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Volumn 84, Issue 3, 2006, Pages 318-330

Reverse immunology approach for the identification of CD8 T-cell-defined antigens: Advantages and hurdles

Author keywords

Cytolytic T lymphocyte (CTL); Immunotherapy; Tumour antigen

Indexed keywords

CD8 ANTIGEN; GENE PRODUCT; HLA ANTIGEN; PROTEASOME; TUMOR ANTIGEN;

EID: 33646119668     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1111/j.1440-1711.2006.01447.x     Document Type: Review
Times cited : (32)

References (165)
  • 1
    • 0014932541 scopus 로고
    • In vitro cytotoxic activity of thymus cells sensitized to alloantigens
    • Cerottini JC Nordin AA Brunner KT. In vitro cytotoxic activity of thymus cells sensitized to alloantigens. Nature 1970 227 72 3.
    • (1970) Nature , vol.227 , pp. 72-3
    • Cerottini, J.C.1    Nordin, A.A.2    Brunner, K.T.3
  • 2
    • 0014964069 scopus 로고
    • Specific in vitro cytotoxicity of thymus-derived lymphocytes sensitized to alloantigens
    • Cerottini JC Nordin AA Brunner KT. Specific in vitro cytotoxicity of thymus-derived lymphocytes sensitized to alloantigens. Nature 1970 228 1308 309.
    • (1970) Nature , vol.228 , pp. 1308-309
    • Cerottini, J.C.1    Nordin, A.A.2    Brunner, K.T.3
  • 3
    • 0016345568 scopus 로고
    • Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system
    • Zinkernagel RM Doherty PC. Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system. Nature 1974 248 701 702.
    • (1974) Nature , vol.248 , pp. 701-702
    • Zinkernagel, R.M.1    Doherty, P.C.2
  • 4
    • 0016181550 scopus 로고
    • Restriction by H-2 gene complex of transfer of cell-mediated immunity to Listeria monocytogenes
    • Zinkernagel RM. Restriction by H-2 gene complex of transfer of cell-mediated immunity to Listeria monocytogenes. Nature 1974 251 230 33.
    • (1974) Nature , vol.251 , pp. 230-33
    • Zinkernagel, R.M.1
  • 6
    • 0023187442 scopus 로고
    • The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens
    • Bjorkman PJ Saper MA Samraoui B Bennett WS Strominger JL Wiley DC. The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens. Nature 1987 329 512 18.
    • (1987) Nature , vol.329 , pp. 512-18
    • Bjorkman, P.J.1    Saper, M.A.2    Samraoui, B.3    Bennett, W.S.4    Strominger, J.L.5    Wiley, D.C.6
  • 7
    • 0021162031 scopus 로고
    • Genomic organization and sequence of T-cell receptor beta-chain constant- and joining-region genes
    • Gascoigne NR Chien Y Becker DM Kavaler J Davis MM. Genomic organization and sequence of T-cell receptor beta-chain constant- and joining-region genes. Nature 1984 310 387 91.
    • (1984) Nature , vol.310 , pp. 387-91
    • Gascoigne, N.R.1    Chien, Y.2    Becker, D.M.3    Kavaler, J.4    Davis, M.M.5
  • 8
    • 0021228184 scopus 로고
    • Structure, expression and divergence of T-cell receptor beta-chain variable regions
    • Patten P Yokota T Rothbard J Chien Y Arai K Davis MM. Structure, expression and divergence of T-cell receptor beta-chain variable regions. Nature 1984 312 40 46.
    • (1984) Nature , vol.312 , pp. 40-46
    • Patten, P.1    Yokota, T.2    Rothbard, J.3    Chien, Y.4    Arai, K.5    Davis, M.M.6
  • 9
    • 0021196170 scopus 로고
    • A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains
    • Yanagi Y Yoshikai Y Leggett K Clark SP Aleksander I Mak TW. A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains. Nature 1984 308 145 9.
    • (1984) Nature , vol.308 , pp. 145-9
    • Yanagi, Y.1    Yoshikai, Y.2    Leggett, K.3    Clark, S.P.4    Aleksander, I.5    Mak, T.W.6
  • 10
    • 0021711727 scopus 로고
    • Sequence and expression of transcripts of the human T-cell receptor beta-chain genes
    • Yoshikai Y Anatoniou D Clark SP et al. Sequence and expression of transcripts of the human T-cell receptor beta-chain genes. Nature 1984 312 521 4.
    • (1984) Nature , vol.312 , pp. 521-4
    • Yoshikai, Y.1    Anatoniou, D.2    Clark, S.P.3
  • 11
    • 0025855156 scopus 로고
    • Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules
    • Falk K Rotzschke O Stevanovic S Jung G Rammensee HG. Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature 1991 351 290 96.
    • (1991) Nature , vol.351 , pp. 290-96
    • Falk, K.1    Rotzschke, O.2    Stevanovic, S.3    Jung, G.4    Rammensee, H.G.5
  • 12
    • 0027304399 scopus 로고
    • Prominent role of secondary anchor residues in peptide binding to HLA-A2.1 molecules
    • Ruppert J Sidney J Celis E Kubo RT Grey HM Sette A. Prominent role of secondary anchor residues in peptide binding to HLA-A2.1 molecules. Cell 1993 74 929 37.
    • (1993) Cell , vol.74 , pp. 929-37
    • Ruppert, J.1    Sidney, J.2    Celis, E.3    Kubo, R.T.4    Grey, H.M.5    Sette, A.6
  • 14
    • 3142541510 scopus 로고
    • T-cell-mediated cytotoxicity against autologous malignant melanoma: Analysis with interleukin 2-dependent T-cell cultures
    • Knuth A Danowski B Oettgen HF Old LJ. T-cell-mediated cytotoxicity against autologous malignant melanoma: analysis with interleukin 2-dependent T-cell cultures. Proc. Natl Acad. Sci. USA 1984 81 3511 15.
    • (1984) Proc. Natl Acad. Sci. USA , vol.81 , pp. 3511-15
    • Knuth, A.1    Danowski, B.2    Oettgen, H.F.3    Old, L.J.4
  • 15
    • 0026322151 scopus 로고
    • A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma
    • van der Bruggen P Traversari C Chomez P et al. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science 1991 254 1643 7.
    • (1991) Science , vol.254 , pp. 1643-7
    • Van Der Bruggen, P.1    Traversari, C.2    Chomez, P.3
  • 16
    • 0029798212 scopus 로고    scopus 로고
    • Renal-cell carcinoma-specific lysis by cytotoxic T-lymphocyte clones isolated from peripheral blood lymphocytes and tumor-infiltrating lymphocytes
    • Brouwenstijn N Gaugler B Kruse KM et al. Renal-cell carcinoma-specific lysis by cytotoxic T-lymphocyte clones isolated from peripheral blood lymphocytes and tumor-infiltrating lymphocytes. Int. J. Cancer 1996 68 177 82.
    • (1996) Int. J. Cancer , vol.68 , pp. 177-82
    • Brouwenstijn, N.1    Gaugler, B.2    Kruse, K.M.3
  • 17
    • 0035872398 scopus 로고    scopus 로고
    • A point mutation in the alpha-actinin-4 gene generates an antigenic peptide recognized by autologous cytolytic T lymphocytes on a human lung carcinoma
    • Echchakir H Mami-Chouaib F Vergnon I et al. A point mutation in the alpha-actinin-4 gene generates an antigenic peptide recognized by autologous cytolytic T lymphocytes on a human lung carcinoma. Cancer Res. 2001 61 4078 83.
    • (2001) Cancer Res , vol.61 , pp. 4078-83
    • Echchakir, H.1    Mami-Chouaib, F.2    Vergnon, I.3
  • 18
    • 0032186274 scopus 로고    scopus 로고
    • A breast and melanoma-shared tumor antigen: T cell responses to antigenic peptides translated from different open reading frames
    • Wang RF Johnston SL Zeng G Topalian SL Schwartzentruber DJ Rosenberg SA. A breast and melanoma-shared tumor antigen: T cell responses to antigenic peptides translated from different open reading frames. J. Immunol. 1998 161 3598 606.
    • (1998) J. Immunol , vol.161 , pp. 3598-606
    • Wang, R.F.1    Johnston, S.L.2    Zeng, G.3    Topalian, S.L.4    Schwartzentruber, D.J.5    Rosenberg, S.A.6
  • 19
    • 3042722266 scopus 로고    scopus 로고
    • Immunotherapy: Bewitched, bothered, and bewildered no more
    • Steinman RM Mellman I. Immunotherapy: bewitched, bothered, and bewildered no more. Science 2004 305 197 200.
    • (2004) Science , vol.305 , pp. 197-200
    • Steinman, R.M.1    Mellman, I.2
  • 20
    • 0042839761 scopus 로고    scopus 로고
    • Antigen-specific immunotherapy and cancer vaccines
    • Jager E Jager D Knuth A. Antigen-specific immunotherapy and cancer vaccines. Int. J. Cancer 2003 106 817 20.
    • (2003) Int. J. Cancer , vol.106 , pp. 817-20
    • Jager, E.1    Jager, D.2    Knuth, A.3
  • 21
    • 3042844293 scopus 로고    scopus 로고
    • Cancer immunotherapy: A treatment for the masses
    • Blattman JN Greenberg PD. Cancer immunotherapy: a treatment for the masses. Science 2004 305 200 205.
    • (2004) Science , vol.305 , pp. 200-205
    • Blattman, J.N.1    Greenberg, P.D.2
  • 22
    • 0037137530 scopus 로고    scopus 로고
    • Therapeutic cancer vaccines based on molecularly defined human tumor antigens
    • Romero P Pittet M Dutoit V et al. Therapeutic cancer vaccines based on molecularly defined human tumor antigens. Vaccine 2002 20 Suppl. 4 A2 A7.
