Implications of multilocus inheritance for gene-disease association studies

Theoretical Population Biology

Volumn 60, Issue 3, 2001, Pages 215-220

  Risch, Neil ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DIVISION OF RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASE; GENETICS; HERITABILITY; STATISTICAL ANALYSIS;

ALLELE; ARTICLE; BIOLOGICAL MODEL; CHROMOSOME MAP; GENETIC LINKAGE; GENETIC MARKER; GENETIC PREDISPOSITION; GENOTYPE; HUMAN; PEDIGREE; RISK;

ALLELES; CHROMOSOME MAPPING; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LINKAGE (GENETICS); MODELS, GENETIC; PEDIGREE; RISK;

EID: 0035528925     PISSN: 00405809     EISSN: None     Source Type: Journal    
DOI: 10.1006/tpbi.2001.1538     Document Type: Article

References (15)

1. Variations on a theme: Cataloging human DNA sequence variation
2. Initial sequencing and analysis of the human genome
3. Prospects for whole-genome linkage disequilibrium mapping of common disease genes
4. Demographic history and linkage disequilibrium in human populations
5. The new genomics: Global views of biology
6. Allelic association between marker loci
7. The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases I. DNA pooling
8. The future of genetic studies of complex human diseases
9. Genotype relative risks: Methods for the design and analysis of candidate gene association studies
10. Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
11. The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases. II. Individual genotyping
12. The sequence of the human genome
13. Population stratification in epidemiologic studies of common genetic variants and cancer: Quantification of bias
14. Population choice in mapping genes for complex diseases