High glucose stimulates expression of p27(Kip1) in cultured mouse mesangial cells: Relationship to hypertrophy

American Journal of Physiology - Renal Physiology

Volumn 273, Issue 3 42-3, 1997, Pages

  Wolf, Gunter ^a,c   Schroeder, Regine ^a   Ziyadeh, Fuad N ^b   Thaiss, Friedrich ^a   Zahner, Gunther ^a   Stahl, Rolf A K ^a  

^a UNIVERSITY OF HAMBURG   (Germany)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Cell cycle progression; Cyclin dependent kinases; Diabetic nephropathy

Indexed keywords

OLIGONUCLEOTIDE;

ANIMAL CELL; ARTICLE; CELL CYCLE G1 PHASE; CELL HYPERPLASIA; CELL PROLIFERATION; DIABETIC NEPHROPATHY; GENE EXPRESSION REGULATION; HYPERGLYCEMIA; MESANGIUM; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN SYNTHESIS REGULATION;

EID: 0030817707     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.1997.273.3.f348     Document Type: Article

References (35)

1. Adler, S. Structure-function relationships associated with extracellular matrix alterations in diabetic glomerulopathy. J. Am. Soc. Nephrol. 5: 1165-1172, 1994.
2. Bennett, C. F., M. Y. Chiang, H. Chan, J. E. Shoemaker, and C. K. Mirabelli. Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides. Mol. Pharmacol. 41: 1023-1033, 1992.
3. Brown, E. J., and S. L. Schreiber. A signaling pathway to translational control. Cell 86: 517-520, 1996.
4. Kip1 for restriction point control of the fibroblast cell cycle. Science 272: 877-880, 1996.
5. Cosio, F. G. Effects of high glucose concentrations on human mesangial cell proliferation. J. Am. Soc. Nephrol. 5: 1600-1609, 1995.
6. DeRubertis, F. R., and P. A. Craven. Activation of protein kinase C in glomerular cells in diabetes. Mechanism and potential links to the pathogenesis of diabetic glomerulopathy. Diabetes 43: 1-8, 1994.
7. Kip1. Cell Growth Differ. 6: 915-925, 1995.
8. Kip1-deficient mice. Cell 85: 733-744, 1996.
9. Grana, X., and E. P. Reddy. Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cylin-dependent kinase inhibitors (CKIs). Oncogene 11: 211-229, 1995.
10. Kip1 accumulation during the cell cycle. Science 271: 1861-1864, 1996.
11. Kawamoto, S., and H. Hidaka. 1-(5-Isoquinolinesulfonyl)-2-methylpiperazine (H-7) is a selective inhibitor of protein kinase C in rabbit platelets. Biochem. Biophys. Res. Commun. 125: 258-264, 1984.
12. Kip1. Cell 85: 721-732, 1996.
13. Kreisberg, J. L., R. A. Radnick, S. H. Ayo, J. A. Garoni, and P. Saikumar. High glucose elevates c-fos and c-jun transcripts and proteins in mesangial cell cultures. Kidney Int. 46: 105-112, 1994.
14. Liu, B., and P. A. Preisig. TGFβ-mediated conversion of EGF-induced hyperplasia to hypertrophy involves cyclin E, but not cyclin D kinase regulation, and is dependent on cells being in a confluent state (Abstract). J. Am. Soc. Nephrol. 7: 1661, 1996.
15. Mauer, S. M., M. W. Steffes, E. N. Ellis, D. E. R. Sutherland, D. M. Brown, and F. C. Goetz. Structural-functional relationships in diabetic nephropathy. J. Clin. Invest. 74: 1143-1155, 1984.
16. Mogyorosi, A., and F. N. Ziyadeh. Update on pathogenesis, markers and management of diabetic nephropathy. Curr. Opin. Nephrol. Hypertens. 5: 243-253, 1996.
17. Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituary tumors. Cell 85: 707-720, 1996.
18. Peter, M., and I. Herskowitz. Joining the complex: cyclin-dependent kinase inhibitory proteins and the cell cycle. Cell 78: 181-184, 1994.
19. Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes Dev. 8: 9-22, 1994.
20. Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78: 59-66, 1994.
21. Shankland, S. J., C. Hugo, S. R. Coats, M. Nangaku, R. H. Pichler, K. L. Godon, J. Pippin, J. M. Roberts, W. G. Couser, and R. J. Johnson. Changes in cell-cycle protein expression during experimental mesangial proliferative glomerulonephritis. Kidney Int. 50: 1230-1239, 1996.
22. Kip1 (p27) regulates the mesangial cell (MC) response to PDGF and bFGF, but not TGF-β1 (Abstract). J. Am. Soc. Nephrol. 7: 1665, 1996.
23. Sharma, K., and F. N. Ziyadeh. The emerging role of transforming growth factor-β in kidney diseases. Am. J. Physiol. 266 (Renal Fluid Electrolyte Physiol. 35): F829-F842, 1994.
24. Slingerland, J. M., L. Hengst, C. H. Pan, D. Alexander, M. P. Stampfer, and S. I. Reed. A novel inhibitor of cylin-cdk activity detected in transforming growth factor β-arrested epithelial cells. Mol. Cell Biol. 14: 3683-3694, 1994.
25. Soss, T. J., H. Kiyokawa, J. S. Yan, M. S. Rubin, A. Giordano, A. DeBlasio, S. Bottega, B. Wing, J. Mendelsohn, and A. Koff. Formation of p27-CDK complexes during the human mitotic cell cycle. Cell Growth Differ. 7: 135-146, 1996.
26. Stein, C. A., and Y. C. Cheng. Antisense oligonucleotides as therapeutic agents: is the bullet really magical? Science 261: 1004-1012, 1993.
27. Stoscheck, C. M. Quantitation of protein. Methods Enzymol. 182: 50-68, 1990.
28. Toyoshima, H., and T. Hunter. p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell 78: 67-74, 1994.
29. Wolf, G., E. Mueller, R. A. K. Stahl, and F. N. Ziyadeh. Angiotensin II-induced hypertrophy of cultured murine proximal tubular cells is mediated by endogenous transforming growth factor-β. J. Clin. Invest. 92: 1366-1372, 1993.
30. Wolf, G., K. Sharma, Y. Chen, M. Ericksen, and F. N. Ziyadeh. High glucose-induced proliferation in mesangial cells is reversed by autocrine TGF-β. Kidney Int. 42: 647-656, 1992.
31. Kip1. Kidney Int. 50: 2112-2119, 1996.
32. Wolf, G., and F. Thaiss. Hyperglycaemia-pathophysiological aspects at the cellular level. Nephrol. Dial. Transplant. 10:1109-1112, 1995.
33. Xia, P., T. Inoguchi, T. S. Kern, R. L. Engerman, P. J. Oates, and G. L. King. Characterization of the mechanism for the chronic activation of diacyclycerol-protein kinase C pathway in diabetes and hyperglycemia. Diabetes 43: 1122-1129, 1994.
34. Young, B. A., R. J. Johnson, C. E. Alpers, E. Eng, K. Gordon, J. Floege, and W. G. Couser. Cellular events in the evolution of experimental diabetic nephropathy. Kidney Int. 47: 935-944, 1995.
35. Ziyadeh, F. N., K. Sharma, M. Ericksen, and G. Wolf. Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor-β. J. Clin. Invest. 93: 536-542, 1994.