    • (2002) Vaccine , vol.20 , Issue.SUPPL. 4
    • Romero, P.1    Pittet, M.2    Dutoit, V.3
  • 23
    • 0742304314 scopus 로고    scopus 로고
    • Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor-specific T cells
    • Speiser DE Pittet MJ Rimoldi D et al. Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor-specific T cells. Semin. Cancer Biol. 2003 13 461 72.
    • (2003) Semin. Cancer Biol , vol.13 , pp. 461-72
    • Speiser, D.E.1    Pittet, M.J.2    Rimoldi, D.3
  • 24
    • 4644253363 scopus 로고    scopus 로고
    • International meeting on cancer vaccines: How can we enhance efficacy of therapeutic vaccines?
    • Belardelli F Ferrantini M Parmiani G Schlom J Garaci E. International meeting on cancer vaccines: how can we enhance efficacy of therapeutic vaccines? Cancer Res. 2004 64 6827 30.
    • (2004) Cancer Res , vol.64 , pp. 6827-30
    • Belardelli, F.1    Ferrantini, M.2    Parmiani, G.3    Schlom, J.4    Garaci, E.5
  • 25
    • 0037312550 scopus 로고    scopus 로고
    • Vaccine-induced CD8+ T-cell responses to MAGE-3 correlate with clinical outcome in patients with melanoma
    • Reynolds SR Zeleniuch-Jacquotte A Shapiro RL et al. Vaccine-induced CD8+ T-cell responses to MAGE-3 correlate with clinical outcome in patients with melanoma. Clin. Cancer Res. 2003 9 657 62.
    • (2003) Clin. Cancer Res , vol.9 , pp. 657-62
    • Reynolds, S.R.1    Zeleniuch-Jacquotte, A.2    Shapiro, R.L.3
  • 26
    • 0028326159 scopus 로고
    • Induction of anti-tumor cytotoxic T lymphocytes in normal humans using primary cultures and synthetic peptide epitopes
    • Celis E Tsai V Crimi C et al. Induction of anti-tumor cytotoxic T lymphocytes in normal humans using primary cultures and synthetic peptide epitopes. Proc. Natl Acad. Sci. USA 1994 91 2105 9.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 2105-9
    • Celis, E.1    Tsai, V.2    Crimi, C.3
  • 27
    • 0029924107 scopus 로고    scopus 로고
    • Human tumor antigens recognized by T lymphocytes
    • Boon T van der Bruggen P. Human tumor antigens recognized by T lymphocytes. J. Exp. Med. 1996 183 725 9.
    • (1996) J. Exp. Med , vol.183 , pp. 725-9
    • Boon, T.1    Van Der Bruggen, P.2
  • 29
    • 0030858698 scopus 로고    scopus 로고
    • Characterization of antigenic peptide epitopes by reverse immunology: Induction of cytotoxic T lymphocytes specific for exogenous peptide only
    • Tanzarella S Fleischhauer K van Endert P Bordignon C Traversari C. Characterization of antigenic peptide epitopes by reverse immunology: induction of cytotoxic T lymphocytes specific for exogenous peptide only. Int. J. Cancer 1997 72 912 15.
    • (1997) Int. J. Cancer , vol.72 , pp. 912-15
    • Tanzarella, S.1    Fleischhauer, K.2    Van Endert, P.3    Bordignon, C.4    Traversari, C.5
  • 30
    • 1542357604 scopus 로고    scopus 로고
    • Identification of tumor antigens and T-cell epitopes, and its clinical application
    • Paschen A Eichmuller S Schadendorf D. Identification of tumor antigens and T-cell epitopes, and its clinical application. Cancer Immunol. Immunother. 2004 53 196 203.
    • (2004) Cancer Immunol. Immunother , vol.53 , pp. 196-203
    • Paschen, A.1    Eichmuller, S.2    Schadendorf, D.3
  • 31
    • 4444243096 scopus 로고    scopus 로고
    • Tumor-specific shared antigenic peptides recognized by human T cells
    • Van Der Bruggen P Zhang Y Chaux P et al. Tumor-specific shared antigenic peptides recognized by human T cells. Immunol. Rev. 2002 188 51 64.
    • (2002) Immunol. Rev , vol.188 , pp. 51-64
    • Van Der Bruggen, P.1    Zhang, Y.2    Chaux, P.3
  • 32
    • 18944387170 scopus 로고    scopus 로고
    • Identification and characterization of HIV-1-specific CD8+ T cell epitopes presented by HLA-A*2601
    • Satoh M Takamiya Y Oka S Tokunaga K Takiguchi M. Identification and characterization of HIV-1-specific CD8+ T cell epitopes presented by HLA-A*2601. Vaccine 2005 23 3783 90.
    • (2005) Vaccine , vol.23 , pp. 3783-90
    • Satoh, M.1    Takamiya, Y.2    Oka, S.3    Tokunaga, K.4    Takiguchi, M.5
  • 33
    • 19444377294 scopus 로고    scopus 로고
    • Identification of T cell epitopes by the use of rapidly generated mRNA fragments
    • Britten CM Meyer RG Graf C Huber C Wolfel T. Identification of T cell epitopes by the use of rapidly generated mRNA fragments. J. Immunol. Methods 2005 299 165 75.
    • (2005) J. Immunol. Methods , vol.299 , pp. 165-75
    • Britten, C.M.1    Meyer, R.G.2    Graf, C.3    Huber, C.4    Wolfel, T.5
  • 34
    • 24644454167 scopus 로고    scopus 로고
    • Chlamydia pneumoniae genome sequence analysis and identification of HLA-A2-restricted CD8+ T cell epitopes recognized by infection-primed T cells
    • Capo S Nuti S Scarselli M et al. Chlamydia pneumoniae genome sequence analysis and identification of HLA-A2-restricted CD8+ T cell epitopes recognized by infection-primed T cells. Vaccine 2005 23 5028 37.
    • (2005) Vaccine , vol.23 , pp. 5028-37
    • Capo, S.1    Nuti, S.2    Scarselli, M.3
  • 35
    • 16244377732 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis genome-wide screen exposes multiple CD8 T cell epitopes
    • Hammond AS Klein MR Corrah T et al. Mycobacterium tuberculosis genome-wide screen exposes multiple CD8 T cell epitopes. Clin. Exp. Immunol. 2005 140 109 16.
    • (2005) Clin. Exp. Immunol , vol.140 , pp. 109-16
    • Hammond, A.S.1    Klein, M.R.2    Corrah, T.3
  • 36
    • 21144435504 scopus 로고    scopus 로고
    • Identification of multiple HLA-A*0201-restricted cruzipain and FL-160 CD8+ epitopes recognized by T cells from chronically Trypanosoma cruzi-infected patients
    • Fonseca SG Moins-Teisserenc H Clave E et al. Identification of multiple HLA-A*0201-restricted cruzipain and FL-160 CD8+ epitopes recognized by T cells from chronically Trypanosoma cruzi-infected patients. Microbes Infect. 2005 7 688 97.
    • (2005) Microbes Infect , vol.7 , pp. 688-97
    • Fonseca, S.G.1    Moins-Teisserenc, H.2    Clave, E.3
  • 37
    • 21344433224 scopus 로고    scopus 로고
    • Identification of naturally processed HLA-A2 - Restricted proinsulin epitopes by reverse immunology
    • Hassainya Y Garcia-Pons F Kratzer R et al. Identification of naturally processed HLA-A2 - restricted proinsulin epitopes by reverse immunology. Diabetes 2005 54 2053 9.
    • (2005) Diabetes , vol.54 , pp. 2053-9
    • Hassainya, Y.1    Garcia-Pons, F.2    Kratzer, R.3
  • 38
    • 0033579910 scopus 로고    scopus 로고
    • A MAGE-1-encoded HLA-A24-binding synthetic peptide induces specific anti-tumor cytotoxic T lymphocytes
    • Fujie T Tahara K Tanaka F Mori M Takesako K Akiyoshi T. A MAGE-1-encoded HLA-A24-binding synthetic peptide induces specific anti-tumor cytotoxic T lymphocytes. Int. J. Cancer 1999 80 169 72.
    • (1999) Int. J. Cancer , vol.80 , pp. 169-72
    • Fujie, T.1    Tahara, K.2    Tanaka, F.3    Mori, M.4    Takesako, K.5    Akiyoshi, T.6
  • 39
    • 0031937298 scopus 로고    scopus 로고
    • The multi-epitope approach for immunotherapy for cancer: Identification of several CTL epitopes from various tumor-associated antigens expressed on solid epithelial tumors
    • Kawashima I Hudson SJ Tsai V et al. The multi-epitope approach for immunotherapy for cancer: identification of several CTL epitopes from various tumor-associated antigens expressed on solid epithelial tumors. Hum. Immunol. 1998 59 1 14.
    • (1998) Hum. Immunol , vol.59 , pp. 1-14
    • Kawashima, I.1    Hudson, S.J.2    Tsai, V.3
  • 40
    • 0028607185 scopus 로고
    • A peptide encoded by human gene MAGE-3 and presented by HLA-A2 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE-3
    • van der Bruggen P Bastin J Gajewski T et al. A peptide encoded by human gene MAGE-3 and presented by HLA-A2 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE-3. Eur. J. Immunol. 1994 24 3038 43.
