Conformational changes in the amino-terminal helix of the G protein αi1 following dissociation from gβγ subunit and activation

Biochemistry

Volumn 41, Issue 31, 2002, Pages 9962-9972

  Medkova, Martina ^a   Preininger, Anita M ^a   Yu, Nan Jun ^c   Hubbell, Wayne L ^c   Hamm, Heidi E ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TERMINAL HELIX;

CATALYSIS; CRYSTAL STRUCTURE; FLUORESCENCE; HYDROPHOBICITY; MUTAGENESIS;

PROTEINS;

ALUMINUM DERIVATIVE; CYSTEINE; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATE; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; LUCIFER YELLOW; MUTANT PROTEIN; PROTEIN SUBUNIT;

ALPHA CHAIN; ALPHA HELIX; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BETA CHAIN; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISSOCIATION; FLUORESCENCE; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN FOLDING; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; SOLVATION; SPIN LABELING;

BASE SEQUENCE; CYSTEINE; DNA PRIMERS; ELECTRON SPIN RESONANCE SPECTROSCOPY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLUORESCENT DYES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 0037031315     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0255726     Document Type: Article

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