메뉴 건너뛰기




Volumn 16, Issue 2, 2006, Pages 125-131

The contribution of keratinocytes to the pathogenesis of atopic dermatitis

Author keywords

Atopic dermatitis; Chemokines; Cytokines; Epidermal differentiation; Epithelial cells; Keratinocytes; Serine proteinases

Indexed keywords

CERAMIDE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN E; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 13; INTERLEUKIN 4; RANTES; SERINE PROTEINASE; TRANSCRIPTION FACTOR;

EID: 33645581525     PISSN: 11671122     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (104)

References (64)
  • 2
    • 0034869373 scopus 로고    scopus 로고
    • Epidemiology, clinical features, and immunology of the "intrinsic" (non-IgE-mediated) type of atopic dermatitis (constitutional dermatitis)
    • Schmid-Grendelmeier P, Simon D, Simon HU, Akdis CA, Wüthrich B. Epidemiology, clinical features, and immunology of the "intrinsic" (non-IgE-mediated) type of atopic dermatitis (constitutional dermatitis). Allergy 2001; 56: 841-9.
    • (2001) Allergy , vol.56 , pp. 841-849
    • Schmid-Grendelmeier, P.1    Simon, D.2    Simon, H.U.3    Akdis, C.A.4    Wüthrich, B.5
  • 4
    • 24344448276 scopus 로고    scopus 로고
    • Stratum corneum defensive functions: An integrated view
    • Elias PM. Stratum corneum defensive functions: an integrated view. J Invest Dermatol 2005; 125: 183-200.
    • (2005) J Invest Dermatol , vol.125 , pp. 183-200
    • Elias, P.M.1
  • 5
    • 0038108805 scopus 로고    scopus 로고
    • A second step of chemotaxis after transendothelial migration: Keratinocytes undergoing apoptosis relase IFN-γ-inducible protein 10, monokine induced by IFN-γ, and IFN-γ-inducible α- chemoattractant for T cell chemotaxis toward epidermis in atopic dermatitis
    • Klunker S, Trautmann A, Akdis M, Verhagen J, Schmid-Grendelmeyer P, Blaser K, et al. A second step of chemotaxis after transendothelial migration: keratinocytes undergoing apoptosis relase IFN-γ-inducible protein 10, monokine induced by IFN-γ, and IFN-γ-inducible α- chemoattractant for T cell chemotaxis toward epidermis in atopic dermatitis. J Immunol 2003; 171: 1078-84.
    • (2003) J Immunol , vol.171 , pp. 1078-1084
    • Klunker, S.1    Trautmann, A.2    Akdis, M.3    Verhagen, J.4    Schmid-Grendelmeyer, P.5    Blaser, K.6
  • 8
    • 0034782362 scopus 로고    scopus 로고
    • The differential fate of cadherins during T cell-induced keratinocyte apoptosis leads to spongiosis in eczematous dermatitis
    • Trautmann A, Altznauer F, Akdis M, Simon HU, Disch R, Brocker EB, et al. The differential fate of cadherins during T cell-induced keratinocyte apoptosis leads to spongiosis in eczematous dermatitis. J Invest Dermatol 2001; 117: 927-34.
    • (2001) J Invest Dermatol , vol.117 , pp. 927-934
    • Trautmann, A.1    Altznauer, F.2    Akdis, M.3    Simon, H.U.4    Disch, R.5    Brocker, E.B.6
  • 11
    • 16844386596 scopus 로고    scopus 로고
    • Interleukin-4 suppresses the enhancement of ceramide synthesis and cutaneous permeability barrier functions induced by TNF-α and IFN-γ in human epidermis
    • Hatano Y, Terashi H, Arakawa S, Katagiri K. Interleukin-4 suppresses the enhancement of ceramide synthesis and cutaneous permeability barrier functions induced by TNF-α and IFN-γ in human epidermis. J Invest Dermatol 2005; 124: 786-92.