    • (1994) Eur. J. Immunol , vol.24 , pp. 3038-43
    • Van Der Bruggen, P.1    Bastin, J.2    Gajewski, T.3
  • 41
    • 0029875680 scopus 로고    scopus 로고
    • A peptide encoded by the human MAGE3 gene and presented by HLA-B44 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE3
    • Herman J van der Bruggen P Luescher IF et al. A peptide encoded by the human MAGE3 gene and presented by HLA-B44 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE3. Immunogenetics 1996 43 377 83.
    • (1996) Immunogenetics , vol.43 , pp. 377-83
    • Herman, J.1    Van Der Bruggen, P.2    Luescher, I.F.3
  • 42
    • 0030871041 scopus 로고    scopus 로고
    • Induction of antitumor cytotoxic T lymphocytes with a MAGE-3-encoded synthetic peptide presented by human leukocytes antigen-A24
    • Tanaka F Fujie T Tahara K et al. Induction of antitumor cytotoxic T lymphocytes with a MAGE-3-encoded synthetic peptide presented by human leukocytes antigen-A24. Cancer Res. 1997 57 4465 8.
    • (1997) Cancer Res , vol.57 , pp. 4465-8
    • Tanaka, F.1    Fujie, T.2    Tahara, K.3
  • 43
    • 0032212445 scopus 로고    scopus 로고
    • Identification of a shared HLA-A*0201-restricted T-cell epitope from the melanoma antigen tyrosinase-related protein 2 (TRP2)
    • Parkhurst MR Fitzgerald EB Southwood S Sette A Rosenberg SA Kawakami Y. Identification of a shared HLA-A*0201-restricted T-cell epitope from the melanoma antigen tyrosinase-related protein 2 (TRP2). Cancer Res. 1998 58 4895 901.
    • (1998) Cancer Res , vol.58 , pp. 4895-901
    • Parkhurst, M.R.1    Fitzgerald, E.B.2    Southwood, S.3    Sette, A.4    Rosenberg, S.A.5    Kawakami, Y.6
  • 44
    • 0031568658 scopus 로고    scopus 로고
    • Identification of subdominant CTL epitopes of the GP100 melanoma-associated tumor antigen by primary in vitro immunization with peptide-pulsed dendritic cells
    • Tsai V Southwood S Sidney J et al. Identification of subdominant CTL epitopes of the GP100 melanoma-associated tumor antigen by primary in vitro immunization with peptide-pulsed dendritic cells. J. Immunol. 1997 158 1796 802.
    • (1997) J. Immunol , vol.158 , pp. 1796-802
    • Tsai, V.1    Southwood, S.2    Sidney, J.3
  • 45
    • 0037083354 scopus 로고    scopus 로고
    • Proteasome-assisted identification of a SSX-2-derived epitope recognized by tumor-reactive CTL infiltrating metastatic melanoma
    • Ayyoub M Stevanovic S Sahin U et al. Proteasome-assisted identification of a SSX-2-derived epitope recognized by tumor-reactive CTL infiltrating metastatic melanoma. J. Immunol. 2002 168 1717 22.
    • (2002) J. Immunol , vol.168 , pp. 1717-22
    • Ayyoub, M.1    Stevanovic, S.2    Sahin, U.3
  • 46
    • 0035182192 scopus 로고    scopus 로고
    • Efficient identification of novel HLA-A(*)0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated digestion analysis
    • Kessler JH Beekman NJ Bres-Vloemans SA et al. Efficient identification of novel HLA-A(*)0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated digestion analysis. J. Exp. Med. 2001 193 73 88.
    • (2001) J. Exp. Med , vol.193 , pp. 73-88
    • Kessler, J.H.1    Beekman, N.J.2    Bres-Vloemans, S.A.3
  • 47
    • 0347625928 scopus 로고    scopus 로고
    • EphA2 as target of anticancer immunotherapy: Identification of HLA-A*0201-restricted epitopes
    • Alves PM Faure O Graff-Dubois S et al. EphA2 as target of anticancer immunotherapy: identification of HLA-A*0201-restricted epitopes. Cancer Res. 2003 63 8476 80.
    • (2003) Cancer Res , vol.63 , pp. 8476-80
    • Alves, P.M.1    Faure, O.2    Graff-Dubois, S.3
  • 49
    • 0037342270 scopus 로고    scopus 로고
    • Quantitating protein synthesis, degradation, and endogenous antigen processing
    • Princiotta MF Finzi D Qian SB et al. Quantitating protein synthesis, degradation, and endogenous antigen processing. Immunity 2003 18 343 54.
    • (2003) Immunity , vol.18 , pp. 343-54
    • Princiotta, M.F.1    Finzi, D.2    Qian, S.B.3
  • 51
    • 9144273779 scopus 로고    scopus 로고
    • Inducible Hsp70 as target of anticancer immunotherapy: Identification of HLA-A*0201-restricted epitopes
    • Faure O Graff-Dubois S Bretaudeau L et al. Inducible Hsp70 as target of anticancer immunotherapy: identification of HLA-A*0201-restricted epitopes. Int. J. Cancer 2004 108 863 70.
    • (2004) Int. J. Cancer , vol.108 , pp. 863-70
    • Faure, O.1    Graff-Dubois, S.2    Bretaudeau, L.3
  • 52
    • 12644276375 scopus 로고    scopus 로고
    • A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening
    • Chen YT Scanlan MJ Sahin U et al. A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening. Proc. Natl Acad. Sci. USA 1997 94 1914 18.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 1914-18
    • Chen, Y.T.1    Scanlan, M.J.2    Sahin, U.3
  • 53
    • 0344351839 scopus 로고    scopus 로고
    • Serological analysis of human tumor antigens: Molecular definition and implications
    • Tureci O Sahin U Pfreundschuh M. Serological analysis of human tumor antigens: molecular definition and implications. Mol. Med. Today 1997 3 342 9.
    • (1997) Mol. Med. Today , vol.3 , pp. 342-9
    • Tureci, O.1    Sahin, U.2    Pfreundschuh, M.3
  • 54
    • 3042803522 scopus 로고    scopus 로고
    • Identification of tumor antigens as potential target antigens for immunotherapy by serological expression cloning
    • Jager D Taverna C Zippelius A Knuth A. Identification of tumor antigens as potential target antigens for immunotherapy by serological expression cloning. Cancer Immunol. Immunother. 2004 53 144 7.
    • (2004) Cancer Immunol. Immunother , vol.53 , pp. 144-7
    • Jager, D.1    Taverna, C.2    Zippelius, A.3    Knuth, A.4
  • 55
    • 24344435109 scopus 로고    scopus 로고
    • Serological identification of breast cancer-related antigens from a Saccharomyces cerevisiae surface display library
    • Wadle A Mischo A Imig J et al. Serological identification of breast cancer-related antigens from a Saccharomyces cerevisiae surface display library. Int. J. Cancer 2005 117 104 13.
    • (2005) Int. J. Cancer , vol.117 , pp. 104-13
    • Wadle, A.1    Mischo, A.2    Imig, J.3
  • 57
    • 28644442984 scopus 로고    scopus 로고
    • Proteomics-based identification of human acute leukemia antigens that induce humoral immune response
    • Cui JW Li WH Wang J et al. Proteomics-based identification of human acute leukemia antigens that induce humoral immune response. Mol. Cell Proteomics 2005 4 1718 24.
    • (2005) Mol. Cell Proteomics , vol.4 , pp. 1718-24
    • Cui, J.W.1    Li, W.H.2    Wang, J.3
  • 59
    • 12444310169 scopus 로고    scopus 로고
    • Haptoglobin-alpha subunit as potential serum biomarker in ovarian cancer: Identification and characterization using proteomic profiling and mass spectrometry
    • Ye B Cramer DW Skates SJ et al. Haptoglobin-alpha subunit as potential serum biomarker in ovarian cancer: identification and characterization using proteomic profiling and mass spectrometry. Clin. Cancer Res. 2003 9 2904 11.
    • (2003) Clin. Cancer Res , vol.9 , pp. 2904-11
    • Ye, B.1    Cramer, D.W.2    Skates, S.J.3
  • 60
    • 9144251970 scopus 로고    scopus 로고
    • Gene expression profiling identifies clinically relevant subtypes of prostate cancer
    • Lapointe J Li C Higgins JP et al. Gene expression profiling identifies clinically relevant subtypes of prostate cancer. Proc. Natl Acad. Sci. USA 2004 101 811 16.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 811-16
    • Lapointe, J.1    Li, C.2    Higgins, J.P.3
  • 61
    • 0344127560 scopus 로고    scopus 로고
    • Gene expression patterns in renal cell carcinoma assessed by complementary DNA microarray
    • Higgins JP Shinghal R Gill H et al. Gene expression patterns in renal cell carcinoma assessed by complementary DNA microarray. Am. J. Pathol. 2003 162 925 32.
    • (2003) Am. J. Pathol , vol.162 , pp. 925-32
    • Higgins, J.P.1    Shinghal, R.2    Gill, H.3
  • 62
    • 0037099668 scopus 로고    scopus 로고
    • Combined use of oligonucleotide and tissue microarrays identifies cancer/testis antigens as biomarkers in lung carcinoma
    • Sugita M Geraci M Gao B et al. Combined use of oligonucleotide and tissue microarrays identifies cancer/testis antigens as biomarkers in lung carcinoma. Cancer Res. 2002 62 3971 9.
    • (2002) Cancer Res , vol.62 , pp. 3971-9
    • Sugita, M.1    Geraci, M.2    Gao, B.3
  • 63
    • 24944479468 scopus 로고    scopus 로고
    • 'The 39 steps' in gene expression profiling: Critical issues and proposed best practices for microarray experiments
    • Imbeaud S Auffray C. 'The 39 steps' in gene expression profiling: critical issues and proposed best practices for microarray experiments. Drug Discov. Today 2005 10 1175 82.
