Independent contributions of GR-1+ leukocytes and Fas/Fasl interactions to induce apoptosis following interleukin-12 gene therapy in a metastatic model of prostate cancer

Human Gene Therapy

Volumn 12, Issue 12, 2001, Pages 1485-1498

  Sanford, Michael A ^a   Yan, Ying ^a   Canfield, Steven E ^a   Hassan, Waleed ^a   Selleck, William A ^a   Atkinson, Gertrude ^a   Chen, Shu Hsia ^a   Hall, Simon J ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE INHIBITOR; FAS ANTIGEN; FAS LIGAND; GAMMA INTERFERON; INTERLEUKIN 12;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CANCER MODEL; CANCER SURVIVAL; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DOSE CALCULATION; DRUG MECHANISM; EXPERIMENTAL NEOPLASM; LUNG METASTASIS; LYMPHOCYTE COUNT; METASTASIS INHIBITION; MOUSE; NATURAL KILLER CELL; NEUTROPHIL; NONHUMAN; PROSTATE CARCINOMA; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TUMOR ASSOCIATED LEUKOCYTE;

ADENOVIRIDAE; ANIMALS; ANTIGENS, CD95; APOPTOSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; FAS LIGAND PROTEIN; GENE THERAPY; IMMUNOHISTOCHEMISTRY; INTERFERON TYPE II; INTERLEUKIN-12; KILLER CELLS, NATURAL; LYMPHOCYTES, TUMOR-INFILTRATING; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; NECROSIS; NEOPLASM METASTASIS; NEUTROPHILS; PROSTATIC NEOPLASMS; TIME FACTORS; TUMOR CELLS, CULTURED; UP-REGULATION;

ADENOVIRIDAE; ANIMALIA;

EID: 0035574745     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/10430340152480221     Document Type: Article

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