    • (2005) J Invest Dermatol , vol.124 , pp. 786-792
    • Hatano, Y.1    Terashi, H.2    Arakawa, S.3    Katagiri, K.4
  • 12
    • 0035546147 scopus 로고    scopus 로고
    • T-cell sub-populations in the development of atopic and contact allergy
    • Girolomoni G, Sebastiani S, Albanesi C, Cavani A. T-cell sub-populations in the development of atopic and contact allergy. Curr Opin Immunol 2001; 13: 733-7.
    • (2001) Curr Opin Immunol , vol.13 , pp. 733-737
    • Girolomoni, G.1    Sebastiani, S.2    Albanesi, C.3    Cavani, A.4
  • 14
    • 21344462840 scopus 로고    scopus 로고
    • Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects
    • Sicherer SH, Leung DYM. Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects. J Allergy Clin Immunol 2005; 116: 153-63.
    • (2005) J Allergy Clin Immunol , vol.116 , pp. 153-163
    • Sicherer, S.H.1    Leung, D.Y.M.2
  • 15
    • 0042661160 scopus 로고    scopus 로고
    • Ultraviolet A irradiation inhibits thymus and activation-regulated chemokine (TARC/CCL17) production by a human keratinocyte HaCaT cell line
    • Zheng X, Nakamura K, Tojo M, Akiba H, Oyama N, Nishibu A, et al. Ultraviolet A irradiation inhibits thymus and activation-regulated chemokine (TARC/CCL17) production by a human keratinocyte HaCaT cell line. Eur J Dermatol 2003; 13: 348-53.
    • (2003) Eur J Dermatol , vol.13 , pp. 348-353
    • Zheng, X.1    Nakamura, K.2    Tojo, M.3    Akiba, H.4    Oyama, N.5    Nishibu, A.6
  • 16
    • 0035003526 scopus 로고    scopus 로고
    • Keratinocytes from patients with atopic dermatitis and psoriasis show a different chemokine production profile in response to T cell-derived cytokines
    • Giustizieri ML, Mascia F, Frezzolini A, De Pità O, Chinni ML, Giannetti A, et al. Keratinocytes from patients with atopic dermatitis and psoriasis show a different chemokine production profile in response to T cell-derived cytokines. J Allergy Clin Immunol 2001; 107: 871-7.
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 871-877
    • Giustizieri, M.L.1    Mascia, F.2    Frezzolini, A.3    De Pità, O.4    Chinni, M.L.5    Giannetti, A.6
  • 17
    • 0034880508 scopus 로고    scopus 로고
    • Enhanced production or CC-chemokines (RANTES, MCP-1, MIP-1α, MIP-1β, and eotaxin) in patients with atopic dermatitis
    • Kaburagi Y, Shimada Y, Nagaoka T, Hasegawa M, Takehara K, Sato S. Enhanced production or CC-chemokines (RANTES, MCP-1, MIP-1α, MIP-1β, and eotaxin) in patients with atopic dermatitis. Arch Dermatol Res 2001; 293: 350-5.
    • (2001) Arch Dermatol Res , vol.293 , pp. 350-355
    • Kaburagi, Y.1    Shimada, Y.2    Nagaoka, T.3    Hasegawa, M.4    Takehara, K.5    Sato, S.6
  • 18
    • 0036170945 scopus 로고    scopus 로고
    • CCL27-CCR10 interactions regulate T cell-mediated skin inflammation
    • Homey B, Alenius H, Muller A, Soto H, Bowman EP, Yuan W, et al. CCL27-CCR10 interactions regulate T cell-mediated skin inflammation. Nat Med 2002; 8: 157-65.
    • (2002) Nat Med , vol.8 , pp. 157-165
    • Homey, B.1    Alenius, H.2    Muller, A.3    Soto, H.4    Bowman, E.P.5    Yuan, W.6
  • 19
    • 0346995201 scopus 로고    scopus 로고
    • Distinct patterns or gene expression in the skin lesions of atopic dermatitis and psoriasis: A gene microarray analysis
    • Nomura I, Boguniewicz GB, Darst MA, Travers JB, Leung DYM. Distinct patterns or gene expression in the skin lesions of atopic dermatitis and psoriasis: a gene microarray analysis. J Allergy Clin Immunol 2003; 112: 1195-202.