    • (2005) Drug Discov. Today , vol.10 , pp. 1175-82
    • Imbeaud, S.1    Auffray, C.2
  • 65
    • 0034130561 scopus 로고    scopus 로고
    • Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays
    • Brenner S Johnson M Bridgham J et al. Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays. Nat. Biotechnol. 2000 18 630 34.
    • (2000) Nat. Biotechnol , vol.18 , pp. 630-34
    • Brenner, S.1    Johnson, M.2    Bridgham, J.3
  • 66
    • 0034660855 scopus 로고    scopus 로고
    • Identification on a human sarcoma of two new genes with tumor-specific expression
    • Martelange V De Smet C De Plaen E Lurquin C Boon T. Identification on a human sarcoma of two new genes with tumor-specific expression. Cancer Res. 2000 60 3848 55.
    • (2000) Cancer Res , vol.60 , pp. 3848-55
    • Martelange, V.1    De Smet, C.2    De Plaen, E.3    Lurquin, C.4    Boon, T.5
  • 67
    • 9144250267 scopus 로고    scopus 로고
    • Identification of human tumor antigens and its implications for diagnosis and treatment of cancer
    • Kawakami Y Fujita T Matsuzaki Y et al. Identification of human tumor antigens and its implications for diagnosis and treatment of cancer. Cancer Sci. 2004 95 784 91.
    • (2004) Cancer Sci , vol.95 , pp. 784-91
    • Kawakami, Y.1    Fujita, T.2    Matsuzaki, Y.3
  • 69
    • 0037207069 scopus 로고    scopus 로고
    • Gene expression profiling: Methodological challenges, results, and prospects for addiction research
    • Pollock JD. Gene expression profiling: methodological challenges, results, and prospects for addiction research. Chem. Phys. Lipids 2002 121 241 56.
    • (2002) Chem. Phys. Lipids , vol.121 , pp. 241-56
    • Pollock, J.D.1
  • 70
    • 13444260761 scopus 로고    scopus 로고
    • Statistical analysis of MPSS measurements: Application to the study of LPS-activated macrophage gene expression
    • Stolovitzky GA Kundaje A Held GA et al. Statistical analysis of MPSS measurements: application to the study of LPS-activated macrophage gene expression. Proc. Natl Acad. Sci. USA 2005 102 1402 7.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 1402-7
    • Stolovitzky, G.A.1    Kundaje, A.2    Held, G.A.3
  • 71
    • 9644301089 scopus 로고    scopus 로고
    • The MMA1 gene family of cancer-testis antigens has multiple alternative splice variants: Characterization of their expression profile, the genomic organization, and transcript properties
    • de Wit NJ Cornelissen IM Diepstra JH Weidle UH Ruiter DJ van Muijen GN. The MMA1 gene family of cancer-testis antigens has multiple alternative splice variants: characterization of their expression profile, the genomic organization, and transcript properties. Genes Chromosomes Cancer 2005 42 10 21.
    • (2005) Genes Chromosomes Cancer , vol.42 , pp. 10-21
    • De Wit, N.J.1    Cornelissen, I.M.2    Diepstra, J.H.3    Weidle, U.H.4    Ruiter, D.J.5    Van Muijen, G.N.6
  • 72
    • 0036533634 scopus 로고    scopus 로고
    • Expression profiling of MMA-1a and splice variant MMA-1b: New cancer/testis antigens identified in human melanoma
    • de Wit NJ Weidle UH Ruiter DJ van Muijen GN. Expression profiling of MMA-1a and splice variant MMA-1b: new cancer/testis antigens identified in human melanoma. Int. J. Cancer 2002 98 547 53.
    • (2002) Int. J. Cancer , vol.98 , pp. 547-53
    • De Wit, N.J.1    Weidle, U.H.2    Ruiter, D.J.3    Van Muijen, G.N.4
  • 73
    • 10744226338 scopus 로고    scopus 로고
    • Identification and characterization of KAT, a novel gene preferentially expressed in several human cancer cell lines
    • Wenzel K Felix SB Flachmeier C et al. Identification and characterization of KAT, a novel gene preferentially expressed in several human cancer cell lines. Biol. Chem. 2003 384 763 75.
    • (2003) Biol. Chem , vol.384 , pp. 763-75
    • Wenzel, K.1    Felix, S.B.2    Flachmeier, C.3
  • 74
    • 24144491588 scopus 로고    scopus 로고
    • Identification of new splice variants and differential expression of the human kallikrein 10 gene, a candidate cancer biomarker
    • Yousef GM White NM Michael IP et al. Identification of new splice variants and differential expression of the human kallikrein 10 gene, a candidate cancer biomarker. Tumour Biol. 2005 26 227 35.
    • (2005) Tumour Biol , vol.26 , pp. 227-35
    • Yousef, G.M.1    White, N.M.2    Michael, I.P.3
  • 75
    • 2442551589 scopus 로고    scopus 로고
    • Identification of alternatively spliced mRNA variants related to cancers by genome-wide ESTs alignment
    • Hui L Zhang X Wu X et al. Identification of alternatively spliced mRNA variants related to cancers by genome-wide ESTs alignment. Oncogene 2004 23 3013 23.
    • (2004) Oncogene , vol.23 , pp. 3013-23
    • Hui, L.1    Zhang, X.2    Wu, X.3
  • 76
    • 0037310045 scopus 로고    scopus 로고
    • Computational analysis and experimental validation of tumor-associated alternative RNA splicing in human cancer
    • Wang Z Lo HS Yang H et al. Computational analysis and experimental validation of tumor-associated alternative RNA splicing in human cancer. Cancer Res. 2003 63 655 7.
    • (2003) Cancer Res , vol.63 , pp. 655-7
    • Wang, Z.1    Lo, H.S.2    Yang, H.3
  • 78
    • 7944223046 scopus 로고    scopus 로고
    • Computational methods for prediction of T-cell epitopes - A framework for modelling, testing, and applications
    • Brusic V Bajic VB Petrovsky N. Computational methods for prediction of T-cell epitopes - a framework for modelling, testing, and applications. Methods 2004 34 436 43.
    • (2004) Methods , vol.34 , pp. 436-43
    • Brusic, V.1    Bajic, V.B.2    Petrovsky, N.3
  • 79
    • 0033866228 scopus 로고    scopus 로고
    • An automated prediction of MHC class I-binding peptides based on positional scanning with peptide libraries
    • Udaka K Wiesmuller KH Kienle S et al. An automated prediction of MHC class I-binding peptides based on positional scanning with peptide libraries. Immunogenetics 2000 51 816 28.
    • (2000) Immunogenetics , vol.51 , pp. 816-28
    • Udaka, K.1    Wiesmuller, K.H.2    Kienle, S.3
  • 80
    • 3242683893 scopus 로고    scopus 로고
    • BioInformatics and Molecular Analysis Section, Center for Information Technology Cited March 2005. Available from URL
    • BioInformatics and Molecular Analysis Section, Center for Information Technology. HLA Peptide Binding Predictions. Cited March 2005. Available from URL http://bimas.dcrt.nih.gov/molbio/hla_bind/.
    • HLA Peptide Binding Predictions
  • 81
    • 0028052724 scopus 로고
    • Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains
    • Parker KC Bednarek MA Coligan JE. Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains. J. Immunol. 1994 152 163 75.
    • (1994) J. Immunol , vol.152 , pp. 163-75
    • Parker, K.C.1    Bednarek, M.A.2    Coligan, J.E.3
  • 82
    • 33646094663 scopus 로고    scopus 로고
    • Department of Immunology, Institute for Cell Biology BMI-Heidelberg. Cited July 2005. Available from URL
    • Department of Immunology, Institute for Cell Biology BMI-Heidelberg. Cited July 2005. Available from URL http://www.syfpeithi.de/.
  • 84
    • 20544463394 scopus 로고    scopus 로고
    • Antigen processing is predictable: From genes to T cell epitopes
    • Stevanovic S. Antigen processing is predictable: from genes to T cell epitopes. Transpl. Immunol. 2005 14 171 4.
    • (2005) Transpl. Immunol , vol.14 , pp. 171-4
    • Stevanovic, S.1
  • 85
    • 25844525530 scopus 로고    scopus 로고
    • Classification of A1- and A24-supertype molecules by analysis of their MHC-peptide binding repertoires
    • Sidney J Southwood S Sette A. Classification of A1- and A24-supertype molecules by analysis of their MHC-peptide binding repertoires. Immunogenetics 2005 57 393 408.
    • (2005) Immunogenetics , vol.57 , pp. 393-408
    • Sidney, J.1    Southwood, S.2    Sette, A.3
  • 86
    • 0030825370 scopus 로고    scopus 로고
    • A novel, highly efficient peptide-HLA class I binding assay using unfolded heavy chain molecules: Identification of HIV-1 derived peptides that bind to HLA-A*0201 and HLA-A*0301
    • Tan TL Geluk A Toebes M Ottenhoff TH Drijfhout JW. A novel, highly efficient peptide-HLA class I binding assay using unfolded heavy chain molecules: identification of HIV-1 derived peptides that bind to HLA-A*0201 and HLA-A*0301. J. Immunol. Methods 1997 205 201 9.
    • (1997) J. Immunol. Methods , vol.205 , pp. 201-9
    • Tan, T.L.1    Geluk, A.2    Toebes, M.3    Ottenhoff, T.H.4    Drijfhout, J.W.5
  • 87
    • 0028295047 scopus 로고
    • Role of HLA-A motifs in identification of potential CTL epitopes in human papillomavirus type 16 E6 and E7 proteins
    • Kast WM Brandt RM Sidney J et al. Role of HLA-A motifs in identification of potential CTL epitopes in human papillomavirus type 16 E6 and E7 proteins. J. Immunol. 1994 152 3904 12.
