The regulatory role of CD45 on rat NK cells in target cell lysis

Journal of Immunology

Volumn 163, Issue 1, 1999, Pages 71-76

  Giezeman Smits, Katinka M ^a   Gorter, Arko ^a   Van Vlierberghe, Ronald L P ^a   Eendenburg, Jaap D H V ^a   Eggermont, Alexander M M ^b   Fleuren, Gert Jan ^a   Kuppen, Peter J K ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; CELL PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCLONAL ANTIBODY;

ANIMAL CELL; ANTIGEN BINDING; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; CELL FUNCTION; DEPHOSPHORYLATION; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; TARGET CELL; TUMOR CELL LINE;

ANIMALS; ANTIBODIES, BLOCKING; ANTIBODIES, MONOCLONAL; ANTIBODY-DEPENDENT CELL CYTOTOXICITY; ANTIGEN-ANTIBODY REACTIONS; ANTIGENS, CD45; CELLS, CULTURED; CYTOTOXICITY TESTS, IMMUNOLOGIC; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; MICE; PROTEIN ISOFORMS; RATS; TUMOR CELLS, CULTURED;

EID: 0033168614     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Trowbridge, I. S., and M. L. Thomas. 1994. CD45: an emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development. Annu. Rev. Immunol. 12:85.
2. Weaver, C. T., J. T. Pingel, J. O. Nelson, and M. L. Thomas. 1992. CD45: a transmembrane protein tyrosine phosphatase involved in the transduction of antigenic signals. Biochem. Soc. Trans. 20:169.
3. Thomas, M. L. 1989. The leukocyte common antigen family. Annu. Rev. Immunol. 7:339.
4. Ledbetter, J. A., N. K. Tonks, E. H. Fischer, and E. A. Clark. 1988. CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cells. Proc. Natl. Acad. Sci. USA 85:8628.
5. López-Botet, M., L. Moretta, and J. Strominger. 1996. NK-cell receptors and recognition of MHC class 1 molecules. Immunol. Today 17:212.
6. Raulet, D. H. 1996. Recognition events that inhibit and activate natural killer cells. Curr. Opin. Immunol. 8:372.
7. Timonen, T. 1997. Natural killer cells: endothelial interactions, migration, and target cell recognition. J. Leukocyte Biol. 62:693.
8. Starling, G. C., S. E. Davidson, J. L. McKenzie, and D. N. J. Hart. 1987. Inhibition of natural killer-cell mediated cytolysis with monoclonal antibodies to restricted and non-restricted epitopes of the leucocyte common antigen. Immunology 61:351.
9. Sparrow, R. L., and I. F. C. McKenzie. 1983. A function for human T200 in natural killer cytolysis. Transplantation 36:166.
10. Starling, G. C., and D. N. J. Hart. 1990. CD45 molecule cross-linking inhibits natural killer cell-mediated lysis independently of lytic triggering. Immunology 71:190.
11. Poggi, A., R. Pardi, N. Pella, L. Morelli, S. Sivori, M. Vitale, V. Revello, A. Moretta, and L. Moretta. 1993. CD45-mediated regulation of LFA1 function in human natural killer cells: anti-CD45 monoclonal antibodies inhibit the calcium mobilization induced via LFA1 molecules. Eur. J. Immunol. 23:2454.
12. Bell, G. M., G. M. Dethloff, and J. B. Imboden. 1993. CD45-negative mutants of a rat NK cell line fail to lyse tumor target cells. J. Immunol. 151:3646.
13. Fukumoto, T., W. R. McMaster, and A. F. Williams. 1982. Mouse monoclonal antibodies against rat major histocompatibility antigens: two Ia antigens and expression of Ia and class 1 antigens in rat thymus. Eur. J. Immunol. 12:237.
14. Parker, K. E., C. A. Carter, and J. W. Fabre. 1990. A rat class I cDNA clone with an Alu-like sequence and mapping to two genes in RT1.C/E. Immunogenetics 31:211.
