-
1
-
-
0029807944
-
How proteolysis drives the cell cycle
-
King R, Deshaies R, Peters J-M, et al: How proteolysis drives the cell cycle. Science 274: 1652-1659, 1996
-
(1996)
Science
, vol.274
, pp. 1652-1659
-
-
King, R.1
Deshaies, R.2
Peters, J.-M.3
-
2
-
-
0036181371
-
Development of the proteasome inhibitor, PS-341
-
Adams J, Boyd M: Development of the proteasome inhibitor, PS-341. Oncologist 7:9-16, 2002
-
(2002)
Oncologist
, vol.7
, pp. 9-16
-
-
Adams, J.1
Boyd, M.2
-
3
-
-
0028180516
-
A beta-lactone related to lactacystin induces neurite outgrowth in a neuroblastoma cell line and inhibits cell cycle progression in an osteosarcoma cell line
-
Fenteany G, Standaert R, Reichard G, et al: A beta-lactone related to lactacystin induces neurite outgrowth in a neuroblastoma cell line and inhibits cell cycle progression in an osteosarcoma cell line. Proc Natl Acad Sci U S A 91:3358-3362, 1994
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 3358-3362
-
-
Fenteany, G.1
Standaert, R.2
Reichard, G.3
-
4
-
-
0026011974
-
Structure of lactacystin, a new microbial metabolite which induces differentiation of neuroblastoma cells
-
Omura S, Matsuzaki K, Fujimoto T: Structure of lactacystin, a new microbial metabolite which induces differentiation of neuroblastoma cells. J Antibiot 44:117-118, 1991
-
(1991)
J Antibiot
, vol.44
, pp. 117-118
-
-
Omura, S.1
Matsuzaki, K.2
Fujimoto, T.3
-
5
-
-
0033068608
-
The involvement of proteasome in myogenic differentiation of murine myocytes and human rhabdomyosarcoma cells
-
Mugita N, Honda Y, Nakamura H: The involvement of proteasome in myogenic differentiation of murine myocytes and human rhabdomyosarcoma cells. Int J Mol Med 3:127-137, 1999
-
(1999)
Int J Mol Med
, vol.3
, pp. 127-137
-
-
Mugita, N.1
Honda, Y.2
Nakamura, H.3
-
6
-
-
0030869925
-
Apoptosis of Ewing's sarcoma cells is accompanied by accumulation of ubiquitinated proteins
-
Soldatenkov V, Dritschilo A: Apoptosis of Ewing's sarcoma cells is accompanied by accumulation of ubiquitinated proteins. Cancer Res 57:3881-3885, 1997
-
(1997)
Cancer Res
, vol.57
, pp. 3881-3885
-
-
Soldatenkov, V.1
Dritschilo, A.2
-
7
-
-
0033152760
-
Proteasome inhibitors: A novel class of potent and effective antitumor agents
-
Adams J, Palombella V, Sausville E, et al: Proteasome inhibitors: A novel class of potent and effective antitumor agents. Cancer Res 59: 2615-2622, 1999
-
(1999)
Cancer Res
, vol.59
, pp. 2615-2622
-
-
Adams, J.1
Palombella, V.2
Sausville, E.3
-
8
-
-
0037111832
-
Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies
-
Orlowski R, Stinchcombe T, Mitchell B, et al: Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies. J Clin Oncol 20:4420-4427, 2002
-
(2002)
J Clin Oncol
, vol.20
, pp. 4420-4427
-
-
Orlowski, R.1
Stinchcombe, T.2
Mitchell, B.3
-
9
-
-
0036023407
-
A phase I trial of the novel proteasome inhibitor PS341 in advanced solid tumor malignancies
-
Aghajanian C, Soignet S, Dizon DS, et al: A phase I trial of the novel proteasome inhibitor PS341 in advanced solid tumor malignancies. Clin Cancer Res 8:2505-2511, 2002
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2505-2511
-
-
Aghajanian, C.1
Soignet, S.2
Dizon, D.S.3
-
10
-
-
0037973279
-
A phase 2 study of bortezomib in relapsed, refractory myeloma
-
Richardson P, Barlogie B, Berenson J, et al: A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Med 348:2609-2617, 2003
-
(2003)
N Engl J Med
, vol.348
, pp. 2609-2617
-
-
Richardson, P.1
Barlogie, B.2
Berenson, J.3
-
11
-
-
0034037622
-
Proteasome inhibition measurements: Clinical applications
-