    • (1994) J. Immunol , vol.152 , pp. 3904-12
    • Kast, W.M.1    Brandt, R.M.2    Sidney, J.3
  • 88
    • 0025076114 scopus 로고
    • Empty MHC class I molecules come out in the cold
    • Ljunggren HG Stam NJ Ohlen C et al. Empty MHC class I molecules come out in the cold. Nature 1990 346 476 80.
    • (1990) Nature , vol.346 , pp. 476-80
    • Ljunggren, H.G.1    Stam, N.J.2    Ohlen, C.3
  • 89
    • 0026593016 scopus 로고
    • Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex
    • Kelly A Powis SH Kerr LA et al. Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex. Nature 1992 355 641 4.
    • (1992) Nature , vol.355 , pp. 641-4
    • Kelly, A.1    Powis, S.H.2    Kerr, L.A.3
  • 90
    • 0029152771 scopus 로고
    • Amino-terminal alteration of the HLA-A*0201-restricted human immunodeficiency virus pol peptide increases complex stability and in vitro immunogenicity
    • Pogue RR Eron J Frelinger JA Matsui M. Amino-terminal alteration of the HLA-A*0201-restricted human immunodeficiency virus pol peptide increases complex stability and in vitro immunogenicity. Proc. Natl Acad. Sci. USA 1995 92 8166 70.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 8166-70
    • Pogue, R.R.1    Eron, J.2    Frelinger, J.A.3    Matsui, M.4
  • 91
    • 0037314043 scopus 로고    scopus 로고
    • Competition-based cellular peptide binding assays for 13 prevalent HLA class I alleles using fluorescein-labeled synthetic peptides
    • Kessler JH Mommaas B Mutis T et al. Competition-based cellular peptide binding assays for 13 prevalent HLA class I alleles using fluorescein-labeled synthetic peptides. Hum. Immunol. 2003 64 245 55.
    • (2003) Hum. Immunol , vol.64 , pp. 245-55
    • Kessler, J.H.1    Mommaas, B.2    Mutis, T.3
  • 92
    • 0023945080 scopus 로고
    • Synthetic peptides as antigens and competitors in recognition by H-2-restricted cytolytic T cells specific for HLA
    • Maryanski JL Pala P Cerottini JC Corradin G. Synthetic peptides as antigens and competitors in recognition by H-2-restricted cytolytic T cells specific for HLA. J. Exp. Med. 1988 167 1391 405.
    • (1988) J. Exp. Med , vol.167 , pp. 1391-405
    • Maryanski, J.L.1    Pala, P.2    Cerottini, J.C.3    Corradin, G.4
  • 94
    • 0027399839 scopus 로고
    • A method to quantify binding of unlabeled peptides to class I MHC molecules and detect their allele specificity
    • Elvin J Potter C Elliott T Cerundolo V Townsend A. A method to quantify binding of unlabeled peptides to class I MHC molecules and detect their allele specificity. J. Immunol. Methods 1993 158 161 71.
    • (1993) J. Immunol. Methods , vol.158 , pp. 161-71
    • Elvin, J.1    Potter, C.2    Elliott, T.3    Cerundolo, V.4    Townsend, A.5
  • 95
    • 0027074320 scopus 로고
    • Thermal stability comparison of purified empty and peptide-filled forms of a class I MHC molecule
    • Fahnestock ML Tamir I Narhi L Bjorkman PJ. Thermal stability comparison of purified empty and peptide-filled forms of a class I MHC molecule. Science 1992 258 1658 62.
    • (1992) Science , vol.258 , pp. 1658-62
    • Fahnestock, M.L.1    Tamir, I.2    Narhi, L.3    Bjorkman, P.J.4
  • 97
    • 0027955071 scopus 로고
    • A quantitative assay to measure the interaction between immunogenic peptides and purified class I major histocompatibility complex molecules
    • Olsen AC Pedersen LO Hansen AS et al. A quantitative assay to measure the interaction between immunogenic peptides and purified class I major histocompatibility complex molecules. Eur. J. Immunol. 1994 24 385 92.
    • (1994) Eur. J. Immunol , vol.24 , pp. 385-92
    • Olsen, A.C.1    Pedersen, L.O.2    Hansen, A.S.3
  • 98
    • 0035452568 scopus 로고    scopus 로고
    • Use of fluorescence polarization to monitor MHC-peptide interactions in solution
    • Dedier S Reinelt S Rion S Folkers G Rognan D. Use of fluorescence polarization to monitor MHC-peptide interactions in solution. J. Immunol. Methods 2001 255 57 66.
    • (2001) J. Immunol. Methods , vol.255 , pp. 57-66
    • Dedier, S.1    Reinelt, S.2    Rion, S.3    Folkers, G.4    Rognan, D.5
  • 99
    • 24944541417 scopus 로고    scopus 로고
    • Development and validation of a fluorescence polarization-based competitive peptide-binding assay for HLA-A*0201 - A new tool for epitope discovery
    • Buchli R VanGundy RS Hickman-Miller HD Giberson CF Bardet W Hildebrand WH. Development and validation of a fluorescence polarization-based competitive peptide-binding assay for HLA-A*0201 - a new tool for epitope discovery. Biochemistry 2005 44 12 491 507.
    • (2005) Biochemistry , vol.44 , pp. 12491-507
    • Buchli, R.1    Vangundy, R.S.2    Hickman-Miller, H.D.3    Giberson, C.F.4    Bardet, W.5    Hildebrand, W.H.6
  • 100
    • 22744444096 scopus 로고    scopus 로고
    • HLA class I transgenic mice: Development, utilisation and improvement
    • Pascolo S. HLA class I transgenic mice: development, utilisation and improvement. Expert Opin. Biol. Ther. 2005 5 919 38.
    • (2005) Expert Opin. Biol. Ther , vol.5 , pp. 919-38
    • Pascolo, S.1
  • 102
    • 17044415359 scopus 로고    scopus 로고
    • Increased immunogenicity of an anchor-modified tumor-associated antigen is due to the enhanced stability of the peptide/MHC complex: Implications for vaccine design
    • Borbulevych OY Baxter TK Yu Z Restifo NP Baker BM. Increased immunogenicity of an anchor-modified tumor-associated antigen is due to the enhanced stability of the peptide/MHC complex: implications for vaccine design. J. Immunol. 2005 174 4812 20.
    • (2005) J. Immunol , vol.174 , pp. 4812-20
    • Borbulevych, O.Y.1    Baxter, T.K.2    Yu, Z.3    Restifo, N.P.4    Baker, B.M.5
  • 103
    • 4444264828 scopus 로고    scopus 로고
    • Antigenicity and immunogenicity of peptide analogues of a low affinity peptide of the human telomerase reverse transcriptase tumor antigen
    • Hernandez J Schoeder K Blondelle SE et al. Antigenicity and immunogenicity of peptide analogues of a low affinity peptide of the human telomerase reverse transcriptase tumor antigen. Eur. J. Immunol. 2004 34 2331 41.
    • (2004) Eur. J. Immunol , vol.34 , pp. 2331-41
    • Hernandez, J.1    Schoeder, K.2    Blondelle, S.E.3
  • 104
    • 0035995962 scopus 로고    scopus 로고
    • Amino acid modifications in the wild type sequence p53 232-240 overcome the poor immunogenicity of this self tumour epitope
    • Baratin M Kayibanda M Ziol M et al. Amino acid modifications in the wild type sequence p53 232-240 overcome the poor immunogenicity of this self tumour epitope. J. Pept. Sci. 2002 8 327 34.
    • (2002) J. Pept. Sci , vol.8 , pp. 327-34
    • Baratin, M.1    Kayibanda, M.2    Ziol, M.3
  • 105
    • 0036201441 scopus 로고    scopus 로고
    • Relationship between kinetic stability and immunogenicity of HLA-DR4/peptide complexes
    • Hall FC Rabinowitz JD Busch R et al. Relationship between kinetic stability and immunogenicity of HLA-DR4/peptide complexes. Eur. J. Immunol. 2002 32 662 70.
    • (2002) Eur. J. Immunol , vol.32 , pp. 662-70
    • Hall, F.C.1    Rabinowitz, J.D.2    Busch, R.3
  • 106
    • 0029974607 scopus 로고    scopus 로고
    • Immunogenicity of peptides bound to MHC class I molecules depends on the MHC-peptide complex stability
    • van der Burg SH Visseren MJ Brandt RM Kast WM Melief CJ. Immunogenicity of peptides bound to MHC class I molecules depends on the MHC-peptide complex stability. J. Immunol. 1996 156 3308 14.
    • (1996) J. Immunol , vol.156 , pp. 3308-14
    • Van Der Burg, S.H.1    Visseren, M.J.2    Brandt, R.M.3    Kast, W.M.4    Melief, C.J.5
  • 108
    • 0036644634 scopus 로고    scopus 로고
    • Generation of CTL recognizing an HLA-A*0201-restricted epitope shared by MAGE-A1, -A2, -A3, -A4, -A6, -A10, and -A12 tumor antigens: Implication in a broad-spectrum tumor immunotherapy
    • Graff-Dubois S Faure O Gross DA et al. Generation of CTL recognizing an HLA-A*0201-restricted epitope shared by MAGE-A1, -A2, -A3, -A4, -A6, -A10, and -A12 tumor antigens: implication in a broad-spectrum tumor immunotherapy. J. Immunol. 2002 169 575 80.