    • (2003) J Allergy Clin Immunol , vol.112 , pp. 1195-1202
    • Nomura, I.1    Boguniewicz, G.B.2    Darst, M.A.3    Travers, J.B.4    Leung, D.Y.M.5
  • 21
    • 6344241439 scopus 로고    scopus 로고
    • CC chemokine ligand 18, an atopic dermatitis-associated and dendritic cell-derived chemokine, is regulated by staphylococcal products and allergen exposure
    • Pivarcsi A, Gompert M, Dieu-Nosjean MC, Lauerma A, Kubitza R, Meller S, et al. CC chemokine ligand 18, an atopic dermatitis-associated and dendritic cell-derived chemokine, is regulated by staphylococcal products and allergen exposure. J Immunol 2004; 173: 5810-7.
    • (2004) J Immunol , vol.173 , pp. 5810-5817
    • Pivarcsi, A.1    Gompert, M.2    Dieu-Nosjean, M.C.3    Lauerma, A.4    Kubitza, R.5    Meller, S.6
  • 22
    • 0036547277 scopus 로고    scopus 로고
    • Expression of the C-C chemokine MIP-3α/CCL20 in human epidermis with impaired permeability barrier function
    • Schmuth M, Neyer S, Rainer C, Grassegger A, Fritsch P, Romani N, Heufler C. Expression of the C-C chemokine MIP-3α/CCL20 in human epidermis with impaired permeability barrier function. Exp Dermatol 2002; 11: 135-42.
    • (2002) Exp Dermatol , vol.11 , pp. 135-142
    • Schmuth, M.1    Neyer, S.2    Rainer, C.3    Grassegger, A.4    Fritsch, P.5    Romani, N.6    Heufler, C.7
  • 24
    • 0035529004 scopus 로고    scopus 로고
    • Engagement of the FceRI stimulates the production of IL-16 in atopic dermatitis
    • Reich K, Heine H, Hugo S, Blaschke V, Middel P, Kaser A, et al. Engagement of the FceRI stimulates the production of IL-16 in atopic dermatitis. J Immunol 2001; 167: 6321-9.
    • (2001) J Immunol , vol.167 , pp. 6321-6329
    • Reich, K.1    Heine, H.2    Hugo, S.3    Blaschke, V.4    Middel, P.5    Kaser, A.6
  • 25
    • 0035086113 scopus 로고    scopus 로고
    • Dendritic cells as a major source of macrophage-derived chemokine/CCL22 in vitro and in vivo
    • Vulcano M, Albanesi C, Stopacciaro A, Bagnati R, D'Amico G, Struyf S, et al. Dendritic cells as a major source of macrophage-derived chemokine/CCL22 in vitro and in vivo. Eur J Immunol 2001; 31: 812-22.
    • (2001) Eur J Immunol , vol.31 , pp. 812-822
    • Vulcano, M.1    Albanesi, C.2    Stopacciaro, A.3    Bagnati, R.4    D'Amico, G.5    Struyf, S.6
  • 26
    • 0036721609 scopus 로고    scopus 로고
    • Quantitative differences in chemokine receptor engagement generate diversity in integrin-dependent lymphocyte adhesion
    • D'Ambrosio D, Albanesi C, Lang R, Girolomoni G, Sinigaglia F, Laudanna C. Quantitative differences in chemokine receptor engagement generate diversity in integrin-dependent lymphocyte adhesion. J Immunol 2002; 169: 2303-12.
    • (2002) J Immunol , vol.169 , pp. 2303-2312
    • D'Ambrosio, D.1    Albanesi, C.2    Lang, R.3    Girolomoni, G.4    Sinigaglia, F.5    Laudanna, C.6
  • 27
    • 1142285210 scopus 로고    scopus 로고
    • Serum thymus and activation-regulated chemokine (TARC) and cutaneous T cell- Attracting chemokine (CTACK) levels in allergic diseases: TARC and ClACK are disease-specific markers for atopic dermatitis
    • Hijnen D, Bruin-Weller M, Oosting B, Lebre C, De Jong E, Bruijnzeel-Koomen C, Knol E. Serum thymus and activation-regulated chemokine (TARC) and cutaneous T cell- attracting chemokine (CTACK) levels in allergic diseases: TARC and ClACK are disease-specific markers for atopic dermatitis. J Allergy Clin Immunol 2004; 113: 334-40.