Lightcap ES, McCormack TA, Pien C, et al: Proteasome inhibition measurements: Clinical applications. Clin Chem 46:673-683, 2000
-
(2000)
Clin Chem
, vol.46
, pp. 673-683
-
-
Lightcap, E.S.1
McCormack, T.A.2
Pien, C.3
-
12
-
-
0032885416
-
The proteasome inhibitor PS-341 in cancer therapy
-
Teicher B, Ara G, Herbst R, et al: The proteasome inhibitor PS-341 in cancer therapy. Clin Cancer Res 5:2368-2645, 1999
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2368-2645
-
-
Teicher, B.1
Ara, G.2
Herbst, R.3
-
13
-
-
0035300479
-
The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
-
Hideshima T, Richardson P, Chauhan D, et al: The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res 61:3071-3076, 2001
-
(2001)
Cancer Res
, vol.61
, pp. 3071-3076
-
-
Hideshima, T.1
Richardson, P.2
Chauhan, D.3
-
14
-
-
0037443551
-
The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: Therapeutic applications
-
Mitsiades N, Mitsiades C, Richardson P, et al: The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: Therapeutic applications. Blood 101:2377-2380, 2002
-
(2002)
Blood
, vol.101
, pp. 2377-2380
-
-
Mitsiades, N.1
Mitsiades, C.2
Richardson, P.3
-
15
-
-
0035328584
-
Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: Implications for systemic nuclear factor-kappa B inhibition
-
Cusack J Jr, Liu R, Houston M, et al: Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: implications for systemic nuclear factor-kappa B inhibition. Cancer Res 61:3535-3540, 2001
-
(2001)
Cancer Res
, vol.61
, pp. 3535-3540
-
-
Cusack Jr., J.1
Liu, R.2
Houston, M.3
-
16
-
-
0034981649
-
26S proteasome inhibition induces apoptosis and limits growth of human pancreatic cancer
-
Shah S, Potter M, McDade T, et al: 26S proteasome inhibition induces apoptosis and limits growth of human pancreatic cancer. J Cell Biochem 82:110-122, 2001
-
(2001)
J Cell Biochem
, vol.82
, pp. 110-122
-
-
Shah, S.1
Potter, M.2
McDade, T.3
-
17
-
-
0034875305
-
Chemosensitization of pancreatic cancer by inhibition of the 26S proteasome
-
Bold R, Virudachalam S, McConkey D: Chemosensitization of pancreatic cancer by inhibition of the 26S proteasome. J Surg Res 100: 11-17, 2001
-
(2001)
J Surg Res
, vol.100
, pp. 11-17
-
-
Bold, R.1
Virudachalam, S.2
McConkey, D.3
-
18
-
-
0038240386
-
The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP
-
Sayers T, Brooks A, Koh C, et al: The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP. Blood 102:303-310, 2003
-
(2003)
Blood
, vol.102
, pp. 303-310
-
-
Sayers, T.1
Brooks, A.2
Koh, C.3
-
19
-
-
84871472905
-
Geldanamycin combined with PS-341 synergistically activates a cellular stress response, causes massive accumulation of ubiquitinated proteins and shows enhanced antitumor activity
-
abstr 785
-
Mimnaugh E, Xu W, Isaacs J, et al: Geldanamycin combined with PS-341 synergistically activates a cellular stress response, causes massive accumulation of ubiquitinated proteins and shows enhanced antitumor activity. Proc Am Assoc Cancer Res 43:179, 2003 (abstr 785)
-
(2003)
Proc Am Assoc Cancer Res
, vol.43
, pp. 179
-
-
Mimnaugh, E.1
Xu, W.2
Isaacs, J.3
-
20
-
-
84871470739
-
Hsp90 inhibitors prolong survival in a SCID/NOD mouse model of diffuse multiple myeloma: Therapeutic implications
-
abstr 788
-
Mitsiades C, Mitsiades N, Poulaki V, et al: Hsp90 inhibitors prolong survival in a SCID/NOD mouse model of diffuse multiple myeloma: Therapeutic implications. Proc Am Assoc Cancer Res 43:180, 2003 (abstr 788)
-
(2003)
Proc Am Assoc Cancer Res
, vol.43
, pp. 180
-
-
Mitsiades, C.1
Mitsiades, N.2
Poulaki, V.3
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