    • (2002) J. Immunol , vol.169 , pp. 575-80
    • Graff-Dubois, S.1    Faure, O.2    Gross, D.A.3
  • 109
    • 22244458905 scopus 로고    scopus 로고
    • Human CTL epitopes prostatic acid phosphatase-3 and six-transmembrane epithelial antigen of prostate-3 as candidates for prostate cancer immunotherapy
    • Machlenkin A Paz A Bar Haim E et al. Human CTL epitopes prostatic acid phosphatase-3 and six-transmembrane epithelial antigen of prostate-3 as candidates for prostate cancer immunotherapy. Cancer Res. 2005 65 6435 42.
    • (2005) Cancer Res , vol.65 , pp. 6435-42
    • Machlenkin, A.1    Paz, A.2    Bar Haim, E.3
  • 110
    • 27644476543 scopus 로고    scopus 로고
    • Optimum in vitro expansion of human antigen-specific CD8 T cells for adoptive transfer therapy
    • Montes M Rufer N Appay V et al. Optimum in vitro expansion of human antigen-specific CD8 T cells for adoptive transfer therapy. Clin. Exp. Immunol. 2005 142 292 302.
    • (2005) Clin. Exp. Immunol , vol.142 , pp. 292-302
    • Montes, M.1    Rufer, N.2    Appay, V.3
  • 111
    • 0035421798 scopus 로고    scopus 로고
    • Mature dendritic cells prime functionally superior melan-A-specific CD8+ lymphocytes as compared with nonprofessional APC
    • Salio M Shepherd D Dunbar PR et al. Mature dendritic cells prime functionally superior melan-A-specific CD8+ lymphocytes as compared with nonprofessional APC. J. Immunol. 2001 167 1188 97.
    • (2001) J. Immunol , vol.167 , pp. 1188-97
    • Salio, M.1    Shepherd, D.2    Dunbar, P.R.3
  • 112
    • 20444498276 scopus 로고    scopus 로고
    • Artificial antigen-presenting cells transduced with telomerase efficiently expand epitope-specific, human leukocyte antigen-restricted cytotoxic T cells
    • Dupont J Latouche JB Ma C Sadelain M. Artificial antigen-presenting cells transduced with telomerase efficiently expand epitope-specific, human leukocyte antigen-restricted cytotoxic T cells. Cancer Res. 2005 65 5417 27.
    • (2005) Cancer Res , vol.65 , pp. 5417-27
    • Dupont, J.1    Latouche, J.B.2    Ma, C.3    Sadelain, M.4
  • 113
    • 0038587735 scopus 로고    scopus 로고
    • Ex vivo induction and expansion of antigen-specific cytotoxic T cells by HLA-Ig-coated artificial antigen-presenting cells
    • Oelke M Maus MV Didiano D June CH Mackensen A Schneck JP. Ex vivo induction and expansion of antigen-specific cytotoxic T cells by HLA-Ig-coated artificial antigen-presenting cells. Nat. Med. 2003 9 619 24.
    • (2003) Nat. Med , vol.9 , pp. 619-24
    • Oelke, M.1    Maus, M.V.2    Didiano, D.3    June, C.H.4    MacKensen, A.5    Schneck, J.P.6
  • 114
    • 20444482839 scopus 로고    scopus 로고
    • Recognition of six-transmembrane epithelial antigen of the prostate-expressing tumor cells by peptide antigen-induced cytotoxic T lymphocytes
    • Rodeberg DA Nuss RA Elsawa SF Celis E. Recognition of six-transmembrane epithelial antigen of the prostate-expressing tumor cells by peptide antigen-induced cytotoxic T lymphocytes. Clin. Cancer Res. 2005 11 4545 52.
    • (2005) Clin. Cancer Res , vol.11 , pp. 4545-52
    • Rodeberg, D.A.1    Nuss, R.A.2    Elsawa, S.F.3    Celis, E.4
  • 115
    • 0031469361 scopus 로고    scopus 로고
    • CD40-activated human B cells: An alternative source of highly efficient antigen presenting cells to generate autologous antigen-specific T cells for adoptive immunotherapy
    • Schultze JL Michalak S Seamon MJ et al. CD40-activated human B cells: an alternative source of highly efficient antigen presenting cells to generate autologous antigen-specific T cells for adoptive immunotherapy. J. Clin. Invest. 1997 100 2757 65.
    • (1997) J. Clin. Invest , vol.100 , pp. 2757-65
    • Schultze, J.L.1    Michalak, S.2    Seamon, M.J.3
  • 116
    • 0028675323 scopus 로고
    • Development of high potency universal DR-restricted helper epitopes by modification of high affinity DR-blocking peptides
    • Alexander J Sidney J Southwood S et al. Development of high potency universal DR-restricted helper epitopes by modification of high affinity DR-blocking peptides. Immunity 1994 1 751 61.
    • (1994) Immunity , vol.1 , pp. 751-61
    • Alexander, J.1    Sidney, J.2    Southwood, S.3
  • 117
    • 0033514992 scopus 로고    scopus 로고
    • Native display of complete foreign protein domains on the surface of hepatitis B virus capsids
    • Kratz PA Bottcher B Nassal M. Native display of complete foreign protein domains on the surface of hepatitis B virus capsids. Proc. Natl Acad. Sci. USA 1999 96 1915 20.
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 1915-20
    • Kratz, P.A.1    Bottcher, B.2    Nassal, M.3
  • 119
    • 0035903324 scopus 로고    scopus 로고
    • Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
    • Sutmuller RP van Duivenvoorde LM van Elsas A et al. Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J. Exp. Med. 2001 194 823 32.
    • (2001) J. Exp. Med , vol.194 , pp. 823-32
    • Sutmuller, R.P.1    Van Duivenvoorde, L.M.2    Van Elsas, A.3
  • 120
    • 0019996202 scopus 로고
    • Limit-dilution assay and clonal expansion of all T cells capable of proliferation
    • Chen WF Wilson A Scollay R Shortman K. Limit-dilution assay and clonal expansion of all T cells capable of proliferation. J. Immunol. Methods 1982 52 307 22.
    • (1982) J. Immunol. Methods , vol.52 , pp. 307-22
    • Chen, W.F.1    Wilson, A.2    Scollay, R.3    Shortman, K.4
  • 121
    • 0034537736 scopus 로고    scopus 로고
    • Functional characterization of CD8(+) antigen-specific cytotoxic T lymphocytes after enrichment based on cytokine secretion: Comparison with the MHC-tetramer technology
    • Oelke M Kurokawa T Hentrich I et al. Functional characterization of CD8(+) antigen-specific cytotoxic T lymphocytes after enrichment based on cytokine secretion: comparison with the MHC-tetramer technology. Scand. J. Immunol. 2000 52 544 9.
    • (2000) Scand. J. Immunol , vol.52 , pp. 544-9
    • Oelke, M.1    Kurokawa, T.2    Hentrich, I.3
  • 122
    • 0033135052 scopus 로고    scopus 로고
    • An antigen-targeted approach to adoptive transfer therapy of cancer
    • Valmori D Pittet MJ Rimoldi D et al. An antigen-targeted approach to adoptive transfer therapy of cancer. Cancer Res. 1999 59 2167 73.
    • (1999) Cancer Res , vol.59 , pp. 2167-73
    • Valmori, D.1    Pittet, M.J.2    Rimoldi, D.3
  • 123
    • 14844363448 scopus 로고    scopus 로고
    • Mechanisms that limit the in vitro proliferative potential of human CD8+ T lymphocytes
    • Migliaccio M Raj K Menzel O Rufer N. Mechanisms that limit the in vitro proliferative potential of human CD8+ T lymphocytes. J. Immunol. 2005 174 3335 43.
    • (2005) J. Immunol , vol.174 , pp. 3335-43
    • Migliaccio, M.1    Raj, K.2    Menzel, O.3    Rufer, N.4
  • 124
    • 0035437179 scopus 로고    scopus 로고
    • Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential
    • Rufer N Migliaccio M Antonchuk J Humphries RK Roosnek E Lansdorp PM. Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential. Blood 2001 98 597 603.
    • (2001) Blood , vol.98 , pp. 597-603
    • Rufer, N.1    Migliaccio, M.2    Antonchuk, J.3    Humphries, R.K.4    Roosnek, E.5    Lansdorp, P.M.6
  • 125
    • 33646098624 scopus 로고    scopus 로고
    • Capture of antigen-specific T lymphocytes from human blood by selective immortalization to establish long-term T-cell lines maintaining primary cell characteristics
    • Barsov EV Andersen H Coalter VJ Carrington M Lifson JD Ott DE. Capture of antigen-specific T lymphocytes from human blood by selective immortalization to establish long-term T-cell lines maintaining primary cell characteristics. Immunol. Lett. 2005.
    • (2005) Immunol. Lett
    • Barsov, E.V.1    Andersen, H.2    Coalter, V.J.3    Carrington, M.4    Lifson, J.D.5    Ott, D.E.6
  • 126
    • 12144287161 scopus 로고    scopus 로고
    • Human telomerase reverse transcriptase-transduced human cytotoxic T cells suppress the growth of human melanoma in immunodeficient mice
    • Verra NC Jorritsma A Weijer K et al. Human telomerase reverse transcriptase-transduced human cytotoxic T cells suppress the growth of human melanoma in immunodeficient mice. Cancer Res. 2004 64 2153 61.
    • (2004) Cancer Res , vol.64 , pp. 2153-61
    • Verra, N.C.1    Jorritsma, A.2    Weijer, K.3
  • 128
    • 0036568413 scopus 로고    scopus 로고
    • TCR reconstitution in Jurkat reporter cells facilitates the identification of novel tumor antigens by cDNA expression cloning
    • Aarnoudse CA Kruse M Konopitzky R Brouwenstijn N Schrier PI. TCR reconstitution in Jurkat reporter cells facilitates the identification of novel tumor antigens by cDNA expression cloning. Int. J. Cancer 2002 99 7 13.