    • (2004) J Allergy Clin Immunol , vol.113 , pp. 334-340
    • Hijnen, D.1    Bruin-Weller, M.2    Oosting, B.3    Lebre, C.4    De Jong, E.5    Bruijnzeel-Koomen, C.6    Knol, E.7
  • 28
    • 20144387167 scopus 로고    scopus 로고
    • CCL1-CCR8 interactions: An axis mediating the recruitment of T cells and Langerhans-type dendritic cells to sites of atopic skin inflammation
    • Gompert M, Dieu-Nosjean MC, Winterberg F, Bünemann E, Kubitza RC, Da Cunha L, et al. CCL1-CCR8 interactions: an axis mediating the recruitment of T cells and Langerhans-type dendritic cells to sites of atopic skin inflammation. J Immunol 2005; 174: 5082-91.
    • (2005) J Immunol , vol.174 , pp. 5082-5091
    • Gompert, M.1    Dieu-Nosjean, M.C.2    Winterberg, F.3    Bünemann, E.4    Kubitza, R.C.5    Da Cunha, L.6
  • 29
    • 2342516024 scopus 로고    scopus 로고
    • Expression of fraktalkine and its receptor, CX3CR1, in atopic dermatitis: Possible contribution to skin inflammation
    • Echigo T, Hasegawa M, Shimada Y, Takehara K, Sato S. Expression of fraktalkine and its receptor, CX3CR1, in atopic dermatitis: possible contribution to skin inflammation. J Allergy Clin Immunol 2004; 113: 940-8.
    • (2004) J Allergy Clin Immunol , vol.113 , pp. 940-948
    • Echigo, T.1    Hasegawa, M.2    Shimada, Y.3    Takehara, K.4    Sato, S.5
  • 30
    • 0033762498 scopus 로고    scopus 로고
    • The EGF receptor - An essential regulator of multiple epidermal functions
    • Jost M, Kari C, Rodeck U. The EGF receptor - an essential regulator of multiple epidermal functions. Eur J Dermatol 2000; 10: 505-10.
    • (2000) Eur J Dermatol , vol.10 , pp. 505-510
    • Jost, M.1    Kari, C.2    Rodeck, U.3
  • 32
    • 0038545569 scopus 로고    scopus 로고
    • Chemokine receptors in asthma: Searching for the correct immune targets
    • Lukacs NW, Miller AL, Hogaboam CM. Chemokine receptors in asthma: searching for the correct immune targets. J Immunol 2003; 171: 11-5.
    • (2003) J Immunol , vol.171 , pp. 11-15
    • Lukacs, N.W.1    Miller, A.L.2    Hogaboam, C.M.3
  • 33
    • 0036961838 scopus 로고    scopus 로고
    • Epidermal growth factor receptor ligands and tumor necrosis factor-alpha coregulate chemokine expression in human keratinocytes
    • Pastore S, Mascia F, Mariani V, Girolomoni G. Epidermal growth factor receptor ligands and tumor necrosis factor-alpha coregulate chemokine expression in human keratinocytes. Ann N Y Acad Sci 2002; 973: 210-3.
    • (2002) Ann N Y Acad Sci , vol.973 , pp. 210-213
    • Pastore, S.1    Mascia, F.2    Mariani, V.3    Girolomoni, G.4
  • 34
    • 0038306878 scopus 로고    scopus 로고
    • Blockade of the EGF receptor induces a deranged chemokine expression in keratinocytes leading to enhanced skin inflammation
    • Mascia F, Mariani V, Girolomoni G, Pastore S. Blockade of the EGF receptor induces a deranged chemokine expression in keratinocytes leading to enhanced skin inflammation. Am J Pathol 2003; 163: 303-12.
