메뉴 건너뛰기




Volumn 20, Issue 7, 2006, Pages 795-806

The novel SAM domain protein Aveugle is required for Raf activation in the Drosophila EGF receptor signaling pathway

Author keywords

EGFR; MAP kinase; Photoreceptor; Raf; Receptor tyrosine kinase; SAM

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; RAF PROTEIN;

EID: 33645521412     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1390506     Document Type: Article
Times cited : (24)

References (68)
  • 1
    • 0038782391 scopus 로고    scopus 로고
    • Pannier and pointedP2 act sequentially to regulate Drosophila heart development
    • Alvarez, A.D., Shi, W., Wilson, B.A., and Skeath, J.B. 2003. pannier and pointedP2 act sequentially to regulate Drosophila heart development. Development 130: 3015-3026.
    • (2003) Development , vol.130 , pp. 3015-3026
    • Alvarez, A.D.1    Shi, W.2    Wilson, B.A.3    Skeath, J.B.4
  • 2
    • 0037155242 scopus 로고    scopus 로고
    • Critical contribution of linker proteins to Raf kinase activation
    • Anselmo, A.N., Bumeister, R., Thomas, J.M., and White, M.A. 2002. Critical contribution of linker proteins to Raf kinase activation. J. Biol. Chem. 277: 5940-5943.
    • (2002) J. Biol. Chem. , vol.277 , pp. 5940-5943
    • Anselmo, A.N.1    Bumeister, R.2    Thomas, J.M.3    White, M.A.4
  • 3
    • 0033946836 scopus 로고    scopus 로고
    • Function and regulation of homothorax in the wing imaginal disc of Drosophila
    • Azpiazu, N. and Morata, G. 2000. Function and regulation of homothorax in the wing imaginal disc of Drosophila. Development 127: 2685-2693.
    • (2000) Development , vol.127 , pp. 2685-2693
    • Azpiazu, N.1    Morata, G.2
  • 4
    • 0345730824 scopus 로고    scopus 로고
    • A sensitized genetic screen to identify novel regulators and components of the Drosophila janus kinase/signal transducer and activator of transcription pathway
    • Bach, E.A., Vincent, S., Zeidler, M.P., and Perrimon, N. 2003. A sensitized genetic screen to identify novel regulators and components of the Drosophila janus kinase/signal transducer and activator of transcription pathway. Genetics 165: 1149-1166.
    • (2003) Genetics , vol.165 , pp. 1149-1166
    • Bach, E.A.1    Vincent, S.2    Zeidler, M.P.3    Perrimon, N.4
  • 5
    • 0036904830 scopus 로고    scopus 로고
    • Pointed and Tramtrack69 establish an EGFR-dependent transcriptional switch to regulate mitosis
    • Baonza, A., Murawsky, C.M., Travers, A.A., and Freeman, M. 2002. Pointed and Tramtrack69 establish an EGFR-dependent transcriptional switch to regulate mitosis. Nat. Cell Biol. 4: 976-980.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 976-980
    • Baonza, A.1    Murawsky, C.M.2    Travers, A.A.3    Freeman, M.4
  • 6
    • 0345306620 scopus 로고    scopus 로고
    • Binding of the C-terminal sterile α motif (SAM) domain of human p73 to lipid membranes
    • Barrera, F.N., Poveda, J.A., Gonzalez-Ros, J.M., and Neira, J.L. 2003. Binding of the C-terminal sterile α motif (SAM) domain of human p73 to lipid membranes. J. Biol. Chem. 278: 46878-46885.
    • (2003) J. Biol. Chem. , vol.278 , pp. 46878-46885
    • Barrera, F.N.1    Poveda, J.A.2    Gonzalez-Ros, J.M.3    Neira, J.L.4
  • 7
    • 0032582662 scopus 로고    scopus 로고
    • The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling
    • Bergmann, A., Agapite, J., McCall, K., and Steller, H. 1998. The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling. Cell 95: 331-341.
