Dysregulation of signaling pathways in CD45-deficient NK cells leads to differentially regulated cytotoxicity and cytokine production

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 18, 2006, Pages 7012-7017

  Hesslein, David G T ^a   Takaki, Rayna ^a,b   Hermiston, Michelle L ^a   Weiss, Arthur ^a,b   Lanier, Lewis L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Tyrosine phosphatase

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD16 ANTIGEN; CD45 ANTIGEN; CHEMOKINE; CYTOKINE; INTERLEUKIN 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; NATURAL KILLER CELL RECEPTOR; NATURAL KILLER CELL RECEPTOR NKG2D; PROTEIN LY49D; PROTEIN LY49H; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE; STRESS ACTIVATED PROTEIN KINASE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOLYSIS; CYTOTOXICITY; EFFECTOR CELL; ENZYME ACTIVATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

AMINO ACID MOTIFS; ANIMALS; ANTIGENS, CD45; CHEMOKINES; CYTOKINES; ENZYME ACTIVATION; KILLER CELLS, NATURAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION; TYROSINE;

EID: 33646491409     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0601851103     Document Type: Article

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