr. 21:705; 1995.
85. 3H]nisoxetine. Soc. Neurosci. Abstr. 20:596; 1994.
86. 86. Shearman, L. P.; Meyer, J. S. Cocaine treatment alters norepinephrine transporter binding in gestational day (GD) 20 rat placenta. Neurotoxicol. Teratol. 17:385; 1995.
87. 87. Simonik, D. K.; Robinson, S. R.; Smotherman, W. P. Cocaine alters behavior in the rat fetus. Behav. Neurosci. 107:867-875; 1993.
88. 88. Simonik, D. K.; Robinson, S. R.; Smotherman, W. P. Central administration of cocaine produces age-dependent effects on behavior in the fetal rat. Behav. Neurosci. 108:1179-1187; 1994.
89. 89. Simonik, D. K.; Robinson, S. R.; Smotherman, W. P. Cocaine alters cyclic motor activity in the fetal rat. Dev. Psychobiol. 27:489-501; 1994.
90. 90. Slutsker, L. Risks associated with cocaine use during pregnancy. Obstet. Gynecol. 79:778-789; 1992.
91. 91. Smith, R. F.; Mattran, K. M.; Kurkjian, M. F.; Kurtz, S. L. Alterations in offspring behavior induced by chronic prenatal cocaine dosing. Neurotoxicol. Teratol. 11:35-38; 1989.
92. 92. Spear, L. P.; Kirstein, C. L.; Bell, J.; Yoottanasumpun, V.; Greenbaum, R.; O'Shea, J.; Hoffmann, H.; Spear, N. E. Effects of prenatal cocaine exposure on behavior during the early postnatal period, Neurotoxicol. Teratol. 11:57-63; 1989.
93. 3H]mazindol-labelled dopamine uptake sites in the rat striatum following prenatal cocaine exposure. Brain Res. 637:345-348; 1994.
94. 125I]RTI-55: in vitro binding and autoradiographic characterization. J. Neurochem. 62:549-556; 1994.
95. 95. Staley, J. K.; Hearn, W. L.; Ruttenber, A. J.; Wetli, C. V.; Mash, D. C. High affinity cocaine recognition sites on the dopamine transporter are elevated in fatal cocaine overdose victims. J. Pharmacol. Exp. Ther. 271:1678-1685; 1994.
96. 3H]Nisoxetine: a new radioligand for norepinephrine uptake sites in brain. Eur. J. Pharmacol. 191:239-243; 1990.
97. 2 dopamine receptor and dopamine transporter gene expression in the rat mesencephalon. Neurosci. Lett. 166:48-50; 1994.
98. 98. van Baar, A. Development of infants of drug-dependent mothers. J. Child Psychol. Psychiat. 31:911-920; 1990.
99. 99. Volkow, N. D.; Fowler, J. S. Brain imaging studies of the cocaine addict: implications for reinforcement and addiction. In: Hammer, R. P. Jr.. ed. The neurobiology of cocaine: cellular and molecular mechanisms. Boca Raton: CRC Press; 1995:65-78.
100. 100. Voorn, P.; Kalsbeek, A.; Jorritsma-Byham, B.; Groenewegen, H. J. The pre-and postnatal development of dopaminergic cell groups in the ventral mesencephalon and the dopaminergic innervation of the striatum of the rat. Neuroscience 25:857-888; 1988.
101. 101. Vorhees, C. V. Long-term effects of developmental exposure to cocaine on learned and unlearned behaviors. In: Wetherington, C. L.; Smeriglio, V. L.; Finnegan, L. P., ed. Behavioral studies of drug-exposed offspring: methodological issues in human and animal research. NIDA Research Monograph 164. Washington, D.C.: U. S. Government Printing Office; 1989:3-52.
102. 102. Vorhees, C. V.; Reed, T. M.; Acuff-Smith, K. D.; Schilling, M. A.; Cappon, G. D.; Fisher, J. E.; Pu, C. Long-term learning deficits and changes in unlearned behaviors following in utero exposure to multiple daily doses of cocaine during different exposure periods and maternal plasma cocaine concentrations. Neurotoxicol. Teratol. 17:253-264; 1995.
103. 103. Webster, W. S.; Brown-Woodman, P. D. C. Cocaine as a cause of congenital malformations of vascular origin: Experimental evidence in the rat. Teratology 41:689-697; 1990.
104. 3H-GBR 12,935 are differentially regulated by chronic cocaine self-administration. J. Neurosci. 14:2966-2979; 1994.
105. 105. Woods, N. S.; Eyler, F. D.; Behnke, M.; Conlon, M. Cocaine use during pregnancy: Maternal depressive symptoms and infant neurobehavior over the first month. Infant Behav. Dev. 16:83-98; 1993.
106. 106. Woolverton, W. L.; Johnson, K. M. Neurobiology of cocaine abuse. Trends Pharmacol. Sci. 13:193-200; 1992.
107. 107. Xia, Y.; Goebel, D. J.; Kapatos, G.; Bannon, M. J. Quantitation of rat dopamine transporter mRNA: effects of cocaine treatment and withdrawal. J. Neurochem. 59:1179-1182; 1992.
108. 108. Zahniser, N. R.; Gerhardt, G. A.; Cass, W. A. Chronic cocaine action on the dopamine transporter. In Hammer, R. P. Jr., ed. The neurobiology of cocaine: cellular and molecular mechanisms. Boca Raton: CRC Press; 1995:181-197.