    • (2003) Am J Pathol , vol.163 , pp. 303-312
    • Mascia, F.1    Mariani, V.2    Girolomoni, G.3    Pastore, S.4
  • 36
    • 0029922964 scopus 로고    scopus 로고
    • Immunomorphological and ultrastructural characterization of Langerhans cells and a novel, inflammatory dendritic epidermal cell (IDEC) population in lesional skin of atopic eczema
    • Wollenberg A, Kraft S, Hanau D, Bieber T. Immunomorphological and ultrastructural characterization of Langerhans cells and a novel, inflammatory dendritic epidermal cell (IDEC) population in lesional skin of atopic eczema. J Invest Dermatol 1996; 106: 446-53.
    • (1996) J Invest Dermatol , vol.106 , pp. 446-453
    • Wollenberg, A.1    Kraft, S.2    Hanau, D.3    Bieber, T.4
  • 37
    • 0030975867 scopus 로고    scopus 로고
    • Granulocyte macrophage colony-stimulating factor is overproduced by keratinocytes in atopic dermatitis. Implications for sustained dendritic cell activation in the skin
    • Pastore S, Fanales-Belasio E, Albanesi C, Chinni ML, Giannetti A, Girolomoni G. Granulocyte macrophage colony-stimulating factor is overproduced by keratinocytes in atopic dermatitis. Implications for sustained dendritic cell activation in the skin. J Clin Invest 1997; 99: 3009-17.
    • (1997) J Clin Invest , vol.99 , pp. 3009-3017
    • Pastore, S.1    Fanales-Belasio, E.2    Albanesi, C.3    Chinni, M.L.4    Giannetti, A.5    Girolomoni, G.6
  • 38
    • 0034521238 scopus 로고    scopus 로고
    • Dysregulated activation of activator protein 1 in keratinocytes of atopic dermatitis patients with enhanced expression of granulocyte/macrophage-colony stimulating factor
    • Pastore S, Giustizieri M, Mascia F, Giannetti A, Kaushansky K, Girolomoni G. Dysregulated activation of activator protein 1 in keratinocytes of atopic dermatitis patients with enhanced expression of granulocyte/macrophage-colony stimulating factor. J Invest Dermatol 2000; 115: 1134-43.
    • (2000) J Invest Dermatol , vol.115 , pp. 1134-1143
    • Pastore, S.1    Giustizieri, M.2    Mascia, F.3    Giannetti, A.4    Kaushansky, K.5    Girolomoni, G.6
  • 39
    • 0031445677 scopus 로고    scopus 로고
    • Intradermal transgenic expression of granulocyte-macrophage colonystimulating factor induces neutrophilia, epidermal hyperplasia, Langerhans cell/macrophage accumulation, and dermal fibrosis
    • Xing Z, Gauldie J, Tremblay GM, Hewlett BR, Addison C. Intradermal transgenic expression of granulocyte-macrophage colonystimulating factor induces neutrophilia, epidermal hyperplasia, Langerhans cell/macrophage accumulation, and dermal fibrosis. Lab Invest 1997; 77: 615-22.
    • (1997) Lab Invest , vol.77 , pp. 615-622
    • Xing, Z.1    Gauldie, J.2    Tremblay, G.M.3    Hewlett, B.R.4    Addison, C.5
  • 40
    • 0036301998 scopus 로고    scopus 로고
    • Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP
    • Soumelis V, Reche PA, Kanzler H, Yuan W, Edward G, Homey B, et al. Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP. Nat Immunol 2002; 3: 673-80.
    • (2002) Nat Immunol , vol.3 , pp. 673-680
    • Soumelis, V.1    Reche, P.A.2    Kanzler, H.3    Yuan, W.4    Edward, G.5    Homey, B.6
  • 42
    • 23944459169 scopus 로고    scopus 로고
    • Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin
    • Yoo J, Omori M, Gyarmati D, Zhou B, Aye T, Brewer A, Cormeau MR, Campbell DJ, Ziegler SF. Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin. J Exp Med 2005; 202: 541-9.
    • (2005) J Exp Med , vol.202 , pp. 541-549
    • Yoo, J.1    Omori, M.2    Gyarmati, D.3    Zhou, B.4    Aye, T.5    Brewer, A.6    Cormeau, M.R.7    Campbell, D.J.8    Ziegler, S.F.9
  • 43
    • 0036110388 scopus 로고    scopus 로고
    • Lack of association between atopic eczema/dermatitis syndrome and polymorphisms in the promoter region of RANTES and regulatory region of MCP-1
    • Kozma GT, Falus A, Bojszko A, Krikovszky D, Szabo T, Nagy A, Szalai C. Lack of association between atopic eczema/dermatitis syndrome and polymorphisms in the promoter region of RANTES and regulatory region of MCP-1. Allergy 2002; 57: 160-3.
