메뉴 건너뛰기




Volumn 176, Issue 10, 2006, Pages 6302-6312

Proteasome inhibition to maximize the apoptotic potential of cytokine therapy for murine neuroblastoma tumors

Author keywords

[No Author keywords available]

Indexed keywords

BORTEZOMIB; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 2; PROTEASOME; PROTEASOME INHIBITOR; PROTEIN BID; PROTEIN KINASE B; TUMOR NECROSIS FACTOR ALPHA;

EID: 33646472266     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.176.10.6302     Document Type: Article
Times cited : (30)

References (58)
  • 3
    • 0032588320 scopus 로고    scopus 로고
    • Induction of apoptosis by IFN-γ in human neuroblastoma cell lines through the CD95/CD95L autocrine circuit
    • Bernassola, F., C. Scheuerpflug, I. Herr, P. H. Krammer, K. M. Debatin, and G. Melino. 1999. Induction of apoptosis by IFN-γ in human neuroblastoma cell lines through the CD95/CD95L autocrine circuit. Cell Death Differ. 6: 652-660.
    • (1999) Cell Death Differ. , vol.6 , pp. 652-660
    • Bernassola, F.1    Scheuerpflug, C.2    Herr, I.3    Krammer, P.H.4    Debatin, K.M.5    Melino, G.6
  • 4
    • 0037373901 scopus 로고    scopus 로고
    • Induction of caspase 8 by interferon-γ renders some neuroblastoma (NB) cells sensitive to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) but reveals that a lack of membrane TR1/TR2 also contributes to TRAIL resistance in NB
    • Yang, X., M. S. Merchant, M. E. Romero, M. Tsokos, L. H. Wexler, U. Kontny, C. L. Mackall, and C. J. Thiele. 2003. Induction of caspase 8 by interferon-γ renders some neuroblastoma (NB) cells sensitive to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) but reveals that a lack of membrane TR1/TR2 also contributes to TRAIL resistance in NB. Cancer Res. 63: 1122-1129.
    • (2003) Cancer Res. , vol.63 , pp. 1122-1129
    • Yang, X.1    Merchant, M.S.2    Romero, M.E.3    Tsokos, M.4    Wexler, L.H.5    Kontny, U.6    Mackall, C.L.7    Thiele, C.J.8
  • 5
    • 0035874993 scopus 로고    scopus 로고
    • Fas-mediated apoptosis in neuroblastoma requires mitochondrial activation and is inhibited by FLICE inhibitor protein and Bcl-2
    • Poulaki, V., N. Mitsiades, M. E. Romero, and M. Tsokos. 2001. Fas-mediated apoptosis in neuroblastoma requires mitochondrial activation and is inhibited by FLICE inhibitor protein and Bcl-2. Cancer Res. 61: 4864-4872.
    • (2001) Cancer Res. , vol.61 , pp. 4864-4872
    • Poulaki, V.1    Mitsiades, N.2    Romero, M.E.3    Tsokos, M.4
  • 6
    • 0035206272 scopus 로고    scopus 로고
    • The inhibitor of apoptosis protein survivin is associated with high-risk behavior of neuroblastoma
    • Azuhata, T., D. Scott, S. Takamizawa, J. Wen, A. Davidoff, M. Fukuzawa, and A. Sandler. 2001. The inhibitor of apoptosis protein survivin is associated with high-risk behavior of neuroblastoma. J. Pediatr. Surg. 36: 1785-1791.
    • (2001) J. Pediatr. Surg. , vol.36 , pp. 1785-1791
    • Azuhata, T.1    Scott, D.2    Takamizawa, S.3    Wen, J.4    Davidoff, A.5    Fukuzawa, M.6    Sandler, A.7
  • 7
    • 0037043603 scopus 로고    scopus 로고
    • Doxorubicin resistant neuroblastoma cells secrete factors that activate AKT and attenuate cytotoxicity in drug-sensitive cells
    • Emran, M. A., A. Rebbaa, and B. L. Mirkin. 2002. Doxorubicin resistant neuroblastoma cells secrete factors that activate AKT and attenuate cytotoxicity in drug-sensitive cells. Cancer Lett. 182: 53-59.
