Conformational changes associated with receptor-stimulated guanine nucleotide exchange in a heterotrimeric G-protein α-subunit: NMR analysis of GTPγS-bound states

Journal of Biological Chemistry

Volumn 281, Issue 11, 2006, Pages 7635-7648

  Ridge, Kevin D ^a   Abdulaev, Najmoutin G ^b   Zhang, Cheng ^a   Ngo, Tony ^a   Brabazon, Danielle M ^c   Marino, John P ^b  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^c LOYOLA UNIVERSITY MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEAR MAGNETIC RESONANCE; PHOSPHATES; QUANTUM THEORY;

CHIMERA; HETEROTRIMERS; NUCLEOTIDES;

PROTEINS;

G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE EXCHANGE FACTOR; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; MAGNESIUM ION; RHODOPSIN; DETERGENT; GUANINE; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); HYBRID PROTEIN; MAGNESIUM; METARHODOPSINS; OPSIN; SUBTILISIN;

ARTICLE; CONFORMATIONAL TRANSITION; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; AMINO ACID SEQUENCE; ANIMAL; BIOLOGICAL MODEL; CATALYSIS; CATTLE; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; CYTOPLASM; DIMERIZATION; IMMUNOPRECIPITATION; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING; TIME; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; CATALYSIS; CATTLE; CRYSTALLOGRAPHY, X-RAY; CYTOPLASM; DETERGENTS; DIMERIZATION; GUANINE; GUANINE NUCLEOTIDE EXCHANGE FACTORS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); IMMUNOPRECIPITATION; MAGNESIUM; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; OPSIN; PROTEIN BINDING; PROTEIN CONFORMATION; RECOMBINANT FUSION PROTEINS; RHODOPSIN; SUBTILISIN; TIME FACTORS;

EID: 33646379375     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M509851200     Document Type: Article

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