Therapeutic treatment with heat-killed Mycobacterium vaccae (SRL172) in a mild and severe mouse model for allergic asthma

European Journal of Pharmacology

Volumn 470, Issue 3, 2003, Pages 193-199

  Smit, Joost J ^a,b   Van Loveren, Henk ^b   Hoekstra, Maarten O ^c   Van Der Kant, Patrick A A ^a   Folkerts, Gert ^a   Nijkamp, Frans P ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Allergy; Asthma; Hygiene hypothesis; Mycobacterium vaccae

Indexed keywords

ALLERGEN; ALUMINUM; IMMUNOGLOBULIN E; INTERLEUKIN 5; MYCOBACTERIUM VACCINE; OVALBUMIN; SODIUM CHLORIDE; SRL 172;

AEROSOL; AIRWAY; ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ARTICLE; COLONY FORMING UNIT; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE MODEL; DISEASE SEVERITY; DRUG EFFECT; EOSINOPHILIA; HEAT; HYPERSENSITIVITY; INHALATION; MALE; MOUSE; MYCOBACTERIUM VACCAE; NONHUMAN; PRIORITY JOURNAL; PROVOCATION TEST; SENSITIZATION;

EID: 0038206470     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(03)01794-1     Document Type: Article

References (21)

1. Broide D., Schwarze J., Tighe H., Gifford T., Nguyen M.D., Malek S., Van Uden J., Martin-Orozco E., Gelfand E.W., Raz E. Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice. J. Immunol. 161:1998;7054-7062.
2. Erb K.J., Holloway J.W., Sobeck A., Moll H., Le Gros G. Infection of mice with Mycobacterium bovis-bacillus Calmette-Guérin (BCG) suppresses allergen-induced airway eosinophilia. J. Exp. Med. 187:1998;561-569.
3. Hamelmann E., Schwarze J., Takeda K., Oshiba A., Larsen G.L., Irvin C.G., Gelfand E.W. Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography. Am. J. Respir. Crit. Care Med. 156:1997;766-775.
4. Hansen G., Yeung V.P., Berry G., Umetsu D.T., DeKruyff R.H. Vaccination with heat-killed Listeria as adjuvant reverses established allergen-induced airway hyperreactivity and inflammation: role of CD8+ T cells and IL-18. J. Immunol. 164:2000;223-230.
5. Hartert T.V., Peebles R.S. Jr. Epidemiology of asthma: the year in review. Curr. Opin. Pulm. Med. 6:2000;4-9.
6. Hattori H., Okano M., Yamamoto T., Yoshino T., Yamashita Y., Watanabe T., Satoskar A.R., Harn D.A., Nishizaki K. Intranasal application of purified protein derivative suppresses the initiation but not the exacerbation of allergic rhinitis in mice. Clin. Exp. Allergy. 32:2002;951-959.
7. Hernandez-Pando R., Rook G.A. The role of TNF-alpha in T-cell-mediated inflammation depends on the Th1/Th2 cytokine balance. Immunology. 82:1994;591-595.
8. Hernandez-Pando R., Pavon L., Arriaga K., Orozco H., Madrid-Marina V., Rook G. Pathogenesis of tuberculosis in mice exposed to low and high doses of an environmental mycobacterial saprophyte before infection. Infect. Immun. 65:1997;3317-3327.
9. Herz U., Gerhold K., Gruber C., Braun A., Wahn U., Renz H., Paul K. BCG infection suppresses allergic sensitization and development of increased airway reactivity in an animal model. J. Allergy Clin. Immunol. 102:1998;867-874.
10. Hessel E.M., Van Oosterhout A.J., Hofstra C.L., De Bie J.J., Garssen J., Van Loveren H., Verheyen A.K., Savelkoul H.F., Nijkamp F.P. Bronchoconstriction and airway hyperresponsiveness after ovalbumin inhalation in sensitized mice. Eur. J. Pharmacol. 293:1995;401-412.
11. Hopfenspirger M.T., Agrawal D.K. Airway hyperresponsiveness, late allergic response, and eosinophilia are reversed with mycobacterial antigens in ovalbumin-presensitized mice. J. Immunol. 168:2002;2516-2522.
12. Hylkema M.N., Timens W., Luinge M., Van Der Werf N., Hoekstra M.O. The effect of bacillus Calmette-Guérin immunization depends on the genetic predisposition to Th2-type responsiveness. Am. J. Respir. Cell Mol. Biol. 27:2002;244-249.
13. Janssen R., Kruisselbrink A., Hoogteijling L., Lamb J.R., Young D.B., Thole J.E. Analysis of recombinant mycobacteria as T helper type 1 vaccines in an allergy challenge model. Immunology. 102:2001;441-449.
14. Major T., Wohlleben G., Reibetanz B., Erb K.J. Application of heat killed Mycobacterium bovis-BCG into the lung inhibits the development of allergen-induced Th2 responses. Vaccine. 20:2002;1532-1540.
15. Mojtabavi N., Dekan G., Stingl G., Epstein M.M. Long-lived th2 memory in experimental allergic asthma. J. Immunol. 169:2002;4788-4796.
16. Rook G.A., Stanford J.L. Give us this day our daily germs. Immunol. Today. 19:1998;113-116.
17. Sano K., Haneda K., Tamura G., Shirato K. Ovalbumin (OVA) and Mycobacterium tuberculosis bacilli cooperatively polarize anti-OVA T-helper (Th) cells toward a Th1-dominant phenotype and ameliorate murine tracheal eosinophilia. Am. J. Respir. Cell Mol. Biol. 20:1999;1260-1267.
18. Strachan D.P. Hay fever, hygiene, and household size. BMJ. 299:1989;1259-1260.
19. Wang C.C., Rook G.A. Inhibition of an established allergic response to ovalbumin in BALB/c mice by killed Mycobacterium vaccae. Immunology. 93:1998;307-313.
20. Zuany-Amorim C., Manlius C., Trifilieff A., Brunet L.R., Rook G., Bowen G., Pay G., Walker C. Long-term protective and antigen-specific effect of heat-killed Mycobacterium vaccae in a murine model of allergic pulmonary inflammation. J. Immunol. 169:2002;1492-1499.
21. Zuany-Amorim C., Sawicka E., Manlius C., Le Moine A., Brunet L.R., Kemeny D.M., Bowen G., Rook G., Walker C. Suppression of airway eosinophilia by killed Mycobacterium vaccae-induced allergen-specific regulatory T-cells. Nat. Med. 8:2002;625-629.