Src42 binding activity regulates Drosophila RAF by a novel CNK-dependent derepression mechanism

EMBO Journal

Volumn 24, Issue 3, 2005, Pages 487-498

  Laberge, Gino ^a   Douziech, Mélanie ^a   Therrien, Marc ^a  

^a INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

Author keywords

CNK; MAPK module; RAF; RAS; SFK

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN CNK; PROTEIN KINASE SRC42; PROTEIN TYROSINE KINASE; RAF PROTEIN; UNCLASSIFIED DRUG;

ALLELE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; DROSOPHILA; ENZYME ACTIVATION; EYE DEVELOPMENT; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; SCANNING ELECTRON MICROSCOPY; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; DROSOPHILA; DROSOPHILA PROTEINS; ENZYME ACTIVATION; EYE; MAP KINASE SIGNALING SYSTEM; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RAF KINASES; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SRC HOMOLOGY DOMAINS; TYROSINE;

EID: 14844303687     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600558     Document Type: Article

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