    • (2002) Cancer Lett. , vol.182 , pp. 53-59
    • Emran, M.A.1    Rebbaa, A.2    Mirkin, B.L.3
  • 8
    • 13244262655 scopus 로고    scopus 로고
    • Proteasome inhibitor PS-341 causes cell growth arrest and apoptosis in human glioblastoma multiforme (GBM)
    • Yin, D., H. Zhou, T. Kumagai, G. Liu, J. M. Ong, K. L. Black, and H. P. Koeffler. 2005. Proteasome inhibitor PS-341 causes cell growth arrest and apoptosis in human glioblastoma multiforme (GBM). Oncogene 24: 344-354.
    • (2005) Oncogene , vol.24 , pp. 344-354
    • Yin, D.1    Zhou, H.2    Kumagai, T.3    Liu, G.4    Ong, J.M.5    Black, K.L.6    Koeffler, H.P.7
  • 10
    • 2342667387 scopus 로고    scopus 로고
    • The development of proteasome inhibitors as anticancer drugs
    • Adams, J. 2004. The development of proteasome inhibitors as anticancer drugs. Cancer Cell 5: 417-421.
    • (2004) Cancer Cell , vol.5 , pp. 417-421
    • Adams, J.1
  • 11
    • 0035300479 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
    • Hideshima, T., P. Richardson, D. Chauhan, V. J. Palombella, P. J. Elliott, J. Adams, and K. C. Anderson. 2001. The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res. 61: 3071-3076.
    • (2001) Cancer Res. , vol.61 , pp. 3071-3076
    • Hideshima, T.1    Richardson, P.2    Chauhan, D.3    Palombella, V.J.4    Elliott, P.J.5    Adams, J.6    Anderson, K.C.7
  • 12
    • 0345447210 scopus 로고    scopus 로고
    • Velcade: U.S. FDA approval for the treatment of multiple myeloma progressing on prior therapy
    • Kane, R. C., P. F. Bross, A. T. Farrell, and R. Pazdur. 2003. Velcade: U.S. FDA approval for the treatment of multiple myeloma progressing on prior therapy. Oncologist 8: 508-513.
    • (2003) Oncologist , vol.8 , pp. 508-513
    • Kane, R.C.1    Bross, P.F.2    Farrell, A.T.3    Pazdur, R.4
  • 13
  • 14
    • 0032481131 scopus 로고    scopus 로고
    • Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of functional Bcl-2 and p53
    • Herrmann, J. L., F. Briones, Jr., S. Brisbay, C. J. Logothetis, and T. J. McDonnell. 1998. Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of functional Bcl-2 and p53. Oncogene 17: 2889-2899.
    • (1998) Oncogene , vol.17 , pp. 2889-2899
    • Herrmann, J.L.1    Briones Jr., F.2    Brisbay, S.3    Logothetis, C.J.4    McDonnell, T.J.5
  • 17
    • 0035328584 scopus 로고    scopus 로고
    • Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: Implications for systemic nuclear factor-κB inhibition
    • Cusack, J. C., Jr., R. Liu, M. Houston, K. Abendroth, P. J. Elliott, J. Adams, and A. S. Baldwin, Jr. 2001. Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: implications for systemic nuclear factor-κB inhibition. Cancer Res. 61: 3535-3540.
    • (2001) Cancer Res. , vol.61 , pp. 3535-3540
    • Cusack Jr., J.C.1    Liu, R.2    Houston, M.3    Abendroth, K.4    Elliott, P.J.5    Adams, J.6    Baldwin Jr., A.S.7
  • 18
    • 0033920566 scopus 로고    scopus 로고
    • Protease inhibitor-induced apoptosis: Accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition
    • An, W. G., S. G. Hwang, J. B. Trepel, and M. V. Blagosklonny. 2000. Protease inhibitor-induced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition. Leukemia 14: 1276-1283.
    • (2000) Leukemia , vol.14 , pp. 1276-1283
    • An, W.G.1    Hwang, S.G.2    Trepel, J.B.3    Blagosklonny, M.V.4
  • 22
    • 0034875305 scopus 로고    scopus 로고
    • Chemosensitization of pancreatic cancer by inhibition of the 26S proteasome
    • Bold, R. J., S. Virudachalam, and D. J. McConkey. 2001. Chemosensitization of pancreatic cancer by inhibition of the 26S proteasome. J. Surg. Res. 100: 11-17.