    • (2002) Allergy , vol.57 , pp. 160-163
    • Kozma, G.T.1    Falus, A.2    Bojszko, A.3    Krikovszky, D.4    Szabo, T.5    Nagy, A.6    Szalai, C.7
  • 44
    • 10244250341 scopus 로고    scopus 로고
    • The immunogenetics of asthma and eczema: A new focus on the epithelium
    • Cookson W. The immunogenetics of asthma and eczema: a new focus on the epithelium. Nat Rev Immunol 2004; 4: 978-88.
    • (2004) Nat Rev Immunol , vol.4 , pp. 978-988
    • Cookson, W.1
  • 46
    • 13844294079 scopus 로고    scopus 로고
    • Signal transduction pathways in human epidermis
    • Iversen L, Johansen C, Kragballe K. Signal transduction pathways in human epidermis. Eur J Dermatol 2005; 15: 4-12.
    • (2005) Eur J Dermatol , vol.15 , pp. 4-12
    • Iversen, L.1    Johansen, C.2    Kragballe, K.3
  • 47
    • 0028953260 scopus 로고
    • Evidence that ceramide selectively inhibits protein kinase C-α translocation and modulates bradykinin activation of phospholipase D
    • Jones MJ, Murray AW. Evidence that ceramide selectively inhibits protein kinase C-α translocation and modulates bradykinin activation of phospholipase D. J Biol Chem 1995; 270: 5007-13.
    • (1995) J Biol Chem , vol.270 , pp. 5007-5013
    • Jones, M.J.1    Murray, A.W.2
  • 49
    • 17144371855 scopus 로고    scopus 로고
    • The cornified envelope: A model of cell death in the skin
    • Candi E, Schmidt R, Melino G. The cornified envelope: a model of cell death in the skin. Nat Rev Mol Cell Biol 2005; 6: 328-40.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 328-340
    • Candi, E.1    Schmidt, R.2    Melino, G.3
  • 50
    • 12344301866 scopus 로고    scopus 로고
    • Epidermal differentiation: The role of proteases and their inhibitors
    • Zeeuwen PLJM. Epidermal differentiation: the role of proteases and their inhibitors. Eur J Cell Biol 2004; 83: 761-73.
    • (2004) Eur J Cell Biol , vol.83 , pp. 761-773
    • Zeeuwen, P.L.J.M.1
  • 51
    • 20444446698 scopus 로고    scopus 로고
    • Serine proteinase inhibitors in the skin: Role in homeostasis and disease
    • Magert H-J, Drögemüller K, Raghunath M. Serine proteinase inhibitors in the skin: role in homeostasis and disease. Curr Protein Pept Sci 2005; 6: 241-54
    • (2005) Curr Protein Pept Sci , vol.6 , pp. 241-254
    • Magert, H.-J.1    Drögemüller, K.2    Raghunath, M.3
  • 52
    • 0037344315 scopus 로고    scopus 로고
    • Abnormal expression of the novel epidermal enzyme, glucosylceramide deacylase, and accumulation of its enzymatic reaction product, glucosylsphingosine, in the skin of patients with atopic dermatitis
    • Ishibashi M, Arikawa J, Okamoto R, Kawashima M, Takagi Y, Ohguchi K, et al. Abnormal expression of the novel epidermal enzyme, glucosylceramide deacylase, and accumulation of its enzymatic reaction product, glucosylsphingosine, in the skin of patients with atopic dermatitis. Lab Invest 2003; 83: 397-408.