    • (1998) Cell , vol.95 , pp. 331-341
    • Bergmann, A.1    Agapite, J.2    McCall, K.3    Steller, H.4
  • 8
    • 14144255403 scopus 로고    scopus 로고
    • Polymerization of the SAM domain of MAPKKK Ste11 from the budding yeast: Implications for efficient signaling through the MAPK cascades
    • Bhattacharjya, S., Xu, P., Chakrapani, M., Johnston, L., and Ni, F. 2005. Polymerization of the SAM domain of MAPKKK Ste11 from the budding yeast: Implications for efficient signaling through the MAPK cascades. Protein Sci. 14: 828-835.
    • (2005) Protein Sci. , vol.14 , pp. 828-835
    • Bhattacharjya, S.1    Xu, P.2    Chakrapani, M.3    Johnston, L.4    Ni, F.5
  • 9
    • 0027533937 scopus 로고
    • Postembryonic patterns of expression of cut, a locus regulating sensory organ identity in Drosophila
    • Blochlinger, K., Jan, L.Y., and Jan, Y.N. 1993. Postembryonic patterns of expression of cut, a locus regulating sensory organ identity in Drosophila. Development 117: 441-450.
    • (1993) Development , vol.117 , pp. 441-450
    • Blochlinger, K.1    Jan, L.Y.2    Jan, Y.N.3
  • 10
    • 0035898539 scopus 로고    scopus 로고
    • Positive and negative regulation of Raf kinase activity and function by phosphorylation
    • Chong, H., Lee, J., and Guan, K.L. 2001. Positive and negative regulation of Raf kinase activity and function by phosphorylation. EMBO J. 20: 3716-3727.
    • (2001) EMBO J. , vol.20 , pp. 3716-3727
    • Chong, H.1    Lee, J.2    Guan, K.L.3
  • 11
    • 0037400510 scopus 로고    scopus 로고
    • Mechanisms of regulating the Raf kinase family
    • Chong, H., Vikis, H.G., and Guan, K.L. 2003. Mechanisms of regulating the Raf kinase family. Cell. Signal. 15: 463-469.
    • (2003) Cell. Signal. , vol.15 , pp. 463-469
    • Chong, H.1    Vikis, H.G.2    Guan, K.L.3
  • 12
    • 0036684674 scopus 로고    scopus 로고
    • Untying the regulation of the Raf-1 kinase
    • Dhillon, A.S. and Kolch, W. 2002. Untying the regulation of the Raf-1 kinase. Arch. Biochem. Biophys. 404: 3-9.
    • (2002) Arch. Biochem. Biophys. , vol.404 , pp. 3-9
    • Dhillon, A.S.1    Kolch, W.2
  • 14
    • 0345517108 scopus 로고    scopus 로고
    • Dual role for hedgehog in the regulation of the proneural gene atonal during ommatidia development
    • Dominguez, M. 1999. Dual role for hedgehog in the regulation of the proneural gene atonal during ommatidia development. Development 126: 2345-2353.
    • (1999) Development , vol.126 , pp. 2345-2353
    • Dominguez, M.1
  • 16
    • 0041529686 scopus 로고    scopus 로고
    • Protein kinase a blocks Raf-1 activity by stimulating 14-3-3 binding and blocking Raf-1 interaction with Ras
    • Dumaz, N. and Marais, R. 2003. Protein kinase A blocks Raf-1 activity by stimulating 14-3-3 binding and blocking Raf-1 interaction with Ras. J. Biol. Chem. 278: 29819-29823.
    • (2003) J. Biol. Chem. , vol.278 , pp. 29819-29823
    • Dumaz, N.1    Marais, R.2
  • 17
    • 0027364980 scopus 로고
    • Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase
    • Fabian, J.R., Daar, I.O., and Morrison, D.K. 1993. Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase. Mol. Cell. Biol. 13: 7170-7179.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7170-7179
    • Fabian, J.R.1    Daar, I.O.2    Morrison, D.K.3
  • 19
    • 0035829683 scopus 로고    scopus 로고
    • Senseless repression of rough is required for R8 photoreceptor differentiation in the developing Drosophila eye
    • Frankfort, B.J., Nolo, R., Zhang, Z., Bellen, H., and Mardon, G. 2001. senseless repression of rough is required for R8 photoreceptor differentiation in the developing Drosophila eye. Neuron 32: 403-414.