    • (2002) Int. J. Cancer , vol.99 , pp. 7-13
    • Aarnoudse, C.A.1    Kruse, M.2    Konopitzky, R.3    Brouwenstijn, N.4    Schrier, P.I.5
  • 129
    • 0033854866 scopus 로고    scopus 로고
    • Retargeting of a T cell line by anti MAGE-3/HLA-A2 alpha beta TCR gene transfer
    • Calogero A Hospers GA Kruse KM et al. Retargeting of a T cell line by anti MAGE-3/HLA-A2 alpha beta TCR gene transfer. Anticancer Res. 2000 20 1793 9.
    • (2000) Anticancer Res , vol.20 , pp. 1793-9
    • Calogero, A.1    Hospers, G.A.2    Kruse, K.M.3
  • 130
    • 16644382303 scopus 로고    scopus 로고
    • Methods for the ex vivo characterization of human CD8+ T subsets based on gene expression and replicative history analysis
    • Rufer N Reichenbach P Romero P. Methods for the ex vivo characterization of human CD8+ T subsets based on gene expression and replicative history analysis. Methods Mol. Med. 2005 109 265 84.
    • (2005) Methods Mol. Med , vol.109 , pp. 265-84
    • Rufer, N.1    Reichenbach, P.2    Romero, P.3
  • 131
    • 0030777911 scopus 로고    scopus 로고
    • MAGE-1 expression threshold for the lysis of melanoma cell lines by a specific cytotoxic T lymphocyte
    • Lethe B van der Bruggen P Brasseur F Boon T. MAGE-1 expression threshold for the lysis of melanoma cell lines by a specific cytotoxic T lymphocyte. Melanoma Res. 1997 7 Suppl. 2 S83 8.
    • (1997) Melanoma Res , vol.7 , Issue.SUPPL. 2 , pp. 83-8
    • Lethe, B.1    Van Der Bruggen, P.2    Brasseur, F.3    Boon, T.4
  • 132
    • 0035423121 scopus 로고    scopus 로고
    • Heterogeneous T-cell response to MAGE-A10(254-262): High avidity-specific cytolytic T lymphocytes show superior antitumor activity
    • Dutoit V Rubio-Godoy V Dietrich PY et al. Heterogeneous T-cell response to MAGE-A10(254-262): high avidity-specific cytolytic T lymphocytes show superior antitumor activity. Cancer Res. 2001 61 5850 56.
    • (2001) Cancer Res , vol.61 , pp. 5850-56
    • Dutoit, V.1    Rubio-Godoy, V.2    Dietrich, P.Y.3
  • 133
    • 0035870284 scopus 로고    scopus 로고
    • Tumor cells regulate the lytic activity of tumor-specific cytotoxic t lymphocytes by modulating the inhibitory natural killer receptor function
    • Gati A Guerra N Giron-Michel J et al. Tumor cells regulate the lytic activity of tumor-specific cytotoxic t lymphocytes by modulating the inhibitory natural killer receptor function. Cancer Res. 2001 61 3240 44.
    • (2001) Cancer Res , vol.61 , pp. 3240-44
    • Gati, A.1    Guerra, N.2    Giron-Michel, J.3
  • 134
    • 0242694876 scopus 로고    scopus 로고
    • CD158 receptor controls cytotoxic T-lymphocyte susceptibility to tumor-mediated activation-induced cell death by interfering with Fas signaling
    • Gati A Guerra N Gaudin C et al. CD158 receptor controls cytotoxic T-lymphocyte susceptibility to tumor-mediated activation-induced cell death by interfering with Fas signaling. Cancer Res. 2003 63 7475 82.
    • (2003) Cancer Res , vol.63 , pp. 7475-82
    • Gati, A.1    Guerra, N.2    Gaudin, C.3
  • 135
    • 0842325739 scopus 로고    scopus 로고
    • PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells
    • Blank C Brown I Peterson AC et al. PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells. Cancer Res. 2004 64 1140 45.
    • (2004) Cancer Res , vol.64 , pp. 1140-45
    • Blank, C.1    Brown, I.2    Peterson, A.C.3
  • 136
    • 0035869583 scopus 로고    scopus 로고
    • Absence of CTLA-4 lowers the activation threshold of primed CD8+ TCR-transgenic T cells: Lack of correlation with Src homology domain 2-containing protein tyrosine phosphatase
    • Gajewski TF Fallarino F Fields PE Rivas F Alegre ML. Absence of CTLA-4 lowers the activation threshold of primed CD8+ TCR-transgenic T cells: lack of correlation with Src homology domain 2-containing protein tyrosine phosphatase. J. Immunol. 2001 166 3900 907.
    • (2001) J. Immunol , vol.166 , pp. 3900-907
    • Gajewski, T.F.1    Fallarino, F.2    Fields, P.E.3    Rivas, F.4    Alegre, M.L.5
  • 137
    • 0033989570 scopus 로고    scopus 로고
    • Memory CD8 T lymphocytes express inhibitory MHC-specific Ly49 receptors
    • Coles MC McMahon CW Takizawa H Raulet DH. Memory CD8 T lymphocytes express inhibitory MHC-specific Ly49 receptors. Eur. J. Immunol. 2000 30 236 44.
    • (2000) Eur. J. Immunol , vol.30 , pp. 236-44
    • Coles, M.C.1    McMahon, C.W.2    Takizawa, H.3    Raulet, D.H.4
  • 138
    • 0034008510 scopus 로고    scopus 로고
    • Regulation of T cell function by NK cell receptors for classical MHC class I molecules
    • Ugolini S Vivier E. Regulation of T cell function by NK cell receptors for classical MHC class I molecules. Curr. Opin. Immunol. 2000 12 295 300.
    • (2000) Curr. Opin. Immunol , vol.12 , pp. 295-300
    • Ugolini, S.1    Vivier, E.2
  • 139
    • 0034927194 scopus 로고    scopus 로고
    • PD-1: An inhibitory immunoreceptor involved in peripheral tolerance
    • Nishimura H Honjo T. PD-1: an inhibitory immunoreceptor involved in peripheral tolerance. Trends Immunol. 2001 22 265 8.
    • (2001) Trends Immunol , vol.22 , pp. 265-8
    • Nishimura, H.1    Honjo, T.2
  • 140
    • 0030962059 scopus 로고    scopus 로고
    • Characterization of an antigen that is recognized on a melanoma showing partial HLA loss by CTL expressing an NK inhibitory receptor
    • Ikeda H Lethe B Lehmann F et al. Characterization of an antigen that is recognized on a melanoma showing partial HLA loss by CTL expressing an NK inhibitory receptor. Immunity 1997 6 199 208.
    • (1997) Immunity , vol.6 , pp. 199-208
    • Ikeda, H.1    Lethe, B.2    Lehmann, F.3
  • 141
    • 0034812048 scopus 로고    scopus 로고
    • Lack of tumor recognition by hTERT peptide 540-548-specific CD8(+) T cells from melanoma patients reveals inefficient antigen processing
    • Ayyoub M Migliaccio M Guillaume P et al. Lack of tumor recognition by hTERT peptide 540-548-specific CD8(+) T cells from melanoma patients reveals inefficient antigen processing. Eur. J. Immunol. 2001 31 2642 51.
    • (2001) Eur. J. Immunol , vol.31 , pp. 2642-51
    • Ayyoub, M.1    Migliaccio, M.2    Guillaume, P.3
  • 142
    • 18744373312 scopus 로고    scopus 로고
    • Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma
    • Romero P Valmori D Pittet MJ et al. Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma. Immunol. Rev. 2002 188 81 96.
    • (2002) Immunol. Rev , vol.188 , pp. 81-96
    • Romero, P.1    Valmori, D.2    Pittet, M.J.3
  • 143
    • 0037047079 scopus 로고    scopus 로고
    • Cytotoxic T lymphocytes directed against a tumor-specific mutated antigen display similar HLA tetramer binding but distinct functional avidity and tissue distribution
    • Echchakir H Dorothee G Vergnon I Menez J Chouaib S Mami-Chouaib F. Cytotoxic T lymphocytes directed against a tumor-specific mutated antigen display similar HLA tetramer binding but distinct functional avidity and tissue distribution. Proc. Natl Acad. Sci. USA 2002 99 9358 63.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 9358-63
    • Echchakir, H.1    Dorothee, G.2    Vergnon, I.3    Menez, J.4    Chouaib, S.5    Mami-Chouaib, F.6
  • 145
    • 0033559238 scopus 로고    scopus 로고
    • Modulation of proteasomal activity required for the generation of a cytotoxic T lymphocyte-defined peptide derived from the tumor antigen MAGE-3
    • Valmori D Gileadi U Servis C et al. Modulation of proteasomal activity required for the generation of a cytotoxic T lymphocyte-defined peptide derived from the tumor antigen MAGE-3. J. Exp. Med. 1999 189 895 906.
    • (1999) J. Exp. Med , vol.189 , pp. 895-906
    • Valmori, D.1    Gileadi, U.2    Servis, C.3
  • 146
    • 0037242017 scopus 로고    scopus 로고
    • Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I
    • Reits E Griekspoor A Neijssen J et al. Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I. Immunity 2003 18 97 108.
    • (2003) Immunity , vol.18 , pp. 97-108
    • Reits, E.1    Griekspoor, A.2    Neijssen, J.3
  • 147
    • 0033118158 scopus 로고    scopus 로고
    • Specificity of the proteasome and the TAP transporter
    • Uebel S Tampe R. Specificity of the proteasome and the TAP transporter. Curr. Opin. Immunol. 1999 11 203 8.
