Appropriate use of information on family history of disease in recruitment for linkage analysis studies

Annals of Human Genetics

Volumn 70, Issue 3, 2006, Pages 360-371

  Wallace, Chris ^a   Clayton, D G ^b  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; CORRELATION ANALYSIS; FAMILY HISTORY; GENE LOCUS; GENETIC DISORDER; GENETIC HETEROGENEITY; GENETIC LINKAGE; GENETIC PREDISPOSITION; GENETIC RISK; GENETIC TRAIT; GENOTYPE; HUMAN; MATHEMATICAL COMPUTING; MEDICAL INFORMATION; PHENOTYPE; POPULATION GENETICS; PRIORITY JOURNAL; PROBABILITY; SAMPLE SIZE; SIBLING;

FAMILY HEALTH; HUMANS; LINKAGE (GENETICS); MEDICAL HISTORY TAKING; PATIENT SELECTION; SAMPLE SIZE; VARIATION (GENETICS);

EID: 33645748772     PISSN: 00034800     EISSN: 14691809     Source Type: Journal    
DOI: 10.1111/j.1529-8817.2005.00233.x     Document Type: Article

References (33)

1. Abkevich, V., Camp, N., Hensel, C. et al. (2003) Predisposition locus for major depression at chromosome 12q22-12q23.2. Am J Hum Genet 73, 1271 - 1281.
2. Badner, J. A., Gershon, E. S. & Goldin, L. R. (1998) Optimal ascertainment strategies to detect linkage to common disease alleles. Am J Hum Genet 63, 880-888.
3. Becker, K. (2004) The common variants/multiple disease hypothesis of common complex genetic disorders. Medical Hypotheses 62, 309-317.
4. Blackwelder, W. & Elston, R. (1985) A comparison of sib-pair linkage tests for disease susceptibility loci. Genet Epidemiol 2, 85-97.
5. Chakravarti, A. (1999) Population genetics? making sense out of sequence. Nat Genet 21, 56-60.
6. Corder, E., Saunders, A., Strittmatter, W. et al. (1993) Gene dose of apolipoprotein-e type-4 allele and the risk of alzheimers-disease in late-onset families. Science 261, 921-923.
7. Edwards, S., Meitz, J., Hope, Q. et al. (2003) Results of a genome-wide linkage analysis in prostate cancer families ascertained through the actane consortium. Prostate 57, 270-279.
8. Fullerton, S., Clark, A., Weiss, K. et al. (2000) Apolipoprotein e variation at the sequence haplotype level: Implications for the origin and maintenance of a major human polymorphism. Am J Hum Genet 67, 881-900.
9. Ge, D., Yang, W., Huang, J. et al. (2003) Linkage analysis of 2q14-q23 and 5q32 with blood pressure quantitative traits in chinese sib pairs. J Hypertens 21, 305-310.
10. Gillanders, E., Juo, S., Holland, E. et al. (2003) Localization of a novel melanoma susceptibility locus to 1p22. Am J Hum Genet 73, 301-313.
11. Goddard, K. A., Goode, E. L., Rozek, L. S. et al. (1999) Impact of family structure on the power of linkage tests using sib-pair methods. Genet Epidemiol 17, S575-9.
12. Hodge, S. (1981) Some epistatic 2-locus models of disease. 1. relative risks and identity-by-descent distributions in affected sib pairs. Am J Hum Genet 33, 381-395.
13. Hugot, J. P., Chamaillard, M., Zouali, H. et al. (2001) Association of nod2 leucine-rish repeat variants with susceptibility to crohn's disease. Nature 411, 599-603.
14. Karigl, G. (1982) A mathematical approach to multiple genetic relationships. Theor Popul Biol 21, 379-393.
15. Li, W. & Reich, J. (2000) A complete enumeration and classification of two-locus disease models. Hum Hered 50, 334-349.
16. Li, Z. & Gastwirth, J. (2004) On the power of affected relative pair designs for linkage studies. Ann Human Genet 68, 65-65.
17. McCarthy, M. I., Kruglyak, L. & Lander, E. S. (1998) Sib-pair collection strategies for complex diseases. Genet Epidemiol 15, 317-340.
18. Morrison, A., Brown, A., Kardia, S. et al. (2003) Evaluating the context-dependent effect of family history of stroke in a genome scan for hypertension. Stroke 34, 1170-1175.
19. Ogura, Y., Bonen, D. K., Inohara, N. et al. (2001) A frameshift muatation in nod2 associated with susceptibility to Crohn's disease. Nature 411, 603-606.
20. Pankratz, N., Nichols, W., Uniacke, S. et al. (2003) Genome-wide linkage analysis and evidence of gene-by-gene interactions in a sample of 362 multiplex parkinson disease families. Hum Mol Genet 12, 2599-2608.
21. Pritchard, J. & Cox, N. (2002) The allelic architecture of human disease genes: Common disease - common variant... or not ? Hum Mol Genet 11, 2417 - 2423.
22. Reich, D. & Lander, E. (2001) On the allelic spectrum of human disease. Trends Genet 17, 502-510.
23. Risch, N. (1990a) Linkage strategies for genetically complex traits I. Multilocous models. Am J Hum Genet 42, 222-228.
24. Risch, N. (1990b) Linkage strategies for genetically complex traits II. The power of affected relative pairs. Am J Hum Genet 42, 229-241.
25. Risch, N. (2001) Implications of multilocus inheritance for gene-disease association studies. Theor Popul Biol 60, 215-220.
26. Risch, N. & Merikangas, K. (1996) The future of genetic studies of complex human diseases. Science 273, 1516-7.
27. Rybicki, B. A. & Elston, R. C. (2000) The relationship between the sibling recurrence-risk ratio and genotype relative risk. Am J Hum Genet 66, 593-604.
28. Sham, P. C. (1998) Statistics in human genetics. arnold.
29. Teng, J. & Risch, N. (1999) The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases. ii. individual genotyping. Genome Res 9, 234-241.
30. Terwilliger, J., Haghighi, F., Hiekkalinna, T. et al. (2002) A bias-ed assessment of the use of snps in human complex traits. Curr Opin Genet Dev 12, 726-734.
31. Thompson, E. (1974) Gene identites and multiple relationships. Biometrics 30, 667-680.
32. Wang, W. & Pike, N. (2004) The allelic spectra of common diseases may resemble the allelic spectrum of the full genome. Medical Hypotheses 63, 748-751.
33. Wright, A., Carothers, A. & Pirastu, M. (1999) Population choice in mapping genes for complex diseases. Nature Genet 23, 397-404.