    • (2001) Neuron , vol.32 , pp. 403-414
    • Frankfort, B.J.1    Nolo, R.2    Zhang, Z.3    Bellen, H.4    Mardon, G.5
  • 20
    • 0030584086 scopus 로고    scopus 로고
    • Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye
    • Freeman, M. 1996. Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye. Cell 87: 651-660.
    • (1996) Cell , vol.87 , pp. 651-660
    • Freeman, M.1
  • 21
    • 0031051197 scopus 로고    scopus 로고
    • Cell determination strategies in the Drosophila eye
    • _. 1997. Cell determination strategies in the Drosophila eye. Development 124: 261-270.
    • (1997) Development , vol.124 , pp. 261-270
  • 22
    • 0029904093 scopus 로고    scopus 로고
    • EGF receptor signaling induces pointed P1 transcription and inactivates Yan protein in the Drosophila embryonic ventral ectoderm
    • Gabay, L., Scholz, H., Golembo, M., Klaes, A., Shilo, B.Z., and Klambt, C. 1996. EGF receptor signaling induces pointed P1 transcription and inactivates Yan protein in the Drosophila embryonic ventral ectoderm. Development 122: 3355-3362.
    • (1996) Development , vol.122 , pp. 3355-3362
    • Gabay, L.1    Scholz, H.2    Golembo, M.3    Klaes, A.4    Shilo, B.Z.5    Klambt, C.6
  • 23
    • 0030866482 scopus 로고    scopus 로고
    • In situ activation pattern of Drosophila EGF receptor pathway during development
    • Gabay, L., Seger, R., and Shilo, B.Z. 1997. In situ activation pattern of Drosophila EGF receptor pathway during development. Science 277: 1103-1106.
    • (1997) Science , vol.277 , pp. 1103-1106
    • Gabay, L.1    Seger, R.2    Shilo, B.Z.3
  • 24
    • 0029671192 scopus 로고    scopus 로고
    • Argos transcription is induced by the Drosophila EGF receptor pathway to form an inhibitory feedback loop
    • Golembo, M., Schweitzer, R., Freeman, M., and Shilo, B.Z. 1996. argos transcription is induced by the Drosophila EGF receptor pathway to form an inhibitory feedback loop. Development 122: 223-230.
    • (1996) Development , vol.122 , pp. 223-230
    • Golembo, M.1    Schweitzer, R.2    Freeman, M.3    Shilo, B.Z.4
  • 25
    • 0032774518 scopus 로고    scopus 로고
    • Rhomboid and Star interact synergistically to promote EGFR/MAPK signaling during Drosophila wing vein development
    • Guichard, A., Biehs, B., Sturtevant, M.A., Wickline, L., Chacko, J., Howard, K., and Bier, E. 1999. rhomboid and Star interact synergistically to promote EGFR/MAPK signaling during Drosophila wing vein development. Development 126: 2663-2676.
    • (1999) Development , vol.126 , pp. 2663-2676
    • Guichard, A.1    Biehs, B.2    Sturtevant, M.A.3    Wickline, L.4    Chacko, J.5    Howard, K.6    Bier, E.7
  • 26
    • 0027437850 scopus 로고
    • Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2
    • Gyuris, J., Golemis, E.A., Chertkov, H., and Brent, R. 1993. Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2. Cell 75: 791-803.
    • (1993) Cell , vol.75 , pp. 791-803
    • Gyuris, J.1    Golemis, E.A.2    Chertkov, H.3    Brent, R.4
  • 27
    • 0034981725 scopus 로고    scopus 로고
    • Ras controls growth, survival and differentiation in the Drosophila eye by different thresholds of MAP kinase activity
    • Halfar, K., Rommel, C., Stocker, H., and Hafen, E. 2001. Ras controls growth, survival and differentiation in the Drosophila eye by different thresholds of MAP kinase activity. Development 128: 1687-1696.