    • (1999) Curr. Opin. Immunol , vol.11 , pp. 203-8
    • Uebel, S.1    Tampe, R.2
  • 148
    • 1842785206 scopus 로고    scopus 로고
    • A major role for TPPII in trimming proteasomal degradation products for MHC class I antigen presentation
    • Reits E Neijssen J Herberts C et al. A major role for TPPII in trimming proteasomal degradation products for MHC class I antigen presentation. Immunity 2004 20 495 506.
    • (2004) Immunity , vol.20 , pp. 495-506
    • Reits, E.1    Neijssen, J.2    Herberts, C.3
  • 149
    • 0035796461 scopus 로고    scopus 로고
    • Discrete cleavage motifs of constitutive and immunoproteasomes revealed by quantitative analysis of cleavage products
    • Toes RE Nussbaum AK Degermann S et al. Discrete cleavage motifs of constitutive and immunoproteasomes revealed by quantitative analysis of cleavage products. J. Exp. Med. 2001 194 1 12.
    • (2001) J. Exp. Med , vol.194 , pp. 1-12
    • Toes, R.E.1    Nussbaum, A.K.2    Degermann, S.3
  • 150
    • 0034698738 scopus 로고    scopus 로고
    • Differential influence on cytotoxic T lymphocyte epitope presentation by controlled expression of either proteasome immunosubunits or PA28
    • van Hall T Sijts A Camps M et al. Differential influence on cytotoxic T lymphocyte epitope presentation by controlled expression of either proteasome immunosubunits or PA28. J. Exp. Med. 2000 192 483 94.
    • (2000) J. Exp. Med , vol.192 , pp. 483-94
    • Van Hall, T.1    Sijts, A.2    Camps, M.3
  • 151
    • 0037128172 scopus 로고    scopus 로고
    • The production of a new MAGE-3 peptide presented to cytolytic T lymphocytes by HLA-B40 requires the immunoproteasome
    • Schultz ES Chapiro J Lurquin C et al. The production of a new MAGE-3 peptide presented to cytolytic T lymphocytes by HLA-B40 requires the immunoproteasome. J. Exp. Med. 2002 195 391 9.
    • (2002) J. Exp. Med , vol.195 , pp. 391-9
    • Schultz, E.S.1    Chapiro, J.2    Lurquin, C.3
  • 152
    • 0033980648 scopus 로고    scopus 로고
    • Processing of some antigens by the standard proteasome but not by the immunoproteasome results in poor presentation by dendritic cells
    • Morel S Levy F Burlet-Schiltz O et al. Processing of some antigens by the standard proteasome but not by the immunoproteasome results in poor presentation by dendritic cells. Immunity 2000 12 107 17.
    • (2000) Immunity , vol.12 , pp. 107-17
    • Morel, S.1    Levy, F.2    Burlet-Schiltz, O.3
  • 153
    • 0037089678 scopus 로고    scopus 로고
    • Link between organ-specific antigen processing by 20S proteasomes and CD8(+) T cell-mediated autoimmunity
    • Kuckelkorn U Ruppert T Strehl B et al. Link between organ-specific antigen processing by 20S proteasomes and CD8(+) T cell-mediated autoimmunity. J. Exp. Med. 2002 195 983 90.
    • (2002) J. Exp. Med , vol.195 , pp. 983-90
    • Kuckelkorn, U.1    Ruppert, T.2    Strehl, B.3
  • 154
    • 4344644908 scopus 로고    scopus 로고
    • High frequency of functionally active Melan-a-specific T cells in a patient with progressive immunoproteasome-deficient melanoma
    • Meidenbauer N Zippelius A Pittet MJ et al. High frequency of functionally active Melan-a-specific T cells in a patient with progressive immunoproteasome-deficient melanoma. Cancer Res. 2004 64 6319 26.
    • (2004) Cancer Res , vol.64 , pp. 6319-26
    • Meidenbauer, N.1    Zippelius, A.2    Pittet, M.J.3
  • 155
    • 1142269466 scopus 로고    scopus 로고
    • Immune recognition of a human renal cancer antigen through post-translational protein splicing
    • Hanada K Yewdell JW Yang JC. Immune recognition of a human renal cancer antigen through post-translational protein splicing. Nature 2004 427 252 6.
    • (2004) Nature , vol.427 , pp. 252-6
    • Hanada, K.1    Yewdell, J.W.2    Yang, J.C.3
  • 156
    • 2142644458 scopus 로고    scopus 로고
    • An antigenic peptide produced by peptide splicing in the proteasome
    • Vigneron N Stroobant V Chapiro J et al. An antigenic peptide produced by peptide splicing in the proteasome. Science 2004 304 587 90.
    • (2004) Science , vol.304 , pp. 587-90
    • Vigneron, N.1    Stroobant, V.2    Chapiro, J.3
  • 157
    • 22344456827 scopus 로고    scopus 로고
    • Alpha v beta3-dependent cross-presentation of matrix metalloproteinase-2 by melanoma cells gives rise to a new tumor antigen
    • Godefroy E Moreau-Aubry A Diez E Dreno B Jotereau F Guilloux Y. alpha v beta3-dependent cross-presentation of matrix metalloproteinase-2 by melanoma cells gives rise to a new tumor antigen. J. Exp. Med. 2005 202 61 72.
    • (2005) J. Exp. Med , vol.202 , pp. 61-72
    • Godefroy, E.1    Moreau-Aubry, A.2    Diez, E.3    Dreno, B.4    Jotereau, F.5    Guilloux, Y.6
  • 158
    • 17844385106 scopus 로고    scopus 로고
    • The role of the proteasome in generating cytotoxic T-cell epitopes: Insights obtained from improved predictions of proteasomal cleavage
    • Nielsen M Lundegaard C Lund O Kesmir C. The role of the proteasome in generating cytotoxic T-cell epitopes: insights obtained from improved predictions of proteasomal cleavage. Immunogenetics 2005 57 33 41.
    • (2005) Immunogenetics , vol.57 , pp. 33-41
    • Nielsen, M.1    Lundegaard, C.2    Lund, O.3    Kesmir, C.4
  • 159
    • 23844528191 scopus 로고    scopus 로고
    • An integrative approach to CTL epitope prediction: A combined algorithm integrating MHC class I binding, TAP transport efficiency, and proteasomal cleavage predictions
    • Larsen MV Lundegaard C Lamberth K et al. An integrative approach to CTL epitope prediction: a combined algorithm integrating MHC class I binding, TAP transport efficiency, and proteasomal cleavage predictions. Eur. J. Immunol. 2005 35 2295 303.
    • (2005) Eur. J. Immunol , vol.35 , pp. 2295-303
    • Larsen, M.V.1    Lundegaard, C.2    Lamberth, K.3
  • 161
    • 2442680269 scopus 로고    scopus 로고
    • Transfection of RNA encoding tumor antigens following maturation of dendritic cells leads to prolonged presentation of antigen and the generation of high-affinity tumor-reactive cytotoxic T lymphocytes
    • Liao X Li Y Bonini C et al. Transfection of RNA encoding tumor antigens following maturation of dendritic cells leads to prolonged presentation of antigen and the generation of high-affinity tumor-reactive cytotoxic T lymphocytes. Mol. Ther. 2004 9 757 64.
    • (2004) Mol. Ther , vol.9 , pp. 757-64
    • Liao, X.1    Li, Y.2    Bonini, C.3
  • 162
    • 2442689202 scopus 로고    scopus 로고
    • Messenger RNA-electroporated dendritic cells presenting MAGE-A3 simultaneously in HLA class I and class II molecules
    • Bonehill A Heirman C Tuyaerts S et al. Messenger RNA-electroporated dendritic cells presenting MAGE-A3 simultaneously in HLA class I and class II molecules. J. Immunol. 2004 172 6649 57.
    • (2004) J. Immunol , vol.172 , pp. 6649-57
    • Bonehill, A.1    Heirman, C.2    Tuyaerts, S.3
  • 163
    • 0031051901 scopus 로고    scopus 로고
    • Anti-melanoma cytotoxic T lymphocytes (CTL) recognize numerous antigenic peptides having 'self' sequences: Autoimmune nature of the anti-melanoma CTL response
    • Tsomides TJ Reilly EB Eisen HN. Anti-melanoma cytotoxic T lymphocytes (CTL) recognize numerous antigenic peptides having 'self' sequences: autoimmune nature of the anti-melanoma CTL response. Int. Immunol. 1997 9 327 38.
    • (1997) Int. Immunol , vol.9 , pp. 327-38
    • Tsomides, T.J.1    Reilly, E.B.2    Eisen, H.N.3
  • 164
    • 0033847263 scopus 로고    scopus 로고
    • Identification of tumor-associated MHC class I ligands by a novel T cell-independent approach
    • Schirle M Keilholz W Weber B et al. Identification of tumor-associated MHC class I ligands by a novel T cell-independent approach. Eur. J. Immunol. 2000 30 2216 25.
    • (2000) Eur. J. Immunol , vol.30 , pp. 2216-25
    • Schirle, M.1    Keilholz, W.2    Weber, B.3
  • 165
    • 1542267730 scopus 로고    scopus 로고
    • The Tubingen approach: Identification, selection, and validation of tumor-associated HLA peptides for cancer therapy
    • Singh-Jasuja H Emmerich NP Rammensee HG. The Tubingen approach: identification, selection, and validation of tumor-associated HLA peptides for cancer therapy. Cancer Immunol. Immunother. 2004 53 187 195.
    • (2004) Cancer Immunol. Immunother , vol.53 , pp. 187-195
    • Singh-Jasuja, H.1    Emmerich, N.P.2    Rammensee, H.G.3


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