Computational analysis and experimental validation of tumor-associated alternative RNA splicing in human cancer

Cancer Research

Volumn 63, Issue 3, 2003, Pages 655-657

  Wang, Zhining ^a   Lo, H Shuen ^a   Yang, Howard ^a   Gere, Sheryl ^a   Hu, Ying ^a   Buetow, Kenneth H ^a   Lee, Maxwell P ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALGORITHM; ALTERNATIVE RNA SPLICING; ARTICLE; CANCER; EXPRESSED SEQUENCE TAG; GENOME; HUMAN; HUMAN TISSUE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; VALIDATION PROCESS;

ALGORITHMS; ALTERNATIVE SPLICING; COMPUTATIONAL BIOLOGY; DATABASES, NUCLEIC ACID; EXPRESSED SEQUENCE TAGS; GENETIC MARKERS; GENOME, HUMAN; HUMANS; LIVER NEOPLASMS; NEOPLASMS; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 0037310045     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Hastings, M. L., and Krainer, A. R. Pre-mRNA splicing in the new millennium. Curr. Opin. Cell Biol., 13: 302-309, 2001.
2. Early, P., Rogers, J., Davis, M., Calame, K., Bond, M., Wall, R., and Hood, L. Two mRNAs can be produced from a single immunoglobulin mu gene by alternative RNA processing pathways. Cell, 20: 313-319, 1980.
3. Nagoshi, R. N., McKeown, M., Burtis, K. C., Belote, J. M., and Baker, B. S. The control of alternative splicing at genes regulating sexual differentiation in D, melanogaster. Cell, 53: 229-236, 1988.
4. Huang, Y. H., Chen, Y. T., Lai, J. J., Yang, S. T., and Yang, U. C. PALS db: putative alternative splicing database. Nucleic Acids Res., 30: 186-190, 2002.
5. Modrek, B., Resch, A., Grasso, C., and Lee, C. Genome-wide detection of alternative splicing in expressed sequences of human genes. Nucleic Acids Res., 29: 2850-2859, 2001.
6. Brett, D., Hanke, J., Lehmann, G., Haase, S., Delbruck, S., Krueger, S., Reich, J., and Bork, P. EST comparison indicates 38% of human mRNAs contain possible alternative splice forms. FEBS Lett., 474: 83-86, 2000.
7. Mironov, A. A., Fickett, J. W., and Gelfand, M. S. Frequent alternative splicing of human genes. Genome Res., 9: 1288-1293, 1999.
8. Xie, H., Zhu, W., Wasserman, A., Grebinskiy, V., Olson, A., and Mintz, L. Computational analysis of alternative splicing using EST tissue information. Genomics, 80: 326-330, 2002.
9. Stimpfl, M., Tong, D., Fasching, B., Schuster, E., Obermair, A., Leodolter, S., and Zeillinger, R. Vascular endothelial growth factor splice variants and their prognostic value in breast and ovarian cancer. Clin. Cancer Res., 8: 2253-2259, 2002.
10. Adams, M., Jones, J. L., Walker, R. A., Pringle, J. H., and Bell, S. C. Changes in tenascin-C isoform expression in invasive and preinvasive breast disease. Cancer Res., 62: 3289-3297, 2002.
11. Lee, M. P., and Feinberg, A. P. Aberrant splicing but not mutations of TSG101 in human breast cancer. Cancer Res., 57: 3131-3134, 1997.
12. Rozen, S., and Skaletsky, H. Primer3 on the WWW for general users and for biologist programmers. Methods Mol. Biol., 132: 365-386, 2000.
13. Ewing, B., Hillier, L., Wendl, M. C., and Green, P. Base-calling of automated sequencer traces using phred. I. Accuracy assessment. Genome Res., 8: 175-185, 1998.
14. Kinzler, K. W., and Vogelstein, B. Lessons from hereditary colorectal cancer. Cell, 87: 159-170, 1996.