    • (2001) Development , vol.128 , pp. 1687-1696
    • Halfar, K.1    Rommel, C.2    Stocker, H.3    Hafen, E.4
  • 28
    • 0028795913 scopus 로고
    • Quantitative analysis of the complex between p21ras and the Rasbinding domain of the human Raf-1 protein kinase
    • Herrmann, C., Martin, G.A., and Wittinghofer, A. 1995. Quantitative analysis of the complex between p21ras and the Rasbinding domain of the human Raf-1 protein kinase. J. Biol. Chem. 270: 2901-2905.
    • (1995) J. Biol. Chem. , vol.270 , pp. 2901-2905
    • Herrmann, C.1    Martin, G.A.2    Wittinghofer, A.3
  • 29
    • 0026552381 scopus 로고
    • Dual Bar homeo box genes of Drosophila required in two photoreceptor cells, R1 and R6, and primary pigment cells for normal eye development
    • Higashijima, S.-I., Kojima, T., Michiue, T., Ishimaru, S., Emori, Y., and Saigo, K. 1992. Dual Bar homeo box genes of Drosophila required in two photoreceptor cells, R1 and R6, and primary pigment cells for normal eye development. Genes & Dev. 6: 50-60.
    • (1992) Genes & Dev. , vol.6 , pp. 50-60
    • Higashijima, S.-I.1    Kojima, T.2    Michiue, T.3    Ishimaru, S.4    Emori, Y.5    Saigo, K.6
  • 30
    • 1342323632 scopus 로고    scopus 로고
    • ErbB receptors: Directing key signaling networks throughout life
    • Holbro, T. and Hynes, N.E. 2004. ErbB receptors: Directing key signaling networks throughout life. Annu. Rev. Pharmacol. Toxicol. 44: 195-217.
    • (2004) Annu. Rev. Pharmacol. Toxicol. , vol.44 , pp. 195-217
    • Holbro, T.1    Hynes, N.E.2
  • 31
    • 1642362483 scopus 로고    scopus 로고
    • A mosaic genetic screen reveals distinct roles for trithorax and Polycomb group genes in Drosophila eye development
    • Janody, F., Lee, J.D., Jahren, N., Hazelett, D.J., Benlali, A., Miura, G.I., Draskovic, I., and Treisman, J.E. 2004. A mosaic genetic screen reveals distinct roles for trithorax and Polycomb group genes in Drosophila eye development. Genetics 166: 187-200.
    • (2004) Genetics , vol.166 , pp. 187-200
    • Janody, F.1    Lee, J.D.2    Jahren, N.3    Hazelett, D.J.4    Benlali, A.5    Miura, G.I.6    Draskovic, I.7    Treisman, J.E.8
  • 32
    • 0029069560 scopus 로고
    • Role of the proneural gene, atonal, in formation of Drosophila chordotonal organs and photoreceptors
    • Jarman, A.P., Sun, Y., Jan, L.Y., and Jan, Y.N. 1995. Role of the proneural gene, atonal, in formation of Drosophila chordotonal organs and photoreceptors. Development 121: 2019-2030.
    • (1995) Development , vol.121 , pp. 2019-2030
    • Jarman, A.P.1    Sun, Y.2    Jan, L.Y.3    Jan, Y.N.4
  • 33
    • 0035811597 scopus 로고    scopus 로고
    • Protein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactions
    • Jaumot, M. and Hancock, J.F. 2001. Protein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactions. Oncogene 20: 3949-3958.
    • (2001) Oncogene , vol.20 , pp. 3949-3958
    • Jaumot, M.1    Hancock, J.F.2
  • 34
    • 0035810047 scopus 로고    scopus 로고
    • Cdk10, a Cdc2-related kinase, associates with the Ets2 transcription factor and modulates its transactivation activity
    • Kasten, M. and Giordano, A. 2001. Cdk10, a Cdc2-related kinase, associates with the Ets2 transcription factor and modulates its transactivation activity. Oncogene 20: 1832-1838.
    • (2001) Oncogene , vol.20 , pp. 1832-1838
    • Kasten, M.1    Giordano, A.2
  • 36
    • 0036260660 scopus 로고    scopus 로고
    • The SAM domain of polyhomeotic forms a helical polymer
    • Kim, C.A., Gingery, M., Pilpa, R.M., and Bowie, J.U. 2002. The SAM domain of polyhomeotic forms a helical polymer. Nat. Struct. Biol. 9: 453-457.
