Isoform switching of type IV collagen is developmentally arrested in X- linked Aport syndrome leading to increased susceptibility of renal basement membranes to endoproteolysis

Journal of Clinical Investigation

Volumn 99, Issue 10, 1997, Pages 2470-2478

  Kalluri, Raghuram ^a   Shield III, Charles F ^b   Todd, Parvin ^c   Hudson, Billy G ^c   Neilson, Eric G ^a,d  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b Via Christi Rehabilitation Center   (United States)

^c UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Alport; basement membrane; kidney; proteases; type IV collagen

Indexed keywords

CATHEPSIN; COLLAGEN TYPE 4; COLLAGENASE; CYSTEINE;

ALPORT SYNDROME; ARTICLE; CONTROLLED STUDY; EMBRYO; GENETIC SUSCEPTIBILITY; GLOMERULUS BASEMENT MEMBRANE; GLOMERULUS FILTRATION; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN POLYMORPHISM; X CHROMOSOME LINKAGE;

EID: 0031000529     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119431     Document Type: Article

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