15. Sunderland, C. A., W. R. McMaster, and A. F. Williams. 1979. Purification with monoclonal antibody of a predominant leukocyte-common antigen and glycoprotein from rat thymocytes. Eur. J. Immunol. 9:155.
16. Chambers, W. H., N. L. Vujanovic, A. B. DeLeo, M. W. Olszowy, R. B. Herberman, and J. C. Hiserodt. 1989. Monoclonal antibody to a triggering structure expressed on rat natural killer cells and adherent lymphokine-activated killer cells. J. Exp. Med. 169:1373.
17. Smits, K. M., P. J. K. Kuppen, A. M. M. Eggermont, T. Tamatani, M. Miyasaka, and G. J. Fleuren. 1994. Rat interleukin-2-activated natural killer (A-NK) cell-mediated lysis is determined by the presence of CD18 on A-NK cells and the absence of major histocompatibility complex class I on target cells. Eur. J. Immunol. 24:171.
18. Imboden, J. B., E. C. Eriksson, M. McCutcheon, C. W. Reynolds, and W. E. Seaman. 1989. Identification and characterization of a cell-surface molecule that is selectively induced on rat lymphokine-activated killer cells. J. Immunol. 143:3100.
19. Beun, G. D M., J. D. H. van Eendenburg, W. E. Corver, C. J. H. Van de Velde, and G. J. Fleuren. 1992. T-cell retargeting using bispecific monoclonal antibodies in a rat colon carcinoma model: significant bispecific lysis of syngeneic colon carcinoma CC531 is critically dependent on prolonged preactivatior of effector T-lymphocytes by immobilized anti-T-cell receptor antibody. J. Immunother. 11: 238.
20. Giezeman-Smits, K. M., P. J. K. Kuppen, N. G. Ensink, A. M. M. Eggermont, F. Stals, K. Wonigeit, and G. J. Fleuren. 1996. The role of MHC class I expression in rat NK cell-mediated lysis of syngeneic tumor cells and virus-infected cells. Immunobiology 195:286.
21. Marquet, R. L., D. L Westbroek, and J. Jeekel. 1984. Interferon treatment of a transplantable rat colon adenocarcinoma: importance of tumor site. Int. J. Cancer 33:689.
22. Shen, F., X.-L. Xu, L. H. Graf, and A. S.-F. Chong. 1995. CD45-cross-linking stimulates IFN-γ production in NK cells. J. Immunol. 154:644.
23. lck-mediated tyrosine phosphorylation and IFN-γ production. J. Immunol. 155:5241.
24. Olcese, L., P. Lang, F. Vély, A. Cambiaggi, D. Marguet, M. Bléry, K. L. Hippen, R. Biassoni, A. Moretta, L. Moretta, J. C. Cambier, and E. Vivier. 1996. Human and mouse killer cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases. J. Immunol. 156:4531.
25. Campbell, K. S., M. Dessing, M. Lopez-Botet, M. Cella, and M. Colonna. 1996. Tyrosine phosphorylation of a human killer inhibitory receptor recruits protein tyrosine phosphatase 1C. J. Exp. Med. 184:93.
26. Fry, A. M., L. L. Lanier, and A. Weiss. 1996. Phosphotyrosines in the killer cell inhibitory receptor motif of NKB1 are required for negative signaling and for association with protein tyrosine phosphatase IC. J. Exp. Med. 184:295.
27. Burshtyn, D. N., A. M. Scharenberg, N. Wagtmann, S. Rajagopalan, K. Berrada, T. Yi, J.-P. Kinet, and E. O. Long. 1996. Recruitment of tyrosine phosphatase HCP by the killer cell inhibitory receptor. Immunity 4:77.
28. Binstadt, B. A., K. M. Brumbaugh, and P. J. Leibson. 1997. Signal transduction by human NK cell MHC-recognizing receptors. Immunol. Rev. 155:197.
29. Altin, J. G., and E. K. Sloan. 1997. The role of CD45 and CD45-associated molecules in T cell activation. Immunol. Cell Biol. 75:430.
30. Yamada, H., K. Kishihara, Y. Y. Kong, and K. Nomoto. 1996. Enhanced generation of NK cells with intact cytotoxic function in CD45 exon 6-deficient mice. J. Immunol. 157:1523.