    • (2001) J. Surg. Res. , vol.100 , pp. 11-17
    • Bold, R.J.1    Virudachalam, S.2    McConkey, D.J.3
  • 24
    • 3142554015 scopus 로고    scopus 로고
    • Bortezomib and flavopiridol interact synergistically to induce apoptosis in chronic myeloid leukemia cells resistant to imatinib mesylate through both Bcr/Ab1-dependent and -independent mechanisms
    • Dai, Y., M. Rahmani, X. Y. Pei, P. Dent, and S. Grant. 2004. Bortezomib and flavopiridol interact synergistically to induce apoptosis in chronic myeloid leukemia cells resistant to imatinib mesylate through both Bcr/Ab1-dependent and -independent mechanisms. Blood 104: 509-518.
    • (2004) Blood , vol.104 , pp. 509-518
    • Dai, Y.1    Rahmani, M.2    Pei, X.Y.3    Dent, P.4    Grant, S.5
  • 25
    • 0032555716 scopus 로고    scopus 로고
    • Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
    • Luo, X., I. Budihardjo, H. Zou, C. Slaughter, and X. Wang. 1998. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94: 481-490.
    • (1998) Cell , vol.94 , pp. 481-490
    • Luo, X.1    Budihardjo, I.2    Zou, H.3    Slaughter, C.4    Wang, X.5
  • 27
    • 0027390602 scopus 로고
    • A novel interferon-inducible domain: Structural and functional analysis of the human interferon regulatory factor 1 gene promoter
    • Sims, S. H., Y. Cha, M. F. Romine, P. Q. Gao, K. Gottlieb, and A. B. Deisseroth. 1993. A novel interferon-inducible domain: structural and functional analysis of the human interferon regulatory factor 1 gene promoter. Mol. Cell Biol. 13: 690-702.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 690-702
    • Sims, S.H.1    Cha, Y.2    Romine, M.F.3    Gao, P.Q.4    Gottlieb, K.5    Deisseroth, A.B.6
  • 31
    • 0035815649 scopus 로고    scopus 로고
    • Elevated AKT activity protects the prostate cancer cell line LNCaP from TRAIL-induced apoptosis
    • Nesterov, A., X. Lu, M. Johnson, G. J. Miller, Y. Ivashchenko, and A. S. Kraft. 2001. Elevated AKT activity protects the prostate cancer cell line LNCaP from TRAIL-induced apoptosis. J. Biol. Chem. 276: 10767-10774.
    • (2001) J. Biol. Chem. , vol.276 , pp. 10767-10774
    • Nesterov, A.1    Lu, X.2    Johnson, M.3    Miller, G.J.4    Ivashchenko, Y.5    Kraft, A.S.6
  • 33
    • 0035947569 scopus 로고    scopus 로고
    • Interferon-γ sensitizes human myeloid leukemia cells to death receptor-mediated apoptosis by a pleiotropic mechanism
    • Varela, N., C. Munoz-Pinedo, C. Ruiz-Ruiz, G. Robledo, M. Pedroso, and A. Lopez-Rivas. 2001. Interferon-γ sensitizes human myeloid leukemia cells to death receptor-mediated apoptosis by a pleiotropic mechanism. J. Biol. Chem. 276: 17779-17787.
    • (2001) J. Biol. Chem. , vol.276 , pp. 17779-17787
    • Varela, N.1    Munoz-Pinedo, C.2    Ruiz-Ruiz, C.3    Robledo, G.4    Pedroso, M.5    Lopez-Rivas, A.6
  • 34
    • 84889271499 scopus 로고    scopus 로고
    • IFN-γ sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway
    • Fulda, S., and K. M. Debatin. 2002. IFN-γ sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway. Oncogene 21: 2295-2308.
    • (2002) Oncogene , vol.21 , pp. 2295-2308
    • Fulda, S.1    Debatin, K.M.2
  • 35
    • 0023685684 scopus 로고
    • Molecular cloning and expression of the human interferon-γ receptor
    • Aguet, M., Z. Dembic, and G. Merlin, 1988. Molecular cloning and expression of the human interferon-γ receptor. Cell 55: 273-280.
    • (1988) Cell , vol.55 , pp. 273-280
    • Aguet, M.1    Dembic, Z.2    Merlin, G.3
  • 37
    • 0036889113 scopus 로고    scopus 로고
    • The role of IFN-γ in immune responses to viral infections of the central nervous system
    • Chesler, D. A., and C. S. Reiss. 2002. The role of IFN-γ in immune responses to viral infections of the central nervous system. Cytokine Growth Factor Rev. 13: 441-454.
    • (2002) Cytokine Growth Factor Rev. , vol.13 , pp. 441-454
    • Chesler, D.A.1    Reiss, C.S.2
  • 38
    • 0027125522 scopus 로고
    • FDA panel backs interleukin-2
    • Culliton, B. J. 1992. FDA panel backs interleukin-2. Nature 355: 287.