    • (2002) Nat. Struct. Biol. , vol.9 , pp. 453-457
    • Kim, C.A.1    Gingery, M.2    Pilpa, R.M.3    Bowie, J.U.4
  • 37
    • 4344611655 scopus 로고    scopus 로고
    • Argos inhibits epidermal growth factor receptor signalling by ligand sequestration
    • Klein, D.E., Nappi, V.M., Reeves, G.T., Shvartsman, S.Y., and Lemmon, M.A. 2004. Argos inhibits epidermal growth factor receptor signalling by ligand sequestration. Nature 430: 1040-1044.
    • (2004) Nature , vol.430 , pp. 1040-1044
    • Klein, D.E.1    Nappi, V.M.2    Reeves, G.T.3    Shvartsman, S.Y.4    Lemmon, M.A.5
  • 39
    • 0032582793 scopus 로고    scopus 로고
    • Ras promotes cell survival in Drosophila by downregulating hid expression
    • Kurada, P. and White, K. 1998. Ras promotes cell survival in Drosophila by downregulating hid expression. Cell 95: 319-329.
    • (1998) Cell , vol.95 , pp. 319-329
    • Kurada, P.1    White, K.2
  • 40
    • 0031940786 scopus 로고    scopus 로고
    • Dorsotonals/homothorax, the Drosophila homologue of meis1, interacts with extradenticle in patterning of the embryonic PNS
    • Kurant, E., Pai, C.Y., Sharf, R., Halachmi, N., Sun, Y.H., and Salzberg, A. 1998. Dorsotonals/homothorax, the Drosophila homologue of meis1, interacts with extradenticle in patterning of the embryonic PNS. Development 125: 1037-1048.
    • (1998) Development , vol.125 , pp. 1037-1048
    • Kurant, E.1    Pai, C.Y.2    Sharf, R.3    Halachmi, N.4    Sun, Y.H.5    Salzberg, A.6
  • 41
    • 14844303687 scopus 로고    scopus 로고
    • Src42 binding activity regulates Drosophila RAF by a novel CNK-dependent derepression mechanism
    • Laberge, G., Douziech, M., and Therrien, M. 2005. Src42 binding activity regulates Drosophila RAF by a novel CNK-dependent derepression mechanism. EMBO J. 24: 487-498.
    • (2005) EMBO J. , vol.24 , pp. 487-498
    • Laberge, G.1    Douziech, M.2    Therrien, M.3
  • 42
    • 0028724937 scopus 로고
    • In situ hybridization to RNA
    • Lehmann, R. and Tautz, D. 1994. In situ hybridization to RNA. Methods Cell Biol. 44: 575-598.
    • (1994) Methods Cell Biol. , vol.44 , pp. 575-598
    • Lehmann, R.1    Tautz, D.2
  • 43
    • 0037145505 scopus 로고    scopus 로고
    • The proteasome regulatory particle subunit Rpn6 is required for Drosophila development and interacts physically with signalosome subunit Alien/CSN2
    • Lier, S. and Paululat, A. 2002. The proteasome regulatory particle subunit Rpn6 is required for Drosophila development and interacts physically with signalosome subunit Alien/CSN2. Gene 298: 109-119.
    • (2002) Gene , vol.298 , pp. 109-119
    • Lier, S.1    Paululat, A.2
  • 44
    • 0029006126 scopus 로고
    • Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation
    • Marais, R., Light, Y., Paterson, H.F., and Marshall, C.J. 1995. Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation. EMBO J. 14: 3136-3145.
    • (1995) EMBO J. , vol.14 , pp. 3136-3145
    • Marais, R.1    Light, Y.2    Paterson, H.F.3    Marshall, C.J.4
  • 45
    • 0342514710 scopus 로고    scopus 로고
    • A temporal switch in der signaling controls the specification and differentiation of veins and interveins in the Drosophila wing
    • Martin-Blanco, E., Roch, F., Noll, E., Baonza, A., Duffy, J.B., and Perrimon, N. 1999. A temporal switch in DER signaling controls the specification and differentiation of veins and interveins in the Drosophila wing. Development 126: 5739-5747.