    • (2003) Lab Invest , vol.83 , pp. 397-408
    • Ishibashi, M.1    Arikawa, J.2    Okamoto, R.3    Kawashima, M.4    Takagi, Y.5    Ohguchi, K.6
  • 54
    • 0036125252 scopus 로고    scopus 로고
    • Epidermal overexpression of stratum corneum chymotryptic enzyme in mice: A model for chronic itchy dermatitis
    • Hansson L, Backman A, Ny A, Edlund M, Ekholm E, Ekstrand Hammarstrom B, et al. Epidermal overexpression of stratum corneum chymotryptic enzyme in mice: a model for chronic itchy dermatitis. J Invest Dermatol 2002; 118: 444-9.
    • (2002) J Invest Dermatol , vol.118 , pp. 444-449
    • Hansson, L.1    Backman, A.2    Ny, A.3    Edlund, M.4    Ekholm, E.5    Ekstrand Hammarstrom, B.6
  • 55
    • 3042549544 scopus 로고    scopus 로고
    • Genetic association between an AACC insertion in the 3′UTR of the stratum corneum chymotryptic enzyme gene and atopic dermatitis
    • Vasilopoulos Y, Cork MJ, Murphy R, Williams HC, Robinson DA, Duff GW, et al. Genetic association between an AACC insertion in the 3′UTR of the stratum corneum chymotryptic enzyme gene and atopic dermatitis. J Invest Dermatol 2004; 123: 62-6.
    • (2004) J Invest Dermatol , vol.123 , pp. 62-66
    • Vasilopoulos, Y.1    Cork, M.J.2    Murphy, R.3    Williams, H.C.4    Robinson, D.A.5    Duff, G.W.6
  • 56
    • 26444570089 scopus 로고    scopus 로고
    • Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum corneum integrity
    • Hachem J-P, Man M-Q, Crumrine D, Uchida Y, Brown BE, Rogiers V, et al. Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum corneum integrity. J Invest Dermatol 2005; 125: 510-20.
    • (2005) J Invest Dermatol , vol.125 , pp. 510-520
    • Hachem, J.-P.1    Man, M.-Q.2    Crumrine, D.3    Uchida, Y.4    Brown, B.E.5    Rogiers, V.6
  • 57
  • 58
    • 19944427605 scopus 로고    scopus 로고
    • Spin/c5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity
    • Descargues P, Deraison C, Bonnart C, Kreft M, Kishibe M, Ishida-Yamamoto A, et al. Spin/c5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity. Nat Genet 2005; 37: 56-65.
    • (2005) Nat Genet , vol.37 , pp. 56-65
    • Descargues, P.1    Deraison, C.2    Bonnart, C.3    Kreft, M.4    Kishibe, M.5    Ishida-Yamamoto, A.6
  • 59
    • 19944431526 scopus 로고    scopus 로고
    • LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum
    • Ishida-Yamamoto A, Deraison C, Bonnart C, Bitoun E, Robinson R, O'Brien T, Wakamatsu K, et al. LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum. J Invest Dermatol 2005; 124: 360-6.
    • (2005) J Invest Dermatol , vol.124 , pp. 360-366
    • Ishida-Yamamoto, A.1    Deraison, C.2    Bonnart, C.3    Bitoun, E.4    Robinson, R.5    O'Brien, T.6    Wakamatsu, K.7
  • 61
    • 13444249470 scopus 로고    scopus 로고
    • Proteinase-activated receptors: Transducers of proteinase-mediated signaling in inflammation and immune response
    • Steinhoff M, Buddenkotte J, Shpacovitch V, Rattenholl A, Moormann C, Vergnolle N, et al. Proteinase-activated receptors: transducers of proteinase-mediated signaling in inflammation and immune response. Endocr Rev 2005; 26: 1-43.
    • (2005) Endocr Rev , vol.26 , pp. 1-43
    • Steinhoff, M.1    Buddenkotte, J.2    Shpacovitch, V.3    Rattenholl, A.4    Moormann, C.5    Vergnolle, N.6
  • 63
    • 17844404308 scopus 로고    scopus 로고
    • Involvement of mast cells in angiogenesis and chronic inflammation
    • Crivellato E, Ribatti D. Involvement of mast cells in angiogenesis and chronic inflammation. Curr Drug Targets Inflamm Allergy 2005; 4: 9-11.
    • (2005) Curr Drug Targets Inflamm Allergy , vol.4 , pp. 9-11
    • Crivellato, E.1    Ribatti, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.