    • (1992) Nature , vol.355 , pp. 287
    • Culliton, B.J.1
  • 40
    • 0022355854 scopus 로고
    • Phase II results with recombinant interferons: Renal cell carcinoma and malignant melanoma
    • Kuzmits, R., E. M. Kokoschka, M. Micksche, H. Ludwig, and R. Flener. 1985. Phase II results with recombinant interferons: renal cell carcinoma and malignant melanoma. Oncology 42(Suppl. 1): 26-32.
    • (1985) Oncology , vol.42 , Issue.SUPPL. 1 , pp. 26-32
    • Kuzmits, R.1    Kokoschka, E.M.2    Micksche, M.3    Ludwig, H.4    Flener, R.5
  • 41
    • 0034103809 scopus 로고    scopus 로고
    • Phase I trial of twice-weekly intravenous interleukin 12 in patients with metastatic renal cell cancer or malignant melanoma: Ability to maintain IFN-γ induction is associated with clinical response
    • Gollob, J. A., J. W. Mier, K. Veenstra, D. F. McDermott, D. Clancy, M. Clancy, and M. B. Atkins. 2000. Phase I trial of twice-weekly intravenous interleukin 12 in patients with metastatic renal cell cancer or malignant melanoma: ability to maintain IFN-γ induction is associated with clinical response. Clin. Cancer Res. 6: 1678-1692.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 1678-1692
    • Gollob, J.A.1    Mier, J.W.2    Veenstra, K.3    McDermott, D.F.4    Clancy, D.5    Clancy, M.6    Atkins, M.B.7
  • 43
    • 27744482893 scopus 로고    scopus 로고
    • Tolerabilily and antitumor activity of recombinant human IL-18 (rhIL-18) administered as five daily intravenous infusions in patients with solid tumors
    • Robertson, M. J., J. Mier, T. Logan, H. Koon, J. Weisenbach, S. Roberts, C. Oei, L. Kirby, S. Kathman, and L. Pandite. 2004. Tolerabilily and antitumor activity of recombinant human IL-18 (rhIL-18) administered as five daily intravenous infusions in patients with solid tumors. J. Clin. Oncol. 22: 2553.
    • (2004) J. Clin. Oncol. , vol.22 , pp. 2553
    • Robertson, M.J.1    Mier, J.2    Logan, T.3    Koon, H.4    Weisenbach, J.5    Roberts, S.6    Oei, C.7    Kirby, L.8    Kathman, S.9    Pandite, L.10
  • 44
    • 0021837706 scopus 로고
    • Regression of established pulmonary metastases and subcutaneous tumor mediated by the systemic administration of high-dose recombinant interleukin 2
    • Rosenberg, S. A., J. J. Mule, P. J. Spiess, C. M. Reichert, and S. L. Schwartz. 1985. Regression of established pulmonary metastases and subcutaneous tumor mediated by the systemic administration of high-dose recombinant interleukin 2. J. Exp. Med. 161: 1169-1188.
    • (1985) J. Exp. Med. , vol.161 , pp. 1169-1188
    • Rosenberg, S.A.1    Mule, J.J.2    Spiess, P.J.3    Reichert, C.M.4    Schwartz, S.L.5
  • 46
    • 0030067276 scopus 로고    scopus 로고
    • Administration of interleukin 12 with pulse interleukin 2 and the rapid and complete eradication of murine renal carcinoma
    • Wigginton, J. M., K. L. Komschlies, T. C. Back, J. L. Franco, M. J. Brunda, and R. H. Wiltrout. 1996. Administration of interleukin 12 with pulse interleukin 2 and the rapid and complete eradication of murine renal carcinoma. J. Natl. Cancer Inst. 88: 38-43.
    • (1996) J. Natl. Cancer Inst. , vol.88 , pp. 38-43
    • Wigginton, J.M.1    Komschlies, K.L.2    Back, T.C.3    Franco, J.L.4    Brunda, M.J.5    Wiltrout, R.H.6
  • 47
    • 0037108519 scopus 로고    scopus 로고
    • Synergistic engagement of an ineffective endogenous antitumor immune response and induction of IFN-γ and FAS-ligand-dependent tumor eradication by combined administration of IL-18 and IL-2
    • Wigginton, J. M., J.-K. Lee, T. A. Wiltrout, W. G. Alvord, J. A. Hixon, J. Subleski, T. C. Back, and R. H. Wiltrout. 2002. Synergistic engagement of an ineffective endogenous antitumor immune response and induction of IFN-γ and FAS-ligand-dependent tumor eradication by combined administration of IL-18 and IL-2. J. Immunol 169: 4467-4474.