    • (1999) Development , vol.126 , pp. 5739-5747
    • Martin-Blanco, E.1    Roch, F.2    Noll, E.3    Baonza, A.4    Duffy, J.B.5    Perrimon, N.6
  • 46
    • 0037429739 scopus 로고    scopus 로고
    • The epidermal growth factor system in Caenorhabditis elegans
    • Moghal, N. and Sternberg, P.W. 2003. The epidermal growth factor system in Caenorhabditis elegans. Exp. Cell Res. 284: 150-159.
    • (2003) Exp. Cell Res. , vol.284 , pp. 150-159
    • Moghal, N.1    Sternberg, P.W.2
  • 47
    • 0035018017 scopus 로고    scopus 로고
    • KSR: A MAPK scaffold of the Ras pathway?
    • Morrison, D.K. 2001. KSR: A MAPK scaffold of the Ras pathway? J. Cell Sci. 114: 1609-1612.
    • (2001) J. Cell Sci. , vol.114 , pp. 1609-1612
    • Morrison, D.K.1
  • 48
    • 0027410497 scopus 로고
    • The MAP kinase cascade is essential for diverse signal transduction pathways
    • Nishida, E. and Gotoh, Y. 1993. The MAP kinase cascade is essential for diverse signal transduction pathways. Trends Biochem. Sci. 18: 128-131.
    • (1993) Trends Biochem. Sci. , vol.18 , pp. 128-131
    • Nishida, E.1    Gotoh, Y.2
  • 50
    • 0038112138 scopus 로고    scopus 로고
    • The role of adaptor protein Ste50-dependent regulation of the MAPKKK Ste11 in multiple signalling pathways of yeast
    • Ramezani-Rad, M. 2003. The role of adaptor protein Ste50-dependent regulation of the MAPKKK Ste11 in multiple signalling pathways of yeast. Curr. Genet. 43: 161-170.
    • (2003) Curr. Genet. , vol.43 , pp. 161-170
    • Ramezani-Rad, M.1
  • 51
    • 23844458596 scopus 로고    scopus 로고
    • Caenorhabditis elegans CNK-1 promotes Raf activation but is not essential for Ras/Raf signaling
    • Rocheleau, C.E., Ronnlund, A., Tuck, S., and Sundaram, M.V. 2005. Caenorhabditis elegans CNK-1 promotes Raf activation but is not essential for Ras/Raf signaling. Proc. Natl. Acad. Sci. 102: 11757-11762.
    • (2005) Proc. Natl. Acad. Sci. , vol.102 , pp. 11757-11762
    • Rocheleau, C.E.1    Ronnlund, A.2    Tuck, S.3    Sundaram, M.V.4
  • 54
    • 0037145061 scopus 로고    scopus 로고
    • Ligand-induced, receptor-mediated dimerization and activation of EGF receptor
    • Schlessinger, J. 2002. Ligand-induced, receptor-mediated dimerization and activation of EGF receptor. Cell 110: 669-672.
    • (2002) Cell , vol.110 , pp. 669-672
    • Schlessinger, J.1
  • 55
    • 0036142763 scopus 로고    scopus 로고
    • An ERK2 docking site in the Pointed domain distinguishes a subset of ETS transcription factors
    • Seidel, J.J. and Graves, B.J. 2002. An ERK2 docking site in the Pointed domain distinguishes a subset of ETS transcription factors. Genes & Dev. 16: 127-137.
    • (2002) Genes & Dev. , vol.16 , pp. 127-137
    • Seidel, J.J.1    Graves, B.J.2
  • 57
    • 0032948019 scopus 로고    scopus 로고
    • The crystal structure of an Eph receptor SAM domain reveals a mechanism for modular dimerization
    • Stapleton, D., Balan, I., Pawson, T., and Sicheri, F. 1999. The crystal structure of an Eph receptor SAM domain reveals a mechanism for modular dimerization. Nat. Struct. Biol. 6: 44-49.
    • (1999) Nat. Struct. Biol. , vol.6 , pp. 44-49
    • Stapleton, D.1    Balan, I.2    Pawson, T.3    Sicheri, F.4
  • 58
    • 0029850713 scopus 로고    scopus 로고
    • KSR modulates signal propagation within the MAPK cascade
    • Therrien, M., Michaud, N.R., Rubin, G.M., and Morrison, D.K. 1996. KSR modulates signal propagation within the MAPK cascade. Genes & Dev. 10: 2684-2695.
    • (1996) Genes & Dev. , vol.10 , pp. 2684-2695
    • Therrien, M.1    Michaud, N.R.2    Rubin, G.M.3    Morrison, D.K.4
  • 59
    • 0032582663 scopus 로고    scopus 로고
    • CNK, a RAF-binding multidomain protein required for RAS signaling
    • Therrien, M., Wong, A.M., and Rubin, G.M. 1998. CNK, a RAF-binding multidomain protein required for RAS signaling. Cell 95: 343-353.
    • (1998) Cell , vol.95 , pp. 343-353
    • Therrien, M.1    Wong, A.M.2    Rubin, G.M.3
  • 61
    • 0037031590 scopus 로고    scopus 로고
    • An EGFR/Ebi/Sno pathway promotes Delta expression by inactivating Su(H)/SMRTER repression during inductive Notch signaling
    • Tsuda, L., Nagaraj, R., Zipursky, S.L., and Banerjee, U. 2002. An EGFR/Ebi/Sno pathway promotes Delta expression by inactivating Su(H)/SMRTER repression during inductive Notch signaling. Cell 110: 625-637.
    • (2002) Cell , vol.110 , pp. 625-637
    • Tsuda, L.1    Nagaraj, R.2    Zipursky, S.L.3    Banerjee, U.4
  • 62
    • 0034665738 scopus 로고    scopus 로고
    • Dual role for Drosophila epidermal growth factor receptor signaling in early wing disc development
    • Wang, S.H., Simcox, A., and Campbell, G. 2000. Dual role for Drosophila epidermal growth factor receptor signaling in early wing disc development. Genes & Dev. 14: 2271-2276.
    • (2000) Genes & Dev. , vol.14 , pp. 2271-2276
    • Wang, S.H.1    Simcox, A.2    Campbell, G.3
  • 64
    • 0034730329 scopus 로고    scopus 로고
    • Overlapping activators and repressors delimit transcriptional response to receptor tyrosine kinase signals in the Drosophila eye
    • Xu, C., Kauffmann, R.C., Zhang, J., Kladny, S., and Carthew, R.W. 2000. Overlapping activators and repressors delimit transcriptional response to receptor tyrosine kinase signals in the Drosophila eye. Cell 103: 87-97.
    • (2000) Cell , vol.103 , pp. 87-97
    • Xu, C.1    Kauffmann, R.C.2    Zhang, J.3    Kladny, S.4    Carthew, R.W.5
  • 65
    • 0037343951 scopus 로고    scopus 로고
    • Cell cycle withdrawal, progression, and cell survival regulation by EGFR and its effectors in the differentiating Drosophila eye
    • Yang, L. and Baker, N.E. 2003. Cell cycle withdrawal, progression, and cell survival regulation by EGFR and its effectors in the differentiating Drosophila eye. Dev. Cell 4: 359-369.
    • (2003) Dev. Cell , vol.4 , pp. 359-369
    • Yang, L.1    Baker, N.E.2
  • 67
    • 0036336652 scopus 로고    scopus 로고
    • Subdivision of the Drosophila wing imaginal disc by EGFR-mediated signaling
    • Zecca, M. and Struhl, G. 2002. Subdivision of the Drosophila wing imaginal disc by EGFR-mediated signaling. Development 129: 1357-1368.
    • (2002) Development , vol.129 , pp. 1357-1368
    • Zecca, M.1    Struhl, G.2
  • 68
    • 0034675919 scopus 로고    scopus 로고
    • Activation of B-Raf kinase requires phosphorylation of the conserved residues Thr598 and Ser601
    • Zhang, B.H. and Guan, K.L. 2000. Activation of B-Raf kinase requires phosphorylation of the conserved residues Thr598 and Ser601. EMBO J. 19: 5429-5439.
    • (2000) EMBO J. , vol.19 , pp. 5429-5439
    • Zhang, B.H.1    Guan, K.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.