    • (2002) J. Immunol. , vol.169 , pp. 4467-4474
    • Wigginton, J.M.1    Lee, J.-K.2    Wiltrout, T.A.3    Alvord, W.G.4    Hixon, J.A.5    Subleski, J.6    Back, T.C.7    Wiltrout, R.H.8
  • 51
    • 0032532283 scopus 로고    scopus 로고
    • Molecular mechanisms of immune-mediated lysis of murine renal cancer: Differential contributions of perforin-dependent versus Fas-mediated pathways in lysis by NK and T cells
    • Sayers, T. J., A. D. Brooks, J. K. Lee, R. G. Fenton, K. L. Komschlies, J. M. Wigginton, R. Winkler-Pickett, and R. H. Wiltrout. 1998. Molecular mechanisms of immune-mediated lysis of murine renal cancer: differential contributions of perforin-dependent versus Fas-mediated pathways in lysis by NK and T cells. J. Immunol 161: 3957-3965.
    • (1998) J. Immunol. , vol.161 , pp. 3957-3965
    • Sayers, T.J.1    Brooks, A.D.2    Lee, J.K.3    Fenton, R.G.4    Komschlies, K.L.5    Wigginton, J.M.6    Winkler-Pickett, R.7    Wiltrout, R.H.8
  • 53
    • 0035911242 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to Interferon γ-dependent natural killer cell protection from tumor metastasis
    • Smyth, M. J., E. Cretney, K. Takeda, R. H. Wiltrout, L. M. Sedger, N. Kayagaki, H. Yagita, and K. Okumura. 2001. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to Interferon γ-dependent natural killer cell protection from tumor metastasis. J. Exp. Med. 193: 661-670.
    • (2001) J. Exp. Med. , vol.193 , pp. 661-670
    • Smyth, M.J.1    Cretney, E.2    Takeda, K.3    Wiltrout, R.H.4    Sedger, L.M.5    Kayagaki, N.6    Yagita, H.7    Okumura, K.8
  • 55
    • 0034647563 scopus 로고    scopus 로고
    • Ubiquitin-mediated degradation of the proapoptotic active form of bid: A functional consequence on apoptosis induction
    • Breitschopf, K., A. M. Zeiher, and S. Dimmeler. 2000. Ubiquitin-mediated degradation of the proapoptotic active form of bid: a functional consequence on apoptosis induction. J. Biol. Chem. 275: 21648-21652.
    • (2000) J. Biol. Chem. , vol.275 , pp. 21648-21652
    • Breitschopf, K.1    Zeiher, A.M.2    Dimmeler, S.3
  • 56
    • 0642349188 scopus 로고    scopus 로고
    • Differential effects of the proteasome inhibitor bortezomib on apoptosis and angiogenesis in human prostate tumor xenografts
    • Williams, S., C. Pettaway, R. Song, C. Papandreou, C. Logothetis, and D. J. McConkey. 2003. Differential effects of the proteasome inhibitor bortezomib on apoptosis and angiogenesis in human prostate tumor xenografts. Mol. Cancer Ther. 1: 835-843.
    • (2003) Mol. Cancer Ther. , vol.1 , pp. 835-843
    • Williams, S.1    Pettaway, C.2    Song, R.3    Papandreou, C.4    Logothetis, C.5    McConkey, D.J.6
  • 57
    • 16544389047 scopus 로고    scopus 로고
    • Phase I study of the proteasome inhibitor bortezomib in pediatric patients with refractory solid tumors: A Children's Oncology Group study (ADVL0015)
    • Blaney, S. M., M. Bernstein, K. Neville, J. Ginsberg, B. Kitchen, T. Horton, S. L. Berg, M. Krailo, and P. C. Adamson. 2004. Phase I study of the proteasome inhibitor bortezomib in pediatric patients with refractory solid tumors: a Children's Oncology Group study (ADVL0015). J. Clin. Oncol. 22: 4752-4757.
    • (2004) J. Clin. Oncol. , vol.22 , pp. 4752-4757
    • Blaney, S.M.1    Bernstein, M.2    Neville, K.3    Ginsberg, J.4    Kitchen, B.5    Horton, T.6    Berg, S.L.7    Krailo, M.8    Adamson, P.C.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.